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The Right Ventricle In Adults With Tetralogy Of Fallot


The Right Ventricle In Adults With Tetralogy Of Fallot
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The Right Ventricle In Adults With Tetralogy Of Fallot


The Right Ventricle In Adults With Tetralogy Of Fallot
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Author : Massimo Chessa
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-04-03

The Right Ventricle In Adults With Tetralogy Of Fallot written by Massimo Chessa and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-04-03 with Medical categories.


Tetralogy of Fallot is the most common form of cyanotic congenital heart disease, and one of the first to be successfully repaired by congenital heart surgeons. Although “fixed”, patients born with tetralogy of Fallot cannot be considered “cured”. Improving survival and quality of life for this ever-increasing adult population will continue to challenge the current and future generations of cardiologists. Adult patients with tetralogy of Fallot should be seen by a cardiologist specializing in the care of adults with congenital heart disease, to be monitored for late complications. They need to be checked regularly for any subsequent complications or disturbances of heart rhythm. This monograph is intended as both an introduction to the subject and a timely, comprehensive review, and will be welcomed by adult cardiologists, pediatric cardiologists, internists, surgeons, obstetricians, and intensivists who wish to learn about the most recent discoveries and advances concerning tetralogy of Fallot in adults. It will also be of interest to advanced undergraduates wanting to learn more about the subject.



Congenital Diseases In The Right Heart


Congenital Diseases In The Right Heart
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Author : Andrew N. Redington
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-10-29

Congenital Diseases In The Right Heart written by Andrew N. Redington and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-10-29 with Medical categories.


'Congenital Heart Disease in the Right Heart' is an exhaustive review of the malformations of the right ventricle with particular emphasis on the ability of the ventricle to support circulation and the results of right heart malformations on circulation. Edited by the world’s foremost authorities on the subject, the book benefits from an international team of contributors.



Adult Congenital Heart Disease


Adult Congenital Heart Disease
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Author : Michael A. Gatzoulis
language : en
Publisher: John Wiley & Sons
Release Date : 2008-04-15

Adult Congenital Heart Disease written by Michael A. Gatzoulis and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-04-15 with Medical categories.


Congenital heart disease with its worldwide incidence of 1% is themost common inborn defect. Increasingly, patients are living intoadulthood, with ongoing congenital heart and other medical needs.Sadly, only a small minority have specialist follow-up. However,all patients see their family doctor and may also seek advice fromother health professionals. This practical guide with its straightforward a,b,c approach iswritten for those professionals. Special features of this book: • Introduces the principles of congenital heart diseaseand tells you whom and when to refer for specialist care • Discusses common congenital heart lesions in a practical,easy-to-follow way, with an emphasis on diagnosis and managementissues • Includes an extensive chapter on 'Pregnancy andContraception' (by Philip J. Steer), essential both for familyplanning and for managing safely the pregnant woman with congenitalheart disease • Includes chapters on non-cardiac surgery and lifestyleissues such as work, insurability, travel and driving • Provides invaluable information on dealing with commonemergencies; what to do and what not to do With a wealth of illustrations (including diagrams, EKGs, CXRs,Echos and cardiac MRIs) and with key point tables, this is anessential guide for all health care professionals managing patientswith adult congenital heart disease.



The Right Ventricle In Volume Or Pressure Overload


The Right Ventricle In Volume Or Pressure Overload
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Author : Aleksandra Trzebiatowska-Krzynska
language : en
Publisher: Linköping University Electronic Press
Release Date : 2019-01-07

The Right Ventricle In Volume Or Pressure Overload written by Aleksandra Trzebiatowska-Krzynska and has been published by Linköping University Electronic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-01-07 with categories.


This study is inspired by the gap in knowledge regarding the timing of cardiac surgery and interventions in adult patients with congenital heart disease. There are many parameters used assessing right ventricular function; however, most of them have pitfalls. Understanding the pathomechanisms by which the heart adapts to congenital defects is probably key to find the answer when it is time to intervene and start discussing treatment options. Heart defects are the most frequently occurring congenital disorders. Less than 50% of individuals with moderate to severe congenital heart defects, e.g. transposition of the great arteries (TGA) or tetralogy of Fallot (TOF), survive to adulthood without intervention. Advances in cardiac surgery and better identification of individuals at risk for sudden cardiac death have increased survival rates. Currently, more than 96% of patients with congenital heart disease survive to at least 16 years of age; most undergo corrective surgery but are not cured, and only a few have normal physiology and anatomy. In many cases, the heart must develop mechanisms of adaptation to the changed conditions after surgery. Consequently, correction of the defect creates residual disease with a risk of future complications. To prevent clinical deterioration and to identify the development of complications, patients need lifelong, regular follow up. The choice of followup modalities depends on the cardiac malformation. The right ventricle (RV) plays an important role, as it is often part of the defect or is influenced by the surgery. In the past, research was focused on assessment of left ventricular function (LV), and the RV was “the forgotten ventricle.” Observations and studies in the last few decades brought increased interest into the RV and revealed the importance of the RV in the prognosis of various cardiac diseases. An understanding of RV morphology, pathophysiology and adaptive mechanisms is crucial for further studies of prognosis as well as for research linked to the use of particular diagnostic modalities. When the RV is exposed to increased pressure load, e.g. in atrially corrected transposition of the great arteries (TGA), adaptation affects the cavity volume as well as the wall thickness. When the RV is volume overloaded, adaptation involves enhancement of the RV cavity volume while the wall thickness often remains unchanged under long time. RV ejection fraction (RVEF) gives some information about changes in RV function, but information on myocardial contractility and contractile reserve is also needed. New functional parameters such as strain—also known as myocardial deformation—provide some information about intrinsic myocardial function. In Paper I, we studied functional parameters such as ejection fraction and strain (radial and longitudinal strain for both ventricles) in patients with Tetralogy of Fallot (TOF) and TGA. Longitudinal RV strain was depressed in both patient groups in comparison with that in healthy individuals, and there were additional differences between the two patient groups. In Paper II, we validated three-dimensional echocardiography (3DEcho) against the cardiac magnetic resonance (CMR) gold standard. The study population was limited to patients with TOF. In general, 3DEcho underestimated RV volumes but was able to identify patients with RV dilatation on CMR with high sensitivity. RV longitudinal free wall strain measured by CMR with a cut-off set at -14% identified patients with depressed exercise capacity and low peak oxygen uptake. In Paper III, we studied a new CMR method to quantify and visualise turbulent flow in the heart and vessels. Turbulent flow can be harmful to tissue, blood cells, and endothelium and can contribute to tissue remodeling. In patients with TOF, turbulent flow can be seen as variance in 2DEcho color Doppler. In CMR, increased turbulent kinetic energy (TKE) could be seen with four-dimensional flow. The RV TKE was increased in patients with TOF with pulmonary regurgitation compared with that in healthy controls. In Paper IV, we validated “knowledge-based reconstruction” (KBR), a novel method to calculate RV volume, against CMR in patients with various types of congenital heart defects. Two-dimensional echocardiogram-based threedimensional RV reconstruction is a relatively uncomplicated method that creates a three-dimensional RV model based on a limited number of predefined points of interest (RV structures such as tricuspid annulus, RV free wall, or pulmonary valve). KBR showed good agreement with CMR (intraclass correlation coefficient = 0.84 for RV end-diastolic volume and 0.89 for ejection fraction) but tended to underestimate RV volumes, which is in line with other methods based on ultrasound. Conclusions: 3DEcho is an evolving modality that is able to identify patients with RV dilatation. It can be used clinically for the follow up of patients with congenital heart diseases, especially those with mildly to moderately dilated RVs. When an intervention seems likely, 3DEcho results should be verified by CMR. CMR-derived measurements of longitudinal and radial strain provide a new understanding of RV remodeling and ventricular interdependence in patients with TOF and TGA. Depressed longitudinal strain may indicate a risk of depressed exercise capacity and, in patients with TGA, clinical deterioration. Further studies in larger populations of patients with congenital heart defects are needed, as the altered RV morphology in such patients makes quantitative assessment especially challenging.



Heart Failure In Adult Congenital Heart Disease


Heart Failure In Adult Congenital Heart Disease
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Author : Lorna Swan
language : en
Publisher: Springer
Release Date : 2018-06-27

Heart Failure In Adult Congenital Heart Disease written by Lorna Swan and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-06-27 with Medical categories.


This book sheds new light on the diagnosis and treatment of Heart Failure in adult patients with congenital heart disease. This is a rapidly growing clinical issue for this group of patients and the clinical teams caring for them. The book highlights the major clinical dilemmas in diagnosing heart failure in patients with a lifelong cardiac condition and describes in details the utility of biomarkers, complex imaging and functional tests, e.g. the cardiopulmonary exercise testing. A step-wise approach to treatment is described from drug therapy through to devices and transplantation. As such, the book offers an essential guide for cardiologists and cardiac surgeons looking to optimize the management of patients with delicate physiology and complex disease.



Right Ventricular Physiology Adaptation And Failure In Congenital And Acquired Heart Disease


Right Ventricular Physiology Adaptation And Failure In Congenital And Acquired Heart Disease
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Author : Mark K. Friedberg
language : en
Publisher: Springer
Release Date : 2017-12-19

Right Ventricular Physiology Adaptation And Failure In Congenital And Acquired Heart Disease written by Mark K. Friedberg and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-12-19 with Medical categories.


This book spans topics in both congenital and acquired right heart disease providing readers with detailed information on the physiology, anatomy and myocardial mechanics of the right ventricle (RV), while describing the use of echo and MRI imaging to diagnose, and new developments in surgery and cardiac catheterization to treat. Right Ventricular Physiology, Adaptation and Failure in Congenital and Acquired Heart Disease includes extensive discussion of RV-pulmonary interactions, pulmonary hypertension and ventricular-ventricular interactions, including specific topics in embryology, fetal RV function, RV mechanics, pathophysiology of RV adaptation/ failure, molecular aspects of RV dysfunction, congenital heart disease, pulmonary arterial hypertension, pulmonary valve replacement, stem cell and future therapies.​ It is thus important reading for all cardiovascular medicine professionals, but especially pediatric cardiologists and surgeons, those who manage t hese patients in the cardiac care unit and investigators studying the RV.



The Adult With Tetralogy Of Fallot


The Adult With Tetralogy Of Fallot
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Author : Michael Gatzoulis
language : en
Publisher: Wiley-Blackwell
Release Date : 2001-10-08

The Adult With Tetralogy Of Fallot written by Michael Gatzoulis and has been published by Wiley-Blackwell this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-10-08 with Medical categories.


This monograph on the adult with tetralogy of Fallot (TOF) is the first of a series dedicated to common topics in adult congenital cardiac disease (CHD). Published under the auspices of the International Society of Adult Congenital Cardiac Disease (ISACCD), the monograph provides comprehensive, timely review of the adult with TOF, the most common form of cyanotic CHD. The 6 chapters of the monograph, written by international authorities in the field, contain background information and current data on the major clinical problems facing adults with TOF. Patients born with TOF, although "fixed," are not "cured." Improving survival and quality of life for this ever-increasing adult population will continue to challenge the current and future generations of cardiologists. This monograph is intended as both an introduction to the subject and a timely, comprehensive review, more extensive than a review article and more up-to-date than a textbook. As such, this monograph should be of interest to the internist and the cardiologist who find themselves encountering adults with congenital heart defects with increasing frequency in their practice. Key references provided at the end of each chapter present the relevant literature, allowing for further reading.



Adult Congenital Heart Disease An Issue Of Cardiology Clinics E Book


Adult Congenital Heart Disease An Issue Of Cardiology Clinics E Book
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Author : Karen K Stout
language : en
Publisher: Elsevier Health Sciences
Release Date : 2016-01-07

Adult Congenital Heart Disease An Issue Of Cardiology Clinics E Book written by Karen K Stout and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-01-07 with Medical categories.


The full scope of adult congenital heart disease is examined in this issue of the Cardiology Clinics. Topics include Shunt Lesions, Coarctation of the Aorta, Tetralogy of Fallot, Transposition of Great Arteries, Fontan Repair of Single Ventricle Physiology, Arrhythmias in Adult Congenital Heart Disease, Pulmonary Hypertension. It will also feature special articles on Pregnancy, Non-pharmacologic Treatment, Transition and Psychosocial Issues, and Quality Metrics.



Balancing Your Life With Congenital Heart Disease


Balancing Your Life With Congenital Heart Disease
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Author : Teresa A. Lyle
language : en
Publisher: Pritchett & Hull Associates
Release Date : 2009

Balancing Your Life With Congenital Heart Disease written by Teresa A. Lyle and has been published by Pritchett & Hull Associates this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with categories.




The Right Ventricle In Health And Disease


The Right Ventricle In Health And Disease
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Author : Norbert F. Voelkel
language : en
Publisher: Springer
Release Date : 2014-10-29

The Right Ventricle In Health And Disease written by Norbert F. Voelkel and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-10-29 with Medical categories.


The Right Ventricle in Health and Disease provides a comprehensive and up-to-date database and collection of the available information which describes the structure and function of the normal right ventricle. The right ventricular performance and function reserve has now finally moved to the center of the stage as clinicians recognize that the drugs presently used to treat patients with severe pulmonary hypertension do not necessarily improve the performance of the right ventricle and because the survival depends on the right ventricular function that treatment strategies need to be developed to primarily protect the right ventricle from failing. In-depth chapters discuss right heart function and failure in patients with congenital heart diseases, review modern imaging techniques used to describe right ventricular form and function in patients with right heart failure (including cardiac MRI and PET scanning), describe ventricular interdependence: the left ventricle in pulmonary hypertension and discuss the concept of the sick lung circulation and its contribution to right heart failure. Treatment strategies of chronic right heart failure including drugs and mechanical devices are also discussed.