Rna Metabolism In Mitochondria
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Rna Metabolism In Mitochondria
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Author : Jorge Cruz-Reyes
language : en
Publisher: Springer
Release Date : 2018-06-12
Rna Metabolism In Mitochondria written by Jorge Cruz-Reyes and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-06-12 with Science categories.
This volume focuses on mitochondrial RNA metabolism, emphasizing recent discoveries and technological advances in this fast moving area that increase our understanding of mitochondrial gene function. Topics addressed include the interplay of mitochondria with the nucleus and cytosol, structure-function connections, and relevance to human disease. Mitochondria are the powerhouses of the cell, and a great deal is known about mitochondrial energy metabolism. Less well known is the plethora of amazing mechanisms that have evolved to control expression of mitochondrial genomes. Several RNA processes and machineries in protozoa, plants, flies and humans are discussed, including: transcription and RNA polymerase mechanism; tRNA processing of 5′ and 3′ ends; mRNA maturation by nucleotide insertion/deletion editing and by RNA splicing; mRNA stability; and RNA import. Specialized factors and ribonucleoproteins (RNPs) examined include pentatricopeptide repeat (PPR) proteins, RNase P, polymerases, helicases, nucleases, editing and repair enzymes. Remarkable features of these processes and factors are either not found outside mitochondria, differ substantially among eukaryotic lineages, or are unique in biology.
Studies On Rna Metabolism In Hela Mitochondria
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Author : Robert Allen Gelfand
language : en
Publisher:
Release Date : 1980
Studies On Rna Metabolism In Hela Mitochondria written by Robert Allen Gelfand and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1980 with Electronic dissertations categories.
Rna Metabolism In Trypanosomes
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Author : Albrecht Bindereif
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-06-12
Rna Metabolism In Trypanosomes written by Albrecht Bindereif and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-06-12 with Science categories.
Trypanosomes are unicellular protozoa of ancient evolutionary origin that are responsible for several tropical diseases, such as African sleeping sickness. Over the last few decades, research in trypanosome biology has revealed many unique and fascinating features, many of which have helped to establish new paradigms in other biological systems. This applies in particular to studies in gene expression and regulation, which benefit enormously from the trypanosome genome projects and from the new genome-wide approaches recently introduced in trypanosome research. This volume covers the most important aspects of biosynthesis, processing, and functions of RNA in trypanosomes, ranging from transcription to RNA editing, mRNA splicing/translation/turnover, processing of transfer and ribosomal RNA, RNA interference, and current transcriptome-wide analyses. Recent progress in RNA-focused research in trypanosomatids promises to yield novel insights into trypanosome-specific features, as well as to reveal in the process new potential therapeutic strategies for combating these parasitic diseases.
Rna Metabolism In Neurodegenerative Diseases
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Author : Rita Sattler
language : en
Publisher: Springer
Release Date : 2018-06-18
Rna Metabolism In Neurodegenerative Diseases written by Rita Sattler and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-06-18 with Medical categories.
It has become evident over the last years that abnormalities in RNA processing play a fundamental part in the pathogenesis of neurodegenerative diseases. Cellular viability depends on proper regulation of RNA metabolism and subsequent protein synthesis, which requires the interplay of many processes including transcription, pre--‐mRNA splicing, mRNA editing as well as mRNA stability, transport and translation. Dysfunction in any of these processes, often caused by mutations in the coding and non--‐ coding RNAs, can be very destructive to the cellular environment and consequently impair neural viability. The result of this RNA toxicity can lead to a toxic gain of function or a loss of function, depending on the nature of the mutation. For example, in repeat expansion disorders, such as the newly discovered hexanucleotide repeat expansion in theC9orf72 gene found in amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), a toxic gain of function leads to the formation of RNA foci and the sequestration of RNA binding proteins (RBPs). This in return leads to a loss of function of those RBPs, which is hypothesized to play a significant part in the disease progression of ALS and FTD. Other toxicities arising from repeat expansions are the formation of RNA foci, bi--‐directional transcription and production of repeat associated non--‐ATG (RAN) translation products. This book will touch upon most of these disease mechanisms triggered by aberrant RNA metabolism and will therefore provide a broad perspective of the role of RNA processing and its dysfunction in a variety of neurodegenerative disorders, including ALS, FTD, Alzheimer’s disease, Huntington’s disease, spinal muscular atrophy, myotonic dystrophy and ataxias. The proposed authors are leading scientists in the field and are expected to not only discuss their own work, but to be inclusive of historic as well as late breaking discoveries. The compiled chapters will therefore provide a unique collection of novel studies and hypotheses aimed to describe the consequences of altered RNA processing events and its newest molecular players and pathways.
The Rna Metabolism Of Nucleoli And Mitochondria In Mammalian Cells
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Author :
language : en
Publisher:
Release Date : 1969
The Rna Metabolism Of Nucleoli And Mitochondria In Mammalian Cells written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1969 with categories.
Nuclear And Mitochondrial Mutations Affecting Mitochondrial Rna Metabolism
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Author : Heather Miller Conrad
language : en
Publisher:
Release Date : 1987
Nuclear And Mitochondrial Mutations Affecting Mitochondrial Rna Metabolism written by Heather Miller Conrad and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1987 with Mitochondria categories.
Alfabeto De Mam Feros
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Author :
language : en
Publisher:
Release Date : 1881
Alfabeto De Mam Feros written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1881 with categories.
Plant Mitochondria
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Author : Nicolas L. Taylor
language : en
Publisher:
Release Date : 2019
Plant Mitochondria written by Nicolas L. Taylor and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019 with Electronic books categories.
The primary function of mitochondria is respiration, where the catabolism of substrates is coupled to ATP synthesis via oxidative phosphorylation. In plants, mitochondrial composition is relatively complex and flexible and has specific pathways to support photosynthetic processes in illuminated leaves. Plant mitochondria also play important roles in a variety of cellular processes associated with carbon, nitrogen, phosphorus, and sulfur metabolism. Research on plant mitochondria has rapidly developed in the last few decades with the availability of the genome sequences for a wide range of model and crop plants. Recent prominent themes in plant mitochondrial research include linking mitochondrial composition to environmental stress responses, and how this oxidative stress impacts on the plant mitochondrial function. Similarly, interest in the signaling capacity of mitochondria, the role of reactive oxygen species, and retrograde and anterograde signaling has revealed the transcriptional changes of stress responsive genes as a framework to define specific signals emanating to and from the mitochondrion. There has also been considerable interest in the unique RNA metabolic processes in plant mitochondria, including RNA transcription, RNA editing, the splicing of group I and group II introns, and RNA degradation and translation. Despite their identification more than 100 years ago, plant mitochondria remain a significant area of research in the plant sciences. This Special Issue, "Plant Mitochondria", will cover a selection of recent research topics and timely review articles in the field of plant mitochondrial research.
Plant Mitochondria
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Author : Nicolas L. Taylor
language : en
Publisher: MDPI
Release Date : 2019-02-19
Plant Mitochondria written by Nicolas L. Taylor and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-02-19 with Biology (General) categories.
This book is a printed edition of the Special Issue "Plant Mitochondria" that was published in IJMS
Role Of Mitochondria Associated Non Coding Rnas In Intracellular Communication
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Author : Samarjit Das
language : en
Publisher: Frontiers Media SA
Release Date : 2022-09-30
Role Of Mitochondria Associated Non Coding Rnas In Intracellular Communication written by Samarjit Das and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-09-30 with Science categories.
