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Structural Propensities


Structural Propensities
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Structural Propensities


Structural Propensities
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Author : Monika Doherty
language : en
Publisher: John Benjamins Publishing
Release Date : 2006-01-01

Structural Propensities written by Monika Doherty and has been published by John Benjamins Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-01-01 with Language Arts & Disciplines categories.


This book focuses on the translation of English academic texts into German, closely analysing the structural and discourse properties of original sentences and their possible translations. It consists of six chapters, with more than a hundred carefully discussed examples, and presents the author s results of a series of research projects which have successively dealt with the typologically determined conditions for discourse-appropriate uses of word order, case, voice (perspective) and structural explicitness in simple and complex sentences or sequences of sentences. The theoretical and methodological assumptions of the book follow a basically generative approach in studying the interaction between semantic-pragmatic and phonological-syntactic properties of the linguistic forms as they are involved in the perception of written language. The linguistic and psycholinguistic models accessed are also introduced in detail to promote comprehension for the interested reader with an alternative theoretical background, whether scholar, student or translator.



Structural Propensities Of Short Peptides Through Molecular Dynamics Simulations


Structural Propensities Of Short Peptides Through Molecular Dynamics Simulations
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Author : Oliver Bignucolo
language : en
Publisher:
Release Date : 2012

Structural Propensities Of Short Peptides Through Molecular Dynamics Simulations written by Oliver Bignucolo and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with categories.




Structural Propensities


Structural Propensities
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Author : Monika Doherty
language : en
Publisher: John Benjamins Publishing
Release Date : 2006-04-27

Structural Propensities written by Monika Doherty and has been published by John Benjamins Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-04-27 with Language Arts & Disciplines categories.


This book focuses on the translation of English academic texts into German, closely analysing the structural and discourse properties of original sentences and their possible translations. It consists of six chapters, with more than a hundred carefully discussed examples, and presents the author’s results of a series of research projects which have successively dealt with the typologically determined conditions for discourse-appropriate uses of word order, case, voice (perspective) and structural explicitness in simple and complex sentences or sequences of sentences. The theoretical and methodological assumptions of the book follow a basically generative approach in studying the interaction between semantic-pragmatic and phonological-syntactic properties of the linguistic forms as they are involved in the perception of written language. The linguistic and psycholinguistic models accessed are also introduced in detail to promote comprehension for the interested reader with an alternative theoretical background, whether scholar, student or translator.



Studies Of Secondary Structural Propensities And Hydrophobic Clustering In The Alpha Helical Model Coiled Coil


Studies Of Secondary Structural Propensities And Hydrophobic Clustering In The Alpha Helical Model Coiled Coil
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Author : Stanley Chun Ho Kwok
language : en
Publisher:
Release Date : 2004

Studies Of Secondary Structural Propensities And Hydrophobic Clustering In The Alpha Helical Model Coiled Coil written by Stanley Chun Ho Kwok and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Amino acid sequence categories.




The Gulf Conflict And International Relations


The Gulf Conflict And International Relations
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Author : Ken Matthews
language : en
Publisher: Routledge
Release Date : 2003-12-16

The Gulf Conflict And International Relations written by Ken Matthews and has been published by Routledge this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-12-16 with History categories.


Key documents and essential facts, combined with a strong theoretical framework - this new textbook clarifies the Gulf War of 1991, puts it in the context of the changing international order and identifies long-term consequences.



The Social Origins Of Democratic Collapse


The Social Origins Of Democratic Collapse
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Author : Kathleen Crowley Schwartzman
language : en
Publisher:
Release Date : 1989

The Social Origins Of Democratic Collapse written by Kathleen Crowley Schwartzman and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1989 with Business & Economics categories.


Schwartzman's study of the first Portuguese republic demonstrates the significant ways in which a nation's social and political structures are shaped by its position in the global economy.



From Protein Structure To Function With Bioinformatics


From Protein Structure To Function With Bioinformatics
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Author : Daniel John Rigden
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-12-11

From Protein Structure To Function With Bioinformatics written by Daniel John Rigden and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-12-11 with Science categories.


Proteins lie at the heart of almost all biological processes and have an incredibly wide range of activities. Central to the function of all proteins is their ability to adopt, stably or sometimes transiently, structures that allow for interaction with other molecules. An understanding of the structure of a protein can therefore lead us to a much improved picture of its molecular function. This realisation has been a prime motivation of recent Structural Genomics projects, involving large-scale experimental determination of protein structures, often those of proteins about which little is known of function. These initiatives have, in turn, stimulated the massive development of novel methods for prediction of protein function from structure. Since model structures may also take advantage of new function prediction algorithms, the first part of the book deals with the various ways in which protein structures may be predicted or inferred, including specific treatment of membrane and intrinsically disordered proteins. A detailed consideration of current structure-based function prediction methodologies forms the second part of this book, which concludes with two chapters, focusing specifically on case studies, designed to illustrate the real-world application of these methods. With bang up-to-date texts from world experts, and abundant links to publicly available resources, this book will be invaluable to anyone who studies proteins and the endlessly fascinating relationship between their structure and function.



Pacific Symposium On Biocomputing 96


Pacific Symposium On Biocomputing 96
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Author :
language : en
Publisher: World Scientific
Release Date : 1995

Pacific Symposium On Biocomputing 96 written by and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995 with Biology categories.


"The first Pacific Symposium on Biocomputing (PSB), will be held January 3-6, 1996 at the Ritz Carlton Hotel on the Big Island of Hawaii. PSB will bring together top researchers from North America, the Asian Pacific nations, Europe, and around the world, to exchange research results and address open issues in all aspects of computational biology. Replacing and extending the last three years of Biotechnology Computing Tracks at the Hawaiian International Conference on System Sciences, PSB will provide a forum for the presentation of work in databases, algorithms, interfaces, visualization, modelling and other computational methods, as applied to biological problems, with emphasis on applications in data-rich areas of molecular biology. The PSB is focussed into 4 tracks, 4 minitracks, 2 workshops and includes two invited keynote speakers, viz., Logical Simulation of Biomolecular Information Pathways (Minoru Kanehisa, Kyoto Univ.) and CEX and the Single Chemist (David Weimger, DAYLIGHT Chemical Info. Syst.)"--Publisher's website.



Unfolded Proteins


Unfolded Proteins
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Author : Trevor P. Creamer
language : en
Publisher: Nova Publishers
Release Date : 2008

Unfolded Proteins written by Trevor P. Creamer and has been published by Nova Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with Science categories.


The word revolution has a number of definitions (The American Heritage Dictionary, 2006). The one most pertinent to this series and volume is 'a sudden or momentous change in a situation'. Recent years have seen an unprecedented explosion of interest in unfolded proteins in all of their various forms. Coupled with this increase in interest we have seen momentous changes in the way unfolded proteins are viewed. Two particular paradigms have come under close scrutiny: unfolded proteins are disordered random coils devoid of persistent structure, and protein function first requires protein structure. The first of these is currently a hotly debated subject. The second paradigm we can safely claim has been overturned. There is a second definition of revolution that is quite relevant to a significant portion of the work reviewed herein, in particular those chapters dealing with local and persistent structure in unfolded proteins. That definition is 'a turning or rotational motion about an axis' (The American Heritage Dictionary, 2006). About four decades ago, Charles Tanford (1968) demonstrated that highly denatured proteins possess hydrodynamic properties consistent with Paul Flory's random coil (Flory, 1969). Given that the Flory random coil definition included the stipulation that conformers making up the denatured state ensemble would differ in energy by just a few kT, there has been the assumption that denatured states must therefore be completely random in nature with no persistent structure or biases towards particular conformers. Notably however, Tanford did note the random coil-like hydrodynamic data he obtained did not necessarily rule out the presence of structure in denatured proteins (Tanford, 1968). Around the same time, Sam Krimm and M. Lois Tiffany noted that the CD spectra they obtained for proteins in the presence of high concentration of chemical denaturants had similarities to spectra obtained for homopolymers of proline, lysine, and glutamic acid in water (Tiffany and Krimm, 1968a, 1968b, 1973, 1974). Homopolymers of these residues were known to adopt the left-handed polyproline II conformation, leading Tiffany and Krimm to hypothesise that highly denatured proteins possess significant polyproline II helix content. Of these two views, that espousing the lack of structure in denatured proteins became more widely adopted and was, over time, adopted as a central paradigm in protein folding. As several of the chapters in this volume note, a Tiffany and Krimm-like view appears to be, to some extent, the more correct one. The level to which it is correct is still unknown, although it is clear that the polyproline II helical conformation is not the only, perhaps not even the most common, persistent conformation present in unfolded proteins. Thus we have come through a full circle or revolution. (from the preface)



In Cell Nmr Spectroscopy


In Cell Nmr Spectroscopy
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Author : Alexander Shekhtman
language : en
Publisher: MDPI
Release Date : 2020-04-30

In Cell Nmr Spectroscopy written by Alexander Shekhtman and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-04-30 with Science categories.


This Special Issue examines state-of-the-art in-cell NMR spectroscopy as it relates to biological systems of increasing complexity. The compendia of research and recent innovations from prominent laboratories in the field of solid state and solution in-cell NMR spectroscopy, metabolomics and technology development are presented. The work establishes in-cell NMR spectroscopy as the premier method for determining the structures and interaction capabilities of biological molecules at high resolution within the delicately intricate interior of living cells, and the means of utilizing cells as living laboratories to directly assess the effects of exogenous and endogenous stimuli on cell physiology.]