Signal Transduction Via Intracellular Calcium Stores
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Signal Transduction Via Intracellular Calcium Stores
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Author : James D. Johnson
language : en
Publisher:
Release Date : 2013-12-01
Signal Transduction Via Intracellular Calcium Stores written by James D. Johnson and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-12-01 with Science categories.
Calcium Signaling
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Author : Roman Brown
language : en
Publisher:
Release Date : 2022-09-13
Calcium Signaling written by Roman Brown and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-09-13 with categories.
Calcium signaling is a step in signal transduction that makes use of calcium ions to communicate and drive intracellular processes. Calcium ions play an important role in cellular signaling because when they enter the cytosol of the cell, they exert allosteric effects on many enzymes and proteins. The resting concentration of calcium ions in the cytoplasm is 100 nM and this is much lower than the extracellular concentration. Calcium ions are continuously pumped from cytosol to extracellular space to maintain this low concentration. Cell signaling occurs when the cell releases calcium ions from intracellular stores, and when calcium ions enter the cell via the ion channels present in the plasma membrane. The aim of this book is to present recent researches in the field of calcium signaling. It includes some of the vital pieces of work being conducted across the world, on various topics related to calcium signaling. This book will help new researchers by foregrounding their knowledge in this branch.
Alterations In Calcium Mediated Signal Transduction And Intracellular Calcium Stores After Traumatic Injury Of Cortical Neurons
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Author : John Thomas Weber
language : en
Publisher:
Release Date : 1999
Alterations In Calcium Mediated Signal Transduction And Intracellular Calcium Stores After Traumatic Injury Of Cortical Neurons written by John Thomas Weber and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with categories.
Calcium Entry Channels In Non Excitable Cells
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Author : Juliusz Ashot Kozak
language : en
Publisher: CRC Press
Release Date : 2017-07-14
Calcium Entry Channels In Non Excitable Cells written by Juliusz Ashot Kozak and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-07-14 with Science categories.
Calcium Entry Channels in Non-Excitable Cells focuses on methods of investigating the structure and function of non-voltage gated calcium channels. Each chapter presents important discoveries in calcium entry pathways, specifically dealing with the molecular identification of store-operated calcium channels which were reviewed by earlier volumes in the Methods in Signal Transduction series. Crystallographic and pharmacological approaches to the study of calcium channels of epithelial cells are also discussed. Calcium ion is a messenger in most cell types. Whereas voltage gated calcium channels have been studied extensively, the non-voltage gated calcium entry channel genes have only been identified relatively recently. The book will fill this important niche.
Vascular Ion Channels In Physiology And Disease
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Author : Irena Levitan, PhD
language : en
Publisher: Springer
Release Date : 2016-07-06
Vascular Ion Channels In Physiology And Disease written by Irena Levitan, PhD and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-07-06 with Medical categories.
Ion channels are the major class of membrane proteins responsible for rapid and regulated transport of ions across biological membranes and for the generation and propagation of electrical signals in the brain, heart, and skeletal and vascular tissues. Ion channels are also known to play critical roles in regulation of cell proliferation, insulin secretion and intracellular signaling in a variety of cell types. This book focuses on the roles of ion channels in vascular tissues under normal and pathological conditions. Vascular abnormalities are known to underlie a plethora of severe pathological conditions, such as atherosclerosis, systemic and pulmonary hypertension, coronary or cerebral vasospasm, and diabetes. In addition, misregulated angiogenesis is one of the major contributors to the development of tumors. Therefore, it is clearly imperative to obtain a better understanding of the molecular mechanisms that contribute to vascular disorders. This book will be the first comprehensive assembly of assays to present the studies that have been done during the last decade to elucidate the roles of ion channels in different vascular diseases.
Signaling Mechanisms Regulating T Cell Diversity And Function
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Author : Jonathan Soboloff
language : en
Publisher: CRC Press
Release Date : 2017-03-27
Signaling Mechanisms Regulating T Cell Diversity And Function written by Jonathan Soboloff and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-03-27 with Medical categories.
T cells play a vital role mediating adaptive immunity, a specific acquired resistance to an infectious agent produced by the introduction of an antigen. There are a variety of T cell types with different functions. They are called T cells, because they are derived from the thymus gland. This volume discusses how T cells are regulated through the operation of signaling mechanisms. Topics covered include positive and negative selection, early events in T cell receptor engagement, and various T cell subsets.
Protein Kinase Mediated Decisions Between Life And Death
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Author : Ayse Basak Engin
language : en
Publisher: Springer Nature
Release Date : 2021-02-04
Protein Kinase Mediated Decisions Between Life And Death written by Ayse Basak Engin and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-02-04 with Medical categories.
Protein phosphorylation via protein kinases is an inevitable process that alters physiological and pathological functions of the cells. Thus, protein kinases play key roles in the regulation of cell life or death decisions. Protein kinases are frequently a driving factor in a variety of human diseases including aging and cellular senescence, immune system and endothelial dysfunctions, cancers, insulin resistance, cholestasis and neurodegenerative diseases, as well as bacterial resistance in persistent infections. Recent developments in quantitative proteomics provide important opinions on kinase inhibitor selectivity and their modes of action in the biological context. Protein Kinase-mediated Decisions Between Life and Death aims to have the reader catch insights about up-to-date opinions on “Protein Kinases” related pathways that threaten human health and life. As “Protein Kinases” are related to many health problems, clinicians, basic science researchers and students need this information. Chapter “Signal Transduction in Immune Cells and Protein Kinases” is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Trp Ion Channel Function In Sensory Transduction And Cellular Signaling Cascades
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Author : Wolfgang B. Liedtke, MD, PH.D.
language : en
Publisher: CRC Press
Release Date : 2006-09-29
Trp Ion Channel Function In Sensory Transduction And Cellular Signaling Cascades written by Wolfgang B. Liedtke, MD, PH.D. and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-09-29 with Medical categories.
Since the first TRP ion channel was discovered in Drosophila melanogaster in 1989, the progress made in this area of signaling research has yielded findings that offer the potential to dramatically impact human health and wellness. Involved in gateway activity for all five of our senses, TRP channels have been shown to respond to a wide range of st
Microglia In The Regenerating And Degenerating Central Nervous System
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Author : Wolfgang J. Streit
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-14
Microglia In The Regenerating And Degenerating Central Nervous System written by Wolfgang J. Streit and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-14 with Science categories.
The study of microglial cells has recently gained importance for those researching degeneration and regeneration. Microglia in the regenerating and degenerating CNS supports the assertion that understanding microglial biology could perhaps be pivotal for unraveling the pathogenetic mechanisms that underlie Alzheimer's disease, In addition, microglia are also critical for understanding the sequelae of traumatic brain and spinal cord injury, and for the important post-traumatic repair processes. This book gives an up to date account of the role of microglia in degeneration and regeneration of the nervous system and reviews their cell function and physiology.
Store Operated Calcium Channels
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Author :
language : en
Publisher: Academic Press
Release Date : 2013-07-24
Store Operated Calcium Channels written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-07-24 with Science categories.
Store-operated calcium channels are found in most animal cells and regulate many cellular functions including cell division, growth, differentiation, and cell death. This volume provides a concise and informative overview of the principles of store-operated calcium entry and the key developments in the field from researchers who have led these advances. The overall goal of the volume is to provide interested students and investigators with sufficient information to enable a broad understanding of the progress and current excitement in the field. The volume contains a wealth of information that even experienced investigators in the field will find useful. The volume provides a comprehensive overview of the mechanisms and functions of store-operated calcium channels Contributors are authoritative researchers who have produced important advances in the field The volume is well-illustrated with cartoons and data to facilitate easy comprehension of the subject