The Separation Of Enantiomers By Capillary Electrophoresis
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The Separation Of Enantiomers By Capillary Electrophoresis
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Author : Stephen Wren
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-04-17
The Separation Of Enantiomers By Capillary Electrophoresis written by Stephen Wren and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-04-17 with Technology & Engineering categories.
This book gives a comprehensive overview on the principles of physical and mathematical modelling of enantiomer separation by CE. Method development strategies are shown and cyclodextrins as a popular group of chiral selectors as well as some other selectors used as buffer additives for enantiomer separation in free solution are described.
Separation Of Enantiomers In Capillary Electrophoresis
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Author : Thomas Schmitt
language : en
Publisher:
Release Date : 1995
Separation Of Enantiomers In Capillary Electrophoresis written by Thomas Schmitt and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995 with Capillary electrophoresis categories.
Chiral Separations By Capillary Electrophoresis
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Author : Ann Van Eeckhaut
language : en
Publisher: CRC Press
Release Date : 2009-11-11
Chiral Separations By Capillary Electrophoresis written by Ann Van Eeckhaut and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-11-11 with Medical categories.
Covers the Fundamentals of Chiral Separation, Available Chiral Selectors, and Numerous Applications of Chiral Separation by Capillary ElectrophoresisSince the 1980s, modern analytical tools have enabled capillary electrophoresis to become a standard part of the chemist's toolkit. With contributions from international experts, Chiral Separations by
Chiral Separations
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Author : Gerald Gübitz
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-02-02
Chiral Separations written by Gerald Gübitz and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-02 with Science categories.
Prominent experts from around the world detail the chromatographic and electroseparation techniques they have developed for chiral separations on an analytical scale. Described in step-by-step detail to ensure successful experimental results, the procedures are presented as either general methods or as specific applications to substance classes and special compounds, with emphasis on high performance liquid chromatography and capillary electrophoresis techniques, but also including thin layer chromotographic, gas chromatographic, supercritical fluid chromatographic as well as recent electrochromotographic techniques.
Chiral Recognition In Separation Methods
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Author : Alain Berthod
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-06-16
Chiral Recognition In Separation Methods written by Alain Berthod and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-06-16 with Science categories.
What drives a scientist to edit a book on a speci c scienti c subject such as chiral mechanisms in separation methods? Until December 2005, the journal Analytical Chemistry of the American Chemical Society (Washington, DC) had an A-page section that was dedicated to simple and clear presentations of the most recent te- niques or the state of the art in a particular eld or topic. The “A-page” section was prepared for a broad audience of chemists including industrial professionals, s- dents as well as academics looking for information outside their eld of expertise. 1 Daniel W. Armstrong, one of the editors of this journal and a twenty-year+ long friend, invited me to present my view on chiral recognition mechanisms in a simple and clear way in an “A-page” article. In 2006, the “A-page” section was maintained as the rst articles at the beginning of each rst bi-monthly issue but the pagination was no longer page distinguished from the regular research articles published by the journal. During the time between the invitation and the submission, the A-page section was integrated into the rest of the journal and the article appeared as (2006) Anal Chem (78):2093–2099.
Capillary Electrophoresis Separation Of Neutral Organic Compounds Pharmaceutical Drugs Enantiomers And Anions
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Author : Qing Feng
language : en
Publisher:
Release Date : 2011
Capillary Electrophoresis Separation Of Neutral Organic Compounds Pharmaceutical Drugs Enantiomers And Anions written by Qing Feng and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with categories.
The focus of this thesis is on using capillary electrophoresis (CE) with on-column UV detection in achiral and chiral separations. Chapter 1 provides a brief introduction to the principle, mechanism, meaning and application of the CE method. Chapter 2 presents the CE separation of multivalent anions by using di- and tetracationic ion pairing reagents. Two newly developed UV transparent phosphonium-based cationic reagents were evaluated as additives to the background electrolyte of CE for the separation of multiply charged anions, including several complex anions. These cationic reagents showed moderate suppression of the electroosmotic flow (EOF), interacted with the analytes to improve their separation and often improved the peak shape. The effects of the additives and their concentration on the separation were studied, as well as the buffer type, pH and voltage. Chapter 3 examines the CE enantiomeric separation of sixteen 4,5-disubstituted imidazoles. Different cyclodextrin-based chiral selectors were used and the separation conditions were optimized. Meanwhile, comparisons of these results to HPLC separations were made.
Capillary Electrophoresis
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Author : Patrick Camilleri
language : en
Publisher: CRC Press
Release Date : 1997-11-25
Capillary Electrophoresis written by Patrick Camilleri and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997-11-25 with Medical categories.
The importance of capillary electrophoresis (CE) as an analytical tool has increased dramatically over the last ten years. It has changed from being an exploratory technique, mainly of academic interest, to one that is applied to solve "real" analytical problems. CE is easily adapted to its various modes of operation, often requiring little more than a change of the buffer solution, and is quickly becoming the preferred technique when analyzing minute amounts of available material. Featuring new chapters on CE analysis of inorganic ions and carbohydrates, the new edition of Capillary Electrophoresis not only presents this method as an academic tool, but also provides applications for solving "real-world" analytical problems. This updated Second Edition reflects the increasing use of CE over the last 10 years, how it is being applied, and the basic theoretical aspects of the separation and detection methodology of CE. Capillary Electrophoresis: Theory and Practice will appeal to students and professionals of analytical chemistry, physical chemistry, biochemistry, and biotechnology and includes suitable experiments designed to be attempted by university or college students, or anyone else wishing to familiarize themselves with CE.
Enantiomeric Separation Of Chiral Drugs By Using Capillary Electrophoresis Chromatography With Chiral Selectors
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Author : Sujin Ahn
language : en
Publisher:
Release Date : 2005
Enantiomeric Separation Of Chiral Drugs By Using Capillary Electrophoresis Chromatography With Chiral Selectors written by Sujin Ahn and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with Enantiomers categories.
Chiral Separation Methods For Pharmaceutical And Biotechnological Products
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Author : Satinder Ahuja
language : en
Publisher: John Wiley & Sons
Release Date : 2011-03-31
Chiral Separation Methods For Pharmaceutical And Biotechnological Products written by Satinder Ahuja and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-03-31 with Science categories.
Discusses chiral separations and offers guidance for selecting the optimum method for desired results Chiral separations represent the most intriguing and, by some measures, most difficultseparations of chemical compounds. This book provides researchers and students an under-standing of chiral separations and offers a convenient route to selecting the best separation method, saving considerable time and cost in product development. Considering chiral separations in the biotechnological and pharmaceutical industries, as well as for food applications, Dr. Ahuja provides insights into a broad range of topics. Opening with a broad overview of chiral separations, regulatory considerations in drug product development, and basic issues in method development, the book: Covers a variety of modern methods such as gas chromatography, high performance liquid chromatography, supercritical fluid chromatography, and capillary electrophoresis Deals with the impact of chirality on the biological activity of small and large molecules Provides detailed information on useful chiral stationary phases (CSPs) for HPLC Includes handy information on selection of an appropriate CSP, including mechanistic studies Offers strategies for fast method development with HPLC, SFC, and CE Discusses preparatory methods utilized in the pharmaceutical industry With in-depth discussions of the current state of the field as well as suggestions to assist future developments, Chiral Separation Methods for Pharmaceutical and Biotechnological Products is an essential text for laboratory investigators, managers, and regulators who are involved in chiral separations in the pharmaceutical industry, as well as students preparing for careers in these fields.
Chromatographic Enantioseparation
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Author : Stig G. Allenmark
language : en
Publisher: Ellis Horwood
Release Date : 1988
Chromatographic Enantioseparation written by Stig G. Allenmark and has been published by Ellis Horwood this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988 with Science categories.
Allenmark (microbiological chemistry, U. of Gothenburg) gives a thorough treatment of chiral chromatography, covering basic theory, methods (particularly stationary phase design), and applications. Treatment is self-contatined; early chapters explain principles, incorporating background material on organic stereochemistry; later ones cover instrumentation, preparation, synthesis, and analysis. Includes in-depth coverage of liquid chromatographic methods and discussion of industrial uses for large-scale preparative resolutions, including column sample capacity, chromatographic reproducability, and automatic operation. Acidic paper. Annotation copyrighted by Book News, Inc., Portland, OR