Traumj Ger
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Extrudable Gel Forming Bioabsorbable Hemostatic Tissue Adhesives For Traumatic And Burn Wounds
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Author : Shalaby W. Shalaby
language : en
Publisher:
Release Date : 1996
Extrudable Gel Forming Bioabsorbable Hemostatic Tissue Adhesives For Traumatic And Burn Wounds written by Shalaby W. Shalaby and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996 with categories.
Two of the three segments of the planned studies, adhesive skin wound augmentation (ASWA) and burn wound healing (BWH) are underway. Plans for the third segment, hemostasis, have been finalized. The studies on ASWA are practically complete and they include: (1) polymer synthesis and characterization of primary gel-formers; (2) preparation and evaluation of candidate formulations; and (3) conducting the animal studies and completing data analysis. Studies on BWH are in progress and they include (1) preparation and evaluation of candidate formulations, and (2) initiation of the animal studies. Results of the study on the effect of gel-forming formulations on skin wounds indicate that (1) using gel-formulations without antibiotics can lead to improved wound healing and increase in wound strength regain with partial reliance on mechanical stapling, and (2) high concentrations of the antibiotic vancomycin compromises the wound healing.
A Biomimetic Reverse Thermal Gel For Spinal Cord Injury
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Author : James Bardill
language : en
Publisher:
Release Date : 2015
A Biomimetic Reverse Thermal Gel For Spinal Cord Injury written by James Bardill and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015 with Drug delivery systems categories.
Menthol Gel For The Management Of Neuropathic Pain After Hand Surgery
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Author :
language : en
Publisher:
Release Date : 2017
Menthol Gel For The Management Of Neuropathic Pain After Hand Surgery written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017 with categories.
Menthol gel for the management of neuropathic pain after hand surgery u2013 a case reportKokki Hannu, Kokki MerjaSchool of Medicine, University of Eastern Finland, Kuopio, Finland; Department of Anaesthesia and Operative Services, Kuopio University Hospital, Kuopio, FinlandBackgroundThe prevalence of neuropathic pain varies between 1.3% and 18% depending of the definition. It affects significantly the quality of life and has important social and economic consequences (1). Complex regional pain syndrome (CRPS) is one of the most severe neuropathic pain conditions. Up to 26% of patients with surgical treatment of traumatic hand injuries may develop CRPS (2).Menthol has been used for analgesia since the ancient times. Recent interest on menthol in pain management has risen since 2002 when the menthol sensing channel transient receptor potential melastatin 8 (TRPM8) was identified (3,4). Since then menthol has been shown to be effective on the management of several acute nociceptive, inflammatory and neuropathic pain conditions.Here we present a case report where menthol was used in the treatment of refractory CRPS after traumatic hand injury and surgery.CaseA 39 years old non-smoking healthy male had a traumatic complete tear of the distal biceps tendon on 18th of June 2017. Two days later a surgery was performed to reattach the tendon to the bone. After surgery he developed a severe lancinating neuropathic pain at the elbow area. Pain was worse on night-time, NRS 7-8/10 and he could sleep only 3-4 h a night. Paracetamol-codeine and titzanidine were uneffective, gabapentin had some effect, but he was so somnolent at daytima that he could not return to work. Four weeks after the primary injury he was prescribed menthol-gel (Ice Poweru00ae, Fysioline Ltd., Tampere, Finland) for day-time used and menthol patches for nights on the elbow area. Since the first night, he was able to sleep 6-7 h a night and pain rating decreased to 3-5/10. After 4 weeks of treatment, he returned to work and was able to stop the menthol-use. Six months after the injury the muscle function has restored, he may have some muscle aches in few nights a week, which are relieved with menthol gel. At daytimes, he has no pain nor other symptoms.Discussion and conclusionsMenthol is a counter-irritant compound. Initially it stimulates nociceptors and then desensitize them. TRPM8 channels are expressed widely in pain system. In periphery 15% of sensory neurons are TRPM8 activated by menthol. Topically applied menthol activates higher central analgesic pathways also. TRPM8 receptors are expressed in the dorsal root ganglia and the trigeminal ganglia, and in spinal cord in the dorsal and ventral root, i.e. in the ascending and descending pain system (5).CRPS is a relatively common outcome after surgery and trauma and often treatment-resistant. This case report shows that topical menthol could be highly potent component in multimodal pain management in persistent post-operative/post-traumatic pain.References1. Inoue S, Taguchi T, Yamashita T, Nakamura M, Ushida T. The prevalence and impact of chronic neuropathic pain on daily and social life: A nationwide study in a Japanese population. Eur J Pain. 2017;21:727-37.2. Savau015f S, u0130nal EE, Yavuz DD, Uslusoy F, Altuntau015f SH, Aydu0131n MA. Risk factors for complex regional pain syndrome in patients with surgically treated traumatic injuries attending hand therapy. J Hand Ther. 2018;31:250-254.3. McKemy DD, Neuhausser WM, Julius D. Identification of a cold receptor reveals a general role for TRP channels in thermosensation. Nature. 2002;416:52-8.4. Peier AM, Moqrich A, Hergarden AC, Reeve AJ, Andersson DA, Story GM, Earley TJ, Dragoni I, McIntyre P, Bevan S, Patapoutian A. A TRP channel that senses cold stimuli and menthol. Cell. 2002;108:705-15.5. Facer P, Casula MA, Smith GD, Benham CD, Chessell IP, Bountra C, Sinisi M, Birch R, Anand P. Differential expression of the capsaicin receptor TRPV1 and related novel receptors TRPV3, TRPV4 and TRPM8 in normal human tissues and changes in traumatic and diabetic neuropathy. BMC Neurol. 2007 May 23;7:11.
Trauma
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Author :
language : en
Publisher:
Release Date : 1994
Trauma written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994 with Medical jurisprudence categories.
Trauma
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Author : William C. Wilson
language : en
Publisher: CRC Press
Release Date : 2007-02-05
Trauma written by William C. Wilson and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-02-05 with Medical categories.
Compiled by internationally recognized experts in trauma critical care,this sourcediscusses the entire gamut of critical care management of the trauma patient and covers several common complications and conditions treated in surgical intensive care units that are not specifically related to trauma. Utilizing evidence-based guidelines where they ex
District Nursing Manual Of Clinical Procedures
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Author : Liz O'Brien
language : en
Publisher: John Wiley & Sons
Release Date : 2012-05-07
District Nursing Manual Of Clinical Procedures written by Liz O'Brien and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-05-07 with Medical categories.
"This manual, the first of its kind focused on district nursing, provides the means to build competence and confidence in nurses new to the community, or developing their skills. The comprehensive and evidence-based content provides essential information for competence in key areas of district nursing." —From the Foreword, by Rosemary Cook CBE, Hon D Lett, MSc, PG Dip, RGN Director, The Queen's Nursing Institute Clinical skills are a fundamental aspect of district nursing care. The District Nursing Manual of Clinical Procedures is a practical, evidence-based manual of clinical skills which reflects the unique challenges of district nursing care within the patient's home. It provides a comprehensive resource for all district nurses, community nurses, students and healthcare professionals involved in the district nursing team, enabling them to practice competently and confidently and deliver clinically effective, person-centred care. The District Nursing Manual of Clinical Procedures addresses the complexity of district nursing care and encompasses key aspects of clinical practice, including decision making in areas that district and community nurses often struggle with or find difficult when they are on their own in a patient's home. It utilises the latest clinical research and expert clinical knowledge to address these challenges, and to provide the underlying theory and evidence for district nursing care. Key features Evidence-based manual of practical clinical skills in district nursing care Clear, user-friendly and easy to understand Contains recommendations for expert care within a patient's own home Addresses key concerns of district and community nurses working on their own within a patient's home Encompasses key aspects of district nursing care Placed in the context of person-centred care All procedures include the rationale for each action - 'why' as well as 'how' This title is also available as a mobile App from MedHand Mobile Libraries. Buy it now from iTunes, Google Play or the MedHand Store.
Ocular Trauma
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Author : H. Mackenzie Freeman
language : en
Publisher:
Release Date : 1979
Ocular Trauma written by H. Mackenzie Freeman and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1979 with Medical categories.
Clinical Nursing Practices
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Author : Sarah Renton
language : en
Publisher: Elsevier Health Sciences
Release Date : 2019-10-08
Clinical Nursing Practices written by Sarah Renton and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-10-08 with Medical categories.
The new edition of Clinical Nursing Practices reflects the many changes in nurse education and practice. A team of clinical and education experts has updated the core practices contained within this text, while to ensure continuity the previous editors have acted as consultants in the development of this edition. To reflect the continuing evolution of nursing and nursing practice, this new 6th edition emphasizes the importance of evidence-based practice, values-based care, person centred care, health and social care integration and interprofessional education. To encourage reflective practice, self-assessment questions remain at the end of each chapter for some of the practices. Where appropriate, certain practices are evidenced mainly by National Guidelines and Standards such as Cardio Pulmonary Resuscitation, Infection Control and Blood Transfusion; consequently, the presentation of the skill or procedure reflects this. The updated text addresses the wider issues which impact on everyday nursing and healthcare practice and is specially written to meet the needs of nurses today. The core philosophy of book, however, remains the same: to encourage its readers to deliver the highest quality care to each individual patient, safely and effectively. Simple and straightforward step-by-step account of the key clinical procedures with clear learning outcomes. For nurses learning procedures for the first time, for newly qualified nurses needing to check their knowledge or for nurses returning to work needing an update or refresher. Equips readers to deliver high quality, safe and effective care to patients. References the new NMC standards of proficiency Updates to all chapters and skills New Action-Rationale format – clearly shows the reasons for performing each procedure. 25 new illustrations New editor team
The Management Of Trauma
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Author : George D. Zuidema
language : en
Publisher: W.B. Saunders Company
Release Date : 1979
The Management Of Trauma written by George D. Zuidema and has been published by W.B. Saunders Company this book supported file pdf, txt, epub, kindle and other format this book has been release on 1979 with Medical categories.
Dermatology E Book
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Author : Jean L. Bolognia
language : en
Publisher: Elsevier Health Sciences
Release Date : 2024-01-20
Dermatology E Book written by Jean L. Bolognia and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-01-20 with Medical categories.
For dermatology residents and trainees, as well as those in clinical practice, Dermatology is the leading reference for understanding, diagnosing, and treating the full spectrum of skin disease—and is the key resource that residents rely on throughout their training and certification. Widely recognized for its easy-in, easy-out approach, this revised 5th Edition turns complex information into user-friendly visual content through the use of clear, templated chapters, digestible artwork, and easy-to-follow algorithms and tables. This two-volume masterwork provides complete, authoritative coverage of basic science, clinical practice of both adult and pediatric dermatology, dermatopathology, and dermatologic surgery—more than any other source, making it the gold standard reference in the field today. Simplifies complex content in a highly accessible, highly visual manner, with 1,100+ tables; 2,600+ figures, including numerous disease classification algorithms as well as diagnostic and therapeutic pathways; and over 1,500 additional figures and tables online. Utilizes weighted differential diagnosis tables and a “ladder” approach to therapeutic interventions. Any additional digital ancillary content may publish up to 6 weeks following the publication date. Features an intuitive organization and color-coded sections that allow for easy and rapid access to the information you need. Retains an emphasis on clinicopathologic correlations, with photomicrographs demonstrating key histologic findings adjacent to clinical images of the same disorder. Contains updated treatment information throughout, including immune checkpoint inhibitors, JAK inhibitors, and monoclonal antibodies for a wide range of conditions such as psoriasis, atopic dermatitis, alopecia areata, vitiligo, and skin cancers. Provides up-to-date information on genetic and molecular markers and next-generation sequencing as it applies to dermatologists. Features new videos, including cryosurgical and suturing techniques, treatment of rhinophyma via electrosection, and neuromodulator treatment of axillary hyperhidrosis. Includes new WHO classifications of skin tumors, new FDA pregnancy drug labeling, and new ACR/EULAR criteria for vasculitis and lupus erythematosus. Includes new sections on confocal microscopy and artificial intelligence.