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The Role Of The Hippocampus In Spatial Learning Strategies In Rats


The Role Of The Hippocampus In Spatial Learning Strategies In Rats
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The Role Of The Hippocampus In Spatial Learning Strategies In Rats


The Role Of The Hippocampus In Spatial Learning Strategies In Rats
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Author : Katrina M. Russo
language : en
Publisher:
Release Date : 1989

The Role Of The Hippocampus In Spatial Learning Strategies In Rats written by Katrina M. Russo and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1989 with categories.




Effects Of Bdnf Antagonist Ana 12 On Rats Use Of Spatial Learning Strategies


Effects Of Bdnf Antagonist Ana 12 On Rats Use Of Spatial Learning Strategies
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Author : Lauren M. Buynack
language : en
Publisher:
Release Date : 2020

Effects Of Bdnf Antagonist Ana 12 On Rats Use Of Spatial Learning Strategies written by Lauren M. Buynack and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020 with Electronic dissertations categories.


Prior research has implicated brain-derived neurotropic factor (BDNF) in synaptic plasticity in the hippocampus and in forms of spatial learning and memory that depend on this brain system. Much of this evidence has been indirect, however, and relatively few behavioral studies have directly manipulated BDNF or the receptor that binds it, tropomyosin receptor kinase B (Trk B). The present study examined the role of BDNF in spatial learning by investigating the effects of ANA-12, a noncompetitive antagonist for the Trk B receptor, on spatial learning in a T-maze. Rats received 0.5 or 1.0 mg/kg ANA-12 or saline four hours before training on a T-maze task that could be solved using either a hippocampal-dependent place strategy or a striatum-dependent response strategy. After reaching criterion, the rats received a probe trial in which the two strategies were pitted against one another. Administration of ANA-12 did not impair rats’ ability to learn or perform the T-maze task, but it did cause dose-dependent decreases in their use of place strategies on the probe trial. These results support the idea that BDNF and the Trk B receptor play an important role in spatial learning and memory.



The Hippocampus


The Hippocampus
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Author : Ales Stuchlik
language : en
Publisher: BoD – Books on Demand
Release Date : 2018-07-11

The Hippocampus written by Ales Stuchlik and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-07-11 with Medical categories.


The hippocampus is an important brain region, a true central hub for memory of various kinds and other processes. Neuropsychiatric disorders such as Alzheimer's disease, drug addiction, and schizophrenia are characterized by hippocampal alterations. The dentate gyrus of the hippocampus is a site exhibiting adult neurogenesis. This book covers the topic of the hippocampus from various perspectives. It discusses adult neurogenesis, effect of enriched environments on hippocampal plasticity, and long-term potentiation-associated gene expression. The book also addresses multiscale representations of complex environments and strategies in the hippocampus-dependent spatial tasks. Finally, insight into the hippocampus as a link between negative affect and relapse to psychostimulants is provided. The book collects evidence of various hippocampal functions in healthy and disordered brain.



Spatial Learning And Navigation In Neuro Mimetic Systems


Spatial Learning And Navigation In Neuro Mimetic Systems
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Author : Angelo Arleo
language : en
Publisher:
Release Date : 2000

Spatial Learning And Navigation In Neuro Mimetic Systems written by Angelo Arleo and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000 with Rats categories.




The Role Of Hippocampal Place Cells In The Development Of Spatial Learning In The Rat


The Role Of Hippocampal Place Cells In The Development Of Spatial Learning In The Rat
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Author : Trent C. Holmberg
language : en
Publisher:
Release Date : 1994

The Role Of Hippocampal Place Cells In The Development Of Spatial Learning In The Rat written by Trent C. Holmberg and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994 with Hippocampus (Brain) categories.




Hippocampal Place Fields


Hippocampal Place Fields
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Author : Sheri J.Y. Mizumori
language : en
Publisher: Oxford University Press
Release Date : 2008-02-26

Hippocampal Place Fields written by Sheri J.Y. Mizumori and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-26 with Medical categories.


Data from neuropsychological and animal research suggest that the hippocampus plays a pivotal role in two relatively different areas: active navigation, as well as episodic learning and memory. Recent studies have attempted to bridge these disparate accounts of hippocampal function by emphasizing the role that hippocampal place cells may play in processing the spatial contextual information that defines situations in which learned behaviors occur. A number of established laboratories are currently offering complementary interpretations of place fields, and this book will present the first common platform for them. Bringing together research from behavioral, genetic, physiological, computational, and neural-systems perspectives will provide a thorough understanding of the extent to which studying place-field properties has informed our understanding of the neural mechanisms of hippocampus-dependent memory. Hippocampal Place Fields: Relevance to Learning and Memory will serve as a valuable reference for everyone interested in hippocampal function.



Animal Spatial Cognition


Animal Spatial Cognition
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Author : Catherine Thinus-Blanc
language : en
Publisher: World Scientific
Release Date : 1996

Animal Spatial Cognition written by Catherine Thinus-Blanc and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996 with Science categories.


The ?Cognitive Map? (Tolman, 1948) is a key notion in spatial processing studies. It refers to high level spatial representations. Although widely used, this term remains ambiguous. The aim of this book is two-fold: (1) to examine the most noteworthy studies (in laboratory settings) which have contributed during the last five decades to a better understanding of animal spatial representations; (2) to provide some hints for future research.Spatial tests designed by psychologists are useful tools for understanding the brain substrates of spatial memory. Conversely, brain treatments allow us to analyse the complex psychological mechanisms underlying spatial orientation. Within this interdisciplinary context, it is extremely important to take stock of a notion used (and sometimes misused) in cognitive neurosciences.



The Effects Of Impaired Hippocampal Glial Function On Spatial Learning In Rats


The Effects Of Impaired Hippocampal Glial Function On Spatial Learning In Rats
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Author : Kate Adams
language : en
Publisher:
Release Date : 2004

The Effects Of Impaired Hippocampal Glial Function On Spatial Learning In Rats written by Kate Adams and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Cognition in animals categories.




Structural Correlates Of Spatial Learning In The Hippocampus Of Adult Rats


Structural Correlates Of Spatial Learning In The Hippocampus Of Adult Rats
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Author : May-Britt Moser
language : en
Publisher:
Release Date : 1995

Structural Correlates Of Spatial Learning In The Hippocampus Of Adult Rats written by May-Britt Moser and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995 with categories.




The Hippocampal And Parietal Foundations Of Spatial Cognition


The Hippocampal And Parietal Foundations Of Spatial Cognition
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Author : Neil Burgess
language : en
Publisher: Oxford University Press, USA
Release Date : 1999

The Hippocampal And Parietal Foundations Of Spatial Cognition written by Neil Burgess and has been published by Oxford University Press, USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with Medical categories.


As we move around in our environment, and interact with it, many of the most important problems we face involve the processing of spatial information. We have to be able to navigate by perceiving and remembering the locations and orientations of the objects around us relative to ourself; we have to sense and act upon these objects; and we need to move through space to position ourselves in favourable locations or to avoid dangerous ones. While this appears so simple that we don't even think about it, the difficulty of solving these problems has been shown in the repeated failure of artificial systems to perform these kinds of tasks efficiently. In contrast, humans and other animals routinely overcome these problems every single day. This book examines some of the neural substrates and mechanisms that support these remarkable abilities. The hippocampus and the parietal cortex have been implicated in various core spatial behaviours, such as the ability to localise an object and navigate to it. Damage to these areas in humans and animals leads to impairment of these spatial functions. This collection of papers, written by internationally recognized experts in the field, reviews the evidence that each area is involved in spatial cognition, examines the mechanisms underlying the generation of spatial behaviours, and considers the relative roles of the parietal and hippocampal areas, including how each interacts with the other. The papers integrate a wide range of theoretical and experimental approaches, and touch on broader issues relating to memory and imagery. As such, this book represents the state of the art of current research into the neural basis of spatial cognition. It should be of interest to anyone - researchers or graduate students - working in the areas of cognitive neuroscience, neuroanatomy, neuropsychology, and cognition generally.