The Search For The Gene

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The Search For The Gene

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Author : Bruce Wallace
language : en
Publisher: Cornell University Press
Release Date : 2018-05-31

The Search For The Gene written by Bruce Wallace and has been published by Cornell University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-05-31 with Science categories.

From Gregor Mendel's experiments on garden peas to the mammoth Human Genome Project of today—how did we get where we are in the science of genetics? In this intriguing book, Bruce Wallace examines the concept of the gene and recounts the history of genetic research, providing a concise transition from genetics to modern molecular biology.

Phenotypes And Genotypes

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Author : Florian Frommlet
language : en
Publisher: Springer
Release Date : 2016-02-12

Phenotypes And Genotypes written by Florian Frommlet and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-02-12 with Computers categories.

This timely text presents a comprehensive guide to genetic association, a new and rapidly expanding field that aims to elucidate how our genetic code (genotypes) influences the traits we possess (phenotypes). The book provides a detailed review of methods of gene mapping used in association with experimental crosses, as well as genome-wide association studies. Emphasis is placed on model selection procedures for analyzing data from large-scale genome scans based on specifically designed modifications of the Bayesian information criterion. Features: presents a thorough introduction to the theoretical background to studies of genetic association (both genetic and statistical); reviews the latest advances in the field; illustrates the properties of methods for mapping quantitative trait loci using computer simulations and the analysis of real data; discusses open challenges; includes an extensive statistical appendix as a reference for those who are not totally familiar with the fundamentals of statistics.

The Science Of Desire

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Author : Dean H. Hamer
language : en
Publisher:
Release Date : 1994

The Science Of Desire written by Dean H. Hamer and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994 with Science categories.

Front-page headlines last July reported the discovery of a gene marker for male homosexuality. Now the scientist who made the discovery describes his history-making research and the far-reaching implications of this first genetic link to behavior.

Decoding Darkness

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Author : Rudolph E Tanzi
language : en
Publisher: Hachette UK
Release Date : 2008-01-07

Decoding Darkness written by Rudolph E Tanzi and has been published by Hachette UK this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-01-07 with Science categories.

Working from the intriguing hypothesis that Alzheimer's dementia is the result of a renegade protein-beta amyloid-Tanzi and others set out to find the gene responsible for its production. Decoding Darkness takes us deep into the minds and far-flung labs of many a prominent researcher, offering an intimate view of the high stakes of molecular genetics, the revolution that propels it, the obstacles that threaten to derail it, and the families whose lives are so dependent upon it. Tanzi and Parson ultimately reveal that Alzheimer's, like heart disease, may be effectively treated-even prevented.

The Code Breaker

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Author : Walter Isaacson
language : en
Publisher: Simon and Schuster
Release Date : 2021-03-09

The Code Breaker written by Walter Isaacson and has been published by Simon and Schuster this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-09 with Biography & Autobiography categories.

A Best Book of 2021 by Bloomberg BusinessWeek, Time, and The Washington Post The bestselling author of Leonardo da Vinci and Steve Jobs returns with a “compelling” (The Washington Post) account of how Nobel Prize winner Jennifer Doudna and her colleagues launched a revolution that will allow us to cure diseases, fend off viruses, and have healthier babies. When Jennifer Doudna was in sixth grade, she came home one day to find that her dad had left a paperback titled The Double Helix on her bed. She put it aside, thinking it was one of those detective tales she loved. When she read it on a rainy Saturday, she discovered she was right, in a way. As she sped through the pages, she became enthralled by the intense drama behind the competition to discover the code of life. Even though her high school counselor told her girls didn’t become scientists, she decided she would. Driven by a passion to understand how nature works and to turn discoveries into inventions, she would help to make what the book’s author, James Watson, told her was the most important biological advance since his codiscovery of the structure of DNA. She and her collaborators turned a curiosity of nature into an invention that will transform the human race: an easy-to-use tool that can edit DNA. Known as CRISPR, it opened a brave new world of medical miracles and moral questions. The development of CRISPR and the race to create vaccines for coronavirus will hasten our transition to the next great innovation revolution. The past half-century has been a digital age, based on the microchip, computer, and internet. Now we are entering a life-science revolution. Children who study digital coding will be joined by those who study genetic code. Should we use our new evolution-hacking powers to make us less susceptible to viruses? What a wonderful boon that would be! And what about preventing depression? Hmmm…Should we allow parents, if they can afford it, to enhance the height or muscles or IQ of their kids? After helping to discover CRISPR, Doudna became a leader in wrestling with these moral issues and, with her collaborator Emmanuelle Charpentier, won the Nobel Prize in 2020. Her story is an “enthralling detective story” (Oprah Daily) that involves the most profound wonders of nature, from the origins of life to the future of our species.

The Search For Human Chromosomes

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Author : Wilson John Wall
language : en
Publisher: Springer
Release Date : 2015-12-11

The Search For Human Chromosomes written by Wilson John Wall and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-12-11 with Science categories.

​This book is a broadly historical account of a remarkable and very exciting scientific story–the search for the number of human chromosomes. It covers the processes and people, culminating in the realization that discovering the number of human chromosomes brought as much benefit as unraveling the genetic code itself. With the exception of red blood cells, which have no nucleus and therefore no DNA, and sex cells, humans have 46 chromosomes in every single cell. Not only do chromosomes carry all of the genes that code our inheritance, they also carry them in a specific order. It is essential that the number and structure of chromosomes remains intact, in order to pass on the correct amount of DNA to succeeding generations and for the cells to survive. Knowing the number of human chromosomes has provided a vital diagnostic tool in the prenatal diagnosis of genetic disorders, and the search for this number and developing an understanding of what it means are the focus of this book.

In Pursuit Of The Gene

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Author : James Schwartz
language : en
Publisher: Harvard University Press
Release Date : 2010-03-30

In Pursuit Of The Gene written by James Schwartz and has been published by Harvard University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-03-30 with Science categories.

The mystery of inheritance has captivated thinkers since antiquity, and the unlocking of this mystery—the development of classical genetics—is one of humanity’s greatest achievements. This great scientific and human drama is the story told fully and for the first time in this book. Acclaimed science writer James Schwartz presents the history of genetics through the eyes of a dozen or so central players, beginning with Charles Darwin and ending with Nobel laureate Hermann J. Muller. In tracing the emerging idea of the gene, Schwartz deconstructs many often-told stories that were meant to reflect glory on the participants and finds that the “official” version of discovery often hides a far more complex and illuminating narrative. The discovery of the structure of DNA and the more recent advances in genome science represent the culmination of one hundred years of concentrated inquiry into the nature of the gene. Schwartz’s multifaceted training as a mathematician, geneticist, and writer enables him to provide a remarkably lucid account of the development of the central ideas about heredity, and at the same time bring to life the brilliant and often eccentric individuals who shaped these ideas. In the spirit of the late Stephen Jay Gould, this book offers a thoroughly engaging story about one of the oldest and most controversial fields of scientific inquiry. It offers readers the background they need to understand the latest findings in genetics and those still to come in the search for the genetic basis of complex diseases and traits.

Genome

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Author : Matt Ridley
language : en
Publisher: Harper Collins
Release Date : 2013-03-26

Genome written by Matt Ridley and has been published by Harper Collins this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-26 with Science categories.

“Ridley leaps from chromosome to chromosome in a handy summation of our ever increasing understanding of the roles that genes play in disease, behavior, sexual differences, and even intelligence. . . . . He addresses not only the ethical quandaries faced by contemporary scientists but the reductionist danger in equating inheritability with inevitability.” — The New Yorker The genome's been mapped. But what does it mean? Matt Ridley’s Genome is the book that explains it all: what it is, how it works, and what it portends for the future Arguably the most significant scientific discovery of the new century, the mapping of the twenty-three pairs of chromosomes that make up the human genome raises almost as many questions as it answers. Questions that will profoundly impact the way we think about disease, about longevity, and about free will. Questions that will affect the rest of your life. Genome offers extraordinary insight into the ramifications of this incredible breakthrough. By picking one newly discovered gene from each pair of chromosomes and telling its story, Matt Ridley recounts the history of our species and its ancestors from the dawn of life to the brink of future medicine. From Huntington's disease to cancer, from the applications of gene therapy to the horrors of eugenics, Ridley probes the scientific, philosophical, and moral issues arising as a result of the mapping of the genome. It will help you understand what this scientific milestone means for you, for your children, and for humankind.

The Missing Gene

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Author : Jay Joseph
language : en
Publisher: Algora Publishing
Release Date : 2006

The Missing Gene written by Jay Joseph and has been published by Algora Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with Medical categories.

What causes psychiatric disorders to appear? Are they primarily the result of people's environments, or of their genes? Increasingly, we are told that research has confirmed the importance of genetic influences on schizophrenia, depression, bipolar disord.

The Gene

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Author : Siddhartha Mukherjee
language : en
Publisher: Random House
Release Date : 2016-06-02

The Gene written by Siddhartha Mukherjee and has been published by Random House this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-06-02 with Science categories.

** NEW YORK TIMES NUMBER ONE BESTSELLER ** The Gene is the story of one of the most powerful and dangerous ideas in our history from the author of The Emperor of All Maladies. The story begins in an Augustinian abbey in 1856, and takes the reader from Darwin’s groundbreaking theory of evolution, to the horrors of Nazi eugenics, to present day and beyond - as we learn to “read” and “write” the human genome that unleashes the potential to change the fates and identities of our children. Majestic in its scope and ambition, The Gene provides us with a definitive account of the epic history of the quest to decipher the master-code that makes and defines humans – and paints a fascinating vision of both humanity’s past and future. For fans of Sapiens by Yuval Noah Harari, A Brief History of Time by Stephen Hawking and Being Mortal by Atul Gwande. ‘Siddhartha Mukherjee is the perfect person to guide us through the past, present, and future of genome science’ Bill Gates ‘A thrilling and comprehensive account of what seems certain to be the most radical, controversial and, to borrow from the subtitle, intimate science of our time...Read this book and steel yourself for what comes next’ Sunday Times