Understanding Enzymes
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Understanding Enzymes
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Author : Trevor Palmer
language : en
Publisher: Ellis Horwood
Release Date : 1991
Understanding Enzymes written by Trevor Palmer and has been published by Ellis Horwood this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991 with Science categories.
This third edition of Understanding Enzymes has been carefully and thoroughly updated and revised. The content of the book remains the same as for previous editions, providing a clear and lucid picture of the principles of enzymology.
Understanding Enzymes
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Author : Allan Svendsen
language : en
Publisher: CRC Press
Release Date : 2016-04-27
Understanding Enzymes written by Allan Svendsen and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-27 with Mathematics categories.
Understanding Enzymes: Function, Design, Engineering, and Analysis focuses on the understanding of enzyme function and optimization gained in the past decade, past enzyme function analysis, enzyme engineering, and growing insights from the simulation work and nanotechnology measurement of enzymes in action in vitro or in silico. The book also prese
Understanding Enzymes
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Author : T. Palmer
language : en
Publisher:
Release Date : 1985-02-01
Understanding Enzymes written by T. Palmer and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1985-02-01 with categories.
Understanding Enzymes
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Author : Palmer
language : en
Publisher:
Release Date : 1985-02-01
Understanding Enzymes written by Palmer and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1985-02-01 with categories.
Understanding Enzymes
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Author : Trevor Palmer
language : en
Publisher:
Release Date : 1985
Understanding Enzymes written by Trevor Palmer and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1985 with Science categories.
This clear and lucid book helps towards an understanding of the principles of enzymology, a subject with a somewhat undeserved reputation for being difficult. The subject is explained most carefully, without rushing or cutting corners, in a coverage which is balanced, readable and comprehensive, accounting for both theory and applications. The book will act as a bridge for those wishing to progress to more advanced and specialised areas. New material has been added since publication of the first edition, revealing advances made since 1980, including NMR spectroscopy, HPLC, immunoassay, genetic engineering and structures of oligomeric enzymes. Fresh and stimulating problems have been devised, diagrams redrawn and sections on obsolete techniques removed to make way for the new material. The approach taken throughout encourages, where appropriate, correct answers to problems, thereby reinforcing the reader's understanding of enzymology by facing real-life difficulties.
Activation And Detoxification Enzymes
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Author : Chang-Hwei Chen
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-11-16
Activation And Detoxification Enzymes written by Chang-Hwei Chen and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-11-16 with Medical categories.
Humans are exposed to foreign compounds such as drugs, household products and environmental chemicals by swallowing or breathing. Also, food is considered a foreign compound. Such foreign compounds can be non-essential and non-functional to life, and commonly are referred to as xenobiotics. Some xenobiotics are not toxic; however, many of them are potentially toxic or become toxic after conversion to metabolic intermediates. A considerable number of foreign compounds belong to non-polar, lipophilic substances. Lipophilic compounds are not soluble in water. Metabolic conversion of lipophilic foreign compounds to facilitate their removal from the body is essentially carried out by biochemical reactions catalyzed by two classes of metabolizing enzymes, namely, activation enzymes and detoxification enzymes. Activation enzyme-catalyzed functionalization reaction introduces a functional group to a lipophilic compound. Functionalization modifies many foreign compounds to form reactive intermediates capable of interacting with cellular components (proteins, DNA and lipids), leading to a variety of conditions for diseases. Functionalized compounds are further metabolized through detoxification enzyme-catalyzed reactions, which result in an increase in the solubility of parent compounds and an inactivation of metabolic intermediates, thus facilitating their excretion from the body. To minimize the exposure of potentially toxic metabolic intermediates, it is essential to keep them at a minimum level. Extensive investigations have revealed that foreign compound-metabolizing enzymes exhibit genetic polymorphisms. Variations in their activities can produce different results as to the susceptibility to potential toxic effects. Moreover, the expressions of activation enzymes and detoxification enzymes are inducible. A number of chemical compounds are capable of acting as modulators for these two classes of enzymes. These findings have lead to the proposal of modulating metabolizing enzymes as a useful approach for human health benefits. Importantly, many of these chemical compounds are present in human daily diets. There are many advances that have been made in the past decades towards the understanding of functions and implications of activation enzymes and detoxification enzymes. An organized, concise overview is needed for the readers who are initially exposed to this important subject, particularly for students and researchers in the areas of biomedical sciences, biochemistry, nutrition, pharmacology and chemistry. This book is intended to serve this purpose as an introduction to the subject. Furthermore, major topics in the book, excluding catalytic reactions and structural properties, may have interest to other readers who have knowledge of basic sciences and understanding enzyme related information. The book discusses subjects associated with foreign compound metabolizing enzymes with emphasis on biochemical aspects, including lipophilic foreign compounds, catalytic properties, reactive intermediates, biomedical and biochemical effects, genetic polymorphisms, enzyme inducibility, enzyme modulation for health benefits, dietary related enzyme modulators, and structural characteristics of enzyme inducers.
Fundamentals Of Enzyme Kinetics
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Author : Athel Cornish-Bowden
language : en
Publisher: Portland Press
Release Date : 1995
Fundamentals Of Enzyme Kinetics written by Athel Cornish-Bowden and has been published by Portland Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995 with Science categories.
Since the first edition of the book was published in 1979, the development of techniques for studying and manipulating genes has transformed biochemistry. Nonetheless, enzymes remain at the heart of all living systems, and an understanding of how they operate is vital for understanding the chemistry of life. This book describes the principles of enzyme kinetics, with an emphasis on principles rather than an encyclopaedic accumulation of facts, to allow readers to fill in gaps themselves and proceed in the subject as far as they need to go. In this way it provides the basis for understanding enzyme kinetics, whether at the level of the undergraduate, the research student or the researcher.
Medical Enzymology
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Author : Tarek H. El-Metwally
language : en
Publisher:
Release Date : 2011
Medical Enzymology written by Tarek H. El-Metwally and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with Biocatalysis categories.
Understanding enzyme kinetics and structure-function relationship enables us to explain the metabolic regulation and integration. The information also helps us understanding action of specific toxins, drug metabolism and disease pathogenesis. This enables us to invent suitable interventions to circumvent unfavourable and invest the favourable effects on enzymes and to design more efficient biocatalysts for therapeutic and industrial uses. This book presents all of the fundamental knowledge of enzymology in a very simple way.
Unveiling Enzyme Kinetics The Michaelis Menten Equation Explained
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Author : Mourine
language : en
Publisher:
Release Date : 2024-06-07
Unveiling Enzyme Kinetics The Michaelis Menten Equation Explained written by Mourine and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-06-07 with categories.
Understanding Biochemistry
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Author :
language : en
Publisher:
Release Date : 2015
Understanding Biochemistry written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015 with categories.