The Nucleus Accumbens
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The Neurobiology Of The Nucleus Accumbens
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Author : Jon F. DeFrance
language : en
Publisher: Haer Institute for Electro Physiological Research
Release Date : 1981
The Neurobiology Of The Nucleus Accumbens written by Jon F. DeFrance and has been published by Haer Institute for Electro Physiological Research this book supported file pdf, txt, epub, kindle and other format this book has been release on 1981 with Cerebellar nuclei categories.
The Nucleus Accumbens
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Author : Hélène N. David
language : en
Publisher:
Release Date : 2008-01-01
The Nucleus Accumbens written by Hélène N. David and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-01-01 with Basal ganglia categories.
The ventral part of the striatum called the nucleus accumbens is now widely recognized to play a key role in the processing of cognitive and limbic functions and the control of goal-oriented movements, both in physiological and pathophysiological conditions. At the crossroads of descending and ascending multiple neural pathways using various neurotransmitter systems, the nucleus accumbens is a complex, but fascinating, subcortical brain structure. Because of its probable critical importance in the development of psychiatric disorders, such as drug addiction and schizophrenia, much attention has been spent for the understanding of the nucleus accumbens basic mechanisms, role and functions. This new book edited by Dr. Hélène N. David comprises an impressive collection of review articles. Although not strictly divided in specific sections, the order of appearance of the selected articles will allow the reader to progress in the world of nucleus accumbens from the cellular mechanisms that underlie its neuronal functioning to its contribution to normal and pathological states, such as sensorimotor gating and executive functioning, neuropsychiatric disorders and addiction to drugs. I have no doubt these review articles by offering an individually-based global view of the nucleus accumbens roles and functions will be of great help for both scientists and students who have some interest in the field.
Role Of The Nucleus Accumbens In Feeding And Activity Related Behaviors
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Author : Xianglong Zhu
language : en
Publisher:
Release Date : 2016
Role Of The Nucleus Accumbens In Feeding And Activity Related Behaviors written by Xianglong Zhu and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016 with categories.
The Nucleus Accumbens
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Author : Erin C. Kerfoot
language : en
Publisher:
Release Date : 2009
The Nucleus Accumbens written by Erin C. Kerfoot and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with categories.
The Nucleus Accumbens And Subpallidal Areas
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Author : Rudi van den Bos
language : en
Publisher:
Release Date : 1991
The Nucleus Accumbens And Subpallidal Areas written by Rudi van den Bos and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991 with categories.
The Action Of Dopamine In The Nucleus Accumbens On Avoidance Behaviour In The Rat
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Author : Peter Bracs
language : en
Publisher:
Release Date : 1982
The Action Of Dopamine In The Nucleus Accumbens On Avoidance Behaviour In The Rat written by Peter Bracs and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1982 with Avoidance (Psychology) categories.
The Role Of The Nucleus Accumbens In The Mediation Of Conditioned Fear
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Author : Tatiana Haralambous
language : en
Publisher:
Release Date : 2000
The Role Of The Nucleus Accumbens In The Mediation Of Conditioned Fear written by Tatiana Haralambous and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000 with Basal ganglia categories.
Dopamine Receptors In The Nucleus Accumbens
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Author : Ana Lúcia Rêlo
language : en
Publisher:
Release Date : 1994
Dopamine Receptors In The Nucleus Accumbens written by Ana Lúcia Rêlo and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994 with categories.
Afferent Information Processing In The Nucleus Accumbens
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Author : John A. Wolf
language : en
Publisher:
Release Date : 2006
Afferent Information Processing In The Nucleus Accumbens written by John A. Wolf and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with categories.
The Nucleus Accumbens (NAcb), part of the ventral striatum in the basal ganglia, processes afferent input from many of the cognitive and limbic areas of the brain, including the prefrontal cortex (PFC), hippocampus (HC), amygdala, and thalamus. Altered processing in this region of the brain has been hypothesized to underlie disorders such as schizophrenia and addiction. The central question of this thesis is how the inputs to the NAcb are processed by the major cell in the NAcb, the medium spiny projection neurons (MSPs). In order to investigate this problem, we developed a computational model of the cell and examined its response to afferent inputs, as well as recording responses of these cells to stimulation of afferent inputs in the awake rat. The model neuron, constructed in NEURON, was tuned by adjusting maximal current conductances in each compartment until the model cell closely matched whole cell recordings from an adult rat NAcb slice preparation. Synaptic inputs in the range of 1000-1300 Hz are required to maintain an "up" state in the model. As NMDA:AMPA current ratios were increased, the membrane showed an increase in hysteresis of "up" and "down" state dwell times, however intrinsic bistability was not observed. Altering the NMDA:AMPA ratio had a profound effect on processing of afferent input, including the ability to entrain to oscillations in afferent input in the theta range (4-12 Hz). To investigate the hypothesis that PFC inputs to the NAcb are gated by HC inputs, we extended previous studies in anesthetized rats by comparing the response to various combinations of PFC and HC stimulation in the awake and the isoflurane anesthetized, chronically implanted rats. Contrary to previous findings, we found that summation of afferent input in the NAcb is sublinear, with only a minority of neurons demonstrating gating of the PFC inputs via the HC in the awake or the anesthetized animal. These results suggest that sublinear integration of afferent inputs is the dominant profile in the response of NAcb cells in the awake animal.
The Nucleus Accumbens
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Author : Adrianus Johannes Josephus Pijnenburg
language : en
Publisher:
Release Date : 1976
The Nucleus Accumbens written by Adrianus Johannes Josephus Pijnenburg and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1976 with categories.