Steroid Protein Interactions
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Steroid Protein Interactions
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Author : Ulrich Westphal
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Steroid Protein Interactions written by Ulrich Westphal and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
This is the story of steroid-protein interactions as one investigator sees it. Following the general concept of this monograph series, it emphasizes the results and interpretations obtained in the author's laboratory, and is therefore a subjective account. Recognizing, how ever, that the discussion of the subject would be incomplete if the material were limited to one scientist's work, the essential achieve ments of other investigators have been incorporated. An effort has thus been made to give a balanced presentation and to enable the reader to see in perspective the varied facets of the interactions between steroids and proteins. Since this is the first comprehensive treatment of the topic, it seems appropriate to go to the roots, and try to find out how it all started. The first chapters, therefore, take the reader to the laboratories of those who very early conceived the significance of the attachment of dyes, drugs, and other conspicuous molecules to those colloids called proteins. The discovery of the steroid hormones set the stage for meaningful investigation of their interaction with proteins of various origins and functions - a process which is continuing today with increasing vigor.
Steroid Protein Interactions Ii
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Author : Ulrich Westphal
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Steroid Protein Interactions Ii written by Ulrich Westphal and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Steroid Protein Interactions
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Author : H. Leon Bradlow
language : en
Publisher:
Release Date : 1988
Steroid Protein Interactions written by H. Leon Bradlow and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988 with categories.
Steroid Protein Interactions Basic And Clinical Aspects Second International Symposium On Binding Proteins
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Author : Roberto Frairia
language : en
Publisher:
Release Date : 1988
Steroid Protein Interactions Basic And Clinical Aspects Second International Symposium On Binding Proteins written by Roberto Frairia and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988 with Protein binding categories.
Steroid Protein Interactions
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Author : J. Victor Baldridge
language : en
Publisher:
Release Date : 1971
Steroid Protein Interactions written by J. Victor Baldridge and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1971 with categories.
Steroid Protein Interactions
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Author :
language : en
Publisher:
Release Date : 1987
Steroid Protein Interactions written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1987 with categories.
Steroid Protein Interactions
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Author : E. T. Davidson
language : en
Publisher:
Release Date : 1962
Steroid Protein Interactions written by E. T. Davidson and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1962 with categories.
Steroid Protein Interactions
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Author : Roberto Frairia
language : en
Publisher:
Release Date : 1988
Steroid Protein Interactions written by Roberto Frairia and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988 with Protein binding categories.
Steroid Protein Interactions
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Author : Ulrich Westphal
language : en
Publisher:
Release Date : 1965
Steroid Protein Interactions written by Ulrich Westphal and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1965 with Adrenocortical hormones categories.
Studies on the binding of progesterone to alpha-1-acid glycoprotein were continued. A decreasing effect of traces of heavy metals, especially Fe(++), on the binding affinity was observed. Complete deionization of the test system is necessary. Purification of human corticosteroid-binding blobulin (CBG) by DEAE cellulose chromatography and hydroxylapatite adsorption procedures resulted in an overall concentration of about 700-fold. Application of similar chromatographic techniques, including sephadex G-200 fractionation, to rabbit serum yielded preparations that were purified approximately 2000-fold. Sera of man, monkey, rat, rabbit and guinea pig were freed of endogenous corticosteroids by sephadex filtration at 45C. The binding affinities of these sera were then determined by multiple equilibrium dialysis at five concentrations each of cortisol, corticosterone and progesterone, at 4C and 37C. Concentrations of corticosteroid-binding sites and their association constants were determined. (Author).
Research On Steroids
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Author : M. Finkelstein
language : en
Publisher: Elsevier
Release Date : 2013-10-22
Research On Steroids written by M. Finkelstein and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-22 with Nature categories.
Research on Steroids contains the proceedings of the Fourth Meeting of the International Study Group for Steroid Hormones. The papers explore the production, chemical characterization, and metabolism of steroid hormones and their interactions with proteins. Topics range from the action of estradiol in vitro to water-soluble metabolites of estrogens, transport of steroids by proteins, and immunological aspects of steroid hormones. The binding of steroids by tissue proteins is also discussed, along with the use of specific plasma proteins for the determination of steroids. This volume is comprised of 38 chapters and begins with an overview of the general aspects of steroid-protein interaction, followed by a discussion on quantitative studies of steroid binding proteins; aromatization of testosterone by human placenta enzymes; relationship between plasma binding and 5a-reduction of testosterone; cortisol-binding capacity of plasma transcortin in subjects treated with various anabolic steroids; and plasma testosterone binding capacity and estrogen excretion in normal and pathological pregnancies. Subsequent chapters deal with the interaction between estrogenic and carcinogenic substances in the rat mammary gland; influence of steroid production on serum albumin in Cushing's syndrome; and nuclear estradiol binding proteins in the uterus. This book will be of interest to biochemists, biologists, and physiologists.