Synthesis Of Naturally Occurring Nitrogen Heterocycles From Carbohydrates
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Synthesis Of Naturally Occurring Nitrogen Heterocycles From Carbohydrates
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Author : El Sayed H. El Ashry
language : en
Publisher: John Wiley & Sons
Release Date : 2008-04-15
Synthesis Of Naturally Occurring Nitrogen Heterocycles From Carbohydrates written by El Sayed H. El Ashry and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-04-15 with Science categories.
Carbohydrates are widely distributed in nature and widely available, and so are considered as a promising feedstock for the preparation of many organic chemical compounds. They are particularly useful in the preparation of nitrogen heterocycles because of their related structural characteristics and easy availability. Synthesis of Naturally Occurring Nitrogen Heterocycles from Carbohydrates will review the recent literature dealing with use of carbohydrates as raw materials in the synthesis of these materials. The text contains six chapters arranged according to the complexity of the heterocyclic compounds discussed, ranging from five to seven membered rings and from single to multiple fused rings. The book provides a detailed discussion of the various synthetic approaches to these compounds, using carbohydrate starting materials, and does not merely reference synthetic methodology but attempts to give as much detail as possible on the actual experimental conditions used, in such a way that the chemist can use the information directly to design a multi-step synthesis. It discusses the different approaches to the synthesis of a wide range of naturally occurring nitrogen heterocycles in a format that enables the reader to make comparisons and decisions on whether to use a certain procedure, to modify it, or to devise a new synthetic methodology.
Carbohydrates As Drugs
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Author : Peter H. Seeberger
language : en
Publisher: Springer
Release Date : 2014-11-14
Carbohydrates As Drugs written by Peter H. Seeberger and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-11-14 with Science categories.
Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry. Drug research requires interdisciplinary team-work at the interface between chemistry, biology and medicine. Therefore, the topic-related series Topics in Medicinal Chemistry covers all relevant aspects of drug research, e.g. pathobiochemistry of diseases, identification and validation of (emerging) drug targets, structural biology, drugability of targets, drug design approaches, chemogenomics, synthetic chemistry including combinatorial methods, bioorganic chemistry, natural compounds, high-throughput screening, pharmacological in vitro and in vivo investigations, drug-receptor interactions on the molecular level, structure-activity relationships, drug absorption, distribution, metabolism, elimination, toxicology and pharmacogenomics. In general, special volumes are edited by well known guest editors.
Advances In Heterocyclic Chemistry
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Author : Alan R. Katritzky
language : en
Publisher: Academic Press
Release Date : 2011-01-07
Advances In Heterocyclic Chemistry written by Alan R. Katritzky and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-01-07 with Science categories.
Established in 1960, Advances in Heterocyclic Chemistry is the definitive serial in the area-one of great importance to organic chemists, polymer chemists, and many biological scientists. Written by established authorities in the field, the comprehensive reviews combine descriptive chemistry and mechanistic insight and yield an understanding of how the chemistry drives the properties. Provides up-to-date material on a fast-growing and highly topical subject area Contains the latest research covering a wide variety of heterocyclic topics Written by leading authorities and designed as a handbook for students and industry and academic researchers
Recent Trends In Carbohydrate Chemistry
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Author : Amélia Pilar Rauter
language : en
Publisher: Elsevier
Release Date : 2020-04-27
Recent Trends In Carbohydrate Chemistry written by Amélia Pilar Rauter and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-04-27 with Science categories.
Carbohydrate chemistry provides access to carbohydrate-based natural products and synthetic molecules as useful biologically active structures relevant to many health care and disease-related biological processes. Recent Trends in Carbohydrate Chemistry: Synthesis, Structure, and Function of Carbohydrates covers green and sustainable reactions, organometallic carbohydrate chemistry, synthesis of glycomimetics, multicomponent reactions, and chemical transformations leading to molecular diversity based on carbohydrates. These include inhibitors of glycogen phosphorylase, which are relevant in controlling type 2 diabetes and sugar sulfates. Polysaccharides, which are commonly modified chemically, are also examined with contributions covering polysaccharide synthesis and modification of polysaccharides to obtain new structures and properties. Recent Trends in Carbohydrate Chemistry: Synthesis, Structure, and Function of Carbohydrates is ideal for researchers working as synthetic organic chemists, and for those interested in biomolecular chemistry, green chemistry, organometallic chemistry, and material chemistry in academia as well as in industry Demonstrates the importance of carbohydrate chemistry as green and sustainable chemistry Details monosaccharide syntheses and transformations toward biologically active small molecular entities Provides the most recent findings on polysaccharide synthesis and bioapplications
Advances In Carbohydrate Chemistry And Biochemistry
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Author :
language : en
Publisher: Academic Press
Release Date : 2011-09-09
Advances In Carbohydrate Chemistry And Biochemistry written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-09-09 with Science categories.
Since its inception in 1945, this serial has provided critical and integrating articles written by research specialists that integrate industrial, analytical, and technological aspects of biochemistry, organic chemistry, and instrumentation methodology in the study of carbohydrates. The articles provide a definitive interpretation of the current status and future trends in carbohydrate chemistry and biochemistry. Features contributions from leading authorities and industry experts Informs and updates on all the latest developments in the field
Heterocycles From Carbohydrate Precursors
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Author : El Sayed H. El Ashry
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-07-30
Heterocycles From Carbohydrate Precursors written by El Sayed H. El Ashry and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-07-30 with Science categories.
With contributions by numerous experts
Domino And Intramolecular Rearrangement Reactions As Advanced Synthetic Methods In Glycoscience
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Author : Zbigniew J. Witczak
language : en
Publisher: John Wiley & Sons
Release Date : 2016-01-07
Domino And Intramolecular Rearrangement Reactions As Advanced Synthetic Methods In Glycoscience written by Zbigniew J. Witczak and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-01-07 with Science categories.
The book consists of a brief introduction, a foreward provided by professor Danishefsky of Columbia University, and about 14 - 16 chapters, each written by one or two eminent scholars/authors describing their recent research in the area of either domino reactions or intramolecular rearrangements in carbohydrate chemistry. Three or four chapters will be reviews. The domino (cascade, tandem) reactions are always intramolecular. They are usually very fast, clean and offer highly complex structures in a one pot process. Intramolecular rearrangements offer very similar advantages and often lead to highly complex products as well. Although many recently isolated carbohydrates fulfill various sophisticated functions, their structures are often very complex. The editors cover the broadest scope of novel methodologies possible. All the synthetic and application aspects of domino/cascade reactions are explored in this book. A second theme that will be covered is intramolecular rearrangement, which is also fast, stereoselective, and often constitutes one or more steps of domino / cascade process. Selected examples of intramolecular rearrangements are presented. Together, both processes offer an elegant and convenient approach to the synthesis of many complex molecules, which are normally difficult to synthesize via alternative routes. It appears that domino and intramolecular rearrangements are ideally suited to synthesize certain specific modified monosaccharides. What is particularly important is that both processes are intermolecular and almost always yield products with very well-defined stereochemistry. This high definition is absolutely crucial when synthesizing advanced, modified mono and oligosaccharides. The choice of contributors reflects an emphasis on both therapeutic and pharmacological aspects of carbohydrate chemistry.
Metal Free C H Functionalization Of Aromatics
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Author : Valery Charushin
language : en
Publisher: Springer
Release Date : 2014-09-03
Metal Free C H Functionalization Of Aromatics written by Valery Charushin and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-09-03 with Science categories.
The series Topics in Heterocyclic Chemistry presents critical reviews on present and future trends in the research of heterocyclic compounds. Overall the scope is to cover topics dealing with all areas within heterocyclic chemistry, both experimental and theoretical, of interest to the general heterocyclic chemistry community. The series consists of topic related volumes edited by renowned editors with contributions of experts in the field.
Heterocyclic Chemistry
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Author : John A. Joule
language : en
Publisher: John Wiley & Sons
Release Date : 2013-05-28
Heterocyclic Chemistry written by John A. Joule and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-05-28 with Science categories.
This book has so closely matched the requirements of its readership over the years that it has become the first choice for chemists worldwide. Heterocyclic chemistry comprises at least half of all organic chemistry research worldwide. In particular, the vast majority of organic work done in the pharmaceutical and agrochemical industries is heterocyclic chemistry. The fifth edition of Heterocyclic Chemistry maintains the principal objective of earlier editions – to teach the fundamentals of heterocyclic reactivity and synthesis in a way that is understandable to second- and third-year undergraduate chemistry students. The inclusion of more advanced and current material also makes the book a valuable reference text for postgraduate taught courses, postgraduate researchers, and chemists at all levels working with heterocyclic compounds in industry. Fully updated and expanded to reflect important 21st century advances, the fifth edition of this classic text includes the following innovations: Extensive use of colour to highlight changes in structure and bonding during reactions Entirely new chapters on organometallic heterocyclic chemistry, heterocyclic natural products, especially in biochemical processes, and heterocycles in medicine New sections focusing on heterocyclic fluorine compounds, isotopically labeled heterocycles, and solid-phase chemistry, microwave heating and flow reactors in the heterocyclic context Essential teaching material in the early chapters is followed by short chapters throughout the text which capture the essence of heterocyclic reactivity in concise resumés suitable as introductions or summaries, for example for examination preparation. Detailed, systematic discussions cover the reactivity and synthesis of all the important heterocyclic systems. Original references and references to reviews are given throughout the text, vital for postgraduate teaching and for research scientists. Problems, divided into straightforward revision exercises, and more challenging questions (with solutions available online), help the reader to understand and apply the principles of heterocyclic reactivity and synthesis.
Progress In Medicinal Chemistry
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Author :
language : en
Publisher: Elsevier
Release Date : 2011-02-09
Progress In Medicinal Chemistry written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-02-09 with Medical categories.
Progress in Medicinal Chemistry provides a review of eclectic developments in medicinal chemistry. This volume continues in the serial's tradition of providing an insight into the skills required of the modern medicinal chemist; in particular, the use of an appropriate selection of the wide range of tools now available to solve key scientific problems. Presents the latest research in the field of drug discovery Publishes on a twice yearly basis to bring you the most innovative updates in medicinal chemistry Available as an online resource via ScienceDirect