[PDF] The Skin And Gene Therapy - eBooks Review

The Skin And Gene Therapy


The Skin And Gene Therapy
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The Skin And Gene Therapy


The Skin And Gene Therapy
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Author : Ulrich R. Hengge
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

The Skin And Gene Therapy written by Ulrich R. Hengge and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


This first comprehensive guide to the novel field of gene therapy in the skin provides insight into the basic principles and methods of gene transfer into the skin and its applications. It enables the understanding of possibilities and implications such as immunization and treatment as well as safety aspects. Gene therapy in dermatology is the avantgarde of a new field in science with a great future for human health.



Gene Technology And Gene Therapy In Dermatology


Gene Technology And Gene Therapy In Dermatology
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Author : Ulrich R. Hengge
language : en
Publisher: S. Karger AG (Switzerland)
Release Date : 2002-01-01

Gene Technology And Gene Therapy In Dermatology written by Ulrich R. Hengge and has been published by S. Karger AG (Switzerland) this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-01-01 with Medical categories.


Basic concepts and recent advances in the field In recent years the skin has become an important target organ of gene technology and gene therapy. Its easy accessibility, well-established culture conditions and grafting techniques, as well as its function as an immune organ make it a promising candidate for the development of innovative treatment strategies. This special issue of Cells Tissues Organs gives an overview of the latest achievements in the field of skin gene therapy focusing on basic research and initial preclinical applications. It describes novel techniques of generating epidermal equivalents from hair follicle cells, the reaction of keratinocytes to exogenous DNA, and the genetic engineering of skin to be used as a bioreactor or a metabolic sink' in the treatment of metabolic disorders. Further potential applications of skin gene therapy include the treatment of chronic wounds, hypertrophic scars, keloids, and cancer, as well as its role in soft tissue reconstruction. Since gene therapy is a truly interdisciplinary field, this publication is recommended reading not only for dermatologists, geneticists, bioengineers, cell biologists and immunologists, but also for clinicians with an interest in cancer, metabolic diseases, skin biology and tissue engineering.



First International Symposium On Gene Technology And Skin Gene Therapy


First International Symposium On Gene Technology And Skin Gene Therapy
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Author : International Symposium on Gene Technology and Skin Gene Therapy. 1, 2000, Essen
language : en
Publisher:
Release Date : 2000

First International Symposium On Gene Technology And Skin Gene Therapy written by International Symposium on Gene Technology and Skin Gene Therapy. 1, 2000, Essen and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000 with categories.




Gene Therapy In Reconstructive And Regenerative Surgery


Gene Therapy In Reconstructive And Regenerative Surgery
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Author : Giorgio Giatsidis
language : en
Publisher: Springer
Release Date : 2018-08-02

Gene Therapy In Reconstructive And Regenerative Surgery written by Giorgio Giatsidis and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-08-02 with Medical categories.


This book offers an updated overview of the most recent research advances in the field, a comparison of established techniques and methods, a discussion on current experimental and translational challenges, and a commentary on potential opportunities and future directions. Dedicated chapters address and review the preclinical and clinical state-of-the-art of gene therapies for the reconstructive and regenerative surgery of skin and wounds, pathological scars, cartilage, tendons, skeletal muscles, and bio-engineered flaps. A brief guide to developing gene therapy clinical trials in the context of reconstructive and regenerative surgery is also provided. Biomedical and technological innovations are transforming our capacity to use gene therapies to safely and effectively repair, reconstruct, and regenerate tissues that are deficient or have been damaged by trauma and diseases. The targeted and controlled modulation of gene expression in tissues represents a game-changing, next-generation therapeutic tool for the modern reconstructive surgeon, expanding the horizon of regenerative surgery and tissue engineering. Through gene therapies, surgeons can direct (stem) cell differentiation and cell function, modulate the release of growth/transcriptional factors, affect the biological properties of regenerative scaffolds, control tissue inflammation, or induce immune-suppression in composite tissue allotransplants and xenotransplants. Written by renowned reconstructive surgeons and leading experts in each of these fields - from top academic institutions around the globe, the book provides an initial practical guide for veteran and newcomer surgeons alike, as well as for researchers interested in exploring the latest gene-based therapeutic strategies for reconstructive and regenerative surgery.



Molecular Biology Of The Skin


Molecular Biology Of The Skin
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Author : Michael Darmon
language : en
Publisher: Academic Press
Release Date : 2012-12-02

Molecular Biology Of The Skin written by Michael Darmon and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Science categories.


Molecular Biology of the Skin: The Keratinocyte comprehensively reviews the major aspects of keratinocyte and epidermal differentiation, physiology, and pathology, primarily focusing on the molecular aspects. This exciting new resource discusses keratin genes, retinoic acid, and the use of transgenic animals in the study of dermatological pathology. The volume also highlights areas of genetic disease, new animal models to help in understanding dermatological disorders, and gene therapy using skin as a target. W.W. Franke, a pioneer in the study of the molecular biology of keratins, has written the foreword for the book. Molecular Biology of the Skin: The Keratinocyte is intended for use by dermatologists and basic researchers in cell and developmental biology. It will also be valuable for surgeons and other clinicians as well as researchers in gene therapy, virology, and pharmacology. * * Reviews keratinocyte (and epidermal) differentiation. physiology, and pathology, focusing on the molecular aspects * -Discusses keratin genes, retinoic acid, and the use of transgenic animals in the study of dermatalogical pathology * -Highlights genetic disease, new animal models, and gene therapy



Skin Fibroblast Mediated Gene Therapy


Skin Fibroblast Mediated Gene Therapy
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Author : Theodore D. Palmer
language : en
Publisher:
Release Date : 1990

Skin Fibroblast Mediated Gene Therapy written by Theodore D. Palmer and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1990 with categories.




Progress In Gene Technology And Skin Gene Therapy


Progress In Gene Technology And Skin Gene Therapy
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Author : Ulrich R. Hengge
language : en
Publisher: S Karger Ag
Release Date : 2004

Progress In Gene Technology And Skin Gene Therapy written by Ulrich R. Hengge and has been published by S Karger Ag this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Science categories.


Significant progress has been made in gene technology and skin gene therapy in the last few years. Besides the development of suitable animal models, novel molecular technologies such as small inhibitory RNA are discussed, which enable the modification of sequence-specific gene expression. Progress is reported in the field of DNA vaccination against HIV-1 as well as in the correction of xeroderma pigmentosum using retroviral-based gene transfer. In addition to gene technology and skin gene therapy, recent advances in molecular diagnostics of malignancy are described. Microarray-based gene expression profiling is a powerful technology with which up to 22,000 genes can simultaneously be analyzed in a given tissue. It is used today by several groups to characterize malignant melanoma and other tumors on a molecular level, identifying important dysregulated pathways and gene products and comparing them with those of normal human melanocytes and benign nevi. Providing an overview of the latest techniques and achievements in the field, this publication is recommended to dermatologists, geneticists, bioengineers, cell biologists and immunologists, and anyone interested in learning more about new molecular approaches in biomedicine.



Genetic Skin Disorders


Genetic Skin Disorders
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Author : Virginia P. Sybert
language : en
Publisher: Oxford University Press
Release Date : 2017-01-02

Genetic Skin Disorders written by Virginia P. Sybert and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-01-02 with Medical categories.


This fully revised and updated edition of GENETIC SKIN DISORDERS reflects the most current understanding of the diagnosis, treatment, genetic basis, and differential diagnoses of inherited skin disorders. Organized with the needs of busy clinicians in mind, it offers detailed clinical guidance on the signs, symptoms, mode of inheritance, recurrence risk, and diagnosis of over 300 skin disorders, all in an accessible, at-a-glance format. Annotated bibliographies highlight the most relevant and up-to-date medical literature. Newly compiled lists of support groups, both national and international, for patients and their families supplement the ample resources for medical professionals. Informed by the author's extensive clinical experience and suffused with a distinctive, witty voice, GENETIC SKIN DISORDERS is an ideal companion in the laboratory, clinic, or consulting room. FEATURES · Includes both disease-based chapters and an appendix of skin signs that simplifies differential diagnosis for specialists and general practitioners alike · More than 800 color photographs illustrate the full spectrum of hair, skin, and nail abnormalities · Updated to reflect current classification of inherited skin disorders and the molecular underpinnings of these conditions



Antisense Gene Therapy For The Skin


Antisense Gene Therapy For The Skin
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Author : Andrew Colin Gray
language : en
Publisher:
Release Date : 1999

Antisense Gene Therapy For The Skin written by Andrew Colin Gray and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with Gene therapy categories.




Gene Therapy


Gene Therapy
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Author : Kenneth W. Culver
language : en
Publisher: Mary Ann Liebert
Release Date : 1994

Gene Therapy written by Kenneth W. Culver and has been published by Mary Ann Liebert this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994 with Medical categories.