The Pharmacology Of Monoclonal Antibodies
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The Pharmacology Of Monoclonal Antibodies
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Author : Martin Rosenberg
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
The Pharmacology Of Monoclonal Antibodies written by Martin Rosenberg and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
A sample of the most exciting developments in the cloning, manipulation, expression and application of genetically-engineered monoclonal antibodies. This rapidly-evolving field has witnessed the PCR combinatorial cloning of vast immunological diversity, in vitro mutagenesis of MAbs, MAbs created by transgenic animals, novel expression systems in plants, animals and lower systems, as well as a rich variety of genetically modified MAbs as potential therapeutic agents. Leading scientists from academia and industry present their own findings as well as short reviews of these research areas.
The Pharmacology Of Monoclonal Antibodies
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Author : Martin Rosenberg
language : en
Publisher:
Release Date : 1994-06-24
The Pharmacology Of Monoclonal Antibodies written by Martin Rosenberg and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994-06-24 with categories.
A sample of the most exciting developments in the cloning, manipulation, expression and application of genetically-engineered monoclonal antibodies. This rapidly-evolving field has witnessed the PCR combinatorial cloning of vast immunological diversity, in vitro mutagenesis of MAbs, MAbs created by transgenic animals, novel expression systems in plants, animals and lower systems, as well as a rich variety of genetically modified MAbs as potential therapeutic agents. Leading scientists from academia and industry present their own findings as well as short reviews of these research areas.
The Pharmacology Of Monoclonal Antibodies
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Author : Martin Rosenberg
language : en
Publisher: Springer
Release Date : 1994-06-24
The Pharmacology Of Monoclonal Antibodies written by Martin Rosenberg and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994-06-24 with Medical categories.
A sample of the most exciting developments in the cloning, manipulation, expression and application of genetically-engineered monoclonal antibodies. This rapidly-evolving field has witnessed the PCR combinatorial cloning of vast immunological diversity, in vitro mutagenesis of MAbs, MAbs created by transgenic animals, novel expression systems in plants, animals and lower systems, as well as a rich variety of genetically modified MAbs as potential therapeutic agents. Leading scientists from academia and industry present their own findings as well as short reviews of these research areas.
Antibody Drug Discovery
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Author : Clive R. Wood
language : en
Publisher: World Scientific
Release Date : 2012
Antibody Drug Discovery written by Clive R. Wood and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with Medical categories.
Antibody-based therapeutics are a central driver of the success of biopharmaceuticals. The discovery technology of this field is isolated to a limited number of centers of excellence in industry and academia. The objective of this volume is to provide a series of guides to those evaluating and preparing to enter particular areas within the field. Each chapter is written with a historical perspective that sets into context the significance of the key developments, and with the provision of “points to consider” for the reader as a value-added feature of the volume. All contributors are experts in their fields and have played pivotal roles in the creation of the technology.
Applications And Engineering Of Monoclonal Antibodies
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Author : David J. King
language : en
Publisher: CRC Press
Release Date : 1998-11-27
Applications And Engineering Of Monoclonal Antibodies written by David J. King and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998-11-27 with Medical categories.
A valuable resource for researchers and workers in the fields of both pharmaceuticals and biotechnology as well as undergraduates in biochemistry, applied biology, biomedical sciences and pharmacy, this book compares established techniques of antibody production with the new. Antibody structure and the implications of antibody engineering are fully discussed, and a case study approach illustrates how antibodies are finding increasing use in the diagnosis and treatment of disease. The volume ends with commercial expression, purification and large-scale manufacture of antibodies and their future potential, particularly as therapeutic agents.
Monoclonal Antibodies In Drug Development
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Author : J. Thomas August
language : en
Publisher:
Release Date : 1982
Monoclonal Antibodies In Drug Development written by J. Thomas August and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1982 with Medical categories.
Current Trends In Monoclonal Antibody Development And Manufacturing
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Author : Steven J. Shire
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-11-11
Current Trends In Monoclonal Antibody Development And Manufacturing written by Steven J. Shire and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-11-11 with Medical categories.
Monoclonal antibodies represent one of the fastest growing areas of new drug development within the pharmaceutical industry. Several blockbuster products have been approved over the past several years including Rituxan, Remicade, Avastin, Humira, and Herceptin. In addition, over 300 new drugs are currently in clinical trials. With both large, established biotechnology companies and small start-ups involved in the development of this important class of molecules, monoclonal antibodies products will become increasingly prevalent over the next decade. Recently the regulatory review of monoclonal antibodies has been moved from Center for Biologics and Research to the Center for Drug Evaluation and Research (CDER) division of the US Food and Drug Administration. It is anticipated that CDER will expect a certain minimal amount of data to be provided as more of these products move through the regulatory pipeline. Current Trends in Monoclonal Antibody Development and Manufacturing will provide readers with an understanding of what is currently being done in the industry to develop, manufacture, and release monoclonal antibody products and what will be required for a successful regulatory submission.
Therapeutic Monoclonal Antibodies
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Author : James W. Larrick
language : en
Publisher: Springer
Release Date : 1990-06-18
Therapeutic Monoclonal Antibodies written by James W. Larrick and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 1990-06-18 with Medical categories.
A review of therapeutic antibodies which have commercial potential. It discusses PCR cloning of Igs, immortalization by gene transfer, scale up production, infectious diseases, viruses, bacteria, parisites, inflammation/immunology, blood grouping, cells, cytokines, tumours and MDR.
Development Of Antibody Based Therapeutics
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Author : Mohammad A. Tabrizi
language : en
Publisher: Springer
Release Date : 2018-09-11
Development Of Antibody Based Therapeutics written by Mohammad A. Tabrizi and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-09-11 with Medical categories.
With a key focus on recent developments and advances in the field, this book provides in-depth coverage of topics fundamental to the development of targeted therapeutics. The expansion of targeted modalities in rapidly evolving therapeutic areas, such as immune-oncology, and developments with respect to combination therapies, novel technologies, and the therapeutic application of antibody-drug conjugates, are presented. Additionally, the book builds upon topics discussed in the first edition (2012) where recent innovations warrant elaboration. This, the second edition of Development of Antibody-Based Therapeutics: Translational Considerations, represents a comprehensive evaluation of progress in the field, which sits alongside the first edition to inform, in detail, professional and academic researchers, as well as graduate students.
Immunopharmacology
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Author : Manzoor M. Khan
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-12-19
Immunopharmacology written by Manzoor M. Khan and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-12-19 with Medical categories.
During the past decades, with the introduction of the recombinant DNA, hybridoma and transgenic technologies there has been an exponential evolution in understanding the pathogenesis, diagnosis and treatment of a large number of human diseases. The technologies are evident with the development of cytokines and monoclonal antibodies as therapeutic agents and the techniques used in gene therapy. Immunopharmacology is that area of biomedical sciences where immunology, pharmacology and pathology overlap. It concerns the pharmacological approach to the immune response in physiological as well as pathological events. This goals and objectives of this textbook are to emphasize the developments in immunology and pharmacology as they relate to the modulation of immune response. The information includes the pharmacology of cytokines, monoclonal antibodies, mechanism of action of immune-suppressive agents and their relevance in tissue transplantation, therapeutic strategies for the treatment of AIDS and the techniques employed in gene therapy. The book is intended for health care professional students and graduate students in pharmacology and immunology.