The Prot G
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G Protein Signaling
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Author : Alan V. Smrcka
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-02-02
G Protein Signaling written by Alan V. Smrcka and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-02 with Science categories.
Alan V. Smrcka presents a collection of cutting-edge methods for investigating G protein signaling from a variety of perspectives ranging from in vitro biochemistry to whole animal studies. Among the readily reproducible techniques presented are those for the purification of G proteins and effectors enzymes, assays of these purified G proteins and effector enzymes, and for the study of G proteins interactions with effectors in intact cells. Additional methods are provided for assaying G protein coupled receptor structure, function, and localization, and for studying the physiological roles for endogenous G proteins.
G Protein Coupled Receptors
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Author : Tiina P. Iismaa
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-29
G Protein Coupled Receptors written by Tiina P. Iismaa and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-29 with Science categories.
This book is about the recent advances in the structural and functional characterization of receptors that influence intracellular signalling events through interaction with intracellular GTP-binding proteins (G proteins). Molecular cloning of members of the G protein-coupled receptor superfamily has complemented pharmacological investigations in providing a realization of the structural and functional diversity of these receptors. An increased understanding of the involvement of particular receptor subtypes in normal and pathophysiological processes represents exciting possibilities for the development of highly specific and effective therapeutic agents.
Mechanisms And Pathways Of Heterotrimeric G Protein Signaling
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Author : Stephen Sprang
language : en
Publisher: Academic Press
Release Date : 2007-10-01
Mechanisms And Pathways Of Heterotrimeric G Protein Signaling written by Stephen Sprang and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-10-01 with Science categories.
This volume in the Advances in Protein Chemistry series features cutting-edge articles on topics in protein chemistry. This volume includes chapters on the structural basis of effector regulation and signal termination in heterotrimeric Gƒуnƒnproteins; How do receptors activate G proteins; Some mechanistic insights into GPCR activation from detergent solubilized ternary complexes on beads; Activation of G protein coupled receptors; Kinetic analysis of g-protein-coupled receptor signaling using fluorescence resonance energy transfer in living cells; Regulation of Rho Guanine Nucleotide Exchange Factors (RhoGEFs) by G proteins.
G Protein Pathways Part B G Proteins And Their Regulators
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Author :
language : en
Publisher: Elsevier
Release Date : 2001-12-18
G Protein Pathways Part B G Proteins And Their Regulators written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-12-18 with Science categories.
This volume covers topics such as the structure and identification of functional domains of G proteins, and activation of G proteins by receptors or other regulators. The text takes an integrated approach to studying common experimental questions at many different levels related to G proteins. Methods related to G proteins using molecular modeling, systems biology, protein engineering, protein biochemistry, cell biology, and physiology are all accessible in the same volume. The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today truly an essential publication for researchers in all fields of life sciences.
G Protein Coupled Receptors
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Author : David Poyner
language : en
Publisher: John Wiley & Sons
Release Date : 2009-12-11
G Protein Coupled Receptors written by David Poyner and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-12-11 with Science categories.
G-Protein Coupled Receptors (GPCRs) are not only the largest protein family in the human genome but are also the single biggest target for therapeutic agents. Research into GPCRs is therefore growing at a fast pace and the range of techniques that can be applied to GPCRs is vast and continues to grow. This book provides an invaluable bench-side guide into the best and most up-to-date techniques for current and future research on GPCRs. With contributions from leading international authorities, this book equips readers with clear and detailed protocols for both well-known and up-and-coming techniques along with hints and tips for success. All the methods have been tried and tested by leading international research labs and are presented in easy-to-follow stages along with a useful overview of each technique. This book is an essential resource for all researchers in molecular biology, biochemistry, pharmacology and for graduate students.
Regulators Of G Protein Signaling
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Author :
language : en
Publisher: Elsevier
Release Date : 2004-11-25
Regulators Of G Protein Signaling written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-11-25 with Science categories.
Regulators of G Protein Signaling, Part A is an in-depth treatment of G-Protein Signaling, and will cover general methods of analysis of RGS protein analysis, including Expression and post-translational modification, Assays of GAP activity and allosteric control, Electrophysiological methods and RGS-insensitive Ga subunits, Mouse models of RGS protein action, Methods of RGS protein inhibition, and G-protein regulators of model organisms. Table of Contents Expression and post-translational modification Assays of GAP activity and allosteric control Electrophysiological methods and RGS-insenstitive Ga subunits Mouse Models of RGS protein action Methods of RGS protein inhibition G-protein regulators of model organisms
G Protein Coupled Receptor Dimers
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Author : Katharine Herrick-Davis
language : en
Publisher: Springer
Release Date : 2017-08-31
G Protein Coupled Receptor Dimers written by Katharine Herrick-Davis and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-08-31 with Medical categories.
G-protein-coupled receptors (GPCRs) are believed to be the largest family of membrane proteins involved in signal transduction and cellular responses. They dimerize (form a pair of macromolecules) with a wide variety of other receptors. The proposed book will provide a comprehensive overview of GPCR dimers, starting with a historical perspective and including, basic information about the different dimers, how they synthesize, their signaling properties, and the many diverse physiological processes in which they are involved. In addition to presenting information about healthy GPCR dimer activity, the book will also include a section on their pathology and therapeutic potentials.
Heterotrimeric G Protein Effectors
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Author : Ravi Iyengar
language : en
Publisher: Elsevier
Release Date : 1994-09-08
Heterotrimeric G Protein Effectors written by Ravi Iyengar and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994-09-08 with Medical categories.
This volume of Methods in Enzymology and its companion Volume 237 include molecular, biological, and biochemical methods for the study of cell surface heterotrimeric G proteins and their effectors. Methods unique to signal transducing G proteins and general techniques that have been applied to the study of G protein systems are covered.
Signal Transduction By G Protein Coupled Receptors
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Author : Paul H.J. Nederkoorn
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-29
Signal Transduction By G Protein Coupled Receptors written by Paul H.J. Nederkoorn and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-29 with Medical categories.
G Protein Coupled Receptors
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Author : Gabriel Berstein
language : en
Publisher: CRC Press
Release Date : 2019-04-24
G Protein Coupled Receptors written by Gabriel Berstein and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-04-24 with Medical categories.
Covering recently developed methods in membrane-bound receptors, this book emphasizes receptor structure and function, knowledge of which is essential to the study of signal transduction. G Protein-Coupled Receptors has culled contributors from domestic and international sources, providing a broad base of knowledge. Some topics covered are the r