Tumor Markers Research Perspective
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Tumor Markers Research Perspective
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Author : Geoffrey A. Sinise
language : en
Publisher: Nova Publishers
Release Date : 2007
Tumor Markers Research Perspective written by Geoffrey A. Sinise and has been published by Nova Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with Medical categories.
Tumour markers are molecules occurring in blood or tissue that are associated with cancer, and whose measurement or identification is useful in patient diagnosis or clinical management. This book analyses potential signals of cancerous tumours, otherwise known as markers or indicators. This includes, direct and rapid determination of cancer antigen, potential tumour markers for cholangiocarcinoma, melanoma inhibitory activity, metastatic uveal melanoma, measurement of tumour oxygenation, bladder cancer markers, epithelial cell adhesion and progression markers in prostate tumours.
Tumor Markers Research Focus
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Author : Deborah Chang
language : en
Publisher: Nova Publishers
Release Date : 2007
Tumor Markers Research Focus written by Deborah Chang and has been published by Nova Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with Medical categories.
Tumour markers are molecules occurring in blood or tissue that are associated with cancer, and whose measurement or identification is useful in patient diagnosis or clinical management. This book analyses potential signals of cancerous tumours, otherwise known as markers or indicators. This includes, direct and rapid determination of cancer antigen, potential tumour markers for cholangiocarcinoma, melanoma inhibitory activity, metastatic uveal melanoma, measurement of tumour oxygenation, bladder cancer markers, epithelial cell adhesion and progression markers in prostate tumours.
Progress In Tumor Marker Research
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Author : Lee I. Swenson
language : en
Publisher: Nova Publishers
Release Date : 2007
Progress In Tumor Marker Research written by Lee I. Swenson and has been published by Nova Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with Cancer categories.
Tumour markers are molecules occurring in blood or tissue that are associated with cancer, and whose measurement or identification is useful in patient diagnosis or clinical management. This book analyses potential signals of cancerous tumours, otherwise known as markers or indicators. This includes, direct and rapid determination of cancer antigen, potential tumour markers for cholangiocarcinoma, melanoma inhibitory activity, metastatic uveal melanoma, measurement of tumour oxygenation, bladder cancer markers, epithelial cell adhesion and progression markers in prostate tumours.
Researches On New Generation Tumor Markers
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Author : Yildiz Dincer, Ph.d.
language : en
Publisher:
Release Date : 2019-02-22
Researches On New Generation Tumor Markers written by Yildiz Dincer, Ph.d. and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-02-22 with categories.
Many cancers are associated with the abnormal production of some molecules which can be measured in plasma/urine or can be detected on the surface of resected tumor tissue. These molecules are known as tumor markers. The potential uses of tumor markers are screening in the general population, differential diagnoses of symptomatic patients, clinical staging of cancer, estimating tumor volume, indicating prognosis, monitoring treatment and detecting recurrences. In order to obtain maximum clinical benefit, a tumor marker should have some characteristics. A tumor marker should be tissue-specific. The plasma level of the tumor marker should be in proportion to the size and activity of the tumor. A tumor marker should be present in plasma at a detectable level, even though tumor size is very small. A tumor marker should reflect the altered tumor characteristic as a response to therapy. Unfortunately, currently used tumor markers do not meet all of these criteria. A majority of them are present in normal, benign and tumor tissues, and unfortunately, they are not specific enough to be used for cancer screening in the general population. In addition, conventional tumor markers are poor in reflecting altered tumor behavior in response to anticancer therapy. They are of most value during follow-up appointments. Recent developments in molecular biology have led to the identification of numerous new tumor biomarkers. Firstly, the detection of DNA and RNA freely circulating in blood has provided a new perspective for the early diagnosis of cancer, patient follow-up, and assessment of therapy efficacy. Circulating free nucleic acids can originate from both malignant and non-malignant tissues. Discrimination of tumor cells is based on the presence of tumor-specific genetic and epigenetic alterations. This circulating nucleic acid-based approach is termed a liquid biopsy. Due to its non-invasive and repeatable features, liquid biopsy is a promising tool for cancer patients. It is particularly helpful in cancers where solid tissue biopsies are not feasible, and in the metastatic patients when multiple distinct tumor masses are simultaneously present. As another advantage, liquid biopsy shows the current tumor dynamics during anticancer therapy and drug sensitivities that conventional examinations fail to reflect. Secondly, self-renewable stem cells have the potential to cause cancer. If stem cells are genetically or epienetically changed, their differentiation potential becomes impaired and their proliferative capacity becomes uncontrolled. Current anticancer therapies mostly fail to eradicate cancer stem cells and instead favor expansion of the cancer stem cell pool and/or select for resistant stem cells. Thirdly, microRNAs, non-coding RNAs and transfer RNA fragments found in the bloodstream are candidate markers for the diagnosis and prognosis of different types of cancer. This book provides an overview of these new molecular tumor markers.
Genetic And Phenotypic Markers Of Tumors
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Author : Stuart A. Aaronson
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Genetic And Phenotypic Markers Of Tumors written by Stuart A. Aaronson and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
The study of tumor markers is not only one of the most important but also one that offers one of the richest perspectives in biology and clinical oncology. The aim of scientists in this field is to adduce evidence of a property that is typical of and exclusive to tumor cells, and which is easy to determine, in order to immediately recognize, or even better, to foresee, neoplastic transformations. Unfortunately, despite the large number of scientists and laboratories engaged in this work, the ideal tumor marker has not yet been identified. However, it is worth noting that new trends in molecular biology and immunovirology have recently opened up new avenues that may lead to the eventual resolution of this problem. In this book, different approaches to the identification of tumor markers, from the points of view of biochemistry, immunology, and molecular biology, are compared in order to explore possible interrelationships and to stimulate scientific collaboration among scientists active in these fields, both in basic research and in clinical applications. We wish to thank all the contributors and also the publisher, especially Dr. Robert Andrews, for making the publication of this book possible.
Advances In Cancer Biomarkers
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Author : Roberto Scatena
language : en
Publisher: Springer
Release Date : 2015-11-03
Advances In Cancer Biomarkers written by Roberto Scatena and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-11-03 with Medical categories.
At present there are a growing number of biomolecules under investigation to understand their potential role as cancer biomarker for diagnostic, prognostic and therapeutic purposes. Intriguingly, the state of art on cancer biomarkers research shows interesting and promising results together to clamorous failures. Also from a clinical point of view, there are contradictory results on routine clinical use of the present cancer biomarkers. Some patients may be simply monitored in their course by a periodic blood sample, but sometimes this monitoring shows dramatic limits. A lot of patients show serious and extensive relapses without significant change in serum concentrations of biomarkers tested. Often the physician who should utilize these biomarker does not entirely know their limits and the total potential applications as well and sometimes this knowledge is influenced by economical and marketing strategies. This limited and “polluted” knowledge may have dramatic consequences for patient. The aim of this book is to diffuse all aspects of cancer biomarkers, from their biochemical peculiarities to all clinical implications by passing through their physiology and pathophysiology. This critical approach towards old and new cancer biomarkers should foster a deepened and useful understanding of the diagnostic and prognostic index of these fundamental parameters of laboratory medicine and in the same time facilitating the research of new and more sensitive-specific signals of the cancer cell proliferation.
Biomarkers In Cancer Screening And Early Detection
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Author : Sudhir Srivastava
language : en
Publisher: John Wiley & Sons
Release Date : 2017-06-07
Biomarkers In Cancer Screening And Early Detection written by Sudhir Srivastava and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-06-07 with Medical categories.
Prepared by world leaders on this topic, Biomarkers in Cancer Screening and Early Detection offers a comprehensive, state-of-the-art perspective on the various research and clinical aspects of cancer biomarkers, from their discovery and development to their validation, clinical utility, and use in developing personalized cancer treatment. Offers a comprehensive, state-of-the-art perspective on the various research and clinical aspects of cancer biomarkers Provides immediately actionable information – and hopefully also inspiration – to move discovery and clinical application forward Offers vital knowledge to help develop personalized cancer treatment for individual patients with specific cancers
Precision Oncology And Cancer Biomarkers
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Author : Anne Bremer
language : en
Publisher: Springer Nature
Release Date : 2022-03-29
Precision Oncology And Cancer Biomarkers written by Anne Bremer and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-03-29 with Medical categories.
This open access book reflects on matters of social and ethical concern raised in the daily practices of those working in and around precision oncology. Each chapter addresses the experiences, concerns and issues at stake for people who work in settings where precision oncology is practiced, enacted, imagined or discussed. It subsequently discusses and analyses bioethical dilemmas, scientific challenges and economic trade-offs, the need for new policies, further technological innovation, social work, as well as phenomenological research. This volume takes a broad actor-centred perspective as, whenever cancer is present, the range of actors with issues at stake appears almost unlimited. This perspective and approach opens up the possibility for further in-depth and diverse questions, posed by the actors themselves, such as: How are cancer researchers navigating biological uncertainties? How do clinicians and policy-makers address ethical dilemmas around prioritisation of care? What are the patients’ experiences with, and hopes for, precision oncology? How do policy-makers and entrepreneurs envisage precision oncology? These questions are of great interest to a broad audience, including cancer researchers, oncologists, policy-makers, medical ethicists and philosophers, social scientists, patients and health economists.
Tumor Markers
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Author : Nasser Javadpour
language : en
Publisher:
Release Date : 1987
Tumor Markers written by Nasser Javadpour and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1987 with Immunodiagnosis categories.
Comprehensive Diagnostic Approach To Bladder Cancer
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Author : Marc A. Bjurlin
language : en
Publisher: Springer Nature
Release Date : 2021-09-30
Comprehensive Diagnostic Approach To Bladder Cancer written by Marc A. Bjurlin and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-09-30 with Medical categories.
This succinct yet comprehensive book describes current and emerging concepts in risk stratification, detection, and staging of bladder cancer. Divided into two distinct sections, the first section focuses on contemporary and novel imaging modalities in bladder cancer staging. The second section illuminates advanced optical techniques and tumor markers for bladder cancer detection. The volume also addresses such topics as novel immuno-positron emission tomography radiotracers, imaging modalities for monitoring of tumor response, and non-invasive urine biomarkers such as current and emerging molecular markers for bladder cancer screening, early diagnosis, and surveillance. Comprehensive Diagnostic Approach to Bladder Cancer: Molecular Imaging and Biomarkers is written by experts in the field and provides a valuable resource for urologists, oncologists, urologic oncologists, radiation oncologists, allied health professionals, residents, and fellows who treat and manage bladder cancer.