The Effects Of Antihormones On The Development Of The Zebra Finch Song System
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The Effects Of Antihormones On The Development Of The Zebra Finch Song System
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Author : Greta Anne Mathews
language : en
Publisher:
Release Date : 1989
The Effects Of Antihormones On The Development Of The Zebra Finch Song System written by Greta Anne Mathews and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1989 with Birdsongs categories.
The Effects Of Endocrine Disrupting Chemicals On The Development Of The Zebra Finch Song System
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Author : Kristofor Carleton Schuett
language : en
Publisher:
Release Date : 1999
The Effects Of Endocrine Disrupting Chemicals On The Development Of The Zebra Finch Song System written by Kristofor Carleton Schuett and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with categories.
The Role Of Ribosomal Protein L7 An Estrogen Receptor Coactivator On The Development Of Zebra Finch Taeniopygia Guttata Song System
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Author : Kelli Adams Duncan
language : en
Publisher:
Release Date : 2008
The Role Of Ribosomal Protein L7 An Estrogen Receptor Coactivator On The Development Of Zebra Finch Taeniopygia Guttata Song System written by Kelli Adams Duncan and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with Finches categories.
The Australian zebra finch (Taeniopygia guttata) serves as an excellent model organism for studying the mechanisms that influence brain sexual differentiation. The brain and behavior of the zebra finch are sexually dimorphic. The regions of the brain that control the learning and production of song (song control nuclei) are significantly larger in the male brain than in the female brain and only males sing courtship songs, thus the majority of past research has focused on the development of these sex differences. In the majority of mammals, brain sexual differentiation occurs because hormones secreted from the gonads act to initiate male or female brain development. In zebra finches, estradiol is sufficient to masculinize the male brain, however manipulations of developmental hormone exposure fail to fully reverse the sex differences in song nuclei size. Furthermore, genetic females induced to develop functional testicular tissue do not develop a completely masculinized song system and castration has no effect on development of the song system in males. The source of the increased estrogenic signal in male zebra finch brain has yet to be identified, but data suggest that other neuronal factors play a role in development of the song control nuclei. Coregulators, such as coactivators and corepressors, are proteins and RNA activators that work by enhancing or depressing transcriptional activity of the nuclear steroid receptor with which they associate. Coregulators also modulate the development of sex-specific brain morphology and behavior in rodents and birds and may help to explain the difficulties observed in altering song nuclei development via castration and gonadal hormone replacement. As an estrogen receptor-[alpha] coactivator, ribosomal protein L7 (RPL7) is able to make the brain more sensitive to estradiol by enhancing the effects of steroid receptor action. Therefore, this dissertation addressed the following questions regarding RPL7: (1) is RPL7 expression sexually dimorphic in the song nuclei of the zebra finch brain?; (2) is RPL7 protein expression regulated by steroid hormones?; and (3) does decreasing RPL7 protein expression with antisense oligonucleotides alter neuronal survival in vivo and song nuclei size and neuron number in vitro? Collectively, these studies will provide valuable information about the role of steroid receptor coactivators in development of the zebra finch song system and on the role of coactivators on sexual differentiation of the brain.
The Effect Of Dicofol On The Song Control Area Of The Zebra Finch
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Author : Renee Victoria Hoyos
language : en
Publisher:
Release Date : 1998
The Effect Of Dicofol On The Song Control Area Of The Zebra Finch written by Renee Victoria Hoyos and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998 with categories.
Effects Of Psychological Stressors And Delta 9 Thc Acutely And Chronically On Zebra Finch Song Behavior And Dendritic Spine Density
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Author : Tessa Holland
language : en
Publisher:
Release Date : 2020
Effects Of Psychological Stressors And Delta 9 Thc Acutely And Chronically On Zebra Finch Song Behavior And Dendritic Spine Density written by Tessa Holland and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020 with categories.
This dissertation investigated song performance and dendritic spine density, following acute restraint stress in adult zebra finches and, following chronic mild stress and CB1 receptor partial agonist [delta]9-tetrahydrocannabinol ( [delta]9-THC) treatments (3 mg/kg) during sensorimotor development or adulthood. CB1 receptor agonists and stressors have mechanistic overlap: a stressor activates glucocorticoid corticosterone release in the hypothalamic-pituitary-adrenal axis, and endocannabinoids anandamide (AEA) and 2-arachidonoylglycerol (2-AG) are CB1 receptor agonists which operate as an endogenous stress buffer system that turns off the response. The endocannabinoid system is prominent during late postnatal development and may modulate important synaptic fine-tuning. Chronic CB1 receptor agonist treatment or stressors during this developmental stage may disrupt appropriate endocannabinoid signaling mediating brain development. Male zebra finches possess a developmental, sensorimotor critical period for learning a song in a mechanism similar to language acquisition in humans. Initially in sensorimotor development, zebra finches possess a surplus of dendritic spines, which are the anatomical basis of the post-synaptic site with excitatory input and may represent morphological building blocks of learning and memory. Over time, a net elimination occurs as part of the developmental learning process. In this dissertation, acute restraint stress (30 minutes) in adults rapidly increased plasma corticosterone levels, altered performance of spectral and temporal acoustic features, and stimulated dendritic spine and c-Fos immunolabeled nuclei density in higher-order acoustic region NCM. [delta]9-THC, the principal psychoactive component of marijuana, inhibits perceptual sensory processing, and [delta]9-THC pretreatment antagonized the effects of stress on c-Fos density in NCM in a CB1 receptor inverse agonist/antagonist SR141716 (6 mg/kg)-reversible manner. The acute effects differed from chronic effects. In adult groups, chronic mild stress or [delta]9-THC treatments alone did not alter corticosterone levels, song acoustic features, or dendritic spine density in NCM or basal ganglia/striatal region Area X. Both chronic stress and [delta]9-THC treatments during sensorimotor song development resulted in effects persistent into adulthood, with reduced syllable entropy and dendritic spine density in Area X. These effects suggest an interference with typical developmental song learning and brain development. Adolescent brain development may be vulnerable to long-term consequences following chronic exposure to CB1 receptor agonists or stressors, and their effects likely differ than exposure during adulthood. This distinction is important to the elucidation of mechanisms and outcomes of marijuana and psychological disorders, such as depression.
Development Of Brain And Behavior In Birds
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Author : Juli Wade
language : en
Publisher: Morgan & Claypool Publishers
Release Date : 2012-03
Development Of Brain And Behavior In Birds written by Juli Wade and has been published by Morgan & Claypool Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-03 with Birds categories.
Sex differences in brain and behavior are widespread across vertebrates. Birds exhibit remarkable examples of these types of parallels between structure and function. For example, only male zebra finches sing, and the brain areas and muscles controlling the learning and production of these vocalizations are greatly enhanced in males compared to females. These sex differences are permanently established in development. Some songbirds, unlike zebra finches, change their songs seasonally. In a number of these species, the brain regions exhibit changes in neuron loss and incorporation across these periods. The mechanisms involved in these types of sexual differentiation and adult plasticity are describedOCothey likely involve both steroid hormones and genetic (protein) factors. The strength of the relationships between morphology and behavior, as well as many other factors, has made birds outstanding models for the investigation of numerous functions. These include the mechanisms regulating vocal learning, auditory perception, neurogenesis, and cell survival. The lessons learned have broad implications for health-related processes and basic biological principles.Table of Contents: Introduction / Song and Song Learning / Other Social/Reproductive Behaviors / Conclusions and Ideas for Future Directions"
The Zebra Finch Taeniopygia Guttata Brain Has The Capacity To Synthesize Neurosteroids That May Impact Song System Organization And Function
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Author : Sarah Edythe London
language : en
Publisher:
Release Date : 2005
The Zebra Finch Taeniopygia Guttata Brain Has The Capacity To Synthesize Neurosteroids That May Impact Song System Organization And Function written by Sarah Edythe London and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with categories.
Neuroplasticity Development And Steroid Hormone Action
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Author : Robert J. Handa
language : en
Publisher: CRC Press
Release Date : 2001-07-30
Neuroplasticity Development And Steroid Hormone Action written by Robert J. Handa and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-07-30 with Medical categories.
A compilation of cutting-edge research, Neuroplasticity, Development, and Steroid Hormone Action explores the effects of steroid hormones on brain development, function, and aging. The experimental approaches used by the authors ranges from molecular to behavioral and endocrine to neurobiological. It contains scientific photographs, line drawings, tables, color illustrations, and graphs, this interesting and timely text covers the neuroplastic effects of steroid hormones throughout the lifetime of various animal models, such as bees, fish, lizards, turtles, birds, mice, rats, and primates.
Developmental Psychobiology
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Author : Elliott M. Blass
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Developmental Psychobiology written by Elliott M. Blass and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
ELLIOTT M. BLASS Fifteen years have passed since the first volume on developmental psychobiology (Blass, 1986) appeared in this series and 13 since the publication of the second volume (Blass, 1988). These volumes documented the status of the broad domain of scientific inquiry called developmental psychobiology and were also written with an eye to the future. The future has been revolutionary in at least three ways. First, there was the demise of a descriptive ethology as we had known it, to be replaced first by sociobiology and later by its more sophisticated versions based on quantitative predictions of social interactions that reflected relatedness and inclu sive fitness. Second, there was the emergence of cognitive science, including cogni tive development, as an enormously strong and interactive multidisciplinary effort. Making the "functional" brain more accessible made this revolution all the more relevant to our discipline. In the laboratory, immunocytochemical detection of immediate / early genes, such as los, now allows us to trace neuronal circuits activated during complex behaviors. The "functional" brain of primates, especially humans, was also made very accessible through neuroimaging with which we can look at and into brains as they solve and attempt to solve particular tasks. Those of us who were trained in neurology as graduate students two or three decades ago recognize only the people in white coats and patients in beds or on gurneys when we visit neurologi cal units today. The rest is essentially new.
Hormones Brain And Behavior
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Author :
language : en
Publisher: Academic Press
Release Date : 2016-11-09
Hormones Brain And Behavior written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-11-09 with Medical categories.
Hormones, Brain and Behavior, Third Edition offers a state-of-the-art overview of hormonally-mediated behaviors, including an extensive discussion of the effects of hormones on insects, fish, amphibians, birds, rodents, and humans. Entries have been carefully designed to provide a valuable source of information for students and researchers in neuroendocrinology and those working in related areas, such as biology, psychology, psychiatry, and neurology. This third edition has been substantially restructured to include both foundational information and recent developments in the field. Continuing the emphasis on interdisciplinary research and practical applications, the book includes articles aligned in five main subject sections, with new chapters included on genetic and genomic techniques and clinical investigations. This reference provides unique treatment of all major vertebrate and invertebrate model systems with excellent opportunities for relating behavior to molecular genetics. The topics cover an unusual breadth (from molecules to ecophysiology), ranging from basic science to clinical research, making this reference of interest to a broad range of scientists in a variety of fields. Comprehensive and updated coverage of a rapidly growing field of research Unique treatment of all major vertebrate and invertebrate model systems with excellent opportunities for relating behavior to molecular genetics Covers an unusual breadth of topics and subject fields, ranging from molecules to ecophysiology, and from basic science to clinical research Ideal resource for interdisciplinary learning and understanding in the fields of hormones and behavior