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Sleep And Alertness Management In Military Operations Pharmacology Methods And Animal Models


Sleep And Alertness Management In Military Operations Pharmacology Methods And Animal Models
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Sleep And Alertness Management In Military Operations Pharmacology Methods And Animal Models


Sleep And Alertness Management In Military Operations Pharmacology Methods And Animal Models
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Author : R. W. Bustker
language : en
Publisher:
Release Date : 2000

Sleep And Alertness Management In Military Operations Pharmacology Methods And Animal Models written by R. W. Bustker and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000 with categories.




Sleep And Alertness Management I Pharmacokinetics Of Hypnotics And Alertness Enhancers In Marmoset Monkeys Slaap En Alertheidsmanagement I Farmacokinetiek Van Slaap En Alertheidsverhogendemiddelen In Marmosetapen


Sleep And Alertness Management I Pharmacokinetics Of Hypnotics And Alertness Enhancers In Marmoset Monkeys Slaap En Alertheidsmanagement I Farmacokinetiek Van Slaap En Alertheidsverhogendemiddelen In Marmosetapen
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Author :
language : en
Publisher:
Release Date : 2006

Sleep And Alertness Management I Pharmacokinetics Of Hypnotics And Alertness Enhancers In Marmoset Monkeys Slaap En Alertheidsmanagement I Farmacokinetiek Van Slaap En Alertheidsverhogendemiddelen In Marmosetapen written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with categories.


In earlier studies, possible solutions with direct usefulness in crew endurance plans were recommended; among the recommendations was the use of sleep-inducing and wake-promoting drugs. However, any pharmacological intervention may result in unwanted side-effects. Therefore, for sleep and alertness management in a military setting a combination of a short acting hypnotic drug and a fast acting stimulant drug are preferred. Human pharmacokinetics are usually well-known for approved drugs. However, if these drugs are to be used in a novel animal model setting (the marmoset), pharmacokinetics will be different and need to be re-assessed. Therefore, in this study, the pharmacokinetics of the short acting hypnotic drugs temazepam,%%zolpidem and zaleplon, and the alertness enhancers flumazenil, caffeine and modafinil were investigated to determine whether they fulfill the prerequisites of short and fast action to allow the use of these drugs in aiding sleep and enhancing alertness during military service. In order to attain this goal, sensitive and selective methods of sample preparation and analysis (HPLC and (IC-MS) were developed by using high quality separation and detection methods. The blood samples were obtained using a low-stress protocol which makes the use of an anesthetic unnecessary. This also prevents possible intervention with the anesthetic drug with the drugs under investigation.



Assessment Of Long Term Health Effects Of Antimalarial Drugs When Used For Prophylaxis


Assessment Of Long Term Health Effects Of Antimalarial Drugs When Used For Prophylaxis
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Author : National Academies of Sciences, Engineering, and Medicine
language : en
Publisher: National Academies Press
Release Date : 2020-04-24

Assessment Of Long Term Health Effects Of Antimalarial Drugs When Used For Prophylaxis written by National Academies of Sciences, Engineering, and Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-04-24 with Medical categories.


Among the many who serve in the United States Armed Forces and who are deployed to distant locations around the world, myriad health threats are encountered. In addition to those associated with the disruption of their home life and potential for combat, they may face distinctive disease threats that are specific to the locations to which they are deployed. U.S. forces have been deployed many times over the years to areas in which malaria is endemic, including in parts of Afghanistan and Iraq. Department of Defense (DoD) policy requires that antimalarial drugs be issued and regimens adhered to for deployments to malaria-endemic areas. Policies directing which should be used as first and as second-line agents have evolved over time based on new data regarding adverse events or precautions for specific underlying health conditions, areas of deployment, and other operational factors At the request of the Veterans Administration, Assessment of Long-Term Health Effects of Antimalarial Drugs When Used for Prophylaxis assesses the scientific evidence regarding the potential for long-term health effects resulting from the use of antimalarial drugs that were approved by FDA or used by U.S. service members for malaria prophylaxis, with a focus on mefloquine, tafenoquine, and other antimalarial drugs that have been used by DoD in the past 25 years. This report offers conclusions based on available evidence regarding associations of persistent or latent adverse events.



Food Components To Enhance Performance


Food Components To Enhance Performance
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Author : Institute of Medicine
language : en
Publisher: National Academies Press
Release Date : 1994-02-01

Food Components To Enhance Performance written by Institute of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994-02-01 with Medical categories.


The physiological or psychological stresses that employees bring to their workplace affect not only their own performance but that of their co-workers and others. These stresses are often compounded by those of the job itself. Medical personnel, firefighters, police, and military personnel in combat settingsâ€"among othersâ€"experience highly unpredictable timing and types of stressors. This book reviews and comments on the performance-enhancing potential of specific food components. It reflects the views of military and non-military scientists from such fields as neuroscience, nutrition, physiology, various medical specialties, and performance psychology on the most up-to-date research available on physical and mental performance enhancement in stressful conditions. Although placed within the context of military tasks, the volume will have wide-reaching implications for individuals in any job setting.



Use Of Dietary Supplements By Military Personnel


Use Of Dietary Supplements By Military Personnel
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Author : Institute of Medicine
language : en
Publisher: National Academies Press
Release Date : 2008-10-31

Use Of Dietary Supplements By Military Personnel written by Institute of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-10-31 with Technology & Engineering categories.


Dietary supplements are widely available through a rapidly expanding market of products commonly advertised as beneficial for health, performance enhancement, and disease prevention. Given the importance and frequent evaluation of physical performance and health as a criteria to join and remain in the military, the use of these products by military personnel has raised concern regarding over-all and long-term efficacy and safety. This evaluation is especially difficult, as many of these supplements contain multiple ingredients, have a changing composition over time, or are used intermittently at doses difficult to measure. This book analyzes the patterns of dietary supplement use among military personnel, examines published reviews of the scientific evidence, and identifies those dietary supplements that are beneficial and/or warrant concern due to risks to health or performance. The book also recommends a system to monitor adverse health effects and a framework to identify the need for active management of dietary supplements by military personnel. Military policy makers, personnel, and recruits will find this book useful, as will nutritionists, athletes, and others working in strenuous environments.



Chronobiology And Obesity


Chronobiology And Obesity
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Author : Marta Garaulet
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-11-13

Chronobiology And Obesity written by Marta Garaulet and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-11-13 with Medical categories.


Circadian rhythms are such an innate part of our lives that we rarely pause to speculate why they even exist. Some studies have suggested that the disruption of the circadian system may be causal for obesity and manifestations of Metabolic Syndrome (MetS). Shift-work, sleep-deprivation and bright-light-exposure at night are related to increased adiposity (obesity) and prevalence of MetS. It has been provided evidence of clock genes expression in human adipose tissue and demonstrated its association with different components of the MetS. Moreover, current studies are illustrating the particular role of different clock genes variants and their predicted haplotypes in MetS. The purpose of “Chronobiology and Obesity” is to describe the mechanisms implicated in the interaction between chonodisruption and metabolic-related illnesses, such as obesity and MetS, with different approaches.



Government Reports Announcements Index


Government Reports Announcements Index
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Author :
language : en
Publisher:
Release Date : 1987

Government Reports Announcements Index written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1987 with Science categories.




The 71f Advantage


The 71f Advantage
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Author : National Defense University Press
language : en
Publisher: NDU Press
Release Date : 2010-09

The 71f Advantage written by National Defense University Press and has been published by NDU Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-09 with Psychology categories.


Includes a foreword by Major General David A. Rubenstein. From the editor: "71F, or "71 Foxtrot," is the AOC (area of concentration) code assigned by the U.S. Army to the specialty of Research Psychology. Qualifying as an Army research psychologist requires, first of all, a Ph.D. from a research (not clinical) intensive graduate psychology program. Due to their advanced education, research psychologists receive a direct commission as Army officers in the Medical Service Corps at the rank of captain. In terms of numbers, the 71F AOC is a small one, with only 25 to 30 officers serving in any given year. However, the 71F impact is much bigger than this small cadre suggests. Army research psychologists apply their extensive training and expertise in the science of psychology and social behavior toward understanding, preserving, and enhancing the health, well being, morale, and performance of Soldiers and military families. As is clear throughout the pages of this book, they do this in many ways and in many areas, but always with a scientific approach. This is the 71F advantage: applying the science of psychology to understand the human dimension, and developing programs, policies, and products to benefit the person in military operations. This book grew out of the April 2008 biennial conference of U.S. Army Research Psychologists, held in Bethesda, Maryland. This meeting was to be my last as Consultant to the Surgeon General for Research Psychology, and I thought it would be a good idea to publish proceedings, which had not been done before. As Consultant, I'd often wished for such a document to help explain to people what it is that Army Research Psychologists "do for a living." In addition to our core group of 71Fs, at the Bethesda 2008 meeting we had several brand-new members, and a number of distinguished retirees, the "grey-beards" of the 71F clan. Together with longtime 71F colleagues Ross Pastel and Mark Vaitkus, I also saw an unusual opportunity to capture some of the history of the Army Research Psychology specialty while providing a representative sample of current 71F research and activities. It seemed to us especially important to do this at a time when the operational demands on the Army and the total force were reaching unprecedented levels, with no sign of easing, and with the Army in turn relying more heavily on research psychology to inform its programs for protecting the health, well being, and performance of Soldiers and their families."



Integrative Preventive Medicine


Integrative Preventive Medicine
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Author : Richard H. Carmona
language : en
Publisher: Oxford University Press
Release Date : 2017-12-12

Integrative Preventive Medicine written by Richard H. Carmona and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-12-12 with Medical categories.


For most clinicians, the science and evidence for many integrative therapies is largely unknown or considered suspect. Most physicians don't have time to learn integrative approaches and aren't sure what to recommend or which approaches have merit or improved outcomes. Here, clinicians have easy access to the best practices in integrative medicine and expectations for outcomes



Military Strategy A Very Short Introduction


Military Strategy A Very Short Introduction
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Author : Antulio J. Echevarria II
language : en
Publisher: Oxford University Press
Release Date : 2024

Military Strategy A Very Short Introduction written by Antulio J. Echevarria II and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024 with History categories.


Military Strategy: A Very Short Introduction adapts Clausewitz's framework to highlight the dynamic relationship between the main elements of strategy: purpose, method, and means. Drawing on historical examples, Antulio J. Echevarria discusses the major types of military strategy and how emerging technologies are affecting them. This second edition has been updated to include an expanded chapter on manipulation through cyberwarfare and new further reading.