Rna Spectroscopy

DOWNLOAD
Download Rna Spectroscopy PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get Rna Spectroscopy book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page
Rna
DOWNLOAD
Author : D. Söll
language : en
Publisher: Elsevier
Release Date : 2001-12-03
Rna written by D. Söll and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-12-03 with Science categories.
This publication summarizes the current status of our understanding of RNA, with particular emphasis on the chemistry of this key biological molecule. The various RNAs covered are messenger RNA, ribosomal RNA, transfer RNA and RNA enzymes (ribozymes). The different chapters detail biophysical and chemical methods to investigate RNA structure and function, the synthesis of native and modified RNAs and the latest advances in our understanding of the vast array of biological processes in which RNA is involved.
Rna As A Drug Target
DOWNLOAD
Author : John Schneekloth
language : en
Publisher: John Wiley & Sons
Release Date : 2024-07-01
Rna As A Drug Target written by John Schneekloth and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-07-01 with Medical categories.
Discover a new paradigm in drug discovery that greatly expands the space of addressable drug targets and potential novel drugs Existing paradigms for drug discovery have focused largely on enzymes and other proteins as drug targets. In recent years, however, different varieties of ribonucleic acids have emerged as a viable focus for target-based drug discovery, with the potential to revolutionize the strategy and approach for this essential step in the drug development process. RNA as a Drug Target: The Next Frontier for Medicinal Chemistry offers a practice-oriented introduction to developing drug-like small molecules that selectively modulate both coding and non-coding RNAs. Beginning with a description and characterization of existing druggable RNAs, the book discusses how to approach different RNA targets for drug discovery. The result is a crucial resource for targeting RNAs and creating the next generation of life-saving pharmaceuticals. RNA as a Drug Target readers will also find: A complete “toolbox” for working with RNA, from structure determination to screening and lead generation techniques A wide range of addressable targets and mechanisms, including splicing modulation, riboswitches, targeted degradation, and more Authoritative discussion of the potential of RNA-targeted small molecule therapeutics for drugging the epitranscriptome RNA as a Drug Target provides an expert introduction to a new frontier in pharmaceutical research for medicinal chemists, biochemists, molecular biologists, and members of the pharmaceutical industry.
Rna Structure And Folding
DOWNLOAD
Author : Dagmar Klostermeier
language : en
Publisher: Walter de Gruyter
Release Date : 2013-10-14
Rna Structure And Folding written by Dagmar Klostermeier and has been published by Walter de Gruyter this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-14 with Science categories.
While structure-function relationships of proteins have been studied for a long time, structural studies of RNA face additional challenges. Nevertheless, with the continuous discovery of novel RNA molecules with key cellular functions and of novel pathways and interaction networks, the need for structural information of RNA is still increasing. This volume provides an introduction into techniques to assess structure and folding of RNA. Each chapter explains the theoretical background of one technique, and illustrates possibilities and limitations in selected application examples.
Epr Spectroscopy
DOWNLOAD
Author : Malte Drescher
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-03-06
Epr Spectroscopy written by Malte Drescher and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-03-06 with Science categories.
EPR Spectroscopy in Catalysis, by Sabine Van Doorslaer und Damien M. Murphy Radicals in Flavoproteins, by Erik Schleicher und Stefan Weber EPR Spectroscopy in Polymer Science, by Dariush Hinderberger EPR in Protein Science, by Intrinsically Disordered Proteins, by Malte Drescher Site-Directed Spin Labeling of Membrane Proteins, by Enrica Bordignon Structure and Dynamics of Nucleic Acids, by Ivan Krstić, Burkhard Endeward, Dominik Margraf, Andriy Marko und Thomas F Prisner New Directions in Electron Paramagnetic Resonance Spectroscopy on Molecular Nanomagnets, by J. van Slageren
Handbook Of Rna Biochemistry
DOWNLOAD
Author : Roland K. Hartmann
language : en
Publisher: John Wiley & Sons
Release Date : 2015-06-22
Handbook Of Rna Biochemistry written by Roland K. Hartmann and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-06-22 with Science categories.
The second edition of a highly acclaimed handbook and ready reference. Unmatched in its breadth and quality, around 100 specialists from all over the world share their up-to-date expertise and experiences, including hundreds of protocols, complete with explanations, and hitherto unpublished troubleshooting hints. They cover all modern techniques for the handling, analysis and modification of RNAs and their complexes with proteins. Throughout, they bear the practising bench scientist in mind, providing quick and reliable access to a plethora of solutions for practical questions of RNA research, ranging from simple to highly complex. This broad scope allows the treatment of specialized methods side by side with basic biochemical techniques, making the book a real treasure trove for every researcher experimenting with RNA.
Biological And Biomedical Infrared Spectroscopy
DOWNLOAD
Author : A. Barth
language : en
Publisher: IOS Press
Release Date : 2009-09-02
Biological And Biomedical Infrared Spectroscopy written by A. Barth and has been published by IOS Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-09-02 with Medical categories.
Although infrared spectroscopy has been applied with success to the study of important biological and biomedical processes for many years, key advances in this vibrant technique have led to its increasing use, ranging from characterisation of individual macromolecules (DNA, RNA, lipids, proteins) to human tissues, cells and their components. Infrared spectroscopy thus has a significant role to play in the analysis of the vast number of genes and proteins being identified by the various genomic sequencing projects. Whilst this book gives an overview of the field it highlights more recent developments, such as the use of bright synchrotron radiation for recording infrared spectra, the development of two-dimensional infrared spectroscopy and the ability to record infrared spectra at ultrafast speeds. The main focus is on the mid-infrared region, since the great majority of studies are carried out in this region but there is increasing use of the near infrared for biomedical applications and a chapter is devoted to this part of the spectrum. Major advances in theoretical analysis have also enabled better interpretation of the infrared spectra of biological molecules and these are covered. The editors, Professor Andreas Barth of Stockholm University, Stockholm, Sweden and Dr Parvez I. Haris of De Montfort University, Leicester, U.K., who both have extensive research experience in biological infrared spectroscopy per se and in its use in the solution of biophysical problems, have felt it timely therefore to bring together this book. The book is intended for use both by research scientists already active in the use of biological infrared spectroscopy and for those coming new to the technique. Graduate students will also find it useful as an introduction to the technique.
Coherent Multidimensional Spectroscopy
DOWNLOAD
Author : Minhaeng Cho
language : en
Publisher: Springer
Release Date : 2019-08-06
Coherent Multidimensional Spectroscopy written by Minhaeng Cho and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-08-06 with Science categories.
This book will fulfill the needs of time-domain spectroscopists who wish to deepen their understanding of both the theoretical and experimental features of this cutting-edge spectroscopy technique. Coherent Multidimensional Spectroscopy (CMDS) is a state-of-the-art technique with applications in a variety of subjects like chemistry, molecular physics, biochemistry, biophysics, and material science. Due to dramatic advancements of ultrafast laser technologies, diverse multidimensional spectroscopic methods utilizing combinations of THz, IR, visible, UV, and X-ray radiation sources have been developed and used to study real time dynamics of small molecules in solutions, proteins and nucleic acids in condensed phases and membranes, single and multiple excitons in functional materials like semiconductors, quantum dots, and solar cells, photo-excited states in light-harvesting complexes, ions in battery electrolytes, electronic and conformational changes in charge or proton transfer systems, and excess electrons and protons in water and biological systems.
Structure And Biophysics New Technologies For Current Challenges In Biology And Beyond
DOWNLOAD
Author : Joseph D. Puglisi
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-04-26
Structure And Biophysics New Technologies For Current Challenges In Biology And Beyond written by Joseph D. Puglisi and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-04-26 with Science categories.
This volume is a collection of articles from the proceedings of the ISSBMR 7th Course: Structure and Biophysics - New Technologies for Current Challenges in Biology and Beyond. This NATO Advanced Institute (ASI) was held in Erice at the Ettore Majorana Foundation and Centre for Scientific Culture in June 2005. It presents state of the art information on NMR spectroscopy and its place in the broader field of biophysics.
Biomolecular Nmr Spectroscopy
DOWNLOAD
Author : A.J. Dingley
language : en
Publisher: Sage Publications Limited
Release Date : 2011-01-18
Biomolecular Nmr Spectroscopy written by A.J. Dingley and has been published by Sage Publications Limited this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-01-18 with Medical categories.
Nuclear Magnetic Resonance (NMR) spectroscopy is the most powerful technique for characterisation of biomolecular structures at atomic resolution in the solution state. This timely book, entitled Biomolecular NMR Spectroscopy, focuses on the latest state-of-the-art NMR techniques for characterisation of biological macromolecules in the solid and solution state. The editors, Dr Andrew Dingley (University of Auckland, New Zealand) and Dr Steven Pascal (Massey University, New Zealand) have organised the book into four sections, covering the following topics: (i) sample preparation, (ii) structure and dynamics of proteins, (iii) structure and dynamics of nucleic acids and protein-nucleic acid complexes and (iv) rapid and hybrid techniques, including the latest advances in NMR data acquisition and structural analysis, and approaches that combine NMR data with data from complementary physical techniques. The book will be a valuable resource for experienced scientists in academia, government and public services and in industry. It will also be suitable for newcomers and graduate students entering the field of biomolecular NMR spectroscopy.
Rna Recognition
DOWNLOAD
Author :
language : en
Publisher: Academic Press
Release Date : 2019-06-23
Rna Recognition written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-06-23 with Science categories.
RNA Recognition, Volume 623, the latest volume in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. This updated volume covers a variety of topics, including The Preparation of cooperative RNA recognition complexes for crystallographic structural studies, Methods for thermal denaturation studies of fluorogenic aptamers, Dynamic combinatorial chemistry as a rapid, fragment-based approach to RNA-targeted compound discovery, Using a click chemistry assay to identify natural product ligands for pre-microRNAs, Lessons from exploration of chemical and structural small molecule:RNA space, Using ligand-observed NMR to study RNA-small molecule interactions, and much more. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in the Methods in Enzymology series - Includes the latest information on RNA Recognition