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The Biostatistics Of Aging


The Biostatistics Of Aging
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The Biostatistics Of Aging


The Biostatistics Of Aging
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Author : Gilberto Levy
language : en
Publisher: John Wiley & Sons
Release Date : 2014-02-11

The Biostatistics Of Aging written by Gilberto Levy and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-02-11 with Mathematics categories.


A practical and clarifying approach to aging and aging-related diseases Providing a thorough and extensive theoretical framework, The Biostatistics of Aging: From Gompertzian Mortality to an Index of Aging-Relatedness addresses the surprisingly subtlenotion—with consequential biomedical and public health relevance—of what it means for acondition to be related to aging. In this pursuit, the book presents a new quantitative methodto examine the relative contributions of genetic and environmental factors to mortality anddisease incidence in a population. With input from evolutionary biology, population genetics, demography, and epidemiology, this medically motivated book describes an index of aging-relatedness and also features: Original results on the asymptotic behavior of the minimum of time-to-event random variables, which extends those of the classical statistical theory of extreme values A comprehensive and satisfactory explanation based on biological principles of the Gompertz pattern of mortality in human populations The development of an evolution-based model of causation relevant to mortality and aging-related diseases of complex etiology An explanation of how and why the description of human mortality by the Gompertz distribution can be improved upon from first principles The amply illustrated analysis of real-world data, including a program for conducting the analysis written in the freely available R statistical software Technical appendices including mathematical material as well as an extensive and multidisciplinary bibliography on aging and aging-related diseases The Biostatistics of Aging: From Gompertzian Mortality to an Index of Aging-Relatedness is an excellent resource for practitioners and researchers with an interest in aging and aging-related diseases from the fields of medicine, biology, gerontology, biostatistics, epidemiology, demography, and public health.



The Biostatistics Of Aging


The Biostatistics Of Aging
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Author : Bruce Levin
language : en
Publisher:
Release Date : 2014

The Biostatistics Of Aging written by Bruce Levin and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014 with Mathematics categories.


A practical and clarifying approach to aging and aging-related diseases Providing a thorough and extensive theoretical framework, The Biostatistics of Aging: From Gompertzian Mortality to an Index of Aging-Relatedness addresses the surprisingly subtlenotion--with consequential biomedical and public health relevance--of what it means for acondition to be related to aging. In this pursuit, the book presents a new quantitative methodto examine the relative contributions of genetic and environmental factors to mortality anddisease incidence in a population. With input from evolutionary biology, population genetics, demography, and epidemiology, this medically motivated book describes an index of aging-relatedness and also features: Original results on the asymptotic behavior of the minimum of time-to-event random variables, which extends those of the classical statistical theory of extreme values A comprehensive and satisfactory explanation based on biological principles of the Gompertz pattern of mortality in human populations The development of an evolution-based model of causation relevant to mortality and aging-related diseases of complex etiology An explanation of how and why the description of human mortality by the Gompertz distribution can be improved upon from first principles The amply illustrated analysis of real-world data, including a program for conducting the analysis written in the freely available R statistical software Technical appendices including mathematical material as well as an extensive and multidisciplinary bibliography on aging and aging-related diseases The Biostatistics of Aging: From Gompertzian Mortality to an Index of Aging-Relatedness is an excellent resource for practitioners and researchers with an interest in aging and aging-related diseases from the fields of medicine, biology, gerontology, biostatistics, epidemiology, demography, and public health.



Demography Of Population Health Aging And Health Expenditures


Demography Of Population Health Aging And Health Expenditures
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Author : Christos H. Skiadas
language : en
Publisher: Springer Nature
Release Date : 2020-08-24

Demography Of Population Health Aging And Health Expenditures written by Christos H. Skiadas and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-24 with Social Science categories.


This book provides theoretical and applied material for estimating vital parts of demography and health issues including the healthy aging process along with calculating the healthy life years lost to disability. It further includes the appropriate methodology for the optimum health expenditure allocation. Through providing data analysis, statistical and stochastic methodology, probability approach and important applications, the book explores topics such as aging and mortality, birth-death processes, self-perceived age, life-time and survival as well as pension and labor-force. By providing a methodological approach to health problems in demography and society including and quantifying important parameters, this book is a valuable guide for researchers, theoreticians and practitioners from various disciplines.



The Demography And Epidemiology Of Human Health And Aging


The Demography And Epidemiology Of Human Health And Aging
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Author : Jacob S. Siegel
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-09-30

The Demography And Epidemiology Of Human Health And Aging written by Jacob S. Siegel and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-09-30 with Social Science categories.


With this book, Siegel, an internationally known demographer and gerontologist, has made a unique contribution to the fledgling fields of health demography, and the demography and epidemiology of aging. The book represents a felicitous union of epidemiology, gerontology, and demography, and appears to be the first and only comprehensive text on this subject now available. Drawing on a wide range of sciences in addition to demography, gerontology, and epidemiology, including medical sociology, biostatistics, public policy, bioethics, and molecular biology, the author treats theoretical and applied issues, links methods and findings, covers the material internationally, nationally, and locally, and while focusing on the elderly, treats the entire life course. The methods, materials, and pespectives of demography and epidemiology are brought to bear on such topics as the prospects for future increases in human longevity, the relative contribution of life style, environment, genetics, and chance in human longevity, the measurement of the share of healthy years in total life expectancy, the role of population growth in the rising costs of health care, and the applications of health demography in serving the health needs of local communities. The separate chapters systematically develop the topics of the sources and quality of health data; mortality, life tables, and the measurement of health status; the interrelationships of health, on the one hand, and mortality, fertility, migration, and age structure, on the other; health conditions in the less developed countries; the concepts and theories of aging and projections of the aged population; and local health applications, public health policy, and bioethical issues in health demography. Given its comprehensiveness, clarity, interdisciplinary scope, and authencity, this book appeals to a wide range of users, from students and teachers of medical sociology, the demography of aging, and public health studies to practitioners in these areas, both as a text in health demography and the demography/epidemiology of aging, and as a reference work in these fields.



Longitudinal Data Analysis


Longitudinal Data Analysis
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Author : Jason Newsom
language : en
Publisher: Routledge
Release Date : 2013-06-19

Longitudinal Data Analysis written by Jason Newsom and has been published by Routledge this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-19 with Psychology categories.


This book provides accessible treatment to state-of-the-art approaches to analyzing longitudinal studies. Comprehensive coverage of the most popular analysis tools allows readers to pick and choose the techniques that best fit their research. The analyses are illustrated with examples from major longitudinal data sets including practical information about their content and design. Illustrations from popular software packages offer tips on how to interpret the results. Each chapter features suggested readings for additional study and a list of articles that further illustrate how to implement the analysis and report the results. Syntax examples for several software packages for each of the chapter examples are provided at www.psypress.com/longitudinal-data-analysis. Although many of the examples address health or social science questions related to aging, readers from other disciplines will find the analyses relevant to their work. In addition to demonstrating statistical analysis of longitudinal data, the book shows how to interpret and analyze the results within the context of the research design. The methods covered in this book are applicable to a range of applied problems including short- to long-term longitudinal studies using a range of sample sizes. The book provides non-technical, practical introductions to the concepts and issues relevant to longitudinal analysis. Topics include use of publicly available data sets, weighting and adjusting for complex sampling designs with longitudinal studies, missing data and attrition, measurement issues related to longitudinal research, the use of ANOVA and regression for average change over time, mediation analysis, growth curve models, basic and advanced structural equation models, and survival analysis. An ideal supplement for graduate level courses on data analysis and/or longitudinal modeling taught in psychology, gerontology, public health, human development, family studies, medicine, sociology, social work, and other behavioral, social, and health sciences, this multidisciplinary book will also appeal to researchers in these fields.



Forecasting The Health Of Elderly Populations


Forecasting The Health Of Elderly Populations
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Author : Kenneth G. Manton
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Forecasting The Health Of Elderly Populations written by Kenneth G. Manton and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Mathematics categories.


Models to forecast changes in mortality, morbidity, and disability in elderly populations are essential to national and state policies for health and welfare programs. This volume presents a wide-ranging survey of the forecasting of health of elderly populations, including the modelling of the incidence of chronic diseases in the elderly, the differing perspectives of actuarial and health care statistics, and an assessment of the impact of new technologies on the elderly population. Amongst the topics covered are - uncertainties in projections from census and social security data and actuarial approaches to forecasting - plausible ranges for population growth using biol ogical models and epidemiological time series data - the financing of long term care programs - the effects of major disabling diseases on health expenditures - forecasting cancer risks and risk factors As a result, this wide-ranging volume will become an indispensable reference for all those whose research touches on these topics.



Biostatistics And Epidemiology


Biostatistics And Epidemiology
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Author : Sylvia Wassertheil-Smoller
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-05-10

Biostatistics And Epidemiology written by Sylvia Wassertheil-Smoller and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-05-10 with Medical categories.


For the new edition of Biostatistics and Epidemiology, Dr. Wassertheil-Smoller has included several new chapters (genetic statistics, molecular epidemiology, scientific integrity and research ethics) and a new appendix on the basic concepts of genetics and a glossary of genetic terminology. She has also expanded the coverage of multi-center trials (an important aspect of implementation of the standards of evidence-based medicine), controversies in screening for prostate, colon, breast, and other cancers.



Statistical Methods In Ageing Epidemiology


Statistical Methods In Ageing Epidemiology
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Author : Fiona E Matthews
language : en
Publisher: CRC Press
Release Date : 2019-06-30

Statistical Methods In Ageing Epidemiology written by Fiona E Matthews and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-06-30 with categories.


Ageing epidemiology is the study of the health of an ageing population. It is a very active area of research in epidemiology, but has its own issues, which has led to the development of methodology specific to the area. This book covers all the essential statistical tools for analysing cross sectional and longitudinal epidemiological data for ageing research. It has lots of worked examples using real data to illustrate the methods, and Stata and R code for all the examples.



Computational Systems Biology


Computational Systems Biology
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Author : Andres Kriete
language : en
Publisher: Elsevier Inc. Chapters
Release Date : 2013-11-26

Computational Systems Biology written by Andres Kriete and has been published by Elsevier Inc. Chapters this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-26 with Medical categories.


What makes the study of aging particularly challenging is the wide spectrum of phenotypical changes that can be observed during its progression. While initial attention was paid to damage accumulation, dysfunction, and failure, it is now realized that aging, and associated diseases including dementias, are influenced by a multitude of interacting factors. Proximal mechanisms beyond passive accumulation of damage include regulatory mechanisms, stress responses, changes in networks, as well as genetic and stochastic effects. The application of computational systems biology in aging, which is in line with other attempts to overcome the study of isolated or compartmentalized mechanisms, has made initial progress allowing us to simulate partial aspects of the aging dynamics and to make new hypotheses about how these aging mechanism shape disease progression. Here we provide examples for analysis of networks, regulatory mechanisms, and spatiotemporal effects in the study of proximal mechanisms of aging and Parkinson’s Disease. In addition, we introduce complexity theories that may contribute to explain the ultimate causes of aging with an evolutionary view.



Biostatistics For Population Health


Biostatistics For Population Health
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Author : Lisa M. Sullivan
language : en
Publisher: Jones & Bartlett Learning
Release Date : 2020-04-02

Biostatistics For Population Health written by Lisa M. Sullivan and has been published by Jones & Bartlett Learning this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-04-02 with Education categories.


Written for undergraduate and graduate students with little or no mathematical background, Biostatistics for Population Health: A Primer offers current and future health professionals a clear, and accessible approach to learning the basic tools and techniques necessary to conduct biostatistical analyses and the professional confidence to critically evaluate and interpret biostatistical findings. Each unit begins with a contemporary population health issue (e.g., the opioid crisis, physical inactivity among children, diabetes) and raises questions that require the use of techniques discussed in that unit. Each technique, in turn, is illustrated with realistic, contemporary examples (e.g. vaping) to pique student interest. By the end of the unit, students are encouraged to apply the techniques to address the questions that were raised.