Pharmacology Of Hormonal Polypeptides And Proteins
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Pharmacology Of Hormonal Polypeptides And Proteins
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Author : Nathan Back
language : en
Publisher: Springer
Release Date : 2013-12-11
Pharmacology Of Hormonal Polypeptides And Proteins written by Nathan Back and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-12-11 with Medical categories.
It can be concluded (under the specific experimental procedures em ployed) that:- 1) HCG labelled with 1 - 2 atoms of radioactive iodine did not differ sig nificantly from the unlabelled hormone; 2) The ovary alone exhibited a capacity to affix specifically HCG; 3) The amount of radioactive material in the ovary was directly proport ional to the quantity of labelled HCG injected; 4) When the HCG present in the circulation is bound to an antiserum to HCG, the antigen-antibody complex is not concentrated by the ovary; 5) Circulating labelled HCG decreased to 50% within 30 minutes following a single intravenous injection; 6) There are four different phases of ovarian uptake of HCG, namely: the first phase, when there is only an inflow from the circulation and stor age mainly in the follicular envelopes; the second phase, when there is a greater inflow than outflow; the third phase, when the inflow is equal to the outflow; and the fourth period, when the outflow is bigger than the in flow. REFERENCES 1. Lunenfeld, B. and Eshkol, A. Vitamins and Hormones (1967) 25:165 2. Eshkol, A. In: Recent Research on Gonadotropbio Hormones, eds. E. T. Bell andJ. A. Loraine, Edinburgh, Livingstone (1967), p. 202. 3. Eshkol, A. and Lunenfeld, B. Proc. Tel-Hashomer Hosp. (1967) 6:4. ACKNOWLEOOMEN'IS This work was supported in part by a grant from the Population Council, N. Y. , U. S. A. andbyGrantNo.
Pharmacology Of Hormonal Polypeptides And Proteins
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Author : Nathan Back
language : en
Publisher:
Release Date : 2014-09-01
Pharmacology Of Hormonal Polypeptides And Proteins written by Nathan Back and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-09-01 with categories.
Pharmacology Of Hormonal Polypeptides And Proteins
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Author : Nathan Back
language : en
Publisher:
Release Date : 1968
Pharmacology Of Hormonal Polypeptides And Proteins written by Nathan Back and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1968 with categories.
Pharmacology Of Hormonal Polypeptides And Proteins
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Author : Italy) International Symposium on the Pharmacology of Hormonal Polypeptides (1967: Milan
language : en
Publisher:
Release Date : 1968
Pharmacology Of Hormonal Polypeptides And Proteins written by Italy) International Symposium on the Pharmacology of Hormonal Polypeptides (1967: Milan and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1968 with categories.
Pharmacology Of Hormonal Polypeptides And Proteins
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Author : Nathan Back
language : en
Publisher:
Release Date :
Pharmacology Of Hormonal Polypeptides And Proteins written by Nathan Back and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.
Pharmacology Of Hormonal Polypeptides And Proteins Proceedings Of An International Symposium
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Author : Nathan Black
language : en
Publisher:
Release Date : 1968
Pharmacology Of Hormonal Polypeptides And Proteins Proceedings Of An International Symposium written by Nathan Black and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1968 with Peptide hormones categories.
Pharmacology Of Hormonal Polypeptides And Proteins
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Author : Nathan Back
language : en
Publisher:
Release Date : 1968
Pharmacology Of Hormonal Polypeptides And Proteins written by Nathan Back and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1968 with categories.
Peptides
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Author : Bernd Gutte
language : en
Publisher: Elsevier
Release Date : 1995-10-24
Peptides written by Bernd Gutte and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995-10-24 with Science categories.
In recent years, research has shown the importance of peptides in neuroscience, immunology, and cell biology. Active research programs worldwide are now engaged in developing peptide-based drugs and vaccines using modification of natural peptides and proteins, design of artificial peptides and peptide mimetics, and screening of peptide and phage libraries. In this comprehensive book, the authors discuss peptide synthesis and application within the context of their increasing importance to the pharmaceutical industry. Peptides: Synthesis, Structures, and Applications explores the broad growth of information in modern peptide synthetic methods and the structure-activity relationships of synthetic polypeptides. The history of peptide chemistry Amide formation, deprotection, and disulfide formation in peptide synthesis Solid-phase peptide synthesis a-helix formation by peptides in water Stability and dynamics of peptide conformation An overview of structure-function studies of peptide hormones Neuropeptides:peptide and nonpeptide analogs Reversible inhibitors of serine proteinases Design of polypeptides Current capabilities and future possibilities of soluble chemical combinatorial libraries Epitope mapping with peptides Synthesis and applications of branched peptides in immunological methods and vaccines
Therapeutic Peptides And Proteins
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Author : Ajay K. Banga
language : en
Publisher: CRC Press
Release Date : 1997-07-01
Therapeutic Peptides And Proteins written by Ajay K. Banga and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997-07-01 with Medical categories.
From the Preface At the time of this writing, the American biotechnology and pharmaceutical industry has more than two dozen biotechnology-derived therapeutic proteins on the market, while several hundred are in various stages of human clinical trials or at the FDA for review. Today, more than a thousand companies are involved in biotechnology research, with a total revenue of $7.7 billion for 1993. Therapeutic peptides and proteins are expected to mitigate suffering in coming years as anticancer agents, hormones, growth factors, analgesics, anti-hypertensives, and thrombolytics, among others. However, the clinical application of these therapeutic peptides and proteins is limited by several problems, such as lack of physical and chemical stability or the lack of desirable attributes for adequate absorption or distribution. Thus, as these therapeutic peptides and proteins are made available, it will be essential to formulate these drugs into safe, stable and efficacious delivery systems. The pharmaceutical scientist involved in this effort needs to call upon the knowledge of several disciplines, such as pharmaceutics, medicinal chemistry, biochemistry, and microbiology, and needs to keep abreast with the latest research in the published literature. This book presents these principles in a simple, interesting and practically useful manner for the benefit of scientists working in this area and to further research in this area. This book will also provide useful information for students and academic researchers and add to their interest in this area. The book should also be useful in a hospital setting to understand potential physicochemical stability problems that may result during reconstitution or administration of the new recombinant proteins. Since this field is relatively new and rapidly evolving, efforts were made to include very recent literature in the book. As a result, over 40% of the literature citations in the book are for the work published in the last two years.
Stability And Characterization Of Protein And Peptide Drugs
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Author : Rodney Pearlman
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-29
Stability And Characterization Of Protein And Peptide Drugs written by Rodney Pearlman and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-29 with Medical categories.
This is the first volume to make available specific case histories of therapeutic proteins and peptides that have been marketed or are currently under clinical testing. The editors have selected a wide range of molecules derived from monoclonal antibodies, recombinant DNA, and natural and chemical sources to provide formulation scientists with practical examples of the development of pharmaceutical products.