Value Of Adenosine Deaminase Ada In Diagnosis Of Tuberculous Pleurisy
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Value Of Adenosine Deaminase Ada In Diagnosis Of Tuberculous Pleurisy
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Author : Zay Soe
language : en
Publisher: LAP Lambert Academic Publishing
Release Date : 2012
Value Of Adenosine Deaminase Ada In Diagnosis Of Tuberculous Pleurisy written by Zay Soe and has been published by LAP Lambert Academic Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with categories.
In Myanmar, tuberculosis is one of the major public health problems and recent estimates suggest that 1.66% of Myanmar population become infected with tuberculosis every year. The common causes of pleural effusion in Myanmar are tuberculosis and bronchogenic carcinoma. Evaluation of exudative pleural effusion includes studies of pleural fluid and blind needle biopsy of pleura using Abram's pleural biopsy needle or Cope's biopsy needle. However following these procedures some patients are still undiagnosed. Correcting this diagnostic deficiency the author's main interest is pleural fluid Adenosine deaminase to search for tuberculosis in pleural space. Within the study period, 187 patients with various causes of pleural effusion admitted to the Department of Respiratory Medicine, Yangon General Hospital, Myanmar were studied. In this study, the author found out pleural fluid Adenosine deaminase assay is highly sensitive and specific test suitable for rapid diagnosis of tuberculous pleural effusion.
Diagnosis Of Tuberculous Pleurisy With Combination Of Adenosine Deaminase And Interferon Immunospot Assay In A Tuberculosis Endemic Population
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Author :
language : en
Publisher:
Release Date : 2017
Diagnosis Of Tuberculous Pleurisy With Combination Of Adenosine Deaminase And Interferon Immunospot Assay In A Tuberculosis Endemic Population written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017 with categories.
Abstract : Abstract: The aim of this study was to identify the optimal cut-off value of T cell enzyme-linked immunospot assay for tuberculosis (T-SPOT.TB) and evaluate its diagnostic performance alone (in the peripheral blood) or in combination with the adenosine deaminase (ADA) activity test (in peripheral blood and the pleural fluid) in patients with tuberculous pleurisy. Adult patients presenting with pleural effusion were included in this prospective cohort study. Tuberculous pleurisy was diagnosed by T-SPOT.TB in peripheral blood and a combination of T-SPOT.TB and ADA activity test in pleural fluid and peripheral blood. Receiver operating characteristic (ROC) curve in combination with multivariate logistic regression was used to evaluate the diagnostic performance of the assays. Among a total of 189 patients with suspected tuberculous pleurisy who were prospectively enrolled in this study, 177 patients were validated for inclusion in the final analysis. ROC analysis revealed that the area under the ROC curve (AUC) for T-SPOT.TB in pleural fluid and peripheral blood was 0.918 and 0.881, respectively, and for the ADA activity test in pleural fluid was 0.944. In addition, 95.5 spot-forming cells (SFCs)/2.5 × 10 5 cells were determined as the optimal cut-off value for T-SPOT.TB in pleural fluid. Parallel combination of T-SPOT.TB and ADA activity test in pleural fluid showed increased sensitivity (96.9%) and specificity (87.5%), whereas serial combination showed increased specificity (97.5%). The combination of 3 assays had the highest sensitivity at 97.9%, with an AUC value of 0.964. T-SPOT.TB in pleural fluid performed better than that in peripheral blood and the ADA activity test in pleural fluid for tuberculous pleurisy diagnosis. The optimal cut-off value of T-SPOT.TB in pleural fluid was 95.5 SFCs/2.5 × 10 5 cells. Combination of 3 assays might be a promising approach for tuberculous pleurisy diagnosis.
Pleural Diseases
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Author : Richard W. Light
language : en
Publisher: Lippincott Williams & Wilkins
Release Date : 2007
Pleural Diseases written by Richard W. Light and has been published by Lippincott Williams & Wilkins this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with Medical categories.
Thoroughly updated for its Fifth Edition, Dr. Light's classic text provides a focused, single-authored perspective on the pathophysiology, clinical manifestations, diagnosis, and management of pleural diseases. This edition has three new chapters on physiological effects of a pneumothorax or pleural effusion, animal models in pleural investigation, and cytokines and the pleura. Other chapters present significant updates on use of thoracoscopy in diagnosis of pleural effusions and on new diagnostic tests for mesothelioma, parapneumonic effusion, and effusions due to congestive heart failure. Also included are discussions of recent advances in the therapy of malignant pleural effusions, mesothelioma, and parapneumonic effusions.
Clinical Tuberculosis
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Author : Peter D. O. Davies
language : en
Publisher: CRC Press
Release Date : 2014-04-30
Clinical Tuberculosis written by Peter D. O. Davies and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-04-30 with Medical categories.
Completely updated and revised, Clinical Tuberculosis continues to provide the TB practitioner-whether in public health, laboratory science or clinical practice-with a synoptic and definitive account of the latest methods of diagnosis, treatment and control of this challenging and debilitating disease.New in the Fifth Edition:Gamma interferon-based
Wesleyan University 1831 1910
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Author : David B. Potts
language : en
Publisher: Wesleyan University Press
Release Date : 1999-03-30
Wesleyan University 1831 1910 written by David B. Potts and has been published by Wesleyan University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999-03-30 with Education categories.
A lively narrative connecting Wesleyan University's early history to economic, religious, urban, and educational developments in 19th-century America.
Tuberculosis In Adults And Children
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Author : Dorothee Heemskerk
language : en
Publisher: Springer
Release Date : 2015-07-17
Tuberculosis In Adults And Children written by Dorothee Heemskerk and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-07-17 with Medical categories.
This work contains updated and clinically relevant information about tuberculosis. It is aimed at providing a succinct overview of history and disease epidemiology, clinical presentation and the most recent scientific developments in the field of tuberculosis research, with an emphasis on diagnosis and treatment. It may serve as a practical resource for students, clinicians and researchers who work in the field of infectious diseases.
Global Tuberculosis Control
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Author : World Health Organization
language : en
Publisher: World Health Organization
Release Date : 2009
Global Tuberculosis Control written by World Health Organization and has been published by World Health Organization this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with Business & Economics categories.
This report is WHO's thirteenth annual report on global tuberculosis (TB) control in a series that started in 1997. It presents WHO's latest assessment of the epidemiological burden of TB (numbers of cases and deaths), as well as progress towards the 2015 targets for global TB control that have been established within the context of the Millennium Development Goals (MDGs). It also includes a thorough analysis of implementation and financing of the WHO's Stop TB Strategy and the Stop TB Partnership's Global Plan to Stop TB, since in combination these have set out how TB control needs to be implemented and funded to achieve the 2015 targets. The report gives particular attention to the period 2006-2009, but selected epidemiological, implementation and financial data are presented for previous years as well. This includes epidemiological data back to 1990 and financial data back to 2002.Bringing together data reported by 196 out of 212 countries and territories in 2008, as well as data collected from these countries and territories in previous years, "Global Tuberculosis Control 2009" is the definitive source of information about the national and international response to the worldwide TB epidemic.
Textbook Of Pleural Diseases Second Edition
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Author : Richard W. Light
language : en
Publisher: CRC Press
Release Date : 2008-04-25
Textbook Of Pleural Diseases Second Edition written by Richard W. Light and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-04-25 with Medical categories.
This internationally renowned reference work is a fully updated and expanded second edition of the most comprehensive title available on pleural diseases. Building on the many strengths of the highly respected first edition, the book features a detailed yet lucid basic science section to support understanding of the physiological and pathophysiological mechanisms that underlie diseases of the pleura. This is followed by a wide-ranging series of clinical chapters, discussing both familiar and less common aspects of pleural diseases. Chapters in the clinical section are written in an accessible and uniform style, making extensive use of illustrative material and covering definition, incidence and epidemiology, etiology and pathogenesis, clinical presentation, investigations, treatments, possible complications and directions for future development. State-of-the-art scientific knowledge is presented at an appropriate level for the practicing clinician, and published management guidelines are included where relevant. Each chapter concludes with a summary of its 'key points', highlighting practical messages regarding patient management for the reader. Textbook of Pleural Diseases is an indispensable reference for pulmonary physicians and trainees worldwide.
The Diagnostic Value Of Adenosine Deaminase Activity In The Ascitic Fluid Of Patients With Tuberculous Peritonitis
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Author : Michael D. Voigt
language : en
Publisher:
Release Date : 1988*
The Diagnostic Value Of Adenosine Deaminase Activity In The Ascitic Fluid Of Patients With Tuberculous Peritonitis written by Michael D. Voigt and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988* with Adenosine categories.
Clinical Guide To Laboratory Tests
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Author : Norbert W. Tietz
language : en
Publisher: Saunders
Release Date : 1995
Clinical Guide To Laboratory Tests written by Norbert W. Tietz and has been published by Saunders this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995 with Medical categories.
The 3rd edition presents information on common tests as well as rare and highly specialized tests and procedures. Biological variables that may affect test results are discussed, and a focus is placed on reference ranges, diagnostic information, clinical interpretation of laboratory data, interferences, and specimen types. Includes a section on molecular pathology, and tests have been added in the areas of endocrinology, immunochemistry, serologic hepatitis testing, and more.