Recurrent Implantation Failure
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Recurrent Implantation Failure
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Author : Efstratios M. Kolibianakis
language : en
Publisher: CRC Press
Release Date : 2019-07-30
Recurrent Implantation Failure written by Efstratios M. Kolibianakis and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-07-30 with Medical categories.
Implantation is a complex phenomenon, still not thoroughly understood, involving the embryo and the endometrium. Successful implantation is considered to stem from an efficient combination of various embryo and/or maternal factors. Repeated failure of any of these factors or of their combination might decrease the chance of implantation and eventually lead to recurrent implantation failure. Despite technological advances, only about a quarter of In Vitro Fertilization procedures will result in live birth, leading many couples to experience multiple failures. This text from international experts explores the various factors at play and offers a helpful summary of the state of knowledge to help guide clinicians in their management of this complex and important problem. Contents: What is Recurrent Implantation Failure? * The psychosocial aspects of recurrent implantation failure * The role of life-style factors in RIF * Endocrine causes of recurrent implantation failure * Congenital uterine anomalies and recurrent implantation failure * Immunological causes of recurrent implantation failure * Acquired uterine conditions, reproductive surgery, and RIF? * Thrombophilia: diagnosis and management in women with recurrent implantation failure * Andrological causes of RIF * Diagnostic evaluation of RIF? (Modalities and algorithm) * Optimizing embryo culture for RIF? * Optimizing endometrial receptivity for patients with recurrent implantation failure: The role of progesterone on the day of triggering final oocyte maturation * Is there a role of follicular phase LH and E2 on the day of triggering final oocyte maturation for embryo implantation? * Manipulating the endometrium: Can RIF be managed by inducing endometrial inflammation or by the use of novel research therapies * The embryo in RIF: Genetic selection and strategies for improving its implantation potential * Is oocyte donation efficient in patients with RIF? * Sperm donation and RIF? * Optimizing embryo transfer technique for RIF management * Proposed management of patients with recurrent implantation failure and directions for future research * When should patients abandon treatment?
Recurrent Implantation Failure
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Author : Jason M. Franasiak
language : en
Publisher: Springer
Release Date : 2018-04-03
Recurrent Implantation Failure written by Jason M. Franasiak and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-04-03 with Health & Fitness categories.
This unique text discusses the wide range of causes and pathophysiologic conditions contributing to recurrent implantation failure (RIF) and the current treatment approaches to best approach this challenging patient population. Beginning with a presentation of the mechanism of normal implantation, the physiologic synchrony between embryo and endometrium, and the roles of both gametes and embryos in RIF, the book then examines the various genetic, immune and environmental factors involved. Abnormalities of the hematologic and endocrine system, as well as those of the anatomy and microbiome, are described in detail. Last but no less important, the psychological stress and treatment of patients experiencing RIF is discussed. Assisted reproductive technology (ART) success has increased substantially over the past three decades. However, despite these advances, recurrent implantation failure is still a common issue confronting patients and clinicians, and RIF represents one of the greatest challenges in ART and remains a source of frustration and disappointment for patients, clinicians, and researchers involved in the process. Providing an in-depth investigation into the pathophysiology and biological mechanisms of RIF and its clinical management, this will be an excellent resource for reproductive endocrinologists and infertility specialists.
Recurrent Implantation Failure
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Author : Mariana Fonseca Roller Barcelos
language : en
Publisher:
Release Date : 2018
Recurrent Implantation Failure written by Mariana Fonseca Roller Barcelos and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018 with Electronic books categories.
Recurrent implantation failure (RIF) is one of the great challenges of current reproductive medicine. The term refers to the failure of repeated transfers of embryos of good morphological quality. Embryo implantation is a crucial moment in in vitro fertilization (IVF) treatments. A successful pregnancy depends on a synchronized interaction between a good quality embryo and a receptive endometrium. Its failure may be a consequence of embryo quality, anatomical or immunological factors. The anatomic causes constitute an important factor for RIF, although they are usually manageable. Fibroids, polyps and adhesions that develop after a surgical procedure or infection can hamper the embryo - endometrium attachment process. In addition, Mullerian abnormalities and hydrosalpinx can cause a negative impact on implantation rates and should also be taken into account in patients with RIF. In this chapter, we will address the main anatomical causes that may impact the implantation rates of patients undergoing IVF, as well as recommendations on management and its treatment.
Recurrent Implantation Failure The Big Challenge
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Author : Sophia Abdallah
language : en
Publisher: LAP Lambert Academic Publishing
Release Date : 2012
Recurrent Implantation Failure The Big Challenge written by Sophia Abdallah and has been published by LAP Lambert Academic Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with categories.
Infertility is an increasing problem in many societies. Despite advances in evaluation and treatment achieved in this field, success rate of assisted reproduction is still below 30%. Implantation failure becomes a cause of considerable frustration and disappointment for clinician, embryologist and couple concerned. This book provides an update overview of this condition. It exposes the most recent knowledge concerning physiological and pathological aspects of implantation. It revives the concept of dialogue between embryologist and infertility specialist which should reflects the harmony between embryo and endometrium.This volume also shares evaluation and treatment strategies cited in the literature .It updates the knowledge of specialists concerning this intriguing topic and will be very helpful in dealing with with this condition.
Immunology Of Recurrent Pregnancy Loss And Implantation Failure
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Author : Joanna Kwak-Kim
language : en
Publisher: Elsevier
Release Date : 2022-07-07
Immunology Of Recurrent Pregnancy Loss And Implantation Failure written by Joanna Kwak-Kim and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-07-07 with Medical categories.
Immunology of Recurrent Pregnancy Loss provides doctors and immunologists with the information they need to help couples who experience recurrent pregnancy losses. Sections cover unexplained infertility, repeated in vitro fertilization, embryo transfer failures, history of second or third trimester pregnancy losses of unknown cause, or pregnancy with a history of or active autoimmune and/or alloimmune disease. Reproductive failure (RF), including recurrent pregnancy losses (RPL) and repeated implantation failures (RIF) is rather a syndrome than a disease caused by multiple etiologies, such as anatomical, endocrine, genetic, infectious, immunological, thrombotic and unexplained etiologies, hence this book strives to present the latest information. In 27 chapters, divided in 5 sections, the book introduces the current update of reproductive immunology topics in RF and provides systematic diagnostic guidelines, systemic and immune etiologies and therapeutic approaches. Provides detailed immunological background for understanding the etiology and management of reproduction failure Evaluates various immunological factors involved in the pathogenesis and management of reproduction failure Gives insights into various immunological and therapeutic approaches for reproduction failure
Treatment Strategy For Unexplained Infertility And Recurrent Miscarriage
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Author : Keiji Kuroda
language : en
Publisher: Springer
Release Date : 2018-06-15
Treatment Strategy For Unexplained Infertility And Recurrent Miscarriage written by Keiji Kuroda and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-06-15 with Medical categories.
This book offers a highly informative guide to treating unexplained infertility and recurrent miscarriage (RM). In particular, it provides detailed treatment strategies for infertility or RM derived from uterine circumstance such as chronic endometritis and perturbation of endometrial decidualization, as well as maternal immunological rejection of an embryo as semi-allograft. Unexplained infertility refers to those types that cannot be detected by the general screening test. The causes are sometimes detected in the course of treatment with assisted reproductive technology including IVF. However, some unexplained infertility is intractable even after intracytoplasmic sperm injection or repeated implantation of morphologically suitable embryos. Patients with unexplained RM also have a high likelihood of undetectable risk factors of miscarriage. As a result, gynecologists often repeatedly provide these couples with general treatments for infertility and miscarriage or even discontinue treatment because they cannot detect the reason, which places serious financial, physical and mental burdens on the couples affected. This book offers gynecologists essential insights into the pathological condition of unexplained infertility and RM, equipping them to identify it, explain it to patients, and consider further examinations and more aggressive fertility treatments.
Immunology Of Recurrent Pregnancy Loss And Implantation Failure
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Author : Joanna Kwak-Kim
language : en
Publisher: Academic Press
Release Date : 2022-07-03
Immunology Of Recurrent Pregnancy Loss And Implantation Failure written by Joanna Kwak-Kim and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-07-03 with Medical categories.
Immunology of Recurrent Pregnancy Loss provides doctors and immunologists with the information they need to help couples who experience recurrent pregnancy losses. Sections cover unexplained infertility, repeated in vitro fertilization, embryo transfer failures, history of second or third trimester pregnancy losses of unknown cause, or pregnancy with a history of or active autoimmune and/or alloimmune disease. Reproductive failure (RF), including recurrent pregnancy losses (RPL) and repeated implantation failures (RIF) is rather a syndrome than a disease caused by multiple etiologies, such as anatomical, endocrine, genetic, infectious, immunological, thrombotic and unexplained etiologies, hence this book strives to present the latest information. In 27 chapters, divided in 5 sections, the book introduces the current update of reproductive immunology topics in RF and provides systematic diagnostic guidelines, systemic and immune etiologies and therapeutic approaches. Provides detailed immunological background for understanding the etiology and management of reproduction failure Evaluates various immunological factors involved in the pathogenesis and management of reproduction failure Gives insights into various immunological and therapeutic approaches for reproduction failure
Clinical Management Of Infertility
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Author : Joseph G. Schenker
language : en
Publisher: Springer Nature
Release Date : 2021-08-01
Clinical Management Of Infertility written by Joseph G. Schenker and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-08-01 with Health & Fitness categories.
This new volume in the Reproductive Medicine for Clinicians series focuses on the practical clinical impact of problems linked to infertility, discussing topics such as luteal support in ART cycles, ovulation induction using pulsatile administration of GnRH, how to deal with the metabolic changes in PCOS, treatment to restore fertility in endometriosis and how to improve implantation, which are common aspects of daily clinical practice. It also addresses significant novel areas like the biological clock in human reproduction, reproduction at advanced parental age and medical and social egg freezing, offering valuable insights for patients and their doctors. Further, the book covers various areas of growing importance, such as how to access the uterine cavity; the future of imaging in reproduction; non-invasive prenatal testing; ART and male infertility; as well as breast cancer and fertility preservation. Last but not least, it examines the medical, ethical and legal aspects of a number of challenges for current and future reproductive medicine, including uterine transplantation and human genetic modification. Bringing together updates on some of the most important problems in reproductive medicine and also covering ethical and legal bases, this book offers an overview of potential treatments for infertility. As such, it is a valuable resource for gynecologists, obstetricians, endocrinologists and all specialists dealing with reproductive health.
Reasons And Mechanisms Of Recurrent Failed Implantation In Ivf
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Author : Juris Erenpreiss
language : en
Publisher:
Release Date : 2022
Reasons And Mechanisms Of Recurrent Failed Implantation In Ivf written by Juris Erenpreiss and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022 with Electronic books categories.
Recurrent pregnancy loss (RPL) and recurrent implantation failure (RIF) are serious problems in IVF and ICSI cycles. Different factors are showed to be responsible for these clinical challenges ,Äì such as paternal, maternal, embryonic, immunological, infectious, hormonal, and others. In this chapter we have tried to review the available data on reasons for the RIF, and systematize them into: 1) uterine factors; 2) embryo factors; 3) immunological factors; 4) other factors. Interplay between all these factors play a role in RIF, and further investigations are needed to elucidate their significance and interactions ,Äì in order to elaborate more definite suggestions or guidelines for the clinicians dealing with artificial reproductive techniques and facing RPL and RIF.
A Comparative Study Of Women With Recurrent Implantation Failure And Recurrent Miscarriage
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Author :
language : en
Publisher:
Release Date : 2012
A Comparative Study Of Women With Recurrent Implantation Failure And Recurrent Miscarriage written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with categories.