Platelet Transfusion
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Platelet Transfusion
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Author : T.A. Lister
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Platelet Transfusion written by T.A. Lister and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Platelet transfusion has become an integral part of the management of disseminated malignant disease and its role in preventing or controlling haemorrhage due to thrombocytopenia is now without dispute. This monograph contains articles presented at an Inter national Symposium on Platelet Transfusion held in London in July 1978. It is hoped that they provide an up to-date review of the preparation and laboratory function of platelet concentrates in addition to practical advice towards developing an intelligent approach towards their administration. T.A. Lister j.S. Malpas 9 1 Platelet Collection and Quality Control D. Huestis In this chapter I would like to discuss platelet collection tcchniqlll" and q ualit \7 control; the more clinical aspects will be covered by otl)(, l contributors. In the first place it would be prekrable to l()()k .11 platelets from the point ofvin" of the physician lIsingthern - whatlw needs to know so that his usc of platelets will he intelligent and directed by bac kground knowledge of vvhere platelets are found. hcm they arc halYested and stored. and the clinical realities of platekt t ranslilsion. The platelets we transfuse tomorrow walk the streets today. Intelligent donor recruitment and public information carnpaigm about blood donation, and about new systems of blood donation that arc not yet familiar to the general public, need to be broadcast and developed, but are not really a subject of discussion for this meeting. HISTORICAL REVIEW I shall start with an historical perspective on the evolution of platelet transfusion.
Platelet Transfusion Therapy
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Author :
language : en
Publisher:
Release Date : 1987
Platelet Transfusion Therapy written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1987 with Blood categories.
White Cells And Platelets In Blood Transfusion
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Author : C.Th. Smit Sibinga
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
White Cells And Platelets In Blood Transfusion written by C.Th. Smit Sibinga and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
As a clinical discipline blood transfusion encompasses enormous vista, vary ing from biotechnology to molecular biology, from plasma products, cell biology and growth factors to interleukines. Growth of knowledge in this field has been rapid, and expertise is now required to be mastered and renewed in translating these ideas for patient care. Various types of cells could be harvested - progenitor stem cells derived from bone marrow or from circulating blood as a source for transplants; in the hemostatic armoury platelets could be used prophylactically; granulocytes and mononuclear cells are available for treatment of infections or immune modulations. However, their therapeutic use carries potential complications including graft versus host disease and CMV-infection. Prevention of such complications by irradiation and by removal of immunocompetent leukocytes are important issues. Thus, production of such therapeutic materials ought to address the issues at the earliest, to eliminate those problems while adhering to the con cept of high quality; the impact of storing platelets for longer periods by using improved plastic containers or storing almost indefinitely in frozen state should be explored. Rapid progress in cell culture techniques and bio technology have enriched the transfusion medicine armoury with lympho kines, interferons and cell colony growth factors which have great potentials for enhancement of basic knowledge as well as considerable therapeutic applications in patients.
Immunologic Aspects Of Platelet Transfusion
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Author : Leo J. McCarthy
language : en
Publisher: American Association of Blood Banks (AABB)
Release Date : 1985
Immunologic Aspects Of Platelet Transfusion written by Leo J. McCarthy and has been published by American Association of Blood Banks (AABB) this book supported file pdf, txt, epub, kindle and other format this book has been release on 1985 with Blood categories.
Platelet Transfusion Therapy
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Author :
language : en
Publisher:
Release Date : 1986
Platelet Transfusion Therapy written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1986 with Blood categories.
Platelet Transfusion In Severely Ill Patients
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Author : Floor van Baarle
language : en
Publisher:
Release Date : 2024
Platelet Transfusion In Severely Ill Patients written by Floor van Baarle and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024 with categories.
"Severely ill patients, such as those with hematologic malignancy or the critically ill, often suffer from thrombocytopenia and therefore require platelet transfusions either prophylactically or therapeutically. Platelet transfusions are associated with scarcity, high costs and a risk of transfusion-related adverse events. In this thesis we studied the sense and side-effects of platelet transfusion in severely ill patients. In the first part of this thesis we determined the value of prophylactic platelet transfusion before central venous catheter (CVC) placement. We compared different methods of post-procedural bleeding assessment and found that retrospective assessment leads to underreporting of bleeding complications. We also found that differences in definitions and methodology likely influence reported bleeding incidences to a greater extent than differences in patient characteristics. We then compared, in a single-center retrospective cohort, the post-CVC placement bleeding risk of a combined severe thrombocytopenia and coagulopathy versus severe thrombocytopenia alone, and found no difference. Lastly we found, in a multicenter randomized controlled trial (PACER), that prophylactic platelet transfusion before CVC placement in severely ill patients admitted to the hematology ward or intensive care unit, prevents bleeding complications but also comes with higher overall costs. In the second part of this thesis we investigated the relationship between the platelet storage lesion and transfusion efficacy and transfusion-related acute lung injury. During collection and storage of platelet concentrate, platelets undergo biochemical changes collectively referred to as the platelet storage lesion. In a secondary analysis of the PACER trial we found that bone marrow depression, sepsis, disseminated intravascular coagulation and platelet concentrate irradiation, but not storage duration, were negatively with the corrected platelet count increment. In a small randomized trial comparing autologous transfusion of fresh (2 days) and aged (7 days) platelets in healthy male volunteers pre-medicated with lipopolysaccharide to mimic a mild sepsis (DIVA), we found that storage duration did not influence hemostatic measurements, nor the peak concentration of transfused platelets, but the concentration of transfused aged platelets did show a steeper decline reaching peak levels. Also in the DIVA trial, we found no difference in pulmonary inflammation or edema, as determined using bronchoalveolar lavage. Finally, we studied the relationship between platelet concentrate acidity and pulmonary microvascular endothelial inflammation and barrier function in an in vitro model, and found that lower pH is associated with more endothelial inflammation, but not with differences in barrier function."--
Platelet Transfusion Therapy
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Author : Joseph Sweeney
language : en
Publisher: American Association of Blood Banks (AABB)
Release Date : 2013
Platelet Transfusion Therapy written by Joseph Sweeney and has been published by American Association of Blood Banks (AABB) this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013 with categories.
Transfusion Guide For Clinicians
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Author : Kanchan Bhardwaj
language : en
Publisher: JAYPEE BROTHERS PUBLISHERS
Release Date : 2012-12-15
Transfusion Guide For Clinicians written by Kanchan Bhardwaj and has been published by JAYPEE BROTHERS PUBLISHERS this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-15 with Medical categories.
Blood transfusion is an essential part of modern health care. When used correctly; it can save life and improve health. The Transfusion Guide for Clinicians will act as a quick reference for clinicians involved in the transfusion process that needs to make urgent decisions on transfusion. This will help promote rational use of blood. Updates the clinicians about the present scenario of transfusion service in an understandable manner. Guides students and practitioners to adopt advanced methods and techniques on safe blood transfusion so as to work on latest resources and technologies. Empowers clinicians with clinical decision making on Blood Transfusion Therapy and rational use of blood along with managing adverse blood transfusion reactions effectively. Covers complete data of all the clinical aspects of Blood Transfusion Services. Chapters are well structured and are of outstanding educational value. Users will be benefited in transfusion related problems. Text is comprehensive yet lucid manner with short definitions, bullet points and multiple tables. The book has been written for use of the practicing clinical specialists, resident doctors of clinical specialties, ICU specialists, etc.
Platelet Therapy
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Author : Jerard Seghatchian
language : en
Publisher: Elsevier Science Health Science Division
Release Date : 2000
Platelet Therapy written by Jerard Seghatchian and has been published by Elsevier Science Health Science Division this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000 with Medical categories.
Platelet transfusion has evolved through the collaboration of the transfusion service, manufacturer, and the clinician. The major goal for this book is to bring together leading international experts in the field of platelet therapy to provide information on current status and future trends. This multi-author book compiles a wealth of information regarding platelet concentrate production, platelet storage lesion, quality monitoring, bacterial and infectious pathogens contamination and de-contamination, as well as platelet transfusion and alternatives to platelets, platelet immunology and transfusion reactions. Overall this book is viewed as depicting the state of the art for the spectrum of various activities in the field of platelet therapy and research and development. Laboratory, methodological, and clinical aspects are discussed in a simple and practical fashion. Accordingly, this book is of equal interest to laboratory technologists, research and development scientists, and clinicians in various aspects of hemostatic therapy involving platelets and its alternatives. It also appeals to those who wish only an update on new information regarding the field of platelet therapy.
Coagulation And Blood Transfusion
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Author : C.Th. Smit Sibinga
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Coagulation And Blood Transfusion written by C.Th. Smit Sibinga and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
With great pleasure I welcome you to the City of Groningen. In more than one way there is cause for celebration. Today marks the third lustrum of the annual international sympo sium on blood transfusion, organized by the Rode Kruis Bloedbank Groningen-Drenthe. In my opinion it has been a remarkable initiative of the Bloedbank, to start organizing a scientific conference, as it did, in 1976. It meant, among others, that in case of success the initiative would grow to be an annual item on the international congress calen der. It also meant that a possible third lustrum would coincide with the celebration of the 950th anniversary of the City of Groningen. I am happy to note that the initiative has been successful: over the past fourteen years the Rode Kruis Bloedbank Groningen-Drenthe has succeeded in organizing an annual symposium on blood transfusion, with a different theme each year, and with an average attendance of 250 participants from some 26 countries world-wide. The platform created with the special formula of the symposium, for science and industry, has been well balanced and beneficial to both. Mr. Chairman, ladies and gentlemen, I like to compliment the organizers with the success that they have attained. Allow me to men tion the name of just one person, in whom I like to thank everyone who has been involved in creating the annual Bloedbank-symposia: my warm congratulations to Dr. Smit Sibinga and his staff.