Phylogenetic Perspectives On The Vertebrate Immune System
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Phylogenetic Perspectives On The Vertebrate Immune System
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Author : Gregory Becker
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Phylogenetic Perspectives On The Vertebrate Immune System written by Gregory Becker and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
This book contains the proceedings of the first meeting on invertebrate immunity ever sponsored as a summer research conference by the Federation of American Societies for Experimental Biology (FASEB). The conference was held in Copper Mountain, CO from July 11-16, 1999. It was a an extension of a New York Academy of Sciences meeting entitled "Primordial Immunity: Foundations for the Vertebrate Immune System" held on May 2-5,1993 at the Marine Biological Laboratories in Woods Hole, MA. The proceedings of that meeting were published in The Annals of the New York Academy of Sciences (volume 712). At that meeting all the attendes agreed that this type of conference (a relatively small focused gathering) allowed for participation by investigators at all levels of their careers. We further agreed that we should search for a forum that would allow this meeting to continue. The FASEB Summer Research Conference was an excellent vehicle for this type of meeting. Furthermore, this year's participants decided to continue this meeting as a regularly scheduled FASEB sponsored event. This was a unique conference in the sense that it focused upon mechanisms of development and defense in protostome and deuterostome invertebrates and lower vertebrates. There was a strong emphasis on evolutionary cell biology, phylogenetic inferences and the evolution of recognition and regulatory systems.
Phylogenetic Perspectives In Immunity
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Author : Jules Hoffmann
language : en
Publisher: R. G. Landes
Release Date : 1994
Phylogenetic Perspectives In Immunity written by Jules Hoffmann and has been published by R. G. Landes this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994 with Medical categories.
Changing Views Of The Evolution Of Immunity
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Author : Gary W. Litman
language : en
Publisher: Frontiers E-books
Release Date : 2014-01-22
Changing Views Of The Evolution Of Immunity written by Gary W. Litman and has been published by Frontiers E-books this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-01-22 with categories.
The multitude of cells, signaling pathways, receptors, novel genetic recombination mechanisms and interactive pathways of receptor function and cell differentiation that constitute the vertebrate adaptive immune system are integrally linked with the multicomponent innate immune system. At first glance, the levels of complexity seen in both systems at the phylogenetic level of mammals present what seem to be insurmountable hurdles in terms of achieving a systematic understanding of the evolution of immunity. New research directions and approaches suggest that resolution of many long-standing questions in this area is now possible. Historically, immunologists considered lower vertebrates and invertebrates as “simpler” forms, i.e., they were expected to possess more basic (less layered) levels of immunological complexity and thus potentially would serve as important resources. By considering the systematic placement of representative species in the context of phylogeny, characterizing their immune receptors, co-receptors as well as accessory molecules and evaluating responses to immunologic stimuli, it was thought that a clearer picture of immune evolution would emerge. There is no doubt that this approach has achieved some notable successes but for the most part it has fallen short in terms of achieving a broad understanding of the immunologic needs of many relevant models and how adaptive change in immune function is effected. Even if a structurally relevant ortholog of an immune effector is identified in a model organism, there is no reason to assume that it functions in a corresponding manner in disparate phylogenetic taxa. For example, survival of a sessile marine invertebrate, whose anatomical form puts it in open and contiguous contact with a literal sea of microorganisms and viruses, would be thought to depend, at least in part, on a “capable” immune response; however, at present, we have no real understanding of how this is achieved in an integrated manner. Furthermore, questions arise as to whether or not phenomena that are considered integral components of vertebrate-type immunity such as memory, tolerance, somatic change and clonal selection exist in invertebrates and if their functions parallel those recognized in mammals. More often than not, our interpretations are guided by preconceived notions that are based on observations made in distant species that often do not apply to far- removed taxa. We anticipate that major advances in our understanding of this broad subject are now forthcoming as resources exist or are being developed for examining important model organisms in their natural environments instead of within the confines of in vitro systems of potentially remote physiological significance. Taking a wide range of hypotheses, observations and interpretations into account, in this special topic, contributors have developed a comprehensive overview emphasizing new directions and interpretations for understanding basic aspects of immunity that consider unique features inherent to various model systems, their life histories and habitats. Approaches applied with key model organisms maintained and confronted with relevant challenges under natural conditions are emphasized. Current concepts of self and nonself are addressed not only in terms of immunity but also reproductive fitness. How genetic variation in immune effector molecules is achieved and maintained in natural populations is examined; particular attention is directed to response interfaces that factor in symbiotic interactions. Gene expansion and mechanisms of genetic diversification are explored. How diverse molecules and a variety of effector cells contribute to our broad understanding of the evolution of a remarkably complex, integrated system and how this work is facilitating our understanding of mammalian immunity is addressed.
Phylogenetic Development Of Vertebrate Immunity
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Author : Joel M. Goodman
language : en
Publisher: Ardent Media
Release Date : 1972
Phylogenetic Development Of Vertebrate Immunity written by Joel M. Goodman and has been published by Ardent Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 1972 with Medical categories.
Phylogenetic Development Vertebrate Immunity
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Author :
language : en
Publisher:
Release Date : 1972
Phylogenetic Development Vertebrate Immunity written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1972 with categories.
Origin And Evolution Of The Vertebrate Immune System
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Author : L. Du Pasquier
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Origin And Evolution Of The Vertebrate Immune System written by L. Du Pasquier and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
The comparative approach to immunology can be traced to the era of Pasteur and Metchnikov in which observations regarding foreign recognition in invertebrates was a factor in the develop ment of the principal concepts that created the foundation of what now is the broad field of immunology. With each major experimental and conceptual breakthrough, the classical, albeit essential, question has been asked "are the immune systems of phylogenetically primitive vertebrates and invertebrates similar to that of mammals?" Somewhat surprisingly for the jawed verte brates, the general answer has been a qualified form of "yes", whereas for agnathans and invertebrate phyla it has been "no" so far. The apparent abruptness in the appearance of the immune system of vertebrates is linked to the introduction of the somatic generation of the diversity of its antigen specific receptors. Therefore the questions regarding the origin and evolution of the specific immune system revolve around this phenomenon. With respect to the origin of the system (aside from the or igin of the rearranging machinery itself, the study of which is still in its infancy) one can ask questions about the cellular and mo lecular contexts in which the mechanism was introduced.
Natural Immunity
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Author : Lorand Bertok
language : en
Publisher: Elsevier
Release Date : 2005-04-11
Natural Immunity written by Lorand Bertok and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-04-11 with Medical categories.
"Natural Immunity" is a broadly-based account of the activities of the evolutionarily conserved molecules, cells and processes of the natural immune system. This encompasses the early host protection against microbes (bacteria and viruses) and tumours, prior to the generation of the adaptive immune response, diverse major current pathologies including inflammatory and autoimmune diseases, and key roles in essential physiological processes such as reproduction and wound healing. The first comprehensive book on natural immunity Reviews new topics, effects of behaviour, aging, and exercise, and diet on natural immunity Highlights the physiological role of natural immunity Focuses on the relationship of the neuroendocrine system with natural immunity Brings together the diversity and complexity of natural immune system activity
The Evolution Of Parasitism A Phylogenetic Perspective
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Author :
language : en
Publisher: Elsevier
Release Date : 2003-12-09
The Evolution Of Parasitism A Phylogenetic Perspective written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-12-09 with Medical categories.
Parasitology continues to benefit from taking an evolutionary approach to its study. Tree construction, character-mapping, tree-based evolutionary interpretation, and other developments in molecular and morphological phylogenetics have had a profound influence and have shed new light on the very nature of host-parasite relations and their coevolution. Life cycle complexity, parasite ecology and the origins and evolution of parasitism itself are all underpinned by an understanding of phylogeny. The Evolution of Parasitism - A Phylogenetic Perspective aims to bring together a range of articles that exemplifies the phylogenetic approach as applied to various disciplines within parasitology and as applied by parasitologists. Unified by the use of phylogenies, this book tackles a wide variety of parasite-specific biological problems across a diverse range of taxa. Includes important contributions from leading minds in the field such as Serge Morand, Francisco Ayala and Mark Blaxter, among others Second in the ISI Parasitology List in 2002 with an Impact Factor of 4.818 Series encompasses over 35 years of parasitology coverage
Vertebrate And Invertebrate Respiratory Proteins Lipoproteins And Other Body Fluid Proteins
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Author : Ulrich Hoeger
language : en
Publisher: Springer Nature
Release Date : 2020-03-18
Vertebrate And Invertebrate Respiratory Proteins Lipoproteins And Other Body Fluid Proteins written by Ulrich Hoeger and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-03-18 with Science categories.
This book focuses on respiratory proteins, the broad hemoglobin family, as well as the molluscan and arachnid hemocyanins (and their multifunctional roles). Featuring 20 chapters addressing invertebrate and vertebrate respiratory proteins, lipoproteins and other body fluid proteins, and drawing on the editors’ extensive research in the field, it is a valuable addition to the Subcellular Biochemistry book series. The book covers a wide range of topics, including lipoprotein structure and lipid transport; diverse annelid, crustacean and insect defense proteins; and insect and vertebrate immune complexes. It also discusses a number of other proteins, such as the hemerythrins; serum albumin; serum amyloid A; von Willebrand factor and its interaction with factor VIII; and C-reactive protein. Given its scope, the book appeals to biologists, biomedical scientists and clinicians, as well as advanced undergraduates and postgraduates in these disciplines. Available as a printed book and also as an e-book and e-chapters, the fascinating material included is easily accessible.
Biology Of Fishes
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Author : Quentin Bone
language : en
Publisher: Garland Science
Release Date : 2008-02-01
Biology Of Fishes written by Quentin Bone and has been published by Garland Science this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-01 with Science categories.
The Third Edition of Biology of Fishes is chiefly about fish as remarkably efficient machines for coping with the many problems that life in water entails, and looks at many such special cases. Fishes form the largest group of vertebrates, with around 20,000 known species, and they display a remarkable diversity of size, shape, internal structure and ecology to cope with environments ranging from transient puddles to the abyssal depths of the sea. Biology of Fishes does not try to cover all aspects of fish biology, but focuses on the ingenious ways in which fish have resolved the particular problems that come from living in water, especially body fluid regulation, locomotion, feeding mechanisms, and sensory systems. Enough detail is provided for the reader to be able to go on and use primary research papers. Each chapter has been thoroughly updated and a new chapter on the immune system has been added. This is an ideal textbook for students of fish biology and any of the branches of aquatic biology. Given its skilful combination of breadth and detail, the book also provides a manageable review of fish biology for experienced biologists.