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Response And Survival Of Breast Cancer Intrinsic Subtypes Following Multi Agent Neoadjuvant Chemotherapy


Response And Survival Of Breast Cancer Intrinsic Subtypes Following Multi Agent Neoadjuvant Chemotherapy
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Response And Survival Of Breast Cancer Intrinsic Subtypes Following Multi Agent Neoadjuvant Chemotherapy


Response And Survival Of Breast Cancer Intrinsic Subtypes Following Multi Agent Neoadjuvant Chemotherapy
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Author : Taipei Taipei Press
language : en
Publisher:
Release Date : 2015-12-19

Response And Survival Of Breast Cancer Intrinsic Subtypes Following Multi Agent Neoadjuvant Chemotherapy written by Taipei Taipei Press and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-12-19 with categories.


Predicting treatment benefit and/or outcome before any therapeutic intervention has taken place would be clinically very useful. Herein, we evaluate the ability of the intrinsic subtypes and the risk of relapse score at diagnosis to predict survival and response following neoadjuvant chemotherapy. In addition, we evaluated the ability of the Claudin-low and 7-TNBCtype classifications to predict response within triple-negative breast cancer (TNBC).



Chimioth Rapie N O Adjuvante


Chimioth Rapie N O Adjuvante
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Author : Claude Jacquillat
language : fr
Publisher:
Release Date : 1988

Chimioth Rapie N O Adjuvante written by Claude Jacquillat and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988 with Adjuvants, Immunological categories.




Preoperative Neoadjuvant Chemotherapy


Preoperative Neoadjuvant Chemotherapy
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Author : Joseph Ragaz
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Preoperative Neoadjuvant Chemotherapy written by Joseph Ragaz and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


Despite recent advances in adjuvant therapies of cancer, the regi mens of postoperative adjuvant chemotherapy treatment which are presently available fail to cure the majority of cancer patients. Pre operative (neoadjuvant) chemotherapy represents a new approach in drug scheduling, based on sound theoretical, pharmacokinetic, and experimental principles. The preoperative timing of chemotherapy before definitive sur gery is not a minor change in the therapy of cancer. To be successful, large numbers of practitioners and their patients must participate. Substantial alterations of many aspects of the present management of cancer will have to follow. Therefore, before such therapy can be fully and routinely implemented, results of the novel treatment and its rationale have to be carefully evaluated. In preoperative treatment, other features will likely gain impor tance. For the first time, clinicians have a chance to follow the in vivo response of the tumor exposed to preoperative chemotherapy. The subsequent histological assessment of the tumor sample may likely become an important prognostic guide, permitting more re fined individual approaches to the planning of postoperative adju vant treatment. The value of such a treatment strategy can already be appreciated in the clinical setting, as seen from the therapy of osteosarcoma. Furthermore, preoperative chemotherapy might render previously inoperable tumors operable and hence resectable with a curative intention. The preoperative reduction of tumor bulk may also effectively decrease the need for more radical operations, permitting a more uniform adoption of conservative surgery.



Modern European And Chinese Contract Law


Modern European And Chinese Contract Law
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Author : Junwei Fu
language : en
Publisher: Kluwer Law International B.V.
Release Date : 2011-01-01

Modern European And Chinese Contract Law written by Junwei Fu and has been published by Kluwer Law International B.V. this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-01-01 with Law categories.


This comparative study of European and Chinese contract law opens a clear and practical way to identify and understand the differences between the two legal regimes. The author offers a detailed doctrinal comparison of the two systems of contract, focusing on the following fundamental elements: * the importance of socio-economic valuation in Chinese contract law; * the role of judicial interpretation; * pre-contractual liability - penalties for bad faith, disclosure versus concealment; * validity - mistake, fraud, threats, unfair bargaining power; * adaptation and termination - effect of registration and approval rules; * mandatory rules - good faith and fair dealing, the public interest; and * direct application of constitutional law to contracts. The book's special power lies in its extraordinarily thorough comparison of doctrines underlying specific provisions of such instruments as the Contract Law of the People's Republic of China (CLC), the General Principles of the Civil Law of the People's Republic of China (GPCL), the Principles of European Contract Law (PECL), and the Draft Common Frame of Reference (DCFR), as well as analysis of judicial cases.



Management Of Early Stage Breast Cancer


Management Of Early Stage Breast Cancer
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Author : Beena Kunheri
language : en
Publisher: Springer Nature
Release Date : 2020-10-01

Management Of Early Stage Breast Cancer written by Beena Kunheri and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-10-01 with Medical categories.


Breast cancer, its causes, early detection and treatment have received considerable attention, since this widespread disease is one of the most important health concerns for women. This book provides a comprehensive overview of the diagnostic and therapeutic aspects of the management of early-stage breast cancer, including essential information on basic topics like pathology, and radiology, as well as the latest developments. Further, it discusses all aspects of surgical care, chemotherapy and radiation therapy, together with the controversies and current management guidelines. Helping readers acquire a deep, holistic understanding of the topic, the book is a valuable resource for practitioners and postgraduate students in the field of gynecologic oncology. Moreover, it is a useful aid to decision-making in day-to-day practice for oncologists, residents, fellows and experienced practitioners.



Who Classification Of Tumours Of The Breast


Who Classification Of Tumours Of The Breast
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Author : Sunil R. Lakhani
language : en
Publisher: World Health Organization
Release Date : 2012

Who Classification Of Tumours Of The Breast written by Sunil R. Lakhani and has been published by World Health Organization this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with Medical categories.


WHO Classification of Tumours of the Breast is the fourth volume of the WHO series on histological and genetic typing of human tumours. This authoritative, concise reference book provides an international standard for oncologists and pathologists and will serve as an indispensable guide for use in the design of studies monitoring response to therapy and clinical outcome. Diagnostic criteria, pathological features, and associated genetic alterations are described in a strictly disease-oriented manner. Sections on all recognized neoplasms and their variants include new ICD-O codes, epidemiology, clinical features, macroscopy, pathology, genetics, and prognosis and predictive factors. The book, prepared by 90 authors from 24 countries, contains more than 340 colour photographs, tables and figures, and more than 1600 references.



Breast Cancer


Breast Cancer
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Author : Suresh Chander Sharma
language : en
Publisher: Springer Nature
Release Date : 2022-01-31

Breast Cancer written by Suresh Chander Sharma and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-31 with Medical categories.


The book provides detailed information on breast cancer and covers all the aspects of this rapidly spreading disease, such as applied anatomy and physiology, causative factors, various Investigations to reach a concise, definitive and complete diagnosis. The management of breast cancer involves multi-modality treatment and the book describes all the modalities in a very clear manner. It also discusses in a very lucid and practical way. the multi-prong treatment that the patient requires . Additionally, the book covers lesser-known areas of the subject like rehabilitation, management of lymphoedema, Extravasation of chemo-Infusion, organization of breast cancer management group, breast cancer awareness and patient education, follow up of the patient, and psychological support to these patients who have undergone mutilation of their organ. Edited by experts the chapters are contributed by renowned onco-sugeons from high volume and reputed centers in India such as, PGIMER, Chandigarh, AIIMS, New Delhi, and TMH, Mumbai among others. The book serves as a useful resource for surgeons, medical oncologists, radiotherapists, pathologists, radiologists and many other specialists interested in the field of breast cancer and actively working in this area. It is useful for practitioners and residents as well as for those who want to learn the different aspects of this disease.



Precision Medicine And Human Health


Precision Medicine And Human Health
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Author : Farzana Mahdi
language : en
Publisher: Bentham Science Publishers
Release Date : 2024-06-03

Precision Medicine And Human Health written by Farzana Mahdi and has been published by Bentham Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-06-03 with Medical categories.


Precision Medicine and Human Health covers several aspects of precision medicine in 20 edited reviews by researchers and healthcare professionals. The breadth of information provided by the contributors aims to familiarize readers with basic and applied research in personalized therapy. Starting with an overview of the subject and its relationship with epigenetics, the book progresses into advanced topics that explain its wider applications. The use of precision medicine in treating different diseases such as protein misfolding disorders, gut ulcers and their effect on the gut microbiome, cancer treatment (for hepatocellular carcinoma, breast cancer, and oral cancer), fibromyalgia, high altitude sickness, and multiple sclerosis is explained. The book also covers modern therapeutic techniques to administer personalized therapy, including epithelial-mesenchymal therapy (EMT), circadian clock modulation, and artificial intelligence and phytoconstituents. The next chapters cover advanced technologies that are crucial to precision medicine, such as nanomaterials and advanced drug delivery systems. A concluding chapter on the therapeutic use of tannins in precision medicine rounds up the contents. Key Features: - Features 20 focused chapters contributed by scientific experts - Introduces readers to basic concepts in precision medicine - Covers the application of precision medicine in treating different diseases - Showcases several techniques used in experimental and clinical precision therapy - Explains modern technologies in precision medicine - Caters to a wide readership with introductions, structured headings, and references This is an informative reference for healthcare professionals in clinics and hospitals and any scholar who wants to learn about basic and applied knowledge in precision medicine.



Adjuvant Therapy For Breast Cancer


Adjuvant Therapy For Breast Cancer
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Author : Monica Castiglione
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-07-11

Adjuvant Therapy For Breast Cancer written by Monica Castiglione and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-07-11 with Medical categories.


Adjuvant treatment is administered prior to or as follow up to surgical procedures for breast cancer. Proven success in using medical therapies allowing for breast conserving procedures or reducing risk of occurrence. Although there has been much progress towards a cure, including the introduction of new targeted therapies, metastasizing cancer remains highly incurable.



Machine Learning Based Methods For Rna Data Analysis Volume Ii


Machine Learning Based Methods For Rna Data Analysis Volume Ii
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Author : Lihong Peng
language : en
Publisher: Frontiers Media SA
Release Date : 2023-01-02

Machine Learning Based Methods For Rna Data Analysis Volume Ii written by Lihong Peng and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-01-02 with Science categories.