Pharmacometrics
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Pharmacometrics
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Author : Ene I. Ette
language : en
Publisher: John Wiley & Sons
Release Date : 2013-03-14
Pharmacometrics written by Ene I. Ette and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-14 with Medical categories.
Pharmacometrics is the science of interpreting and describing pharmacology in a quantitative fashion. The pharmaceutical industry is integrating pharmacometrics into its drug development program, but there is a lack of and need for experienced pharmacometricians since fewer and fewer academic programs exist to train them. Pharmacometrics: The Science of Quantitative Pharmacology lays out the science of pharmacometrics and its application to drug development, evaluation, and patient pharmacotherapy, providing a comprehensive set of tools for the training and development of pharmacometricians. Edited and written by key leaders in the field, this flagship text on pharmacometrics: Integrates theory and practice to let the reader apply principles and concepts. Provides a comprehensive set of tools for training and developing expertise in the pharmacometric field. Is unique in including computer code information with the examples. This volume is an invaluable resource for all pharmacometricians, statisticians, teachers, graduate and undergraduate students in academia, industry, and regulatory agencies.
Applied Pharmacometrics
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Author : Stephan Schmidt
language : en
Publisher: Springer
Release Date : 2014-12-01
Applied Pharmacometrics written by Stephan Schmidt and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-12-01 with Medical categories.
This comprehensive volume provides an update on the current state of pharmacometrics in drug development. It consists of nineteen chapters all written by leading scientists from the pharmaceutical industry, regulatory agencies and academia. After an introduction of the basic pharmacokinetic and pharmacodynamic concepts of pharmacometrics in drug development, the book presents numerous examples of specific applications that utilize pharmacometrics with modeling and simulations over a variety of therapeutic areas, including pediatrics, diabetes, obesity, infections, psychiatrics, Alzheimer’s disease, and dermatology, among others. The examples illustrate how results from all phases of drug development can be integrated in a more timely and cost-effective process. Applying pharmacometric decision tools during drug development can allow objective, data-based decision making. At the same time, the process can identify redundant or unnecessary experiments as well as some costly clinical trials that can be avoided. In addition to cost saving by expedited development of successful drug candidates, pharmacometrics has an important economic impact in drug product selection. Unsuccessful drug candidates can be identified early and discontinued without expending efforts required for additional studies and allocating limited resources. Hence, pharmacometric modeling and simulation has become a powerful tool to bring new and better medications to the patient at a faster pace and with greater probability of success.
Evaluation Of Drug Activities
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Author : D R Laurence
language : en
Publisher: Elsevier
Release Date : 2013-10-22
Evaluation Of Drug Activities written by D R Laurence and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-22 with Medical categories.
Evaluation of Drug Activities: Pharmacometrics, Volume 2 provides information pertinent to the fundamental aspects of pharmacometrics. This book covers a variety of topics, including anticholinesterases, antitussives, cardioactive agents, diuretics, dermatological agents, and estrogens. Organized into 21 chapters, this volume begins with an overview of anticholinesterases and its pharmacological and physiological actions. This text then examines the diversity of methods for evaluating antitussive drugs, which is related to the complexity of cough reflexes. Other chapters consider tests for cardioactive substances of three general classes, namely, the cardiac glycosides, the coronary vasodilators, and the anti-arrhythmics. This book discusses as well the introduction of many diuretics into therapeutic practice during the past years bears witness to the convenience and success of the tests available for assessing drugs of this class. The final chapter deals with drugs affecting lipid levels in plasma. This book is a valuable resource for chemists, physiologists, pharmacologists, and clinicians.
Evaluation Of Drug Activities
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Author : Alfred Louis Bacharach
language : en
Publisher:
Release Date : 1964
Evaluation Of Drug Activities written by Alfred Louis Bacharach and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1964 with Drugs categories.
Innovative Pharmacometric Approaches To Inform Drug Development And Clinical Use
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Author : Zinnia P. Parra-Guillen
language : en
Publisher: Frontiers Media SA
Release Date : 2024-02-21
Innovative Pharmacometric Approaches To Inform Drug Development And Clinical Use written by Zinnia P. Parra-Guillen and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-02-21 with Science categories.
Pharmacometrics represents a strategy to optimize and rationalize decision-making process integrating information on drug behavior, pharmacological response, and disease progression both in the drug development phases and in their clinical use. Pharmacometrics focuses on characterizing the pharmacokinetic and pharmacodynamic behavior of one or several active ingredients through the development of mathematical and statistical models that allow characterizing both the average behavior in the population and the different sources of variability. Currently, pharmacometrics has transformed drug development and therapeutic use paradigm, which yield to the recognition by the main regulatory agencies (FDA, EMA, and PMDA).
Evaluation Of Drug Activities
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Author : D. R. Laurence
language : en
Publisher:
Release Date : 2013
Evaluation Of Drug Activities written by D. R. Laurence and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013 with categories.
Evaluation of Drug Activities ...
The Emerging Scientific Discipline Of Pharmacometrics
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Author : Marc Pfister
language : en
Publisher:
Release Date : 2010
The Emerging Scientific Discipline Of Pharmacometrics written by Marc Pfister and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010 with categories.
Pharmacometrics For Treatment Optimization And Drug Development In Oncology
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Author :
language : en
Publisher:
Release Date : 2019
Pharmacometrics For Treatment Optimization And Drug Development In Oncology written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019 with categories.
Pharmacometrics For Combination Therapy In Oncology
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Author : Marcus Baaz
language : en
Publisher:
Release Date : 2024
Pharmacometrics For Combination Therapy In Oncology written by Marcus Baaz and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024 with Mathematical models categories.
Evaluation Of Drug Activities Pharmacometrics Edited By D R Laurence And A L Bacharach By Various Authors
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Author : Desmond Roger LAURENCE (and BACHARACH (Alfred Louis))
language : en
Publisher:
Release Date : 1964
Evaluation Of Drug Activities Pharmacometrics Edited By D R Laurence And A L Bacharach By Various Authors written by Desmond Roger LAURENCE (and BACHARACH (Alfred Louis)) and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1964 with Pharmacokinetics categories.