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The Decade Of Autoimmunity


The Decade Of Autoimmunity
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The Decade Of Autoimmunity


The Decade Of Autoimmunity
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Author : Yehuda Shoenfeld
language : en
Publisher: Elsevier
Release Date : 1999-02-15

The Decade Of Autoimmunity written by Yehuda Shoenfeld and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999-02-15 with Medical categories.


This book is a direct result of 10 years of the well-known "Autoimmunity Days" in Israel, which are increasingly becoming an international focal point for autoimmunity scientists. Top researchers provide coverage of the most important knowledge generated during the last decade. The volume can therefore be seen almost as a textbook on autoimmunity, projecting from the last decade to the next millennium. A variety of different subjects in autoimmunity, from etiology to pathogenesis, from postulated mechanisms to innovative therapeutic modalities, is handled by noted contributors, while additional authors contribute top papers which significantly enhance a better understanding of autoimmunity. An excellent treatise on the subject, and a worthwhile addition to both clinical and research libraries.



Endocrine And Organ Specific Autoimmunity


Endocrine And Organ Specific Autoimmunity
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Author : George S. Eisenbarth
language : en
Publisher:
Release Date : 1999

Endocrine And Organ Specific Autoimmunity written by George S. Eisenbarth and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with categories.


Organ specific autoimmune disorders as a group are responsible for a major portion of all debilitating and at times life threatening chronic diseases. Over the past decade more has been learned concerning the molecular pathogenesis of these disorders than during the past 100 years.



The Value Of Bcg And Tnf In Autoimmunity


The Value Of Bcg And Tnf In Autoimmunity
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Author : Denise Faustman
language : en
Publisher: Academic Press
Release Date : 2014-03-13

The Value Of Bcg And Tnf In Autoimmunity written by Denise Faustman and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-03-13 with Medical categories.


The Value of BCG and TNF in Autoimmunity provides an overview of current research and thinking related to tumor necrosis factor (TNF) induction and the use of the bacillus Calmette-Guérin (BCG) vaccine as potential treatment approaches to diverse forms of autoimmunity. BCG, commonly known as an anti-tuberculosis vaccine, is being explored in worldwide clinical trials as an approach to the treatment of certain forms of autoimmunity. The scope of research behind this therapeutic approach spans from the basic science of TNF signaling to research in diverse autoimmune disciplines, such as type 1 diabetes and multiple sclerosis. Overall, the book focuses on the lessons that can be learned from the researchers' individual experiences and data, and provides a rationale for bringing the inexpensive, generic BCG vaccine to the forefront of clinical trials in different forms of autoimmunity. Editor awarded 2005: Oprah Achievement Award," Top Health Breakthrough by a Female Scientist" Brings into one resource the international scientific literature on a unique way to treat autoimmunity Provides a different perspective on treatment approaches for certain autoimmune conditions Discusses TNF induction, rather than anti-TNF, as a therapeutic pathway for autoimmunity treatment



Precision Medicine And Artificial Intelligence


Precision Medicine And Artificial Intelligence
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Author : Michael Mahler
language : en
Publisher: Academic Press
Release Date : 2021-03-12

Precision Medicine And Artificial Intelligence written by Michael Mahler and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-12 with Science categories.


Precision Medicine and Artificial Intelligence: The Perfect Fit for Autoimmunity covers background on artificial intelligence (AI), its link to precision medicine (PM), and examples of AI in healthcare, especially autoimmunity. The book highlights future perspectives and potential directions as AI has gained significant attention during the past decade. Autoimmune diseases are complex and heterogeneous conditions, but exciting new developments and implementation tactics surrounding automated systems have enabled the generation of large datasets, making autoimmunity an ideal target for AI and precision medicine. More and more diagnostic products utilize AI, which is also starting to be supported by regulatory agencies such as the Food and Drug Administration (FDA). Knowledge generation by leveraging large datasets including demographic, environmental, clinical and biomarker data has the potential to not only impact the diagnosis of patients, but also disease prediction, prognosis and treatment options. Allows the readers to gain an overview on precision medicine for autoimmune diseases leveraging AI solutions Provides background, milestone and examples of precision medicine Outlines the paradigm shift towards precision medicine driven by value-based systems Discusses future applications of precision medicine research using AI Other aspects covered in the book include regulatory insights, data analytics and visualization, types of biomarkers as well as the role of the patient in precision medicine



Atherosclerosis And Autoimmunity


Atherosclerosis And Autoimmunity
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Author : Yehuda Shoenfeld
language : en
Publisher: Elsevier
Release Date : 2001-02-27

Atherosclerosis And Autoimmunity written by Yehuda Shoenfeld and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-02-27 with Medical categories.


Presenting further studies in the prevention and treatment of coronary artery disease, this book brings together the knowledge accrued in the past decade concerning the role of immunity in the initiation and perpetuation of atherosclerosis. A strong group of international contributors summarize the diverse aspects of the interrelationship between the immune system and atherosclerosis.



Translational Autoimmunity Volume 3


Translational Autoimmunity Volume 3
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Author : Nima Rezaei
language : en
Publisher: Elsevier
Release Date : 2022-04-05

Translational Autoimmunity Volume 3 written by Nima Rezaei and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-04-05 with Medical categories.


Translational Autoimmunity: Autoimmune Diseases in Different Clinical Settings addresses autoimmunity and associated conditions, such as aging, infectious diseases, cancer, neurodegeneration, psychological disorders, fertility, inflammatory vascular diseases, and interstitial lung diseases. The book addresses sufficiently basic questions on how the immune system is designed to distinguish self from no self and behave such that it's able to maintain self-tolerance, how does it work in infections, and how it elicits an auto-reactive state and develops self-antigens seen in autoimmune conditions. This is followed by an overview on the genetic and clinical aspects of the spectrum of autoimmune diseases which are broadly categorized into two types of organ specific autoimmune diseases and non-organ specific autoimmune diseases (also known as systemic autoimmune diseases). Covers clinical aspects of autoimmunity and translational immunology studies in autoimmunity in different clinical settings Meets the needs of basic scientists, clinicians, translational scientists and industry partners Supported by a systematic appraisal of the most recent evidence



Cancer And Autoimmunity


Cancer And Autoimmunity
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Author : M.E. Gershwin
language : en
Publisher: Elsevier
Release Date : 2000-03-27

Cancer And Autoimmunity written by M.E. Gershwin and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-03-27 with Medical categories.


Of the two disciplines in parallel development for two decades, tumor immunology and transplantation immunology, the latter has thrived and has led to some of the most critical discoveries in immunobiology. The former continues to thwart both scientists and clinicians alike. The goal of immunologists in modern day research is to develop a simple and effective means to manipulate cancer in vivo, possibly encompassing several venues: identifying a phenotypic marker and the use of either active or passive immunization; include the use of passive reagents carrying "warheads" to selectively destroy cancer cells; or altering the basic process of cell survival. This excellent multidiscipline-authored volume presents a theme which has not been well described before. The papers include both basic and clinical science and range from sophisticated molecular biology to little more than phenomenology (e.g. the increased association of cancer in some autoimmune diseases and increased presentation of autoimmune phenomena in malignant condition). This, however, is state-of-the-art. This collection of themes will be of use not only to bench scientists, but also to clinicians who treat patients. The book represents progress at the cutting edge of this discipline, and points the way to further developments in the "black box" of immunology.



Translational Autoimmunity Volume 1


Translational Autoimmunity Volume 1
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Author : Nima Rezaei
language : en
Publisher: Elsevier
Release Date : 2021-10-25

Translational Autoimmunity Volume 1 written by Nima Rezaei and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-10-25 with Medical categories.


Translational Autoimmunity: Etiology of Autoimmune Diseases is the first volume of the Translational Immunology book series. To attain its purpose as a detailed translational step to tackle autoimmunity, this volume sufficiently addresses basic questions on how the immune system is designed to distinguish self from nonself. It discusses the known mechanisms that lead to the maintenance of self-tolerance, presents potential triggers and malfunctions that impede normal immune processes, and demonstrates how the immune system induces an autoreactive state that results in the recognition of self-antigens seen in autoimmune conditions. Includes coverage of basic immunology, the clinical aspects of autoimmunity, and translational immunology studies in autoimmunity Presents key concepts supported by a systematic appraisal of the most recent evidence Assists students at all the academic levels while also being applicable to scientists who work with autoimmunity Designed for learning, teaching, review, testing, practice and research



Vaccines Autoimmunity And The Changing Nature Of Childhood Illness


Vaccines Autoimmunity And The Changing Nature Of Childhood Illness
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Author : Thomas Cowan
language : en
Publisher: Chelsea Green Publishing
Release Date : 2018-08-14

Vaccines Autoimmunity And The Changing Nature Of Childhood Illness written by Thomas Cowan and has been published by Chelsea Green Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-08-14 with Health & Fitness categories.


One Doctor’s Surprising Answer to the Epidemic of Autoimmunity and Chronic Disease Over the past fifty years, rates of autoimmunity and chronic disease have exploded: currently 1 in 2.5 American children has an allergy, 1 in 11 has asthma, 1 in 13 has severe food allergies, and 1 in 36 has autism. While some attribute this rise to increased awareness and diagnosis, Thomas Cowan, MD, argues for a direct causal relationship to a corresponding increase in the number of vaccines American children typically receive—approximately 70 vaccine doses by age eighteen. The goal of these vaccines is precisely what we’re now seeing in such abundance among our chronically ill children: the provocation of immune response. Dr. Cowan looks at emerging evidence that certain childhood illnesses are actually protective of disease later in life; examines the role of fever, the gut, and cellular fluid in immune health; argues that vaccination is an ineffective (and harmful) attempt to shortcut a complex immune response; and asserts that the medical establishment has engaged in an authoritarian argument that robs parents of informed consent. His ultimate question, from the point of view of a doctor who has decades of experience treating countless children is: What are we really doing to children when we vaccinate them?



Enhancing Nih Research On Autoimmune Disease


Enhancing Nih Research On Autoimmune Disease
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Author : National Academies Of Sciences Engineeri
language : en
Publisher: National Academies Press
Release Date : 2023-02-10

Enhancing Nih Research On Autoimmune Disease written by National Academies Of Sciences Engineeri and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-02-10 with Medical categories.


Autoimmune diseases occur when the body's immune system malfunctions and mistakenly attacks healthy cells, tissues, and organs. Strong data on the incidence and prevalence of autoimmune diseases are limited, but a 2009 study estimated the prevalence of autoimmune diseases in the U.S. to be 7.6 to 9.4 percent, or 25 to 31 million people today. This estimate, however, includes only 29 autoimmune diseases, and it does not account for increases in prevalence in the last decade. By some counts, there are around 150 autoimmune diseases, which are lifelong chronic illnesses with no known cures. The National Academies of Sciences, Engineering, and Medicine was asked to assess the autoimmune disease research portfolio of the National Institutes of Health (NIH). Enhancing NIH Research on Autoimmune Disease finds that while NIH has made impressive contributions to research on autoimmune diseases, there is an absence of a strategic NIH-wide autoimmune disease research plan and a need for greater coordination across the institutes and centers to optimize opportunities for collaboration. To meet these challenges, this report calls for the creation of an Office of Autoimmune Disease/Autoimmunity Research in the Office of the Director of NIH. The Office could facilitate NIH-wide collaboration, and engage in prioritizing, budgeting, and evaluating research. Enhancing NIH Research on Autoimmune Disease also calls for the establishment of long term systems to collect epidemiologic and surveillance data and long term studies (20+ years) to study disease across the life course. Finally, the report provides an agenda that highlights research needs that crosscut many autoimmune diseases, such as understanding the effect of environmental factors in initiating disease.