The Endocannabinoid System And Cannabis
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Cannabinoids As Therapeutics
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Author : Raphael Mechoulam
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-03-30
Cannabinoids As Therapeutics written by Raphael Mechoulam and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-03-30 with Medical categories.
Only a few years ago the endocannabinoid system was unknown. Today we are aware that endocannabinoids are involved in many of the functions of the mammalian body - in neuroprotection, appetite and suckling, pain, reproduction, anxiety, memory, bone formation etc. This volume presents an up-to-date picture of some of the major fields of endocannabinoid research. It summarizes the actions of the endocannabinoids on various physiological systems and opens new therapeutic windows to a large number of diseases. The first chapter, on the use of Cannabis in India, can be viewed as an expression of thanks to the herbal practitioners, who for centuries passed on the medical traditions associated with the drug. The chapter on chemistry is a short summary of active plant, synthetic and endogenous cannabinoids being investigated today, many of which are mentioned later in the book. Cannabidiol is an unusual cannabinoid - it does not bind to the known receptors and yet exerts a variety of effects. Hence a chapter is devoted to it. Further chapters deal with the endocannabinoid system and the endocannabinoids in a variety of conditions and physiological systems. The concluding chapter describes the research done on Sativex®, a standardized plant extract, shortly to be introduced in Canada as a drug for multiple sclerosis. The intended audience is drug researchers (medicinal chemists, pharmacologists, clinicians), neuroscientists, physiologists, and clinicians interested in the effect of the endocannabinoid system in various physiological systems.
The Endocannabinoid System Filling The Translational Gap Between Neuroscience And Psychiatry
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Author : Marco Colizzi
language : en
Publisher: Frontiers Media SA
Release Date : 2022-01-24
The Endocannabinoid System Filling The Translational Gap Between Neuroscience And Psychiatry written by Marco Colizzi and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-24 with Medical categories.
Healing With Cannabis
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Author : Cheryl Pellerin
language : en
Publisher: Simon and Schuster
Release Date : 2020-08-04
Healing With Cannabis written by Cheryl Pellerin and has been published by Simon and Schuster this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-04 with Medical categories.
Named a 2023 TOP BOOK ON CANNABIS by CBD Oracle 2020 GOLD MEDAL WINNER of the Nonfiction Book Awards (Nonfiction Authors Association) An Informative Read for an Audience Interested in Why and How Medical Cannabis Helps Treat a Range of Illnesses—Maybe All of Them With cannabis approved in fourteen states (including the District and two US territories), medical cannabis approved in at least 35 states, and hemp (very-low-THC cannabis) off the controlled substances list, millions now treat their ills with medical cannabis or non-intoxicating cannabinoids like CBD. But lots of them don’t know why or how cannabis works in the body. Healing with Cannabis informs readers about an ancient biological system newly discovered in every vertebrate on the planet—the endocannabinoid system. This system is the only reason cannabis works in the body, and it’s why cannabis is effective in a broad range of disorders. The book offers an informal tone, a little humor, interviews with some of the most knowledgeable cannabinoid scientists, color images, and a selection of research and clinical trials to recount the story of the endocannabinoid system, its origins in the earliest forms of life on Earth, the evolution of its elements, and the discoveries, millions of years later, of more of its elements over time. Healing with Cannabis explains the surprising reasons evolution conserved the endocannabinoid system over a billion years and tells specifically how cannabis has positive effects on some of society’s most devastating illnesses, including neurodegenerative diseases, post-traumatic stress disorder, pain, movement disorders, cancer and chemotherapy, and addiction. The book also shows how medical cannabis, widely available, will change the face of public health, and how nearly everyone can benefit from this versatile medicine that has a 5,000-year history of safe and effective use.
Cannabis And The Endocannabinoid System
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Author : Arnold Kuntz Ph D
language : en
Publisher:
Release Date : 2020-11-18
Cannabis And The Endocannabinoid System written by Arnold Kuntz Ph D and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-18 with categories.
The endocannabinoid system is a complex biological system in the human body. Medical researchers discovered it in the 1990s, but much is still unknown about how it works and its interactions. Today, experts know that it impacts several major processes, including appetite, sleep, mood, and memory, but there is much more yet to be discovered. The endocannabinoid system has three components: receptors, enzymes, and endocannabinoids. These parts function regardless of whether someone uses CBD or not.Here is an overview of each component: Receptors exist throughout the body and are a substance to which endocannabinoids bind; Enzymes appear in many forms, but only two types of enzymes break down endocannabinoids; and Endocannabinoids complement the body by keeping internal functions running smoothly. Understanding the effects of CBD involves examining the relationship between the receptors and endocannabinoids. There are two types of receptors: CB1 and CB2. CB1 receptors are primarily in the central nervous system and are responsible for governing coordination, movement, pain, appetite, memory, mood, and other functions. The CB2 receptors are in the peripheral nervous system, influencing pain, and inflammation.After the enzymes break down the cannabinoids, the endocannabinoids look to bind with receptors. Researchers believe that CBD does not directly attach itself to the receptor but influences it in some way. Activating these receptors is what allows for many of the health benefits that people associate with the compound. CBD can also influence non-cannabinoid receptors. CBD modulates the 5ht serotonin receptor, which can treat psychotic disorders. It can also affect the TRPV1 receptor, which is responsible for pain and inflammation
Endocannabinoids
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Author : Emmanuel S Onaivi
language : en
Publisher: CRC Press
Release Date : 2005-11-01
Endocannabinoids written by Emmanuel S Onaivi and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-11-01 with Science categories.
Over the past decade, there have been major advances in understanding the mechanisms whereby marijuana interacts with the brain in producing psychoactive and potentially therapeutic effects. The discovery of specific gene coding for cannabinoid receptors activated by smoking marijuana, and the finding of endogenous cannabinoids, which also activate the receptors, have transformed cannabinoid research into mainstream science with significant implications in human health and disease Endocannabinoids: The Brain and Body’s Marijuana and Beyond documentsadvances in the discovery and functioning of naturally occurring marijuana-like substances in human biology. It explores recent findings that point to the existence of an endocannabinoid physiological control system (EPCS) that directly impacts human development, health, and disease. While cannabinoid effects on the brain have received the greatest attention throughout the literature, this work looks at research on the endogenous cannabinoid system’s association across all of human physiology, including the immune, endocrine, and reproductive systems. With thoroughly researched and exceptionally insightful contributions from more than three-dozen top-flight researchers representing a cross-section of disciplines from molecular biology, genetics, and neurology to gynecology, physiology, and pharmacology, this work explores a range of topics as wide as the human body is complex. These topics include the EPCS’s relation to cell development and regulation, CNS function, immune function modulation, reproduction, and digestion, as well as its function in mental illness, neurodegenerative diseases, and cancer. The final section in the book considers the significance of endogenous cannabinoids found in some of the simplest multicellular organisms in the animal kingdom, as well as in mammalian cells at the earliest stages of development, all of which suggests that they play a fundamental role in human biology. Enocannabinoids: The Brain and Body’s Marijuana and Beyond explores areas that few books have ventured into, providing cutting-edge information that will ultimately help us better understand human biology at the systemic and perhaps even cellular level, as well as lead to the development of a whole new range of medications.
Cannabinoids
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Author : Vincenzo Di Marzo
language : en
Publisher: John Wiley & Sons
Release Date : 2014-07-18
Cannabinoids written by Vincenzo Di Marzo and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-07-18 with Science categories.
'Cannabinoids' is a broad term covering a group of natural products from Cannabis sativa, one of which locks on to specific receptors – protein molecules on the surface of cells – known as cannabinoid receptors. Over the past decades scientists have found that cannabinoid receptors and their endogenous ligands, the endocannabinoids, are involved in a vast array of physiological functions, including helping to control brain activity, energy metabolism, heart function, the immune system and even reproduction. In Cannabinoids, Vincenzo Di Marzo has assembled contributions from international experts to provide the definitive guide to what continues to be a rapidly developing research field. After an introductory historical chapter, the book continues by looking at the biochemical, genetic and molecular elements of cannabinoids, followed by chapters covering their role in health and disease. The final chapter outlines the need for a new nomenclature to reflect the complex and multi-disciplinary nature of this area.
Cannabinoids And Pain
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Author : Samer N. Narouze
language : en
Publisher: Springer Nature
Release Date : 2021-07-01
Cannabinoids And Pain written by Samer N. Narouze and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-07-01 with Medical categories.
This book presents a well-balanced view of the potential medical use of cannabinoids in pain. It comprehensively covers the current challenges with medical cannabis utilization and provides recommendations for research and future directions. Organized into nine sections, the book begins with an introduction to medical cannabis, including its history, regulations, and the general attitudes of pain physicians on cannabis. Section two explores the biological effects of marijuana via the endocannabinoid system and its complex structure of receptors and enzymes. Sections three, four, and five then delve further into pharmacology and the mechanisms of action applicable to cannabinoids in managing pain. Timely and socially conscious, section six examines the benefits of substituting opioids with cannabinoids for preoperative management. Echoing the book's well-rounded content, sections seven and eight consider the challenges with medical cannabis, including safety and quality control, brain development risks, vaping hazards, and withdrawal. The book then closes with a look at the future of cannabis in medical research. Thoroughly and equitably composed, Cannabinoids and Pain is an invaluable resource for primary care physicians, pain and palliative care physicians, and oncologists.
The Endocannabinoid System
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Author : Eric Murillo-Rodríguez
language : en
Publisher: Academic Press
Release Date : 2017-05-12
The Endocannabinoid System written by Eric Murillo-Rodríguez and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-05-12 with Nature categories.
The Endocannabinoid System: Genetics, Biochemistry, Brain Disorders, and Therapy examines the cellular, biochemical, genetic, and therapeutic aspects of the endocannabinoid system. The chapters cover significant conceptual advances in the endocannabinoid field and shed light on the many brain disorders in which this biological system is involved. Written by world-leading experts in the field, the topics covered in this book will have a positive impact on the area of molecular biology, including, but not limited to, cell biology, neuroscience, pharmacology, signaling, disease mechanisms, and therapeutics. Provides an introduction to endocannabinoids in the central nervous system and an overview to their functions in the brain Presents information on neurobiological and cellular studies on the role of the cannabinoid signaling system and its implications in human diseases Includes well-written overviews of the basics of endocannabinoid system structure and function Contains well-illustrated material, with diagrams, charts, and tables Explores compelling case studies and their application to chapters written by experts
Cannabinoid Modulation Of Emotion Memory And Motivation
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Author : Patrizia Campolongo
language : en
Publisher: Springer
Release Date : 2015-05-18
Cannabinoid Modulation Of Emotion Memory And Motivation written by Patrizia Campolongo and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-05-18 with Medical categories.
The endocannabinoid system consists of cannabinoid receptors, their endogenous lipid ligands (endocannabinoids) and the enzymatic machinery for their synthesis and degradation. In the brain, endocannabinoids regulate ion channel activity and neurotransmitter release and thereby contribute to various aspects of brain function, including memory, reward and emotions. Their ability to modulate synaptic efficacy has a wide range of functional consequences and provides unique therapeutic possibilities. Unprecedented advances have been made in the understanding of the role of endocannabinoids in the regulation of the emotional brain over the past few years. However, a comprehensive book encompassing all these aspects is still lacking. The book will provide an overview of the role played by the endocannabinoid system in the regulation of emotional processes with particular emphasis on the modulation of memory and reward for emotionally arousing events and for the regulation of motivational aspects in cannabis use.
Cannabinoids In Health And Disease
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Author : Rosaria Meccariello
language : en
Publisher: BoD – Books on Demand
Release Date : 2016-06-15
Cannabinoids In Health And Disease written by Rosaria Meccariello and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-06-15 with Medical categories.
This book provides a comprehensive overview of current knowledge of cannabinoid activity in human physiology and points out the importance of endocannabinoid system for the maintenance of human health and treatment of diseases. Each chapter has been organized with the aim to cover basic concepts in the modulation of endocannabinoid system in both physiological and pathological conditions, thanks to the integration of data from experimental animal models and clinical observations. A special focus has been put on the medical use of cannabinoids and on the targeting of endocannabinoid system as new therapeutic strategy for the prevention and treatment of human diseases. Taken together, this book targets a wide audience of basic and clinical scientists, teachers and students interested in gaining a better understanding in the field of cannabinoids.