The Regulation Of Cerebral Blood Flow
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Cerebral Blood Flow In Acute Head Injury
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Author : Georg E. Cold
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Cerebral Blood Flow In Acute Head Injury written by Georg E. Cold and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
During the last decade a multitude of studies concerning the dynamic changes in cerebral blood flow (CBF), cerebral metabolic rate of oxygen (CMRO2), and intracranial pressure (ICP) in the acute phase after head injury have been published. These studies have been supplemented with studies of cerebral autoregulation, CO2 reactivity and barbiturate reactivity. Other investigations include studies of cerebrospinal fluid pH, bicarbonate, lactate and pyruvate. In this book experimental and clinical studies of the dynamic changes in CBF, CMRO2, CO2 reactivity and barbiturate reactivity are reviewed. The author's own clinical studies of the dynamic changes in CBF and cerebral metabolism are summarized and discussed, and the therapeutical implication as regards the use of artificial hyperventilation, sedation with barbiturate and mannitol treatment are discussed.
The Cerebral Circulation
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Author : Marilyn J. Cipolla
language : en
Publisher: Biota Publishing
Release Date : 2016-07-28
The Cerebral Circulation written by Marilyn J. Cipolla and has been published by Biota Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-07-28 with Medical categories.
This e-book will review special features of the cerebral circulation and how they contribute to the physiology of the brain. It describes structural and functional properties of the cerebral circulation that are unique to the brain, an organ with high metabolic demands and the need for tight water and ion homeostasis. Autoregulation is pronounced in the brain, with myogenic, metabolic and neurogenic mechanisms contributing to maintain relatively constant blood flow during both increases and decreases in pressure. In addition, unlike peripheral organs where the majority of vascular resistance resides in small arteries and arterioles, large extracranial and intracranial arteries contribute significantly to vascular resistance in the brain. The prominent role of large arteries in cerebrovascular resistance helps maintain blood flow and protect downstream vessels during changes in perfusion pressure. The cerebral endothelium is also unique in that its barrier properties are in some way more like epithelium than endothelium in the periphery. The cerebral endothelium, known as the blood-brain barrier, has specialized tight junctions that do not allow ions to pass freely and has very low hydraulic conductivity and transcellular transport. This special configuration modifies Starling's forces in the brain microcirculation such that ions retained in the vascular lumen oppose water movement due to hydrostatic pressure. Tight water regulation is necessary in the brain because it has limited capacity for expansion within the skull. Increased intracranial pressure due to vasogenic edema can cause severe neurologic complications and death.
The Cerebral Circulation
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Author : Marilyn J. Cipolla
language : en
Publisher: Morgan & Claypool Publishers
Release Date : 2010
The Cerebral Circulation written by Marilyn J. Cipolla and has been published by Morgan & Claypool Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010 with Anatomy categories.
This presentation describes structural and functional properties of the cerebral circulation that are unique to the brain, an organ with high metabolic demands, and the need for tight water and ion homeostasis. Autoregulation is pronounced in the brain, with myogenic, metabolic, and neurogenic mechanisms contributing to maintain relatively constant blood flow during both increases and decreases in pressure. In addition, unlike peripheral organs where the majority of vascular resistance resides in small arteries and arterioles, large extracranial and intracranial arteries contribute significantly to vascular resistance in the brain. The prominent role of large arteries in cerebrovascular resistance helps maintain blood flow and protect downstream vessels during changes in perfusion pressure. The cerebral endothelium is also unique in that its barrier properties are in some way more like epithelium than endothelium in the periphery. The cerebral endothelium, known as the blood-brain barrier, has specialized tight junctions that do not allow ions to pass freely and has very low hydraulic conductivity and transcellular transport. This special configuration modifies Starling's forces in the brain such that ions retained in the vascular lumen oppose water movement due to hydrostatic pressure. Tight water regulation is necessary in the brain because it has limited capacity for expansion within the skull. Increased intracranial pressure due to vasogenic edema can cause severe neurologic complications and death. This chapter will review these special features of the cerebral circulation and how they contribute to the physiology of the brain. Table of Contents: Introduction / Anatomy and Ultrastructure / Perivascular Innervation / Regulation of Cerebrovascular Tone / Control of Cerebral Blood Flow / Barriers of the CNS / Summary / References
The Regulation Of Cerebral Blood Flow
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Author : John W. Phillis
language : en
Publisher: CRC Press
Release Date : 1993-07-06
The Regulation Of Cerebral Blood Flow written by John W. Phillis and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993-07-06 with Medical categories.
The Regulation of Cerebral Blood Flow presents a comprehensive review of recent literature on the mechanisms by which cerebral blood flow is matched to the metabolic requirements of the brain. Topics covered include techniques for monitoring cerebral blood flow; the intrinsic properties of cerebral vascular smooth muscle fibers; the neuronal regulation of vascular tone; metabolic factors released by brain cells; and changes in cerebral blood flow regulation in the neonate and aged, diabetics, hypertensives, and migraineurs. The book will benefit neurologists, neurosurgeons, physiologists, pharmaceutical manufacturers, and others interested in this critical area of vascular function.
Brain And Blood Flow
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Author : Ralph William Ross Russell
language : en
Publisher:
Release Date : 1971
Brain And Blood Flow written by Ralph William Ross Russell and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1971 with Medical categories.
Regulation Of Cerebral Blood Flow
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Author : Alexander David Mendelow
language : en
Publisher:
Release Date : 1978
Regulation Of Cerebral Blood Flow written by Alexander David Mendelow and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1978 with categories.
Regulation Of Cerebral Blood Flow With Emphasis On Age And Environment
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Author :
language : en
Publisher:
Release Date : 2015
Regulation Of Cerebral Blood Flow With Emphasis On Age And Environment written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015 with categories.
The Regulation Of Cerebral Blood Flow During Wakefulness And Sleep In Humans
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Author :
language : en
Publisher:
Release Date : 2005
The Regulation Of Cerebral Blood Flow During Wakefulness And Sleep In Humans written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with categories.
Basic Physiology For Anaesthetists
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Author : David Chambers
language : en
Publisher: Cambridge University Press
Release Date : 2019-07-25
Basic Physiology For Anaesthetists written by David Chambers and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-07-25 with Medical categories.
Easily understood, up-to-date and clinically relevant, this book provides junior anaesthetists with an essential physiology resource.
Cerebral Blood Flow Methods For Measurement Regulation Effects Of Drugs And Changes In Disease
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Author : Jes Olesen
language : en
Publisher:
Release Date : 1974
Cerebral Blood Flow Methods For Measurement Regulation Effects Of Drugs And Changes In Disease written by Jes Olesen and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1974 with Blood categories.