Unfolded
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Unfolded Proteins
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Author : Trevor P. Creamer
language : en
Publisher: Nova Publishers
Release Date : 2008
Unfolded Proteins written by Trevor P. Creamer and has been published by Nova Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with Science categories.
The word revolution has a number of definitions (The American Heritage Dictionary, 2006). The one most pertinent to this series and volume is 'a sudden or momentous change in a situation'. Recent years have seen an unprecedented explosion of interest in unfolded proteins in all of their various forms. Coupled with this increase in interest we have seen momentous changes in the way unfolded proteins are viewed. Two particular paradigms have come under close scrutiny: unfolded proteins are disordered random coils devoid of persistent structure, and protein function first requires protein structure. The first of these is currently a hotly debated subject. The second paradigm we can safely claim has been overturned. There is a second definition of revolution that is quite relevant to a significant portion of the work reviewed herein, in particular those chapters dealing with local and persistent structure in unfolded proteins. That definition is 'a turning or rotational motion about an axis' (The American Heritage Dictionary, 2006). About four decades ago, Charles Tanford (1968) demonstrated that highly denatured proteins possess hydrodynamic properties consistent with Paul Flory's random coil (Flory, 1969). Given that the Flory random coil definition included the stipulation that conformers making up the denatured state ensemble would differ in energy by just a few kT, there has been the assumption that denatured states must therefore be completely random in nature with no persistent structure or biases towards particular conformers. Notably however, Tanford did note the random coil-like hydrodynamic data he obtained did not necessarily rule out the presence of structure in denatured proteins (Tanford, 1968). Around the same time, Sam Krimm and M. Lois Tiffany noted that the CD spectra they obtained for proteins in the presence of high concentration of chemical denaturants had similarities to spectra obtained for homopolymers of proline, lysine, and glutamic acid in water (Tiffany and Krimm, 1968a, 1968b, 1973, 1974). Homopolymers of these residues were known to adopt the left-handed polyproline II conformation, leading Tiffany and Krimm to hypothesise that highly denatured proteins possess significant polyproline II helix content. Of these two views, that espousing the lack of structure in denatured proteins became more widely adopted and was, over time, adopted as a central paradigm in protein folding. As several of the chapters in this volume note, a Tiffany and Krimm-like view appears to be, to some extent, the more correct one. The level to which it is correct is still unknown, although it is clear that the polyproline II helical conformation is not the only, perhaps not even the most common, persistent conformation present in unfolded proteins. Thus we have come through a full circle or revolution. (from the preface)
Unfolded
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Author : Petra Schmidt
language : en
Publisher: Walter de Gruyter
Release Date : 2012-11-05
Unfolded written by Petra Schmidt and has been published by Walter de Gruyter this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-11-05 with Design categories.
In Unfolded—Paper in Design, Art, Architecture and Industry paper conquers the third dimension and demonstrates the undreamed-of possibilities it holds today for lightweight construction, product design, fashion and art. From "Paper", the collection of bags by Stefan Diez, to Konstantin Grcic’s paper models and the scented paper garments of Issey Miyake, this book presents paper as a high-quality contemporary and ecological material. An enormous selection of projects, the lavish design and numerous illustrations provide designers with invaluable inspiration for their work. The content core of the book is a comprehensive list of state-of-the-art paper products and innovative paper technologies, supporting designers in their everyday work with detailed information on the "high-tech" material paper. From Japanese washi paper and paper foam, to ceramic paper and carbon fiber paper, Unfolded presents the latest in research and development, as well as the most important methods and technologies in handcrafts and industry.
Indian Cooking Unfolded
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Author : Raghavan Iyer
language : en
Publisher: Hachette UK
Release Date : 2013-07-30
Indian Cooking Unfolded written by Raghavan Iyer and has been published by Hachette UK this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-07-30 with Cooking categories.
Love Indian food but feel it's too daunting to recreate at home? Those complex authentic flavors! Those dozens of spice blends! The long prep time! Fear not. Award-winning cooking teacher Raghavan Iyer puts the breeze and ease into Indian cooking. Taking a heavily illustrated, step-by-step approach, he introduces cooks to one of the world's most popular cuisines. With his natural charm and enthusiasm, Raghavan begins each chapter by explaining the recipe choices, what techniques are included, and a suggested order in which to approach the recipes. The book's 100 authentic recipes use only ingredients readily available at the local supermarket. Taking into account time restraints, each dish can be quickly assembled and will give home cooks the confidence to create knockout Tandoori Chicken, Coconut Squash with Chiles, Turmeric Hash Browns, Saffron-Pistachio Ice Cream Bars, and Mango Bread Pudding with Chai Spices. From basic breads to chutneys and savory pickles, from tasty dal to fragrant basmati rice pilafs, from crispy starters to enjoy with a Slumdog Martini, Indian Cooking Unfolded is a 21st-century approach to one of the most ancient—and popular—cuisines.
Unfolding Meaning
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Author : David Bohm
language : en
Publisher: Routledge
Release Date : 2006-11-22
Unfolding Meaning written by David Bohm and has been published by Routledge this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-11-22 with Philosophy categories.
First published in 1987. In Unfolding Meaning, the author, one of the most provocative and original thinkers of our time, argues that there are other ways of thinking to bring about a different, more harmonious reality. Our fragmented, mechanistic notion of order derives from the modem conception that our earth is only part, not - as it was with the Greeks - the centre, of the immense universe of material bodies. The implications of this idea permeate modem science and technology today and also our general attitude to life.
The Unfolded Folded
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Author : Angie Waller
language : en
Publisher:
Release Date : 2017-05-26
The Unfolded Folded written by Angie Waller and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-05-26 with categories.
Automatic writing session with Google Translate.
Iniquity Unfolded An Account Of The Treatment Of Mr F By The Deacons In South Boston And Others Written By Himself
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Author : Joy Hamlet FAIRCHILD
language : en
Publisher:
Release Date : 1844
Iniquity Unfolded An Account Of The Treatment Of Mr F By The Deacons In South Boston And Others Written By Himself written by Joy Hamlet FAIRCHILD and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1844 with categories.
Couture Unfolded
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Author : Brunella Giannangeli
language : en
Publisher:
Release Date : 2012-01-01
Couture Unfolded written by Brunella Giannangeli and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-01-01 with Dressmaking categories.
Folds are currently in a rising moment and this book teaches how to manipulate and finish them in order to obtain that personal touch so crucial in the world and business of fashion. Couture Unfolded is a most complete sourcebook of folding finishes through simple illustrations and detailed instructions.
Brexit Unfolded
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Author : Chris Grey
language : en
Publisher: Biteback Publishing
Release Date : 2021-06-23
Brexit Unfolded written by Chris Grey and has been published by Biteback Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-06-23 with History categories.
"Masterful" – Ian Dunt "Fascinating" – Professor Brian Cox "Vital" – David Miliband *** Britain's 2016 vote to leave the EU divided the nation, unleashing years of political turmoil. Today, many remain unreconciled to Brexit whilst, in a tragic irony, some of those most committed to it are angry and dissatisfied with what was delivered. In this clear-headed assessment, Chris Grey argues that this painful legacy was all but inevitable, skilfully unpacking how and why the promise of Brexit dissolved during the confusing and often dramatic events that followed the referendum. Now fully updated with an afterword covering each element of the Brexit debate since the end of the transition period in 2021, this new edition remains the essential guide to one of the most bitterly contested issues of our time.
The Unfolding Gospel
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Author : John P. Bowen
language : en
Publisher: Fortress Press
Release Date : 2021-07-06
The Unfolding Gospel written by John P. Bowen and has been published by Fortress Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-07-06 with Religion categories.
Many congregations and their leaders are discouraged about the future of the church. John Bowen's conviction is that the solution is to be found not in new programs or strategies but in a recovery of theological vision--that of Jesus and his gospel, which transforms every aspect of life. This vision restores hope in the only way realistically possible._ Words like mission, discipleship, church, evangelism, renewal, and church planting are used like billiard balls--all rolling around a single table, unconnected and bouncing randomly off one another. This book pulls these ideas together into a coherent and organic whole. The gospel is the hermeneutical key for understanding each of these topics and what draws them together. Thus, chapter 1 is an exposition of the gospel (God's determination to make all things new through Jesus Christ). Chapter 2 discusses discipleship (we only understand discipleship in light of the gospel), and chapter 3 covers church (we only understand church if we understand discipleship). Chapter 4 considers culture as the arena in which the gospel is lived and talked about, and chapter 5 builds on that with a discussion of translation, not only as a missional necessity but as a ministry which itself incarnates the nature of the gospel. The remaining chapters (on evangelism, the future of "inherited churches," church planting, and leadership) demonstrate how the gospel is the integration point for all._ The author's hope is that church leaders--evangelical and mainline, young and old, emerging and traditional, present and future--will have a transformative "Aha!" moment as this gospel hypothesis unfolds._
The Unfolding Of Personality As The Chief Aim In Education
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Author : Harry Thiselton Mark
language : en
Publisher: Рипол Классик
Release Date : 1910
The Unfolding Of Personality As The Chief Aim In Education written by Harry Thiselton Mark and has been published by Рипол Классик this book supported file pdf, txt, epub, kindle and other format this book has been release on 1910 with History categories.
