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Pulmonary Deposition And Retention Of Inhaled Aerosols


Pulmonary Deposition And Retention Of Inhaled Aerosols
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Pulmonary Deposition And Retention Of Inhaled Aerosols


Pulmonary Deposition And Retention Of Inhaled Aerosols
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Author : Theodore F. Hatch
language : en
Publisher: Elsevier
Release Date : 2013-09-12

Pulmonary Deposition And Retention Of Inhaled Aerosols written by Theodore F. Hatch and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-09-12 with Science categories.


Pulmonary Deposition and Retention of Inhaled Aerosols is concerned with the respiratory deposition and retention of inhaled aerosols, starting with initial intake and concluding with events that precede pathological tissue response, drawing equally upon both the physical and biological aspects of the subject. The book opens with an introductory chapter on the relationship between the dose of an inhaled aerosol and the kind and degree of response, and classification of particulate substances. This is followed by separate chapters on pulmonary deposition and retention of inhaled aerosols; the factors that influence disease risks associated with atmospheric exposure to aerosols; and measurement of aerosol composition and concentration. It is hoped that the book will help the specialists from both sides as well as technical and administrative personnel to acquire a common understanding of the important intermediate factors that operate between the outside dusty atmosphere and the internal tissue damage and disease—factors that may operate to make one exposure dangerous to life and another altogether innocuous.



Extrapolation Of Dosimetric Relationships For Inhaled Particles And Gases


Extrapolation Of Dosimetric Relationships For Inhaled Particles And Gases
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Author : James D. Crapo
language : en
Publisher:
Release Date : 1989

Extrapolation Of Dosimetric Relationships For Inhaled Particles And Gases written by James D. Crapo and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1989 with Medical categories.


Extrapolation Modeling, Advancements and Research Issues in Lung Dosimetry; Lung Structure, Function Relationships; Species Differences in Airway Cell Distribution and Morphology; Alternative Methods to Evaluate Species Differences in Upper Airway Structure, Function; Preparation of Rat Nasal Airway Casts and Their Application to Studies of Nasal Airflow; Age Related Morphometric Analysis of Human Lung Casts; Anatomical Modeling of Microdosimetry of Inhaled Particles and Gases in the Lung; Experimental Dosimetry; Particle Deposition at the Alveolar Duct Bifurcations; Effects of Airway Branch Angle, Branch Point Number, and Gravity on Particle Deposition and Retention; Regional Deposition of Inhaled Particulates in Conducting Airways and Lung Segments; The Physical Properties of Mainstream Cigarette Smoke and Their Relationship to Deposition in the Respiratory Tract; Localization of 14C Dotriacontane Labeled Cigarette Smoke Particulate in the Dog Lung; Human Lung Clearance Following Bolus Inhalation of Radioaerosols; Effects of Ventilatory Patterns and Pre-existing Disease on Deposition of Inhaled Particles in Animals; Nasopharyngeal Uptake of Ozone in Humans and Animals; New Methods; Regional Dosimetry of Inhaled Particles Using SPECT; Dual Laser Doppler System for Real Time, Simultaneous Characterization of Aerosols by Size and Concentration; Dosimetry of Inhaled Particles by Means of Light Scattering; Modeling Approaches; Issues That Must Be Addressed When Constructing Anatomical Models of the Developing Lung; Significances of the Variability of Tracheobronchial Airway Paths and Their Air Flow Rates to Dosimetry Model Predictions of the Absorption of Gases; Predicting Respiratory Tract Clearance in Man; The Role of Particle Hygroscopicity in Aerosol Therapy and Inhalation Toxicology; Age-Dependent Lung Dosimetry of Radon Progeny; Deposition and Retention Modeling of Inhaled Cadmium in Rat and Human Lung, An Example for Extrapolation of Effects and Risk Estimation.



Aerosols And The Lung


Aerosols And The Lung
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Author : Stewart W. Clarke
language : en
Publisher: Elsevier
Release Date : 2015-08-11

Aerosols And The Lung written by Stewart W. Clarke and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-08-11 with Medical categories.


Aerosols and the Lung covers all aspects of aerosols and the lung, including the use of aerosol in clinical medicine. This volume was developed from the editors' longstanding interest in lung defenses coupled with the radioaerosol technique of assessing their efficiency. This book is organized into 11 chapters. The coverage of these chapters include the physical properties of aerosol required to evaluate their inhalation into the lung, production of aerosol that is suitable for inhalation, determination of aerosol deposition in the lungs and the assessment of lung clearance. This book also highlights the importance of radioaerosols in estimating airway calibre, in detecting airway disease and in ventilation imaging. This book will be of interest to medical students and professionals, particularly those dealing with studies of the human lungs and aerosols.



Drug Delivery To The Lung


Drug Delivery To The Lung
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Author : Hans Bisgaard
language : en
Publisher: CRC Press
Release Date : 2001-10-02

Drug Delivery To The Lung written by Hans Bisgaard and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-10-02 with Medical categories.


This book focuses on the aerosol treatment of lung diseases, recent improvements in the understanding of proper dosage, and major innovations in device technology applied to clinical practice. Examines the behavior of inspired spherical particles in the respiratory tract!Featuring over 1300 references, drawings, tables, and photographs.



Inhaled Particles


Inhaled Particles
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Author : Chiu-sen Wang
language : en
Publisher: Elsevier
Release Date : 2005-01-20

Inhaled Particles written by Chiu-sen Wang and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-01-20 with Technology & Engineering categories.


Inhaled Particles integrates all that is known about inhaled particles in a unified treatment. It aims to provide a scientific framework essential to a reasonable understanding of inhaled particles. The emphasis is placed on demonstrating the key roles of lung morphology on airflow and particle transport as well as identifying physical and biological factors that influence deposition. Special attention is paid to maintaining consistency of treatment and a balance between theoretical modeling and experimental measurements. The book covers all important aspects of inhaled particles including inhalability, aerosol dispersion, particle deposition, and clearance. It reviews concisely the basic background of lung morphology, respiratory physiology, aerodynamics, and aerosol science pertinent to the subject. Essential aspects of health effects and applications are also included. An easy-to-read, self contained introduction to the field An excellent source of updated research information Useful for students and professionals in aerosol science, environmental health science, occupational hygiene, health physics and biomedical engineering



Inhaled Particles Vi


Inhaled Particles Vi
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Author : J. Dodgson
language : en
Publisher: Elsevier
Release Date : 2013-09-17

Inhaled Particles Vi written by J. Dodgson and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-09-17 with Medical categories.


Inhaled Particles VI contains the proceedings of an international symposium and workshop on lung dosimetry, organized by the British Occupational Hygiene Society in cooperation with the Commission of the European Communities and held at Cambridge on September 2-6, 1985. The symposium presents results of research on the entry, destiny, and effects of respired particles, with emphasis on mechanisms and dose-response relationships. This book contains, in three separate parts, 84 papers from the symposium, 34 workshop papers, and 20 poster presentations. Parts 1 and 2 are further divided into sections. Section 1 presents several papers concerning the influence of breathing pattern and activity on regional deposition of inhaled particles. Section 2 shows comparative studies of aerosol deposition in experimental animals and humans. Subsequent sections explore the mineral content of lungs to differing exposures; biological effects of dusts; hazard parameters; dust measurement; exposure of workers to vermiculite and attapulgite; effects of dust exposure in the coal mining industry; and effects of silica dust exposure. Other topics of significance include toxicity of artificial mineral fibers and utility of magnetopneumography as a non-invasive investigational test.



Aerosols And The Human Lung An Introduction


Aerosols And The Human Lung An Introduction
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Author : Chantal J Darquenne
language : en
Publisher: World Scientific
Release Date : 2020-03-10

Aerosols And The Human Lung An Introduction written by Chantal J Darquenne and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-03-10 with Medical categories.


This book provides a comprehensive overview of the field of aerosol science related to particle inhalation and its effect on the lung, predominately in humans. It covers the basics of aerosol behavior, transport, deposition, clearance, and effects of aerosols, both environmental and therapeutic. Aimed at the researcher entering the field of aerosol inhalation it provides a valuable introductory resource in an accessible format.



The Respiratory Tract Deposition Model Proposed By The Icrp Task Group


The Respiratory Tract Deposition Model Proposed By The Icrp Task Group
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Author :
language : en
Publisher:
Release Date : 1990

The Respiratory Tract Deposition Model Proposed By The Icrp Task Group written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1990 with categories.


The Task Group has developed a new model of the deposition of inhaled aerosols in each anatomical region of the respiratory tract. The model is used to evaluate the fraction of airborne activity that is deposited in respiratory regions having distinct retention characteristics and clearance pathways: the anterior nares, the extrathoracic airways of the naso- and oropharynx and larynx, the bronchi, the bronchioles, and the alveolated airways of the lung. Drawn from experimental data on total and regional deposition in human subjects, the model is based on extrapolation of these data by means of a detailed theoretical model of aerosol transport and deposition within the lung. The Task Group model applies to all practical conditions, and for aerosol particles and vapors from atomic size up to very coarse aerosols with an activity median aerodynamic diameter of 100 [mu]m. The model is designed to predict regional deposition in different subjects, including adults of either sex, children of various ages, and infants, and also to account for anatomical differences among Caucasian and non-Caucasian subjects. The Task Group model represents aerosol inhalability and regional deposition in different subjects by algebraic expressions of aerosol size, breathing rates, standard lung volumes, and scaling factors for airway dimensions. 35 refs., 13 figs., 2 tabs.



Inhaled Particles And Vapours


Inhaled Particles And Vapours
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Author : C. N. Davies
language : en
Publisher: Elsevier
Release Date : 2013-09-17

Inhaled Particles And Vapours written by C. N. Davies and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-09-17 with Medical categories.


Inhaled Particles and Vapors covers the proceedings of an International Symposium by the same title on September 28 – October 1, 1965, organized by the British Occupational Hygiene Society. This book is organized into seven sections encompassing 48 chapters. Section I reviews the anatomy and physiology of human lung. Section II describes the pulmonary response to dust in terms of airway changes and reactions to silica. Sections III and IV deal with lung clearance in animals, the retention, penetration, and elimination of inhaled dusts, and lung deposition and clearance in human. Section V emphasizes the sources of dust inhaled by the human lungs, while Section VI discusses the relationship between pneumonoconiosis and dust exposure. Section VII presents the results of the investigations of dust exposure. This book will prove useful to pulmonologists, toxicologists, and workers in the field of occupational health.



Pulmonary Depostion And Retention Of Inhaled Aerosols


Pulmonary Depostion And Retention Of Inhaled Aerosols
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Author : Theodore Frederick Hatch
language : en
Publisher:
Release Date : 1964

Pulmonary Depostion And Retention Of Inhaled Aerosols written by Theodore Frederick Hatch and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1964 with categories.