The Natural Killer Cell
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The Natural Killer Cell
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Author : Claire E. Lewis
language : en
Publisher: Oxford University Press, USA
Release Date : 1992
The Natural Killer Cell written by Claire E. Lewis and has been published by Oxford University Press, USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992 with Language Arts & Disciplines categories.
The ability of an organism to combat infection by foreign particles and microbial pathogens is essential for its survival and evolutionary success. Such efforts at immunity can take two forms. A considerable number of works have been published which focus on the central role of antigen recognition and antibody structure and function in the host response to infection. This volume, however, discusses the recent shift in focus towards the "natural" or "innate" immune system which consists of various cell types and factors. These cells and factors can take part in immune responses without prior sensitization, and have important modulatory effects on later, specific responses. This work reviews the biology and function of the natural killer cell, covering such topics as the molecular basis of natural killer cell function and its role in viral infection, tumor biology, and transplantation. Graduate students and researchers in immunology, cell biology, and medicine will find this work a valuable resource on current research in this exciting field.
Natural Killer Cell Protocols
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Author : Kerry S. Campbell
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-02-03
Natural Killer Cell Protocols written by Kerry S. Campbell and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-03 with Medical categories.
In Natural Killer Cell Protocols: Cellular and Molecular Methods, Kerry S. Campbell and Marco Colonna have assembled a comprehensive collection of readily reproducible methods designed to study natural killer (NK) cells from the broadest variety of viewpoints. These include not only classic techniques, but also new approaches to standard methods, newly evolved techniques that have become valuable for specific applications, and unique models for manipulating and studying NK cells. Among the advanced methods covered are those for in vitro transendothelial migration, in vivo detection of cells migrating into tumors, immunofluorescence staining of intracellular cytokines, and in vitro NK cell development. Valuable techniques for specific applications include vaccinia virus protein expression, soluble KIR-Fc fusions for HLA class I binding assays, calcium mobilization in cell conjugates, and identification of heterodimeric receptor complexes using cDNA library expression cloning. No less important are accounts of such classic methods as hybrid resistance, ADCC, viral defense, target cell cytotoxicity assays, cloning and culturing, tumor immunotherapy, and generation of HLA class I transfected target cells. Natural Killer Cell Protocols: Cellular and Molecular Methods offers immunologists, cancer researchers, virologists, and cell biologists today's most comprehensive collection of both established and cutting-edge techniques, methods that will contribute significantly to advancing our understanding of this fascinating and critically important class of cells.
Natural Killer Cells
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Author : Michael T. Lotze
language : en
Publisher: Academic Press
Release Date : 2009-11-12
Natural Killer Cells written by Michael T. Lotze and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-11-12 with Medical categories.
Natural Killer Cells explains the importance of killer cells and how they are produced. It mentions that the most likely explanation for killer cell production is that they serve as a complementary system for T cells as a primary defense against viruses. However, these cells defend against certain viruses only, such as herpes viruses and influenza viruses. The book also explains the primary functions of killer cells, and it discusses how these cells help recognize damaged tissues, limit further damage to tissues, and regenerate damaged tissues. It discusses how these cells mature and develop, and it covers the different isolation, culture, and propagation methods of these cells. Furthermore, it focuses on the different killer cells that are present in various parts of the human body. The book concludes by explaining that natural killer cells are utilized for clinical therapy of malignancies, and that they have led to positive outcomes in the field of biology and medicine. Provides a broad, detailed coverage of the biology and interactions of NK cells for students, fellows, scientists, and practitioners Includes figures, histologic sections, and illustrations of the ontogeny of NK cells
Natural Killer Cells
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Author : Eric Vivier
language : en
Publisher: Springer
Release Date : 2016-02-15
Natural Killer Cells written by Eric Vivier and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-02-15 with Medical categories.
To celebrate the 40th anniversary of the discovery of Natural Killer (NK) cells, this volume focuses on the recent advances in our understanding of NK cell development and differentiation and their acquisition of functional properties, as well as the latest models for NK-cell analysis in mice and applications in clinical medicine. NK cells have travelled a circuitous path from their initial description as ‘spontaneous killers’ (for some simply an experimental artifact) to being a bona fide subset of innate lymphoid cells with a complementary mode of action in immune defense and an important mediator of immune reactivity in health and disease. Together, these reviews provide a timely and concise picture of the evolution of NK cells as essential agents in immunity and as potent weapons against disease. This book offers an appealing and insightful resource for scientists and clinicians.
Natural Killer Cells
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Author : Srinivas S. Somanchi
language : en
Publisher: Humana Press
Release Date : 2016-05-13
Natural Killer Cells written by Srinivas S. Somanchi and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-05-13 with Medical categories.
This volume contains collection of Natural Killer Cell methodologies relevant for both basic and translational research. These methodologies present new developments in the natural killer (NK) cell field, such as understanding the influence of NK cells metabolism on its function, identifying complexity of NK cell subsets through mass cytometry, and determining the emergence of memory NK cells in murine model of MCMV infection. Methods that study NK cell migration and cytotoxicity through endpoint analysis or live single cell imaging are also discussed. Chapters also describe methods pertaining to translational application of NK cells, such as ex vivo expansion of NK cells on K562 cell lines genetically modified to express either membrane bound IL-15 or membrane bound IL-21, large scale NK cell culture, current techniques for engineering NK cells to express chimeric antigen receptors or chemokine receptors using retroviral vectors, electroporation of mRNA, and the natural phenomenon of trogocytosis. Written in the highly successful Methods in Molecular Biology series format, these chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting edge and thorough, Natural Killer Cells: Methods and Protocols is a valuable resource for researchers who not only want to understand mechanisms that govern NK cell behavior and diversity, but also for those who want to understand how to systematically evaluate NK cells for adoptive immunotherapy applications.
Natural Killer Cells
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Author : Jacques Zimmer
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-01-12
Natural Killer Cells written by Jacques Zimmer and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-01-12 with Medical categories.
Natural killer (NK) cells have been at the forefront of immunology for two decades. During that time, a great amount of information about these cells has been obtained. They are important in antiinfectious and antitumoral defense and shape the adaptive immune response. In addition, they can act as immunoregulatory cells. In recent years, the therapeutic potential of NK cells in cancer immunotherapy has become increasingly evident. This book describes in detail current knowledge about NK cells and covers a broad range of NK cell-related topics, including those that are not frequently reviewed, e.g. NK cells and allergy or NK cells and skin diseases.
Natural Killer Cells Methods And Protocols
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Author : Srinivas S. Somanchi
language : en
Publisher: Methods in Molecular Biology
Release Date : 2018-05-27
Natural Killer Cells Methods And Protocols written by Srinivas S. Somanchi and has been published by Methods in Molecular Biology this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-05-27 with Medical categories.
Immunobiology Of Natural Killer Cells
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Author : Eva Lotzova
language : en
Publisher: CRC Press
Release Date : 2019-07-23
Immunobiology Of Natural Killer Cells written by Eva Lotzova and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-07-23 with Health & Fitness categories.
First published in 1986: This book contributes to the advancing knowledge of reads in the field of NK cells, and will be helpful as a teaching device.
Natural Killer Cells
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Author : Reinhold E. Schmidt
language : en
Publisher:
Release Date : 1990
Natural Killer Cells written by Reinhold E. Schmidt and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1990 with Medical categories.
The Natural Killer Cell Interactome In The Tumor Microenvironment Basic Concepts And Clinical Application
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Author : Martin Villalba
language : en
Publisher: Frontiers Media SA
Release Date : 2020-07-02
The Natural Killer Cell Interactome In The Tumor Microenvironment Basic Concepts And Clinical Application written by Martin Villalba and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-07-02 with categories.