The Pituitary Transcription Factor Pit 1
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The Pituitary Transcription Factor Pit 1
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Author : Ruoping Chen
language : en
Publisher:
Release Date : 1992
The Pituitary Transcription Factor Pit 1 written by Ruoping Chen and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992 with categories.
Pit 1 A Pou Domain Transcription Factor In Development Of The Anterior Pituitary Gland
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Author : Sen Li
language : en
Publisher:
Release Date : 1992
Pit 1 A Pou Domain Transcription Factor In Development Of The Anterior Pituitary Gland written by Sen Li and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992 with categories.
Structural And Functional Studies On The Pituitary Specific Transcription Factor Pit 1
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Author : Kevin Dennis Augustijn
language : en
Publisher:
Release Date : 2002
Structural And Functional Studies On The Pituitary Specific Transcription Factor Pit 1 written by Kevin Dennis Augustijn and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with categories.
The Chicken Pituitary Specific Transcription Factor Pit 1
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Author : Pieter Van As
language : en
Publisher: LAP Lambert Academic Publishing
Release Date : 2010-01-26
The Chicken Pituitary Specific Transcription Factor Pit 1 written by Pieter Van As and has been published by LAP Lambert Academic Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-01-26 with categories.
During mammalian anterior pituitary development, the pituitary-specific transcription factor Pit-1 has an important role in the regulation of the initial expression of GH, PRL, and TSHbeta encoding genes and in the development of the lactotropes, somatotropes and thyrotropes which produce PRL, GH, and TSH respectively. It is also known that Pit-1 is involved in the hypothalamic regulation of these pituitary hormones, both at pre- and postnatal stages. However, little is known about the structure, the initial expression and the regulatory functions of Pit-1 in avian species. In this work, the structure and the initial appearance of the chicken Pit-1 gene, and its involvement in the hypothalamic regulation of pituitary hormones are described. A newly developed quantitative assay is described which allows the study of the regulatory role of Pit-1 within the hypothalamus-pituitary axis in chicken. The results and hypotheses presented in this book should be useful to unravel even more of the complex interactions between the hypothalamus, the pituitary and several endocrine organs.
Pituitary Specific Transcription Factor Pit 1 In Chinese Grass Carp
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Author :
language : en
Publisher:
Release Date : 2004
Pituitary Specific Transcription Factor Pit 1 In Chinese Grass Carp written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with categories.
(Uncorrected OCR) Abstract of thesis entitled PITUITARY-SPECIFIC TRANSCRIPTION FACTOR PIT-1 IN CHINESE GRASS CARP: MOLECULAR CLONING, FUNCTIONAL CHARACTERIZATION, AND REGULATION OF ITS TRANSCRIPT EXPRESSION AT THE PITUITARY LEVEL Submitted by Kwong Ka Yee for the degree of Master of Philosophy at The University of Hong Kong in January 2004 Pituitary-specific transcription factor-1 (Pit-l/GHF-1), a Pit-Oct-Unc (POU) family transcription factor, is known to be essential for the pituitary specific expression of prolactin and growth hormone (GH). Although the functional role of Pit-1 at the pituitary level has been well established in mammals, the neuroendocrine mechanisms regulating Pit-1 gene expression have not been fully characterized. In lower vertebrates, such as fish, it is still unclear if Pit-1 expression at the pituitary level can be regulated by hypothalamic factors. In this study, a Pit-1 cDNA was cloned in Chinese grass carp, Ctenopharyngodon idellus using 5' and 3' Rapid Amplification of cDNA Ends (RACE). Sequence analysis has revealed that this Pit-1 cDNA has a 55 bp 5' untranslated region, a 1071 bp open reading frame encoding 356 amino acids, and a 941 bp 3' untranslated region. The amino acid sequence of the encoded protein contains Serine/Threonine-rich activation (STA) domain with both B and j inserts, POU-specific domain and POU-homeodomain which are highly homologous to Pit-1 reported in other fish species. Using Northern blot and RT-PCR, a 3.5 Kb Pit-1 transcript was identified exclusively in the pituitary but not in other tissues in Chinese grass carp. Genomic Southern analysis also revealed that there were two copies of Pit-1 gene in the grass carp genome. To confirm the functional identity of grass carp Pit-1, overexpression of this newly cloned cDNA was conducted in mammalian cell lines transfected with a luciferase reporter construct carrying the 5' promoter of grass carp growth hormone (GH) gene. In these experiments, luciferase activity was.
Functional And Distribution Studies Of Isoforms Of The Pituitary Specific Transcription Factor Pit 1
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Author : Brian Kloss
language : en
Publisher:
Release Date : 1995
Functional And Distribution Studies Of Isoforms Of The Pituitary Specific Transcription Factor Pit 1 written by Brian Kloss and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995 with categories.
Cell Type Specific Transcription Of Genes In The Anterior Pituitary Gland
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Author : Kathleen Mary Scully
language : en
Publisher:
Release Date : 1996
Cell Type Specific Transcription Of Genes In The Anterior Pituitary Gland written by Kathleen Mary Scully and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996 with categories.
Molecular Cloning Of The Chicken Pituitary Specific Transcription Factor Pit 1 And The Involvement In The Hypothalamic Regulation Of Pituitary Hormones
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Author : Pieter Van As
language : en
Publisher:
Release Date : 2005
Molecular Cloning Of The Chicken Pituitary Specific Transcription Factor Pit 1 And The Involvement In The Hypothalamic Regulation Of Pituitary Hormones written by Pieter Van As and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with categories.
Molecular Cloning Of The Chicken Pituitary Specific Transcription Factor Pit 1 And The Involvement In The Hypothlamic Regulation Of Pituitary Hormones
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Author : Pieter van As
language : en
Publisher:
Release Date : 2005
Molecular Cloning Of The Chicken Pituitary Specific Transcription Factor Pit 1 And The Involvement In The Hypothlamic Regulation Of Pituitary Hormones written by Pieter van As and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with categories.
New Insights To Neuroimmune Biology
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Author : Istvan Berczi
language : en
Publisher: Elsevier
Release Date : 2010-05-27
New Insights To Neuroimmune Biology written by Istvan Berczi and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-05-27 with Science categories.
New Insights to Neuroimmune Biology investigates the mechanisms that and functions of the Neuroimmune Regulatory Supersystem. Covering molecular regulation of cytokines in brain astrocytes, immunoregulation by the sympathetic nervous system, circadian regulation of immune reactions, antigen recognition by the CNS, the modulation of the immune response by head injury, neurogenic inflammation, the role of tachykinins in asthma and allergic disease, defence and defeat reactions, cytokines, behavior and affective disorders, increased activity of type 1 helper T cell functions after reward stimulation. This book has relevance to the entire scientific community in Biology, Medicine and Veterinary medicine as it discusses molecular, cellular, organic and systemic aspects as well as the physological, pathophysiological and behavioral mechnisms which are involved in Neuroimmiune Biology.