Structure And Function Of The Extracellular Matrix

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Composition And Function Of The Extracellular Matrix In The Human Body
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Author : Francesco Travascio
language : en
Publisher: BoD – Books on Demand
Release Date : 2016-06-15
Composition And Function Of The Extracellular Matrix In The Human Body written by Francesco Travascio and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-06-15 with Science categories.
The extracellular matrix (ECM) is an ensemble of non-cellular components present within all tissues and organs of the human body. The ECM provides structural support for scaffolding cellular constituents and biochemical and biomechanical support for those events leading to tissue morphogenesis, differentiation and homeostasis. Essential components of all ECMs are water, proteins and polysaccharides. However, their composition, architecture and bioactivity greatly vary from tissue to tissue in relation to the specific role the ECM is required to assume. This book overviews the role of the ECM in different tissues and organs of the human body.
Molecular Biology Of The Cell
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Author :
language : en
Publisher:
Release Date : 2004
Molecular Biology Of The Cell written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Cells categories.
Cell Biology Of Extracellular Matrix
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Author : E.D. Hay
language : en
Publisher: Springer Science & Business Media
Release Date : 1991-12-31
Cell Biology Of Extracellular Matrix written by E.D. Hay and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991-12-31 with Science categories.
In the ten-year interval since the first edition of this volume went to press, our knowledge of extracellular matrix (ECM) function and structure has enor mously increased. Extracellular matrix and cell-matrix interaction are now routine topics in the meetings and annual reviews sponsored by cell biology societies. Research in molecular biology has so advanced the number of known matrix molecules and the topic of gene structure and regulation that we won dered how best to incorporate the new material. For example, we deliberated over the inclusion of chapters on molecular genetics. We decided that with judicious editing we could present the recent findings in molecular biology within the same cell biology framework that was used for the first edition, using three broad headings: what is extracellular matrix, how is it made, and what does it do for cells? Maintaining control over the review of literature on the subject of ECM was not always an easy task, but we felt it was essential to production of a highly readable volume, one compact enough to serve the the student as an introduction and the investigator as a quick update on graduate the important recent discoveries. The first edition of this volume enjoyed con hope the reader finds this edition equally useful. siderable success; we D. Hay Elizabeth vii Contents Introductory Remarks 1 Elizabeth D. Hay PART I. WHAT IS EXTRACELLULAR MATRIX? Chapter 1 Collagen T. F. Linsenmayer 1. Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7 2. The Collagen Molecule . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8 2. 1. Triple-Helical Domain(s) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Mimicking The Extracellular Matrix
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Author : Gregory H. Hudalla
language : en
Publisher: Royal Society of Chemistry
Release Date : 2015-11-18
Mimicking The Extracellular Matrix written by Gregory H. Hudalla and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-11-18 with Medical categories.
Mimicking the Extracellular Matrix approaches this topic from both basic science and practical engineering perspectives. Suitable for undergraduates, postgraduates, and academics, this text aims to unify the current knowledge of ECM biology and matrix-mimicking biomaterials.
The Collagen Superfamily And Collagenopathies
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Author : Florence Ruggiero
language : en
Publisher: Springer Nature
Release Date : 2021-05-15
The Collagen Superfamily And Collagenopathies written by Florence Ruggiero and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-05-15 with Science categories.
This book aims at providing insights into the collagen superfamily and the remarkable diversity of collagen function within the extracellular matrix. Additionally, the mechanisms underlying collagen-related diseases such as dystrophic epidermolysis bullosa, osteogenesis imperfecta, as well as collagen-related myopathies and neurological disorders are discussed. Collagens are the most abundant extracellular matrix proteins in organisms. Their primary function is to provide structural support and strength to cells and to maintain biomechanical integrity of tissues. However, collagens can no longer be considered just as structural proteins. They can act as extracellular modulators of signaling events and serve critical regulatory roles in various cell functions during embryonic development and adult homeostasis. Furthermore, collagens are associated with a broad spectrum of heritability-related diseases known as “collagenopathies” that affect a multitude of organs and tissues including sensorial organs. The book is a useful introduction to the field for junior scientists, interested in extracellular matrix research. It is also an interesting read for advanced scientists and clinicians working on collagens and collagenopathies, giving them a broader view of the field beyond their area of specialization.
Tissue Regeneration
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Author : Hussein Abdel hay El-Sayed Kaoud
language : en
Publisher:
Release Date : 2018
Tissue Regeneration written by Hussein Abdel hay El-Sayed Kaoud and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018 with Medicine (General) categories.
Tissue regeneration is a vast subject, with many different important aspects to consider. Regenerative medicine is a new branch of medicine that tries to change the course of chronic diseases and, in many cases, regenerates the organ systems that fail due to age, disease, damage, or genetic defects. The main purpose of this book is to point out the interest of some important topics of tissue regeneration and the progress in this field as well as the variety of different surgical fields and operations. This book includes 7 sections and 11 chapters that provide an overview of the essentials in tissue regeneration science and their potential applications in surgery. The authors of each chapter have given consolidated information on ground realities and attempted to provide a comprehensive knowledge of tissue engineering and regeneration. This book will be useful to researchers and students of biological and biomedical sciences (medical and veterinarian researchers).
Postgraduate Orthopaedics
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Author : Paul A. Banaszkiewicz
language : en
Publisher: Cambridge University Press
Release Date : 2012-08-16
Postgraduate Orthopaedics written by Paul A. Banaszkiewicz and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-08-16 with Medical categories.
The must-have book for candidates preparing for the oral component of the FRCS (Tr and Orth).
Microbial Extracellular Polymeric Substances
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Author : Jost Wingender
language : en
Publisher: Springer Science & Business Media
Release Date : 1999-10-20
Microbial Extracellular Polymeric Substances written by Jost Wingender and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999-10-20 with Science categories.
Microbial extracellular polymeric substances (EPS) are the key components for the aggregation of microorganisms in biofilms, flocs and sludge. They are composed of polysaccharides, proteins, nucleic acids, lipids and other biological macromolecules. EPS provide a highly hydrated gel matrix in which microbial cells can establish stable synergistic consortia. Cohesion and adhesion as well as morphology, structure, biological function and other properties such as mechanical stability, diffusion, sorption and optical properties of microbial aggregates are determined by the EPS matrix. Also, the protection of biofilm organisms against biocides is attributed to the EPS. Their matrix allows phase separation in biofiltration and is also important for the degradation of particulate material which is of great importance for the self purification processes in surface waters and for waste water treatment. In this volume, analysis, characterization, composition, regulation, function and interactions of microbial EPS are covered.
Structure And Function Of Collagen Types
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Author : Richard Maynes
language : en
Publisher: Elsevier
Release Date : 2012-12-02
Structure And Function Of Collagen Types written by Richard Maynes and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Science categories.
Structure and Function of Collagen Types is a collection of articles that reviews the different types of collagens (Type I to XI). Each article focuses on a particular type of collagen and written by leading investigators in the collagen field. The book begins with a review of the fibril forming collagens (types I, II, and III) and traces the early work on the structure of these collagens to our knowledge of the structure of the collagen genes. This chapter is followed by a detailed description of type IV (basement membrane) collagen. Chapter 3 addresses the biosynthesis and chain assembly of type V collagen. The evidence that type VI collagen is assembled to form tetramers is presented in chapter 4. The subsequent article shows that type VII collagens are assembled to form partially overlapping dimers. Chapter 6 presents the structure of type VIII collagen. Chapters 7, 8, and 9 discuss the structure and characteristics of collagens that are synthesized by cartilaginous tissues and these are designated as type IX, type X, and type XI. The final chapter reviews the recombinant DNA techniques used to investigate collagen structure and the possibility to recognize new collagen types from a cDNA library. Physiologists, cell biologists, and researchers in the field of collagen will find the text very insightful.
Collagen
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Author : Peter Fratzl
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-05-10
Collagen written by Peter Fratzl and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-05-10 with Technology & Engineering categories.
Collagen: Structure and Mechanics provides a cohesive introduction to this biological macromolecule and its many applications in biomaterials and tissue engineering. Graduate students and postdoctoral researchers in the fields of materials, (bio-)engineering, physics, chemistry and biology will gain an understanding of the structure and mechanical behavior of type I collagen and collagen-based tissues in vertebrates, across all length scales from the molecular (nano) to the organ (macro) level. Written in a clear and didactic manner, this volume includes current knowledge on the hierarchical structure, mechanical properties, in addition to a review of deformation and strengthening mechanisms. Collagen: Structure and Mechanics is an excellent reference for new researchers entering this area and serves as a basis for lecturing in the interdisciplinary field of biological materials science.