Steroid Receptors And Disease
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Steroid Receptors In Health And Disease
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Author : Virinder Moudgil
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-09
Steroid Receptors In Health And Disease written by Virinder Moudgil and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-09 with Medical categories.
During the last two decades, progress in steroid hormone research has resulted in the development of new approaches to contraception as well as diagnosis and treatment of endocrine disorders and cancers. Although significant advances have been made in the purification, characterization, immunochemistry and molecular biology of steroid receptors, the precise molecular mechanism of steroid hormone action has remained obscure. This book captures the detailed presentations made at the first conference on Steroid Receptors in Health and Disease held at Meadow Brook Hall, Oakland University in the fall of 1987. The purpose of this international con ference was to facilitate scientific exchange toward a better understand ing of the mode of action of steroid hormones. The scientific sessions consisted of poster presentations and state-of-the-art lectures, the latter of which make up this volume. The first chapter is meant to provide the reader with a more general background of the topics covered in the book, as well as to discuss certain theme-related issues that are either not yet well-established or accepted or are in the stage of infancy. It is hoped that this volume will serve as a useful treatise for students and investigators interested in basic and clinical aspects of biological regulation by steroid hormones. A task of this magnitude could not have been undertaken without the encouragement, advice and continued generous assistance of the members of the scientific committee. I am gratefully indebted to Drs.
Steroid Receptors And Disease
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Author : Peter J. Sheridan
language : en
Publisher:
Release Date : 1988
Steroid Receptors And Disease written by Peter J. Sheridan and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988 with Medical categories.
Steroid Hormone Receptors Basic And Clinical Aspects
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Author : V. K. Moudgil
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-13
Steroid Hormone Receptors Basic And Clinical Aspects written by V. K. Moudgil and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-13 with Medical categories.
The past few years have witnessed the emergence of steroid hormones as the wonder molecules which generate as much discussion in the scientific literature as they do in a typical living room. This transition has been a result of the tremendous public and scientific interest in the normal functioning of the hor mones as well their suggested involvement in several clinical conditions. In the recent past, notable scientific and technological advances have been made in the areas of contraception and regulation of fertility. Steroid receptors are the indis pensable mediators of hormonal responses and are complex protein molecules which appear to exist in association with other, yet undefined, proteins and/or factors. Receptors for vitamin D, retinoic acid and the thyroid hormones share structural similarities with steroid receptors, and the roster of this superfamily is still expanding. While our knowledge of the diversity and magnitude of steroid effects has advanced, the precise mode of steroid hormone action has alluded investigators. This volume brings together an international team of prominent investigators who discuss their most recent work on the basic and clinical aspects of steroid/nuclear receptors. The contributions represent updated versions of the invited presentations made at The Second Meadow Brook Conference on Steroid Receptors in Health and Disease. I am grateful to my colleagues on the Scientific Committee: Etienne Baulieu, Jack Gorski, Benita Katzenellenbogen, David Toft and James WittJiff, who provided the vision and guidance in formulating an out standing program.
Steroid Receptors And Disease
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Author : Peter J. Sheridan
language : en
Publisher:
Release Date :
Steroid Receptors And Disease written by Peter J. Sheridan and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.
The Identities Of Membrane Steroid Receptors
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Author : Cheryl S. Watson
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
The Identities Of Membrane Steroid Receptors written by Cheryl S. Watson and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
Cheryl S. Watson University o/Texas Medical Branch Cellular steroid action has been thoroughly studied in the nuclear compartment. However, nuclear steroid receptor mechanisms have been unable to explain some of the rapid activities of steroids, partiCUlarly those which occur in a time frame of seconds to minutes [reviewed in (1;2)]. Based on these and other considerations, an alternative membrane-associated receptor form was long ago proposed to exist (3). Others interpret the location of the steroid receptors mediating these rapid effects as peri membrane or cytoplasmic. New experimental tools have been brought to bear on the topic of receptors for steroids which mediate non-genomic actions, and thus investigative activity and focus regarding this type of steroid receptor has recently increased significantly. However, there may be multiple answers to the question "how do steroids mediate rapid nongenomic effects?" Steroid actions initiated at the cell membrane can impinge on important phases in the lifespan of a cell: proliferation, migration, differentiation, and release of hormones or neurotransmitters functioning as signals to other cells.
Immunocytochemistry For Steroid Receptors
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Author : Louis P. Pertschuk
language : en
Publisher: CRC Press
Release Date : 1990-08-15
Immunocytochemistry For Steroid Receptors written by Louis P. Pertschuk and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1990-08-15 with Medical categories.
A comprehensive review of the literature on steroid hormone receptor immuncytochemistry. It includes the development of the first monoclonal antireceptor antibody and initial procedures designed to localize steroid receptors in situ up to the present. The step-by-step instructions provide easy reading of topics such as tissue handling, processing, and interpretation. This text places particular emphasis on the studies of human material-especially mammary carcinoma. It presents specific details with chapters on estrogen and progesterone receptors in breast malignancies and benign breast disease. Each section of this outstanding book contains comprehensive photomicrographs that illustrate the most salient features discussed. Detailed graphs pertaining to theoretical particulars concerning technology and the relationship between image analysis and endocrine response are also included. This monograph is an excellent resource for all researchers concerned with hormone-dependent tissues, pathologists who have an interest in working with novel techniques for localizing steroid hormone receptors, and oncologists who must use assay results in the treatment of breast cancer.
Steroid Hormone Receptors In Health And Disease
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Author : Raj Kumar
language : en
Publisher: Elsevier
Release Date : 2023-12-15
Steroid Hormone Receptors In Health And Disease written by Raj Kumar and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-12-15 with Medical categories.
Steroid Hormone Receptors in Endocrine Physiology and Diseases covers the role of steroid hormones in human physiology and receptor activity in the pathophysiology of disease. The book discusses how these receptors can be used as therapeutic targets for the treatment of conditions from cancer to aging, offering immediate applications of biochemical principles into clinical applications such as diagnosis and treatment. This book is a valuable reference for graduate and postdoctoral scientists but is also ideal for medical students interested in the functional role of various steroid hormone receptors in a wide variety of endocrine related diseases.Steroid hormone receptors (SHRs) are known to play vital roles in normal physiology through the control of development, differentiation, metabolic homeostasis and reproduction. Due to their involvement in various pathological and disease conditions, SHRs are also important therapeutic targets in several disorders including inflammation, autoimmune diseases, hormone-dependent cancers, osteoporosis and cardiovascular diseases. Discusses the importance of steroid hormone receptors in the physiology and pathophysiology of various endocrine related diseases Provides state-of-the-art information based on key research findings in the field, along with hypotheses and perspectives for future directions for basic and translational research and clinical applications Offers a comprehensive description of the challenges associated with steroid hormone receptors-based therapies
Localization Of Putative Steroid Receptors
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Author : Pertschuk
language : en
Publisher: CRC Press
Release Date : 2018-02-01
Localization Of Putative Steroid Receptors written by Pertschuk and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-02-01 with Medical categories.
These volumes represent the "state-of-the-art" in morphological methods for detection of steroid receptors. Some physician authors have applied many of the new methodologies in clinical research projects deisgned to improve medical practice, and these attempts have been placed in Volume II. The Background and recent advances presented here are intended to stimulate further experimentation and new innovations, and spur clinical trials by all investigators with an interest in steroid hormones, cell biology, and clinical oncology.
Steroid Hormone Receptors
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Author : V. K. Moudgil
language : en
Publisher:
Release Date : 1994
Steroid Hormone Receptors written by V. K. Moudgil and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994 with categories.
Steroid Hormones And Cell Cycle Regulation
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Author : Kerry L. Burnstein
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-11
Steroid Hormones And Cell Cycle Regulation written by Kerry L. Burnstein and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-11 with Medical categories.
From the tissue culture dish to genetically modified mice, this volume explores the long recognized role of steroid hormones in regulating cell proliferation and differentiation. Many striking effects of steroid hormones are apparent during development and neoplasia and these topics are covered extensively. Several chapters address the pharmacological uses of steroid and related hormones, their analogs and antagonists in controlling growth of endocrine cancers. This book also highlights the complex role of cross talk between steroid hormones and signals initiated at the cell surface in the regulation of cell cycle in hormone responsive tissues.