Viagem Solit Ria
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Translational Medicine
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Author : Joy A. Cavagnaro
language : en
Publisher: CRC Press
Release Date : 2021-11-26
Translational Medicine written by Joy A. Cavagnaro and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-26 with Medical categories.
Translational Medicine: Optimizing Preclinical Safety Evaluation of Biopharmaceuticals provides scientists responsible for the translation of novel biopharmaceuticals into clinical trials with a better understanding of how to navigate the obstacles that keep innovative medical research discoveries from becoming new therapies or even making it to clinical trials. The book includes sections on protein-based therapeutics, modified proteins, oligonucleotide-based therapies, monoclonal antibodies, antibody–drug conjugates, gene and cell-based therapies, gene-modified cell-based therapies, combination products, and therapeutic vaccines. Best practices are defined for efficient discovery research to facilitate a science-based, efficient, and predictive preclinical development program to ensure clinical efficacy and safety. Key Features: Defines best practices for leveraging of discovery research to facilitate a development program Includes general principles, animal models, biomarkers, preclinical toxicology testing paradigms, and practical applications Discusses rare diseases Discusses "What-Why-When-How" highlighting different considerations based upon product attributes. Includes special considerations for rare diseases About the Editors Joy A. Cavagnaro is an internationally recognized expert in preclinical development and regulatory strategy with an emphasis on genetic medicines.. Her 40-year career spans academia, government (FDA), and the CRO and biotech industries. She was awarded the 2019 Arnold J Lehman Award from the Society of Toxicology for introducing the concept of science-based, case-by-case approach to preclinical safety evaluation, which became the foundation of ICH S6. She currently serves on scientific advisory boards for advocacy groups and companies and consults and lectures in the area of preclinical development of novel therapies. Mary Ellen Cosenza is a regulatory toxicology consultant with over 30 years of senior leadership experience in the biopharmaceutical industry in the U.S., Europe, and emerging markets. She has held leadership position in both the American College of Toxicology (ACT) and the International Union of Toxicology (IUTOX) and is also an adjunct assistant professor at the University of Southern California where she teaches graduate-level courses in toxicology and regulation of biologics.
Lonely Planet S Best In Travel 2020
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Author : Lonely Planet
language : en
Publisher: Lonely Planet
Release Date : 2019-10-22
Lonely Planet S Best In Travel 2020 written by Lonely Planet and has been published by Lonely Planet this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-10-22 with Travel categories.
This annual bestseller ranks the hottest countries, regions and cities for 2020, and reveals how well-planned, sustainable travel can be a force for good. Drawing on the knowledge and passion of Lonely Planet's staff, authors and online community, we present a year's worth of inspiration to take you out of the ordinary and into the unforgettable.
A Respectable Trade
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Author : Philippa Gregory
language : en
Publisher: Simon and Schuster
Release Date : 2007-02
A Respectable Trade written by Philippa Gregory and has been published by Simon and Schuster this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-02 with Fiction categories.
Entering into an arranged marriage with an aspiring merchant in 1787 Bristol, Frances Scott is discouraged by her slavery-dependent lifestyle and unexpectedly falls for African slave and former Yoruba priest Mehuru. By the author of The Other Boleyn Girl. Reprint. 75,000 first printing.
Pulping The South
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Author : Ricardo Carriere
language : en
Publisher: Zed Books
Release Date : 1996-08-15
Pulping The South written by Ricardo Carriere and has been published by Zed Books this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996-08-15 with Business & Economics categories.
The expansion of the pulp and paper industry is one of the most important causes of land and water conflicts in the South. This book examines the threat to livelihood, soil and biodiversity generated by large-scale pulpwood plantations in the South.
The Road To Wigan Pier
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Author : George Orwell
language : en
Publisher: Oxford University Press, USA
Release Date : 2021-01-07
The Road To Wigan Pier written by George Orwell and has been published by Oxford University Press, USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-01-07 with Literary Criticism categories.
The Road to Wigan Pier is Orwell's 1937 study of poverty and working-class life in northern England.
Altered States English Edition
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Author : Paddy Chayefsky
language : en
Publisher: BookRix
Release Date : 2022-01-19
Altered States English Edition written by Paddy Chayefsky and has been published by BookRix this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-19 with Fiction categories.
Edward Jessup, a young psycho-physiologist, experiments with different states of consciousness, obsessed with an addiction to truth and knowledge. He injects himself with psychedelic drugs, lies locked in an isolation tank and experiences all the stages of pre-human consciousness until finally terrible changes take place with him: Jessup also physically transforms into a pre-human being. His thirst for knowledge drives him into ever new, increasingly irreversible transformations. Only the horror when his body begins to dissolve into pure energy brings him back to human bonds... Paddy Chayefsky (January 29, 1923 – August 1, 1981), one of the most important US dramatists, wrote a breath-taking, equally philosophical shocker with his debut novel. In 1980, British director Ken Russell adapted the novel based on Paddy Chayefsky's screenplay - starring: William Hurt, Blair Brown and Drew Barrymore.
The Land Within
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Author : Pedro García Hierro
language : en
Publisher: IWGIA
Release Date : 2005
The Land Within written by Pedro García Hierro and has been published by IWGIA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with Science categories.
By describing the fabric of relationships indigenous peoples weave with their environment, The Land Within attempts to define a more precise notion of indigenous territoriality. A large part of the work of titling the South American indigenous territories may now be completed but this book aims to demonstrate that, in addition to management, these territories involve many other complex aspects that must not be overlooked if the risk of losing these areas to settlers or extraction companies is to be avoided. Alexandre Surralls holds a doctorate in anthropology from the School for Higher Studies in Social Sciences and is a researcher on the staff of the National Centre for Scientific Research. Pedro Garca Hierro is a lawyer from Madrid Complutense University and the Pontifical Catholic University of Peru. He has worked with various indigenous organizations, on issues related to the identification and development of collective rights and the promotion of intercultural democratic reforms.
Worldwide Multilingual Phrase Book
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Author : Eric Dondero R.
language : en
Publisher:
Release Date : 2002-02-01
Worldwide Multilingual Phrase Book written by Eric Dondero R. and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-02-01 with English language categories.
A Portuguese English Dictionary
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Author : James Lumpkin Taylor
language : en
Publisher: Stanford University Press
Release Date : 1958
A Portuguese English Dictionary written by James Lumpkin Taylor and has been published by Stanford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1958 with Foreign Language Study categories.
Veja
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Author :
language : pt-BR
Publisher:
Release Date : 2003
Veja written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003 with Brazil categories.