Precision Cancer Therapies Volume 1
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Precision Medicine In Cancer Therapy
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Author : Daniel D. Von Hoff
language : en
Publisher: Springer
Release Date : 2019-06-17
Precision Medicine In Cancer Therapy written by Daniel D. Von Hoff and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-06-17 with Medical categories.
This book presents the latest advances in precision medicine in some of the most common cancer types, including hematological, lung and breast malignancies. It also discusses emerging technologies that are making a significant impact on precision medicine in cancer therapy. In addition to describing specific approaches that have already entered clinical practice, the book explores new concepts and tools that are being developed. Precision medicine aims to deliver personalized healthcare tailored to a patient’s genetics, lifestyle and environment, and cancer therapy is one of the areas in which it has flourished in recent years. Documenting the latest advances, this book is of interest to physicians and clinical fellows in the front line of the war on cancer, as well as to basic scientists working in the fields of cancer biology, drug development, biomarker discovery, and biomedical engineering. The contributing authors include translational physicians with first-hand experience in precision patient care.
Advances In Precision Medicine Oncology
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Author : Hilal Arnouk
language : en
Publisher: BoD – Books on Demand
Release Date : 2021-07-21
Advances In Precision Medicine Oncology written by Hilal Arnouk and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-07-21 with Medical categories.
Recent advances in precision medicine and immuno-oncology have led to highly specific and efficacious cancer therapies such as monoclonal antibodies and immune checkpoint inhibitors (ICIs). This book provides an up-to-date overview of advances in the field of immuno-oncology. Chapters cover such topics as ICIs and how they mount a robust immune response against cancer cells as well as the response of ICIs to treatment predictive biomarkers and their potential immune-related adverse events (irAEs). Additionally, the book includes a comprehensive review of the powerful FDA-approved therapeutic agent doxorubicin, highlighting the molecular mechanisms behind doxorubicin’s drug resistance and critical side effects.
Precision Cancer Therapies Volume 2 Immunologic Approaches For The Treatment Of Lymphoid Malignancies
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Author : Owen A. O'Connor
language : en
Publisher: John Wiley & Sons
Release Date : 2024-04-29
Precision Cancer Therapies Volume 2 Immunologic Approaches For The Treatment Of Lymphoid Malignancies written by Owen A. O'Connor and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-04-29 with Medical categories.
Presents timely and authoritative information on the development of precision cancer therapies as applied to hematologic malignancies The Precision Cancer Therapies series focuses on how to understand and translate fundamental basic science into information that can be directly applied to patients to advance care. Each volume of the series integrates the relevant biological concepts and principles necessary for translating this science to practitioners of this science. Precision Cancer Therapies, Volume Two, focuses on sophisticated immunotherapies targeting cancers affecting the blood, bone marrow, and lymph nodes. Edited and authored by the foremost authorities in the field, this comprehensive reference text covers targeting of cell surface receptors, antibody-drug conjugates (ADC), targeting immune checkpoint, targeting macrophages, EBV-directed immunotherapies, tumor-associated antigens (TAA), and chimeric antigen receptor T-cells (CAR-T). Divided into nine sections, Volume Two includes an overview of the history of immunotherapy development in cancer, as well as a concluding section addressing the mechanistic basis and role of immunomodulatory drugs, analytical tools to quantitate immune-mediated effects, and other topics in immunotherapy. Chapters on specific therapeutics or therapeutic classes include a basic explanation of the underlying pathway and target, the pharmacology of the drug/class, relevant preclinical and clinical data, and discussion of clinical management and potential predictive biomarkers of response. This book also: Delivers a definitive, state-of-the-art review of the relevant biology and its importance in the broader context of cancer biology Focuses on agents that mediate cell killing in lymphoma through a variety of immunologic mechanisms Covers FDA-approved drugs and their indications, as well as drugs currently in development Provides information on monotherapy and combination therapy, summary tables of trials, and discussion of toxicity and efficacy Includes boxed sections highlighting major unique points about the information in the chapter Precision Cancer Therapies, Volume Two: Immunologic Approaches for the Treatment of Lymphoid Malignancies, From Concept to Practice is an indispensable resource for medical, scientific, and allied medical professionals, advanced students, and interested general readers with background knowledge in the subject.
Precision Cancer Medicine
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Author : Sameek Roychowdhury
language : en
Publisher: Springer Nature
Release Date : 2020-01-02
Precision Cancer Medicine written by Sameek Roychowdhury and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-01-02 with Medical categories.
Genomic sequencing technologies have augmented the classification of cancer beyond tissue of origin and towards a molecular taxonomy of cancer. This has created opportunities to guide treatment decisions for individual patients with cancer based on their cancer’s unique molecular characteristics, also known as precision cancer medicine. The purpose of this text will be to describe the contribution and need for multiple disciplines working together to deliver precision cancer medicine. This entails a multi-disciplinary approach across fields including molecular pathology, computational biology, clinical oncology, cancer biology, drug development, genetics, immunology, and bioethics. Thus, we have outlined a current text on each of these fields as they work together to overcome various challenges and create opportunities to deliver precision cancer medicine. As trainees and junior faculty enter their respective fields, this text will provide a framework for understanding the role and responsibility for each specialist to contribute to this team science approach.
Targeted Therapies For Solid Tumors
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Author : Antonio Russo
language : en
Publisher: Humana Press
Release Date : 2015-03-11
Targeted Therapies For Solid Tumors written by Antonio Russo and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-03-11 with Medical categories.
This volume provides readers a comprehensive and state-of-the-art overview about the range of applications of targeted therapies for solid tumors. The sections of the book have been structured to review the oncogene addicted tumors, the pharmacology and clinical development of new molecularly targeted agents, the use of biomarkers as prognostic, predictive and surrogate endpoints, and the evaluation of tumor response and specific malignancies treated with targeted agents. The book also covers some of the newest developments in cancer therapy that are not adequately covered by any current available literature. Written by recognized experts in the field, Targeted Therapies for Solid Tumors: A Handbook for Moving Toward New Frontiers in Cancer Treatment provides a unique and valuable resource in the field of molecular oncology, both for those currently in training, and for those already in clinical or research practice.
Precision Cancer Therapies Volume 1
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Author : Stephen M. Ansell
language : en
Publisher: John Wiley & Sons
Release Date : 2023-06-06
Precision Cancer Therapies Volume 1 written by Stephen M. Ansell and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-06-06 with Medical categories.
A Thorough Compilation of the Many Scientific Breakthroughs in the Ongoing Development of Precision Cancer Therapies Related to Lymphoma Targeting Oncogenic Drivers and Signaling Pathways in Lymphoid Malignancies: From Concept to Practice focuses on lymphoma, an area which has seen a remarkable number of breakthroughs in the ongoing development of precision cancer therapies. Each section on a specific biology or class of drugs has an introductory chapter written by an authority in the field, exclusively focused on the science and its relevance to cancer biology. This approach addresses the need for scientists, physicians, and the private sector to understand the broader context of the extraordinary advances that have produced such astonishing advances in the disease. The work primarily focuses on how to understand and translate fundamental principles of basic science into information that can be directly applied to patients – hence the subtitle, From Concept to Practice. To aid in readers’ comprehension, the first page of each chapter contains a box entitled ‘Take Home Points’. This short text will highlight the major unique points about the information contained within the chapter. Some of the key topics addressed in the work are as follows: Biological basis of the lymphoid malignancies: fundamental principles of lymphomagenesis and molecular classification of lymphoid malignancies Targeting programmed cell death: principles for understanding the many types of cell death and promising combinations of drugs targeting apoptosis Targeting the PI3K pathway: understanding the intricacies of this complex biology and precisely how targeted drugs can be leveraged therapeutically Targeting the cancer epigenome: pharmacologic features of drugs targeting the epigenome and future prospects for targeting various aspects of epigenetic control Targeting the tumour proteome: understanding the mechanisms of protein degradation in cancer including both older drugs like proteasome inhibitors, and newer PROTAC based approaches Written primarily for scientists and physicians in both the public and private sectors, Targeting Oncogenic Drivers and Signaling Pathways in Lymphoid Malignancies: From Concept to Practice is a comprehensive reference work for those interested in the growing area of Precision Cancer Therapies. Seamlessly integrating the basic and applied science, this volume will be an indispensable reference for those interested in translating the most important advances in science to innovative novel treatments for patients.
Targeted Therapy In Translational Cancer Research
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Author : Apostolia-Maria Tsimberidou
language : en
Publisher: John Wiley & Sons
Release Date : 2015-10-08
Targeted Therapy In Translational Cancer Research written by Apostolia-Maria Tsimberidou and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-10-08 with Medical categories.
Targeted Therapy in Translational Cancer Research for the Translational Oncology series provides a comprehensive overview of recent developments in our understanding of tumor biology, elucidates the roles of targets and pathways involved in carcinogenesis, and describes current state-of-the-art anticancer therapy, as well as the most promising areas of translational research and targeted therapy. Introduces cutting-edge ‘bench to bedside and back’ breakthroughs which have transformed the diagnosis, prognosis, and treatment of cancer Covers basic principles of targeted therapy, including immunotherapy and the roles of cancer stem cells, the microenvironment, angiogenesis, epigenetics, microRNAs, and functional imaging in precision medicine Summarises major advances in therapeutic management of hematologic malignancies and solid tumors using conventional therapy, targeted therapy, immunotherapy, or novel treatment modalities
Biomarkers In Cancer Detection And Monitoring Of Therapeutics
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Author : Ranbir Chander Sobti
language : en
Publisher: Academic Press
Release Date : 2023-11-24
Biomarkers In Cancer Detection And Monitoring Of Therapeutics written by Ranbir Chander Sobti and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-11-24 with Computers categories.
Molecular Biomarkers in Cancer Detection and Monitoring of Therapeutics, Volume One, Discovery and Technologies discusses how molecular biomarkers are used to determine predisposition, facilitate detection, improve treatment and offer prevention guidelines for different cancer types. This first volume in the series focuses on techniques and approaches recently developed to assist in the decision of which biomarker to use for specific conditions. Topics covered include circulating tumor cells and circulating tumor DNA, exomes, tumor microenvironment, gene editing, artificial intelligence and robotics. In addition, the book discusses the development and applications of organoids and precision medicine.This book will be a valuable resource for cancer researchers, oncologists, graduate students and members of the biomedical field who are interested in the potential of biomarkers in cancer research. Provides up-to-date information on current molecular biomarkers research for cancer Presents basic research aspects and novel technologies applied in the discovery of new biomarkers Discusses several technologies, including artificial intelligence, robotics, data mining, gene editing, omics and their applicability for specific cancer types
Precision Medicine In Cancers And Non Communicable Diseases
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Author : Debmalya Barh
language : en
Publisher:
Release Date : 2018-09-03
Precision Medicine In Cancers And Non Communicable Diseases written by Debmalya Barh and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-09-03 with HEALTH & FITNESS categories.
The availability of human genome, large amount of data on individual genetic variations, environmental interactions, influence of lifestyle, and cutting-edge tools and technologies for big-data analysis have led to the era of clinical practice of "Precision Medicine". This book aims to provide a readily available resource on all the important developments achieved so far in the field of oncology. All recent developments have been explained along with epidemiology, technologies and approaches to manage the included diseases. Therefore, readers will get the up to date information on the next-generation approach in tackling all kinds of cancer. Key Features * Presents the latest trend of cancer management based on precision/predictive medicine approach * Reviews the latest and up to date literature in the field of Precision Medicine * Highlights the next generation approach in tackling malignant diseases * Discusses how a life-threatening disease like cancer can be managed with the help of Precision Medicine * Encapsulates a global prospective
Precision Medicine In Oncology An Issue Of Surgical Oncology Clinics Of North America
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Author : Vijay P. Khatri
language : en
Publisher: Elsevier
Release Date : 2019-12-04
Precision Medicine In Oncology An Issue Of Surgical Oncology Clinics Of North America written by Vijay P. Khatri and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-12-04 with categories.
This issue of Surgical Oncology Clinics of North America, guest edited by Drs. Vijay Khatri and Nicholas J. Petrelli, is devoted to Precision Medicine in Surgical Oncology. Drs. Khatri and Petrelli have assembled expert authors to review the following topics: Gene Expression Profiling in Melanoma; Precision Medicine in Lung Cancer; Precision Medicine in Colon Cancer; Immunotherapy in the Treatment of Melanoma; Genomics and History of Precision Medicine; Cancer Genomics and Precision Medicine in 21st Century; Precision Medicine in Breast Cancer; Precision Medicine in Pediatrics; Establishing a Precision Cancer Medicine Program; much more!