Trail Fas Ligand Tnf And Tlr3 In Cancer
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Trail Fas Ligand Tnf And Tlr3 In Cancer
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Author : Olivier Micheau
language : en
Publisher: Springer
Release Date : 2017-07-03
Trail Fas Ligand Tnf And Tlr3 In Cancer written by Olivier Micheau and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-07-03 with Medical categories.
This volume provides the current understanding of death receptor's/TLR3 signaling regulation in cancer. Death receptors, including TRAIL-R1, TRAIL-R2, Fas and TNF-RI, owing to their ability to trigger apoptosis and to contribute to the elimination of cancer cells by the immune system have been considered, to variable extent, as important therapeutic targets for cancer therapy. But an increasing body of evidence suggests that some of these receptors may also contribute to tumorigenesis, or that new players such as TLR3 may be targeted for cancer therapy due to their ability to behave like death receptors.
Tnfr Superfamily Oligomerization And Signaling
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Author : Cristian Roberto Smulski
language : en
Publisher: Frontiers Media SA
Release Date : 2021-06-08
Tnfr Superfamily Oligomerization And Signaling written by Cristian Roberto Smulski and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-06-08 with Science categories.
Cell Death Regulation In Health And Disease Part A
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Author :
language : en
Publisher: Academic Press
Release Date : 2020-04-02
Cell Death Regulation In Health And Disease Part A written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-04-02 with Science categories.
Cell Death Regulation in Health and Disease - Part A, Volume 351, the latest release in the International Review of Cell and Molecular Biology reviews current advances in cell and molecular biology. The series publishes timely topics authored by prominent cell and molecular biologists. This release is part of a 3-part series which comprises a comprehensive view of cell death regulation in a variety of biological contexts. Chapters cover Membrane dynamics in cell death regulation, The role of necroptosis in intestinal dysfunction, Regulation of cell death in the cardiovascular system, Cell death in bacterial and viral infection, and much more. Provides a comprehensive collection of front-of-the line research in the field of cell death regulation Authored by established and active cell and molecular biologists and drawn from international sources Includes invited review articles that cover selected topics in multiple organisms and disease settings
Tumor Suppressor Par 4
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Author : Vivek M. Rangnekar
language : en
Publisher: Springer Nature
Release Date : 2022-01-08
Tumor Suppressor Par 4 written by Vivek M. Rangnekar and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-08 with Medical categories.
Par-4 is a tumor suppressor protein first discovered and identified in 1993 by Dr. Vivek Rangnekar’s laboratory in prostate cancer cells undergoing apoptosis. Par-4 (later also known as PAWR) is a naturally occurring tumor suppressor. Studies have indicated that Par-4 selectively induces apoptosis in cancer cells while leaving normal, healthy, cells unaffected. Mechanisms contributing to the cancer-selective action of Par-4 have been associated with protein kinase A activation of intracellular Par-4 in cancer cells or GRP78 expression primarily on the surface of cancer cells. Par-4 is downregulated, inactivated or mutated in diverse cancers. This first of two volumes will be the first on the market on the topic of Par-4, and will provide the opportunity for researchers to discuss the future direction of studies, broaden the scope of research, and contribute a more complete understanding of the molecule’s structural features, key functional domains, regulation and relevant basic and clinical/translational facets.
Oncogene And Cancer
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Author : Yahwardiah Siregar
language : en
Publisher: Inst za onkologiju i radiol
Release Date : 2013-01-24
Oncogene And Cancer written by Yahwardiah Siregar and has been published by Inst za onkologiju i radiol this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-01-24 with Medical categories.
This book describes a course of cancer growth starting from normal cells to cancerous form and the genomic instability, the cancer treatment as well as its prevention in form of the invention of a vaccine. Some diseases are also discussed in detail, such as breast cancer, leucaemia, cervical cancer, and glioma. Understanding cancer through its molecular mechanism is needed to reduce the cancer incidence. How to treat cancer more effectively and the problems like drug resistance and metastasis are very clearly illustrated in this publication as well as some research result that could be used to treat the cancer patients in the very near future. The book was divided into six main sections: 1. HER2 Carcinogenesis: Etiology, Treatment and Prevention; 2. DNA Repair Mechanism and Cancer; 3. New Approach to Cancer Mechanism; 4. New Role of Oncogenes and Tumor Suppressor Genes; 5. Non Coding RNA and Micro RNA in Tumorigenesis; 6. Oncogenes for Transcription Factors
Engineered Immune Cells In Cancer Immunotherapy Eicci
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Author : Cristina Maccalli
language : en
Publisher: Frontiers Media SA
Release Date : 2023-02-28
Engineered Immune Cells In Cancer Immunotherapy Eicci written by Cristina Maccalli and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-02-28 with Medical categories.
Holland Frei Cancer Medicine 8
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Author : James F. Holland
language : en
Publisher: PMPH-USA
Release Date : 2010
Holland Frei Cancer Medicine 8 written by James F. Holland and has been published by PMPH-USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010 with Medical categories.
Holland Frei Cancer Medicine serves as a quick reference to current information on an extensive list of cancers, including breast, lung, thyroid, colorectal, ovarian, prostate, and gastric cancer, to name but a few. Presented as an accessible pocket-sized handbook, the chapters are organized in an outline format, offering only the most essential information on the etiology, staging (including TNM staging) and treatment for each cancer type. Individual chapters are devoted to the molecular biology of cancer, cancer prevention, cancer screening, the mechanisms of chemotherapy, and diagnostic imaging in cancer. Additionally, each chapter lists all the major phase III clinical trials, and therefore, serves as an excellent reference of the major randomized controlled trials for each cancer reported to date. Specific chapters are also dedicated to the discussion of oncologic emergencies, pain and palliation, and prescription complications. At the conclusion of the book, a glossary of oncologic terms and chemotherapeutic drug programs, a table of common cancer incidences, and an overview of the mechanisms, common uses, and related toxicities of various anti-cancer agents are featured. In addition, performance status tables, mathematical formulas and a listing of common biomedical / cancer web sites are highlighted.
Necrotic Cell Death
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Author : Han-Ming Shen
language : en
Publisher: Springer Science & Business Media
Release Date : 2014-03-29
Necrotic Cell Death written by Han-Ming Shen and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-03-29 with Science categories.
Starting with discussion of basic concepts and the molecular mechanisms of necrosis, this book looks first at several forms of necrotic cell death that have been identified, including necroptosis, autophagic cell death, and PARP-mediated cell death. As necrotic cell death is increasingly known to play a critical role in many physiological processes, the next chapters discuss its effect on metabolism, inflammation, immunity, and development. Necrotic cell death is closely implicated in human diseases like cancer, so the next chapters examine its relevance to human diseases, and final chapters cover methodologies for measuring necrosis. This book presents comprehensive coverage of necrosis from recognized experts from leading academic and medical institutions around the world. In contrast to apoptosis, well-defined as a form of programmed cell death, necrosis used to be considered as accidental (i.e., non-programmed) cell death, usually in response to a severe injury. Accumulating evidence now suggests, however, that necrosis is also programmed and controlled by distinctive "death machinery" in response to various stimuli like oxidative stress or DNA damage.
Oncoimmunology
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Author : Laurence Zitvogel
language : en
Publisher: Springer
Release Date : 2017-12-13
Oncoimmunology written by Laurence Zitvogel and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-12-13 with Medical categories.
In this book, leading experts in cancer immunotherapy join forces to provide a comprehensive guide that sets out the main principles of oncoimmunology and examines the latest advances and their implications for clinical practice, focusing in particular on drugs with FDA/EMA approvals and breakthrough status. The aim is to deliver a landmark educational tool that will serve as the definitive reference for MD and PhD students while also meeting the needs of established researchers and healthcare professionals. Immunotherapy-based approaches are now inducing long-lasting clinical responses across multiple histological types of neoplasia, in previously difficult-to-treat metastatic cancers. The future challenges for oncologists are to understand and exploit the cellular and molecular components of complex immune networks, to optimize combinatorial regimens, to avoid immune-related side effects, and to plan immunomonitoring studies for biomarker discovery. The editors hope that this book will guide future and established health professionals toward the effective application of cancer immunology and immunotherapy and contribute significantly to further progress in the field.
Index Medicus
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Author :
language : en
Publisher:
Release Date : 2004
Index Medicus written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Medicine categories.
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.