The Receptors
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The Receptors
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Author : P. Michael Conn
language : en
Publisher: Academic Press
Release Date : 2014-05-10
The Receptors written by P. Michael Conn and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-10 with Science categories.
The Receptors, Volume II deals with receptors for somatostatin, vitamin D, insulin, and animal viruses, as well as for the ?2-adrenergic and Ah systems. The significance of translational modifications of receptor ligands is discussed, along with the mechanisms of receptor-ligand interactions. The role of receptors in development and their regulation by tumors are also considered. Comprised of 12 chapters, this volume begins with a detailed account of the vitamin D receptor, paying particular attention to its biochemical and physical properties as well as its mechanism of action. The discussion then turns to experimental discrimination between alternative mechanistic models for the receptor-mediated stimulation of adenylate cyclase; the role of microaggregation in hormone-receptor-effector interactions; and the biology and biochemistry of the Ah receptor. Subsequent chapters explore the interactions of animal viruses with cell surface receptors; insulin receptors; determination of the size of neurotransmitter receptors by radiation inactivation-target size analysis; and protein glycosylation and receptor-ligand interactions. This book will be a valuable resource for students and practitioners in fields ranging from cell biology and biochemistry to physiology, endocrinology, and pharmacology.
The Receptors
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Author : P. Michael Conn
language : en
Publisher: Academic Press
Release Date : 2014-05-10
The Receptors written by P. Michael Conn and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-10 with Science categories.
The Receptors, Volume IV deals with receptors for intracellular hormones, estrogen, and sex steroids as well as for dopamine, cholecystokinin, and corticotropin. The role of surface recognition receptors in disease is also discussed, along with receptors for plant auxin action and auxin transport. Comprised of 11 chapters, this volume begins with a detailed account of the ?-adrenergic receptor-coupled adenylate cyclase and the reconstitution of the functional interactions of its various purified components. The discussion then turns to the mechanism of action of steroid and thyroid hormones and how abnormalities in their receptors lead to disease; nuclear location of estrogen receptors; and the biochemistry of the fungal sex steroid receptors as well as the use of Achlya as a model system for the study of the mechanism of action of steroid hormones in general. Subsequent chapters focus on dopamine receptors; cholecystokinin receptor; corticotropin receptors; and the search for receptors that mediate sweetness. The book concludes with an analysis of endocrine receptors on lymphocytes and the integration of endocrine and immune systems, with emphasis on large granular lymphocytes. This monograph will be a valuable resource for students and practitioners in fields ranging from cell biology and biochemistry to physiology, endocrinology, and pharmacology.
The Receptors
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Author : P. Michael Conn
language : en
Publisher: Academic Press
Release Date : 2014-05-10
The Receptors written by P. Michael Conn and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-10 with Medical categories.
The Receptors, Volume III deals with receptors for interferons, hormones, and growth factors as well as for ?-aminobutyric acid, tuftsin, somatomedin, and insulin. Prolactin and nicotine receptors are also considered, along with the protein tyrosine kinase activity of hormone and growth factor receptors. Comprised of 12 chapters, this volume begins with a detailed account of secretory component (SC) as a receptor for polymeric immunoglobulins and the importance of SC-polymeric immunoglobulin A interactions in the mucosal immune system. The discussion then turns to interferon receptors and what is known about the fate of interferons and their receptors after binding; the use of muscimol in ligand-binding studies aimed at characterizing ?-aminobutyric acid receptors; and the role of protease nexins in the interaction of proteases with cells and in the regulation of proteolytic activity in the interstitial fluid immediately surrounding cells. Subsequent chapters focus on receptor regulation of phosphoinositides and calcium; effects of phospholipid turnover on receptor function; dynamics of tuftsin receptors; and the structure, function, and regulation of somatomedin receptors. The book also examines the internalization and intracellular processing of insulin receptors before concluding with an analysis of prolactin and nicotine receptors. This monograph will be a valuable resource for students and practitioners in fields ranging from cell biology and biochemistry to physiology, endocrinology, and pharmacology.
The Adrenergic Receptors
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Author : Dianne M. Perez
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-10-28
The Adrenergic Receptors written by Dianne M. Perez and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-10-28 with Medical categories.
An authoritative review of the current state-of-the-art understanding of the structure and function of the adrenergic receptor subtypes, as well as of the role played by these receptors in physiological and pathophysiological settings. Topics range from structure-function studies and the imaging of adrenergic receptors to the use of genetically altered mouse models and pharmacogenomics. Highlights include a survey of the knockout and overexpressed mouse models, a review of the new ways that adrenergic receptors can signal, and the effects of polymorphisms on clinical outcomes and on potential gene therapy applications. The side-by-side comparison of all the adrenergic receptors (a1, a2, and b) provides the reader with an excellent survey of the field, including the rationale for designing better drugs to control blood pressure and heart function.
The Receptors
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Author : Richard D. O'Brien
language : en
Publisher: Springer Science & Business Media
Release Date : 1979
The Receptors written by Richard D. O'Brien and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 1979 with Binding sites (Biochemistry) categories.
The Receptors
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Author : P. Michael Conn
language : en
Publisher:
Release Date : 1984
The Receptors written by P. Michael Conn and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1984 with Cell receptors categories.
Receptors In The Developing Nervous System
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Author : Ian S. Zagon
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Receptors In The Developing Nervous System written by Ian S. Zagon and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Receptors for cell hormones, growth factors, Fourth, alterations in the development of neu and neurotransmitters are involved in the ral receptors may have profound implications control and modulation of an enormous array for the structure and function of the of biological processes. The development of organism. As much as possible, the reper these receptors has distinct spatial and tem cussions of disrupting the orchestration of poral arrangements, and alterations in this receptor development in the nervous system pattern during embryogenesis can have signi are discussed. In many instances, however, ficant consequences for the well-being of the we are just beginning to learn about some fetus, infant, child and adult. The developing receptors and the authors may not be in a nervous system is particularly dependent on position to discuss the consequences of recep receptors because its period of structural and tor dysfunction. functional organization extends through both In designing these two volumes, we have prenatal and postnatal phases. Moreover, asked major figures in each field to review the receptors are a key element in neural com literature, to apprise the audience of their munication in both the developing and adult latest findings, and to provide a perspective on organism, so that the ontogeny of receptors is the role of receptors in the developing nervous crucial in determining the myriad connections system. These books are intended to sum forming the circuitry of the nervous system.
Receptors In The Human Nervous System
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Author : F. A. O. Mendelsohn
language : en
Publisher: Academic Press
Release Date : 2013-10-22
Receptors In The Human Nervous System written by F. A. O. Mendelsohn and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-22 with Medical categories.
Receptors in the Human Nervous System is a synthesis of the results of receptor mapping by leaders in the field. In addition to a comprehensive discussion of the distribution and possible interactions of the receptors of different neuroactive substances, this book also contains an abundance of pictorial representations of receptor distributions. High-quality photographs of one receptor are often juxtaposed with photographs of the distribution of a different receptor or receptor subtype for the consideration of possible interactions between different systems. The book surveys the distribution of receptor subtypes for the classical monoamine transmitters (acetylcholine, adrenaline, noradrenaline and serotonin) as well as the distribution of receptors for the excitatory and inhibitory amino acids, (glutamate, GABA and benzodiazepines) as well as the opioid peptides, angiotensen and other neuropeptides. The distribution of multiple types of serotonin receptors is given in detail, and the codistribution of receptors in the cortex is discussed. The book is directed toward researchers in the field of chemical neuroanatomy, as well as pharmacologists, neurophysiologists, and neuroscientists.
The Beta Adrenergic Receptors
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Author : John P. Perkins
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
The Beta Adrenergic Receptors written by John P. Perkins and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
The Serotonin Receptors
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Author : Bryan L. Roth
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-08-17
The Serotonin Receptors written by Bryan L. Roth and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-08-17 with Medical categories.
A comprehensive, state-of-the-art review of our current understanding of the molecular and structural biology of 5-HT receptors and their potential use for drug discovery. The authors describe the anatomical, cellular, and subcellular distribution of 5-HT receptors and demonstrate a powerful approach to elucidating their physiological role using knockout mice in which the 5-HT receptors were deleted. They also review our understanding of the physiological role(s) of 5-HT receptors based mainly on studies performed in genetically engineered mice. Highlights include discussions of the behavioral phenotypes of 5-HT receptor knockout animals, the molecular biology and pharmacology of 5-HT receptors, and insights into the complexity of 5-HT receptor signal transduction.