Recomb 98

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Recomb 98

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Author :
language : en
Publisher:
Release Date : 1998

Recomb 98 written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998 with categories.

Selected Papers From Recomb 98

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Author : RECOMB
language : en
Publisher:
Release Date : 1998

Selected Papers From Recomb 98 written by RECOMB and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998 with categories.

Recomb 98

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Author : Sorin Istrail
language : en
Publisher: Association for Computing Machinery (ACM)
Release Date : 1998

Recomb 98 written by Sorin Istrail and has been published by Association for Computing Machinery (ACM) this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998 with Computer simulation categories.

Recomb 2003

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Author : Webb Miller
language : en
Publisher:
Release Date : 2003

Recomb 2003 written by Webb Miller and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003 with Computer science categories.

We study haplotype reconstruction under the Mendelian law of inheritance and the minimum recombination principleon pedigree data. We prove that the problem of finding a mini-mum-recombinant haplotype configuration (MRHC) is in general NP-hard. This is the first complexity result concerning the problem to our knowledge. An iterative algorithm based on blocks of consecutive resolved marker loci (called block-extension) is proposed. It is very efficient and can be used for large pedigrees with a large number of markers, especially for those data sets requiring few recombinants (or recombination events). A polynomial-time exact algorithm for haplotype reconstruction without recombinants is also presented. This algorithm first identifies all the necessary constraints based on the Mendelian law and the zero recombinant assumption, and represents them using a system of linear equations over the cyclic group Z2. By using a simple method based on Gaussian elimination, we could obtain all possible feasible haplotype configurations. We have tested the block-extension algorithm on simulated data generated on three pedigree structures. The results show that the algorithm performs very well on both multi-allelic and biallelic data, especially when the number of recombinants is small.

Proceedings Of The Sixth Annual International Conference On Computational Biology

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Author : Gene Myers
language : en
Publisher:
Release Date : 2002

Proceedings Of The Sixth Annual International Conference On Computational Biology written by Gene Myers and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Computer science categories.

Algorithms Esa 98

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Author : Gianfranco Bilardi
language : en
Publisher: Lecture Notes in Computer Science
Release Date : 1998-07-29

Algorithms Esa 98 written by Gianfranco Bilardi and has been published by Lecture Notes in Computer Science this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998-07-29 with Computers categories.

This book constitutes the refereed proceedings of the 6th Annual European Symposium on Algorithms, ESA'97, held in Venice, Italy, in August 1998. The 40 revised full papers presented together with two invited contributions were carefully reviewed and selected from a total of 131 submissions. The book is divided into sections on data structures, strings and biology, numerical algorithms, geometry, randomized and online algorithms, parallel and distributed algorithms, graph algorithms, and optimization.

Theoretical Computer Science Exploring New Frontiers Of Theoretical Informatics

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Author : Jan Leeuwen
language : en
Publisher: Springer Science & Business Media
Release Date : 2000-07-26

Theoretical Computer Science Exploring New Frontiers Of Theoretical Informatics written by Jan Leeuwen and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-07-26 with Computers categories.

This book constitutes the refereed proceedings of the International Conference IFIP TCS 2000 held in Sendai, Japan in August 2000. The 32 revised full papers presented together with nine invited contributions were carefully reviewed and selected from a total of 70 submissions. The papers are organized in two tracks on algorithms, complexity, and models of computation and on logics, semantics, specification, and verification. The book is devoted to exploring new frontiers of theoretical informatics and addresses all current topics in theoretical computer science.

Proceedings Of The Annual International Conference On Computational Molecular Biology

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Author :
language : en
Publisher:
Release Date : 1998

Proceedings Of The Annual International Conference On Computational Molecular Biology written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998 with Molecular biology categories.

Recombinant Dna Technical Bulletin

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Author :
language : en
Publisher:
Release Date : 1981

Recombinant Dna Technical Bulletin written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1981 with Genetic engineering categories.

V D J Recombination

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Author : Pierre Ferrier
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-12-24

V D J Recombination written by Pierre Ferrier and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-12-24 with Medical categories.

v(D)J recombination: for the community of immunologists and developmental biologists, the molecular route by which B and T lymphocytes acquire their unique function of affording adaptive immunity. Yet, for many-from experienced scientists to trainees-it represents a (rather too) sophisticated process whose true insight is excessively demanding. However, when not simplyconsidered as a private ground for a few aficionados, it can be seen as a way of understanding how maturelympho cytes carry on their basic functions. For the group of aficionados-which includes this editor-it is an elegant paradigm featuring many fascinating evolutionary achievements of which the biological world alone has the secret. These include a subtle biochemical principle most likelyhijacked some 470 million years ago from an ancestral gene invader and since then cleverly adapted by jawed vertebrates to precisely cleave and rearrange their antigen receptor (Ig andTCR)loci. This invader would itself have assigned the services of the nonhomologous end joining (NHEJ) DNArepair machinery as well as various DNApolymerases or transferases to work in concert with developmental clues in lymphoid cell lineages to generate an immune repertoire and efficient host surveillance while avoiding autoimmunity. Recently, important new refinements in these systems have emerged, continuing to challenge ourknowledge andbeliefs. These arejust thetopics covered by the senior authors-all established leaders in this field-and their colleagues, whilst writing the various chapters in V(D)J Recombination.