Targeted
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Targeted Drug Delivery
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Author : Yogeshwar Bachhav
language : en
Publisher: John Wiley & Sons
Release Date : 2022-10-24
Targeted Drug Delivery written by Yogeshwar Bachhav and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-10-24 with Science categories.
Targeted Drug Delivery Novel approaches in targeted drug delivery for both small molecule and biopharmaceutical drugs Targeted Drug Delivery explores a new frontier in drug research that has become a focus for developing novel medications. The work discusses a wide range of approaches for targeting small molecules as well as peptide and macromolecular drugs, from prodrugs to drug conjugates to drug carriers and devices, helping readers to stay up to date on the latest developments in the field. The following key topics are addressed: Antibody conjugates, prodrugs, and suicide gene therapeutics Protac technology for selectively degrading target proteins Delivery of nucleic acid drugs Novel drug carriers, such as liposomes, vesicles, and nanoparticles Unmet medical needs for which there is a large market potential, such as viral infections and cancer For chemists, pharmacologists, and professionals in the wider pharmaceutical industry, Targeted Drug Delivery is a comprehensive guide on how to solve the greatest challenge in treating many diseases: delivering a pharmaceutically active substance to the target tissue in the body.
Targeted Killings
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Author : Claire Finkelstein
language : en
Publisher: OUP Oxford
Release Date : 2012-03-01
Targeted Killings written by Claire Finkelstein and has been published by OUP Oxford this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-03-01 with Law categories.
The war on terror is remaking conventional warfare. The protracted battle against a non-state organization, the demise of the confinement of hostilities to an identifiable battlefield, the extensive involvement of civilian combatants, and the development of new and more precise military technologies have all conspired to require a rethinking of the law and morality of war. Just war theory, as traditionally articulated, seems ill-suited to justify many of the practices of the war on terror. The raid against Osama Bin Laden's Pakistani compound was the highest profile example of this strategy, but the issues raised by this technique cast a far broader net: every week the U.S. military and CIA launch remotely piloted drones to track suspected terrorists in hopes of launching a missile strike against them. In addition to the public condemnation that these attacks have generated in some countries, the legal and moral basis for the use of this technique is problematic. Is the U.S. government correct that nations attacked by terrorists have the right to respond in self-defense by targeting specific terrorists for summary killing? Is there a limit to who can legitimately be placed on the list? There is also widespread disagreement about whether suspected terrorists should be considered combatants subject to the risk of lawful killing under the laws of war or civilians protected by international humanitarian law. Complicating the moral and legal calculus is the fact that innocent bystanders are often killed or injured in these attacks. This book addresses these issues. Featuring chapters by an unrivalled set of experts, it discusses all aspects of targeted killing, making it unmissable reading for anyone interested in the implications of this practice.
Drones And The Ethics Of Targeted Killing
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Author : Kenneth R. Himes, OFM
language : en
Publisher: Bloomsbury Publishing PLC
Release Date : 2015-09-03
Drones And The Ethics Of Targeted Killing written by Kenneth R. Himes, OFM and has been published by Bloomsbury Publishing PLC this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-09-03 with Religion categories.
Drones have become an essential part of U.S. national security strategy, but most Americans know little about how they are used, and we receive conflicting reports about their outcomes. In Drones and the Ethics of Targeted Killing, ethicist Kenneth R. Himes provides not only an overview of the role of drones in national security but also an important exploration of the ethical implications of drone warfare—from the impact on terrorist organizations and civilians to how piloting drones shapes soldiers. Targeted killings have played a role in politics from ancient times through today, so the ethical challenges around how to protect against threats are not new. Himes leads readers through the ethics of targeted killings in history from ancient times to the contemporary Israeli-Palestinian conflict, then looks specifically at the new issues raised through the use of drones. This book is a powerful look at a pressing topic today.
Nanotechnology Based Approaches For Targeting And Delivery Of Drugs And Genes
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Author : Vijay Mishra
language : en
Publisher: Academic Press
Release Date : 2017-05-23
Nanotechnology Based Approaches For Targeting And Delivery Of Drugs And Genes written by Vijay Mishra and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-05-23 with Medical categories.
Nanotechnology-Based Approaches for Targeting and Delivery of Drugs and Genes provides an overview of the important aspects of nanomedicine in order to illustrate how to design and develop novel and effective drug delivery systems using nanotechnology. The book is organized into three sections, beginning with an introduction to nanomedicine and its associated issues. Section two discusses the latest technologies in nanomedicine, while the third section covers future developments and challenges in the field. By focusing on the design, synthesis, and application of a variety of nanocarriers in drug and gene delivery, this book provides pharmaceutical and materials science students, professors, clinical researchers, and industry scientists with a valuable resource aimed at tackling the challenges of delivering drugs and genes in a more targeted manner. - Explores a wide range of promising approaches for the diagnosis and treatment of diseases using the latest advances in cutting-edge nanomedical technologies - Contains contributions from world-renowned experts and researchers working in the area of nanomedicine and drug delivery - Covers the associated challenges and potential solutions to working with nanotechnology in drug delivery - Highlights crucial topics, such as biopharmaceutical and toxicity issues, quality by design, drug targeting, and more
Handbook Of Targeted Delivery Of Imaging Agents
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Author : Vladimir P. Torchilin
language : en
Publisher: CRC Press
Release Date : 1995-08-23
Handbook Of Targeted Delivery Of Imaging Agents written by Vladimir P. Torchilin and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995-08-23 with Medical categories.
This is the first time detailed and updated information on the targeted delivery of imaging agents has been collected into a single handbook. This comprehensive volume presents the scientific background together with the latest experimental and clinical data in this fast-growing area. The Handbook of Targeted Delivery of Imaging Agents meets the requirements of the broadest audience including researchers, practitioners, and students. The basic principles of targeted delivery of imaging are presented and discussed together with various imaging agents and different imaging modalities such as gamma-imaging, MR-imaging, and CT, PET, and SPECT imaging. The book consists of eight parts and 39 chapters covering all aspects of targeted drug delivery-from the imaging theory and chemistry of imaging agents to their experimental and clinical use for targeted visualization of cancer, including ovarian, prostate, colorectal, and thyroid cancer, cardiovascular (atherosclerosis, myocardial infarction, and thromboses) and neurological diseases, infection, and inflammation sites. A special section discusses the targeted delivery of imaging agents into lymph nodes, which are often sites of metasteses during different malignant diseases. Monoclonal antibody-based targeted imaging agents are considered together with new approaches involving the use of labeled micelles, liposomes, and polymer-coated particles. The book describes the possible application of designer antibodies for the delivery of diagnostic agents, including the preparation, properties, labeling, and experimental use of multifunctional antibodies. The alternative improvement of antibody-directed targeting describes the application of avidin-biotin system for the delivery of imaging agents. Long circulating blood pool imaging agents are considered as a special group of organ-specific pharmaceuticals. The latest trends in the synthesis of immunoscintigraphic, MR, and CT agents are presented. This Handbook of Targeted Delivery of Imaging Agents is a must-have reference for all those who need to stay abreast of the latest developments in this hot field.
Nanotechnology Based Targeted Drug Delivery Systems For Brain Tumors
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Author : Prashant Kesharwani
language : en
Publisher: Academic Press
Release Date : 2018-04-20
Nanotechnology Based Targeted Drug Delivery Systems For Brain Tumors written by Prashant Kesharwani and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-04-20 with Medical categories.
Nanotechnology-Based Targeted Drug Delivery Systems for Brain Tumors addresses brain anatomy and tumors and the progress and challenges in delivering drugs across the blood brain barrier. Several chapters are devoted to the latest technologies and advances in nanotechnology, along with practical solutions on how to design more effective nanocarriers for drug and gene delivery. This valuable resource prepares readers to develop novel drug delivery systems for the treatment of brain tumors that further promote the latest nanomedical technologies. - Addresses the progress and challenges inherent in delivering drugs across the blood brain barrier and offers strategies to maximize effectiveness - Draws upon the experience and expertise of international scientists working in the fields of drug delivery and nanomedicine - Considers the future possibilities of nanotechnology for delivering nanocarriers that better diagnose and treat brain tumors
Advances In Targeted Cancer Therapy
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Author : Richard M. Schultz
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-01-24
Advances In Targeted Cancer Therapy written by Richard M. Schultz and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-01-24 with Medical categories.
There have been tremendous advances in our understanding of molecular and tumor biology during the past few years. In the field of cancer therapeutics, it is expected that cytotoxic drug approaches will be gradually replaced with treatments based on biological targeted approaches. Hopefully these new targeted therapies will significantly increase efficacy and lack the devastating and troublesome side effects elicited by cytotoxic chemotherapy. This volume is the first book to cover the general topic of targeted cancer therapy. It presents a range of targets such as tumor angiogenesis, cell cycle control and cell signalling, COX-2, apoptosis/cell survival, invasion and metastasis and approaches like kinase inhibitors, antisense, and antibody-based therapeutics. The emphasis is on preclinical development, including target validation, development of biomarkers, strategies for combination approaches, and development of resistance. The particular challenges involved in translating these data to clinical application are discussed. This volume should be of broad general interest to researchers and clinicians involved in cancer therapy as well as other scientists interested in current strategies for cancer treatment.
Handbook Of Lung Targeted Drug Delivery Systems
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Author : Yashwant Pathak
language : en
Publisher: CRC Press
Release Date : 2021-10-17
Handbook Of Lung Targeted Drug Delivery Systems written by Yashwant Pathak and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-10-17 with Medical categories.
Handbook of Lung Targeted Drug Delivery Systems: Recent Trends and Clinical Evidences covers every aspect of the drug delivery to lungs, the physiology and pharmacology of the lung, modelling for lung delivery, drug devices focused on lung treatment, regulatory requirements, and recent trends in clinical applications. With the advent of nano sciences and significant development in the nano particulate drug delivery systems there has been a renewed interest in the lung as an absorption surface for various drugs. The emergence of the COVID-19 virus has brought lung and lung delivery systems into focus, this book covers new developments and research used to address the prevention and treatment of respiratory diseases. Written by well-known scientists with years of experience in the field this timely handbook is an excellent reference book for the scientists and industry professionals. Key Features: Focuses particularly on the chemistry, clinical pharmacology, and biological developments in this field of research. Presents comprehensive information on emerging nanotechnology applications in diagnosing and treating pulmonary diseases Explores drug devices focused on lung treatment, regulatory requirements, and recent trends in clinical applications Examines specific formulations targeted to pulmonary systems
The Oxford Handbook Of Adolescent Substance Abuse
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Author : Robert A. Zucker
language : en
Publisher: Oxford University Press
Release Date : 2019-08-01
The Oxford Handbook Of Adolescent Substance Abuse written by Robert A. Zucker and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-08-01 with Psychology categories.
Adolescent substance abuse is the nation's #1 public health problem. It originates out of a developmental era where experimentation with the world is increasingly taking place, and where major changes in physical self and social relationships are taking place. These changes cannot be understood by any one discipline nor can they be described by focusing only on the behavioral and social problems of this age period, the characteristics of normal development, or the pharmacology and addictive potential of specific drugs. They require knowledge of the brain's systems of reward and control, genetics, psychopharmacology, personality, child development, psychopathology, family dynamics, peer group relationships, culture, social policy, and more. Drawing on the expertise of the leading researchers in this field, this Handbook provides the most comprehensive summarization of current knowledge about adolescent substance abuse. The Handbook is organized into eight sections covering the literature on the developmental context of this life period, the epidemiology of adolescent use and abuse, similarities and differences in use, addictive potential, and consequences of use for different drugs; etiology and course as characterized at different levels of mechanistic analysis ranging from the genetic and neural to the behavioural and social. Two sections cover the clinical ramifications of abuse, and prevention and intervention strategies to most effectively deal with these problems. The Handbook's last section addresses the role of social policy in framing the problem, in addressing it, and explores its potential role in alleviating it.
Targeting In Social Programs A Practical Guide
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Author : Pasquale De Marco
language : en
Publisher: Pasquale De Marco
Release Date : 2025-07-07
Targeting In Social Programs A Practical Guide written by Pasquale De Marco and has been published by Pasquale De Marco this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-07-07 with Social Science categories.
**Targeting in Social Programs: A Practical Guide** provides a comprehensive overview of the key concepts, methods, and ethical considerations involved in targeting social programs. This book is essential reading for practitioners, researchers, and policymakers who want to improve the effectiveness of their programs. It offers a clear and concise explanation of targeting, as well as practical tips and recommendations for using targeting effectively. The book begins by defining targeting and explaining its benefits and challenges. It then discusses the different methods that can be used to identify target populations, including data analysis, qualitative research, and stakeholder engagement. The book also covers the ethical and legal considerations that must be taken into account when targeting is used. The second part of the book provides a detailed overview of the different types of interventions that can be used to target social programs. It discusses the principles of intervention design, the intervention development process, and the evaluation of intervention effectiveness. The book also provides a number of case studies that illustrate how targeting has been used effectively in a variety of social programs. The final part of the book discusses the future of targeting in social programs. It explores the role of technology in targeting, the ethical implications of targeting, and the challenges of targeting in a changing world. The book concludes by offering a call to action for practitioners, researchers, and policymakers to use targeting to improve the effectiveness of social programs. **Targeting in Social Programs: A Practical Guide** is the definitive resource on targeting for social programs. It provides a comprehensive overview of the topic and offers a number of practical tips and recommendations for using targeting effectively. This book is essential reading for anyone who wants to improve the effectiveness of their social programs. If you like this book, write a review on google books!