Verdades Pen Ltimas
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The Mirror Man
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Author : Lars Kepler
language : en
Publisher: Bonnier Zaffre Ltd.
Release Date : 2022-01-06
The Mirror Man written by Lars Kepler and has been published by Bonnier Zaffre Ltd. this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-06 with Fiction categories.
Seventeen-year-old Jenny is abducted in broad daylight and taken to a dilapidated, isolated house where she is chained and caged along with several other girls. Their captor is unpredictable, and as wily as he is cruel: he foils every one of their desperate attempts to escape . . . and once caught they rarely survive their punishment. Five years later, Jenny is found dead in a public park, and the police are scrambling to find a lead among the scant evidence. But Detective Joona Linna realizes that this murder has an eerie connection to a death that was declared a suicide years before. And now when Mia, a seventeen-year-old orphan, goes missing, it becomes clear to Joona that they are dealing with a serial killer-and the murderous rampage has just begun. As the police close in on the killer, Mia and her fellow captives are plunged into ever greater danger, and Joona finds himself in a seemingly impossible race against time to save their young lives.
Translational Medicine
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Author : Joy A. Cavagnaro
language : en
Publisher: CRC Press
Release Date : 2021-11-26
Translational Medicine written by Joy A. Cavagnaro and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-26 with Medical categories.
Translational Medicine: Optimizing Preclinical Safety Evaluation of Biopharmaceuticals provides scientists responsible for the translation of novel biopharmaceuticals into clinical trials with a better understanding of how to navigate the obstacles that keep innovative medical research discoveries from becoming new therapies or even making it to clinical trials. The book includes sections on protein-based therapeutics, modified proteins, oligonucleotide-based therapies, monoclonal antibodies, antibody–drug conjugates, gene and cell-based therapies, gene-modified cell-based therapies, combination products, and therapeutic vaccines. Best practices are defined for efficient discovery research to facilitate a science-based, efficient, and predictive preclinical development program to ensure clinical efficacy and safety. Key Features: Defines best practices for leveraging of discovery research to facilitate a development program Includes general principles, animal models, biomarkers, preclinical toxicology testing paradigms, and practical applications Discusses rare diseases Discusses "What-Why-When-How" highlighting different considerations based upon product attributes. Includes special considerations for rare diseases About the Editors Joy A. Cavagnaro is an internationally recognized expert in preclinical development and regulatory strategy with an emphasis on genetic medicines.. Her 40-year career spans academia, government (FDA), and the CRO and biotech industries. She was awarded the 2019 Arnold J Lehman Award from the Society of Toxicology for introducing the concept of science-based, case-by-case approach to preclinical safety evaluation, which became the foundation of ICH S6. She currently serves on scientific advisory boards for advocacy groups and companies and consults and lectures in the area of preclinical development of novel therapies. Mary Ellen Cosenza is a regulatory toxicology consultant with over 30 years of senior leadership experience in the biopharmaceutical industry in the U.S., Europe, and emerging markets. She has held leadership position in both the American College of Toxicology (ACT) and the International Union of Toxicology (IUTOX) and is also an adjunct assistant professor at the University of Southern California where she teaches graduate-level courses in toxicology and regulation of biologics.
A Breath Of Life
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Author : Clarice Lispector
language : en
Publisher: Random House
Release Date : 2022-07-28
A Breath Of Life written by Clarice Lispector and has been published by Random House this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-07-28 with Fiction categories.
A Breath of Life is Clarice Lispector's final novel, 'written in agony', which she did not live to see published. Sensual and mysterious, it is a mystical dialogue between a god-like author and the creation he breathes life into: the speaking, shifting, indefinable Angela Pralini. As he has created Angela, so, eventually, he must let her die, for life is merely 'a kind of madness that death makes.' This is a unique, elegiac meditation on the creation of life, and of art.
The One And Only Sparkella
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Author : Channing Tatum
language : en
Publisher: Feiwel & Friends
Release Date : 2021-05-04
The One And Only Sparkella written by Channing Tatum and has been published by Feiwel & Friends this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-05-04 with Juvenile Fiction categories.
An Instant #1 New York Times Bestseller! A Publishers Weekly Bestseller! Leading actor, producer and director Channing Tatum's picture book debut, The One and Only Sparkella is a charming ode to self-esteem and the love between a father and daughter—illustrated by Kim Barnes. Ella is excited for her first day at a new school. Glimmering pencil case? Check! Shimmering backpack? Check! Glittery ribbons in her hair? Check! She can't wait to meet the other kids and share her sparkly personality. But her first day doesn't go quite as planned: Her new classmates don't like her disco-ball shoes, her PB&J-with-sprinkles sandwich, or her rainbow-y unicorn painting. Ella decides to try to be less sparkly at school the next day so the other kids won't make fun of her. But with a little help from her dad, she soon learns the importance of just being herself, no matter what other people say.
The Life And Death Of Democracy
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Author : John Keane
language : en
Publisher: Simon and Schuster
Release Date : 2009-06-01
The Life And Death Of Democracy written by John Keane and has been published by Simon and Schuster this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-06-01 with History categories.
John Keane's The Life and Death of Democracy will inspire and shock its readers. Presenting the first grand history of democracy for well over a century, it poses along the way some tough and timely questions: can we really be sure that democracy had its origins in ancient Greece? How did democratic ideals and institutions come to have the shape they do today? Given all the recent fanfare about democracy promotion, why are many people now gripped by the feeling that a bad moon is rising over all the world's democracies? Do they indeed have a future? Or is perhaps democracy fated to melt away, along with our polar ice caps? The work of one of Britain's leading political writers, this is no mere antiquarian history. Stylishly written, this superb book confronts its readers with an entirely fresh and irreverent look at the past, present and future of democracy. It unearths the beginnings of such precious institutions and ideals as government by public assembly, votes for women, the secret ballot, trial by jury and press freedom. It tracks the changing, hotly disputed meanings of democracy and describes quite a few of the extraordinary characters, many of them long forgotten, who dedicated their lives to building or defending democracy. And it explains why democracy is still potentially the best form of government on earth -- and why democracies everywhere are sleepwalking their way into deep trouble.
Linguagens Da Verdade Ensaios 2003 2020
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Author : Salman Rushdie
language : pt-BR
Publisher: Leya
Release Date : 2023-04-01
Linguagens Da Verdade Ensaios 2003 2020 written by Salman Rushdie and has been published by Leya this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-04-01 with Fiction categories.
Salman Rushdie é celebrado como «um mestre da narrativa contínua» (The New Yorker), iluminando verdades da nossa sociedade e cultura através da sua prosa deslumbrante e, muitas vezes, cáustica. Esta coletânea de textos de não-ficção reúne ensaios, críticas e discursos perspicazes e inspiradores, que se focam na relação de Rushdie com a palavra escrita e fortalecem o seu lugar como um dos pensadores mais originais do nosso tempo. Linguagens da Verdade reúne textos escritos entre 2003 e 2020 e demonstra o envolvimento intelectual de Salman Rushdie com certos períodos de mudanças culturais. Mergulhando o leitor numa ampla variedade de assuntos, explora a natureza do ato de narrar como uma necessidade humana, e o resultado é uma carta de amor à literatura. Rushdie analisa o que obras de autores desde Shakespeare e Cervantes até Samuel Beckett, Eudora Welty e Toni Morrison significam para ele, tanto na página impressa como a nível pessoal. Ao mesmo tempo, tenta aprofundar a natureza da «verdade», deleitando-se com a vibrante maleabilidade da linguagem e das linhas criativas que podem unir arte e vida, e revisita temas como a migração, o multiculturalismo e a censura.
A Busca Da Verdade No Processo Penal
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Author : Antonio Carlos de Faria Silva
language : pt-BR
Publisher: Editora Baraúna
Release Date : 2018-01-01
A Busca Da Verdade No Processo Penal written by Antonio Carlos de Faria Silva and has been published by Editora Baraúna this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-01-01 with Law categories.
Dentro do entendimento de que a função das decisões do juiz é a construção da paz social e da justiça, não há dúvida de que o erro no processo penal cause um prejuízo irreparável. Objetivou-se apresentar a construção da verdade no processo penal, diante dos novos paradigmas do conhecimento, e estudar os fundamentos e os graus de certeza das decisões do juiz no processo penal.
The Truth About You Me
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Author : Amanda Grace
language : en
Publisher: North Star Editions, Inc.
Release Date : 2013-09-08
The Truth About You Me written by Amanda Grace and has been published by North Star Editions, Inc. this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-09-08 with Young Adult Fiction categories.
Madelyn is smart for her age, so she’s taking classes at community college, earning credits for high school and college simultaneously. Her biology professor is funny, hot, and oh so interested. She knows that if she told him she’s only sixteen, their relationship would be over. So Madelyn makes a simple decision: She won’t tell him.
Joe Gould S Secret
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Author : Joseph Mitchell
language : en
Publisher: Random House
Release Date : 2019-10-03
Joe Gould S Secret written by Joseph Mitchell and has been published by Random House this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-10-03 with Biography & Autobiography categories.
‘It's a masterpiece, of course, but more than that it shows that there is some such thing as being a simple observer’ Nicci French, Independent It was 1932 when Joseph Mitchell first came across Joe Gould, a Harvard-educated vagrant of Greenwich Village. Penniless, filthy, scurrilous, charming, thieving, Joe Gould was widely considered a genius. He was working on a book he called an Oral History – the longest book ever written he claimed, formed of recorded conversations set down in exercise books. Of course, when Gould died the great epic was nowhere to be found. This compelling portrait of a true New York eccentric, a man who embodied the disconnected, delusional nature of real life, was Mitchell’s personal enquiry into the agony of writer’s block. Joe Gould's Secret can be found in the longer collection of Mitchell's writing Up in the Old Hotel.
Compromisso Com A Verdade
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Author : Klaus
language : pt-BR
Publisher: Klaus
Release Date : 2023-12-06
Compromisso Com A Verdade written by Klaus and has been published by Klaus this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-12-06 with Fiction categories.
Imagine um livro de humor politicamente incorreto que destemidamente se utiliza de fake news para criticar os absurdos da atual sociedade pós-moderna. Pois esse livro existe. Valendo-se de sua característica escrita ácida, debochada e altamente sarcástica, Klaus arrisca sua reputação e até sua integridade física para dizer o indizível. Com seus textos "inclusivos", a obra promete ofender indiscriminadamente uma variada gama de grupos, em especial as minorias identitárias e os jovens das gerações Y e Z. COMPROMISSO COM A VERDADE é o livro que o establishment não quer que você leia. Compre antes que seja banido por ordem judicial! O MINISTÉRIO DA SAÚDE ADVERTE: ler este livro sem o devido preparo psicológico pode causar danos cerebrais irreversíveis.