Responses
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Redirection Of Th1 And Th2 Responses
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Author : Robert L. Coffman
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-09
Redirection Of Th1 And Th2 Responses written by Robert L. Coffman and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-09 with Medical categories.
The two major subsets of CD4+ helper T cells, designated Th1 and Th2, have quite different patterns of cytokine production and, as a consequence, have very different roles in immune responses. The articles in this volume review both basic and clinical studies of T cell heterogeneity, including: the mechanisms by which Th1 and Th2 cells develop and maintain their differences in cytokine production; the different roles of Th1 and Th2 cells in allergy, autoimmunity and infectious diseases; the prospects and strategies for therapeutic manipulation of Th1 and Th2 cells; and the control of Th1 and Th2 responses by regulatory T cell subsets. The volume should give the reader a view of the development and function of Th1 and Th2 cells and the attempts to treat immunological diseases with therapies directed towards altering the Th1/Th2 balance.
Differential Radiosensitivity Of First And Second Set Responses To Allogenic And Xenogenic Skin Grafts In Sublethally Irradiated Mice
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Author : M. L. Tyan
language : en
Publisher:
Release Date : 1963
Differential Radiosensitivity Of First And Second Set Responses To Allogenic And Xenogenic Skin Grafts In Sublethally Irradiated Mice written by M. L. Tyan and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1963 with Mice as laboratory animals categories.
Responses Of Plants To Environmental Stresses
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Author : Renata Szymańska
language : en
Publisher: MDPI
Release Date : 2021-09-01
Responses Of Plants To Environmental Stresses written by Renata Szymańska and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-09-01 with Science categories.
Environmental abiotic stresses, such as extreme temperatures, drought, excess light, salinity, and nutrient deficiency, have detrimental effects on plant growth, development, and yield. Plants are equipped with various adaptation mechanisms to cope with such unfavorable conditions. Our understanding of plants’ abiotic stress responses is crucial to maintaining efficient plant productivity. This book on the responses of plants to environmental stresses is an attempt to find answers to several basic questions related to their adaptation and protective mechanisms against abiotic stresses. The following chapters of the book describe examples of plants’ protective strategies, which cover physiological, cellular, biochemical, and genomic mechanisms. This book is aimed for use by advanced students and researchers in the area of stress biology, plant molecular biology and physiology, agriculture, biochemistry, as well as environmental sciences.
Factors Determining Long Term Anti Tumor Responses To Immune Checkpoint Blockade Therapy
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Author : Alison Taylor
language : en
Publisher: Frontiers Media SA
Release Date : 2023-01-31
Factors Determining Long Term Anti Tumor Responses To Immune Checkpoint Blockade Therapy written by Alison Taylor and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-01-31 with Medical categories.
Plant Responses To Environmental Stimuli
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Author : Michel Thellier
language : en
Publisher: Springer
Release Date : 2017-02-24
Plant Responses To Environmental Stimuli written by Michel Thellier and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-02-24 with Science categories.
In this unique book, Michel Thellier has combined recent discoveries with older data dealing with plant memory and its potential role on plant acclimatization to environment stimuli. By placing memory within an evolutionary frame, the author persuades us that a new way of research has opened in plant physiology.Detailing experiments in a simplified manner, that general readers with an interest in this topic will find it easy to follow.
Approaches To Blocking The Immune Response To Gene Transfer With Viral Vectors
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Author : Katherine High
language : en
Publisher: Frontiers E-books
Release Date :
Approaches To Blocking The Immune Response To Gene Transfer With Viral Vectors written by Katherine High and has been published by Frontiers E-books this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.
Viral vectors are superior tools for gene therapy and as a genetic vaccine platform because viruses have evolved to efficiently infect and transfer their genomes to cells. Several impressive successes in viral vector-based gene therapies have been reported in humans, including restoration of vision in patients with Leber’s congenital amaurosis by retinal gene transfer and cures for severe immune deficiencies by gene transfer to hematopoietic stem cells. However, the mammalian immune system has evolved in parallel to fend off invading pathogens such as viruses. Innate and antigen-specific adaptive immune responses against viral vectors and therapeutic transgene products pose serious hurdles for successful gene therapy. Pre-existing immunity in humans, resulting from prior exposure to the parent virus that forms the basis for the gene transfer vehicle may be derived from, often prevents efficient gene transfer. This problem also reduces our ability to use certain vectors for genetic vaccination or in anti-cancer therapy. For these reasons, the gene transfer community has been extensively studying the mechanisms of immune responses against viral vectors and has started to develop strategies and protocols to block or circumvent such responses. Choice, design and engineering of a vector as well as the route of administration/target tissue can be optimized/ altered to minimize immune responses or evade pre-existing immunity. Immune suppression and modulation strategies are being developed in order to minimize inflammation, prevent antibody or T cell responses against vectors, and to promote tolerance to therapeutic gene products. Combinations of these approaches will likely facilitate clinical applications of gene therapy for many target diseases and also aid in vaccine development.
The Psychology Of Survey Response
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Author : Roger Tourangeau
language : en
Publisher: Cambridge University Press
Release Date : 2000-03-13
The Psychology Of Survey Response written by Roger Tourangeau and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-03-13 with Psychology categories.
This valuable book examines the complex psychological processes involved in answering different types of survey questions. Drawing on both classic and modern research from cognitive psychology, social psychology, and survey methodology, the authors examine how survey responses are formulated and they demonstrate how seemingly unimportant features of the survey can affect the answers obtained. The book provides a comprehensive review of the sources of response errors in surveys, and it offers a coherent theory of the relation between the underlying views of the public and the results of public opinion polls. Topics include the comprehension of survey questions, the recall of relevant facts and beliefs, estimation and inferential processes people use to answer survey questions, the sources of the apparent instability of public opinion, the difficulties in getting responses into the required format, and the distortions introduced into surveys by deliberate misreporting.
The Th2 Type Immune Response In Health And Disease
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Author : William C. Gause
language : en
Publisher: Springer
Release Date : 2015-12-08
The Th2 Type Immune Response In Health And Disease written by William C. Gause and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-12-08 with Medical categories.
The type 2 immune response that develops during infectious disease has undergone major paradigm shifts in the last several years as new cell types and pathways have been identified. It is now clear that the type 2 immune response, characterized by elevations in specific cytokines, including IL-4, IL-5 and IL-13, is associated with helminth infections in both humans and mice. This response is complex and includes effector functions that mediate resistance, contributing to expulsion and in some cases destruction, of the parasite. But just as importantly, the type 2 immune response can also mediate tolerance mechanisms, which can mitigate tissue injury as these large multicellular parasites transit through vital organs. The tolerance mechanisms include both tissue repair and immune regulatory effects. These latter aspects of the helminth-induced type 2 immune response are increasingly recognized as a potential resource that can be mined for the development of novel immunotherapies that may enhance wound healing, control of autoimmune and inflammatory diseases and regulation of metabolic homeostasis. In this book, leading researchers in this exciting and dynamic field discuss the latest findings and emerging concepts, providing an intellectual framework that can be used as a basis for new discoveries and potentially new treatments for diseases associated with inflammation.
Response To Intervention
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Author : William N. Bender
language : en
Publisher: Corwin Press
Release Date : 2007-04-05
Response To Intervention written by William N. Bender and has been published by Corwin Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-04-05 with Education categories.
Discover a resource that shows teachers how to implement RTI in the classroom! This practical guide helps educators understand the tiers of the Response to Intervention (RTI) process, as well as how to implement interventions and utilize the results to modify existing instruction for students in the classroom. With vignettes, examples, and reproducible forms based on the problem-solving and standards-based approaches to RTI, this accessible handbook gives teachers the tools to: Document the existence or nonexistence of a learning disability Monitor individual student progress Plan specific follow-up interventions based on a learner's needs Implement strategies to support students' success
Autophagy Infection And The Immune Response
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Author : William T. Jackson
language : en
Publisher: John Wiley & Sons
Release Date : 2014-12-03
Autophagy Infection And The Immune Response written by William T. Jackson and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-12-03 with Science categories.
The relationship between infection and immunity and autophagy, a pathway of cellular homeostasis and stress response, has been a rapidly growing field of study over the last decade. While some cellular processes are pro- or anti-infection, autophagy has been proven to be both: a part of the innate immune response against some microbes, and a cellular pathway subverted by some pathogens to promote their own replication. Autophagy, Infection, and the Immune Response provides a unified overview of the roles of cellular autophagy during microbial infection. Introductory chapters ground the reader by delineating the autophagic pathway from a cellular perspective, and by listing assays available for measuring autophagy. Subsequent chapters address virus interactions with autophagy machinery, the various roles of autophagy parasitic infection, and interactions of bacteria with the autophagic pathway. Concluding chapters explore the relationships of autophagy to systemic immune responses, including antigen presentation, ER stress, and production of IFN-gamma. Designed as a resource for those interested in initiating studies on the relationship between autophagy and infection or immunity, Autophagy, Infection, and the Immune Response combines practical state-of the art technique descriptions with an overview of the wide variety of known interactions between pathogens and the autophagic pathway.