The Role Of Microtubules In The Biology Of The Oligodendrocyte
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The Role Of Microtubules In The Biology Of The Oligodendrocyte
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Author : Katharine F. Lunn
language : en
Publisher:
Release Date : 1996
The Role Of Microtubules In The Biology Of The Oligodendrocyte written by Katharine F. Lunn and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996 with categories.
The Role Of Microtubules In Cell Biology Neurobiology And Oncology
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Author : Antonio Tito Fojo
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-01-14
The Role Of Microtubules In Cell Biology Neurobiology And Oncology written by Antonio Tito Fojo and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-01-14 with Medical categories.
This book presents the first comprehensive exploration of the dynamic potential of microtubules anti-cancer targets. Written by leading anti-cancer researchers, this groundbreaking volume collects the most current microtubule research available and investigates the potential of microtubules in cancer therapy.
Microrna In Regenerative Medicine
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Author : Chandan K. Sen
language : en
Publisher: Academic Press
Release Date : 2023-05-08
Microrna In Regenerative Medicine written by Chandan K. Sen and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-05-08 with Science categories.
Regulating virtually all biological processes, the genome’s 2,654 newly discovered variants of mature microRNAs – short ribonucleic acid molecules found in eukaryotic cells – hold a key role in the body’s toolkit of regenerative and reparative capacities. Identifying how to activate and deliver these specialist molecules may aid in the repair and regeneration of major tissue and organ damage in future therapies. In MicroRNA and Regenerative Medicine, Second Edition, over 50 leading experts address foundational and emerging topics in the field. Concisely summarizing and evaluating key findings from new research and their translational application, contributors examine current and future significance of clinical research in the miRNA area. Coverage encompasses all major aspects of fundamental stem cell and developmental biology, including the uses of miRNA in cell and tissue plasticity, developmental biology, tissue repair, and regeneration. In particular, contributors provide focused coverage of methodologies for regenerative intervention and tissue engineering. Topics new to this edition include proteomic changes during tissue repair and regeneration, horizontal transfer of miRNAs in tissue regeneration, tissue stemness, peripheral nerve regeneration, miRNA as biomarkers, microRNA in pregnancy and embryo development, exogenous and diet derived microRNA in tissue development, ocular microRNA, mitochondrial microRNA, sensory hair cell death and regeneration, and microRNA in senescence. Features chapter contributions from international leaders in the field, covering the spectrum from bench to bedside Includes short, applied chapters offering focused discussion and practical examples Incorporates multi-color text layout with more than 150 color figures to illustrate important findings
Handbook Of Innovations In Central Nervous System Regenerative Medicine
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Author : António Salgado
language : en
Publisher: Elsevier
Release Date : 2020-06-10
Handbook Of Innovations In Central Nervous System Regenerative Medicine written by António Salgado and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-06-10 with Medical categories.
Handbook of Innovations in CNS Regenerative Medicine provides a comprehensive overview of the CNS regenerative medicine field. The book describes the basic biology and anatomy of the CNS and how injury and disease affect its balance and the limitations of the present therapies used in the clinics. It also introduces recent trends in different fields of CNS regenerative medicine, including cell transplantation, bio and neuro-engineering, molecular/pharmacotherapy therapies and enabling technologies. Finally, the book presents successful cases of translation of basic research to first-in-human trials and the steps needed to follow this path. Areas such as cell transplantation approaches, bio and neuro-engineering, molecular/pharmacotherapy therapies and enabling technologies are key in regenerative medicine are covered in the book, along with regulatory and ethical issues. Describes the basic biology and anatomy of the CNS and how injury and disease affect its balance Discusses the limitations of present therapies used in the clinics Introduces the recent trends in different fields of CNS regenerative medicine, including cell transplantation, bio and neuro-engineering, molecular/pharmacotherapy therapies, and enabling technologies Presents successful cases of translation of basic research to first-in-human trials, along with the steps needed to follow this path
The Biology Of Oligodendrocytes
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Author : Patricia Armati
language : en
Publisher: Cambridge University Press
Release Date : 2010-10-21
The Biology Of Oligodendrocytes written by Patricia Armati and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-10-21 with Medical categories.
Traditionally, oligodendrocytes have been assumed to play a minor supporting role in the central nervous system and their importance has generally been overlooked. For the first time, this book provides a dedicated review of all of the major aspects of oligodendrocyte biology, including development, organization, genetics, and immunobiology. Later chapters emphasize the importance of this underestimated cell to the mammalian central nervous system by exploring the role of myelin synthesis and maintenance in neural disease and repair. Particular attention is paid to multiple sclerosis (MS), arguably the prime example of an acquired demyelinating disease, with detailed examinations of the current concepts regarding demyelination, oligodendroglial damage, and remyelination in MS lesions.
Oligodendrocyte Physiology And Pathology Function
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Author : Markus Kipp
language : en
Publisher:
Release Date : 2021
Oligodendrocyte Physiology And Pathology Function written by Markus Kipp and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021 with categories.
The adult vertebrate central nervous system mainly consists of neurons, astrocytes, microglia cells, and oligodendrocytes. Oligodendrocytes, the myelin-forming cells of the CNS, are subjected to cell stress and subsequent death in a number of metabolic or inflammatory disorders, among which multiple sclerosis (MS) is included. This disease is associated with the development of large demyelinated plaques, oligodendrocyte destruction, and axonal degeneration, paralleled by the activation of astrocytes and microglia as well as the recruitment of peripheral immune cells to the site of tissue injury. Of note, viable oligodendrocytes and an intact myelin sheath are indispensable for neuronal health. For example, it has been shown that oligodendrocytes provide nutritional support to neurons, fast axonal transport depends on proper oligodendrocyte function, and mice deficient in mature myelin proteins eventually display severe neurodegeneration. This Special Issue contains a collection of highly relevant primary research articles as well as review articles focusing on the development, physiology, and pathology of the oligodendrocyte-axon-myelin unit.
Oligodendrocytes
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Author : David A. Lyons
language : en
Publisher: Humana Press
Release Date : 2019-03-01
Oligodendrocytes written by David A. Lyons and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-03-01 with Science categories.
This volume looks at the study of oligodendrocytes through in vitro and in vivo techniques, multiple model organisms, using approaches that bridge scales from molecular through system. Chapters in this book cover topics such as fundamental molecular analyses of oligodendrocytes and myelin; in vitro, ex vivo, and in vivo molecular-cellular-electrophysiology-based techniques; oligodendrocyte formation, homeostasis, and disruption in zebrafish and Xenopus; and parallel system-level imaging of animal and human models. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and thorough, Oligodendrocytes: Methods and Protocols is a valuable reference guide that highlights the expansive and fast-paced nature of research into oligodendrocyte biology underlying health and function.
Molecular Biology Of The Cell
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Author : Bruce Alberts
language : en
Publisher:
Release Date : 2002
Molecular Biology Of The Cell written by Bruce Alberts and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Cytology categories.
Cell Biology And Pathology Of Myelin
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Author : Bernhard H.J. Juurlink
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Cell Biology And Pathology Of Myelin written by Bernhard H.J. Juurlink and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Proceedings of the Fourth International Altschul Symposium held at Saskatoon, Saskatchewan, Canada, June 27-29, 1996
Myelin Basic Protein
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Author : Joan M. Boggs
language : en
Publisher:
Release Date : 2008
Myelin Basic Protein written by Joan M. Boggs and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with Myelin basic protein categories.
The compact myelin sheath formed around nerve axons speeds up nerve conduction and also nurtures the axon. Destruction of this sheath in demyelinating diseases such as multiple sclerosis (MS) results in nerve conduction failure and neurodegeneration. Myelin basic protein (MBP) is the second most abundant protein of central nervous system (CNS) myelin (after the proteolipid protein), representing about 30 % of the total myelin protein and about 10 % of myelin by weight. It is also present in peripheral nervous system (PNS) myelin but as a lower percentage of the total protein. This book addresses the issue of Myelin and the way it binds to negatively-charged lipids on the cytosolic surfaces of the processes and is responsible for adhesion of these surfaces of myelin in the CNS, thus forming the major dense line observed by electron microscopy.