Water And Biomolecules
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Water And Biomolecules
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Author : Kunihiro Kuwajima
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-03-18
Water And Biomolecules written by Kunihiro Kuwajima and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-03-18 with Science categories.
Life is produced by the interplay of water and biomolecules. This book deals with the physicochemical aspects of such life phenomena produced by water and biomolecules, and addresses topics including "Protein Dynamics and Functions", "Protein and DNA Folding", and "Protein Amyloidosis". All sections have been written by internationally recognized front-line researchers. The idea for this book was born at the 5th International Symposium "Water and Biomolecules", held in Nara city, Japan, in 2008.
Dynamics Of Water Interacting With Biomolecules
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Author : Carien C. M. Groot
language : en
Publisher:
Release Date : 2017
Dynamics Of Water Interacting With Biomolecules written by Carien C. M. Groot and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017 with categories.
Life as we know it takes place in liquid water. This water is not merely a passive solvent, but plays an active role in many biological processes. Understanding the subtle interplay between water and biomolecules is therefore crucial for understanding the mechanics and chemistry of life. In this thesis, we present a series of spectroscopic experiments that elucidate the hydrogen-bond structure and dynamics of water molecules in solutions of different biologically relevant molecules. In particular, we studied solutions of sugars, globular proteins, and antifreeze glycoproteins, and water molecules confined in triglyceride oils. As a tool, we used vibrational pump-probe spectroscopy. This technique uses a short, intense infrared pump pulse to excite molecular vibrations that we can follow over time by monitoring the infrared absorption of a second, weaker probe pulse. The thus obtained time-resolved spectra provide information on for example the hydrogen-bond dynamics and the reorientation dynamics of water, which in turn allows insight in the molecular mechanism of different biological processes.
Neutron Scattering Studies Of Water In Biomolecules And Biomaterials
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Author : Lok Chan
language : en
Publisher:
Release Date : 2012
Neutron Scattering Studies Of Water In Biomolecules And Biomaterials written by Lok Chan and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with categories.
It is increasingly important to identify the nature of the interfacial water in biology in order to explain how biological functions and systems work. It is not simply a matter of which biomolecules are present in a cell, but also of how these biomolecules interact with one another. This body of work uses neutron scattering techniques to explain the nature of the vibrational dynamics of water interacting with biomolecules and systems that mimic the biological molecular crowding environment of a cell. Recent work in science has seen the synthesis of periodic mesoporous organosilicas with organic groups attached. In the first paper in this thesis, the use of one of these materials is highlighted to look at confined water, equivalent to the water found in a crowded cellular environment. Here it is shown that the properties of the water within the pores and water molecules around the surface were shown to be different and then identified as interfacial and bulk water respectively. In order to develop the investigation of interfacial water with biological matter, it seemed appropriate to start with the most basic molecules, amino acids. The second paper presents a complete survey of the 20 biologically important amino acids using one of the world's highest resolution neutron scattering spectrometer (TOSCA at ISIS, Rutherford Appleton Laboratory). Computer simulation of the experimental work through molecular dynamics, allows many vibrational modes to be assigned for the first time and correlated with the broader vibrational peaks previously observed for proteins. Comparison of the dry states with the hydrated states of amino acids, gives some insight into the sites within the amino acid side chains where water molecules are likely to bind. For serine this is the hydroxyl group in the side chain. The third paper focuses on IINS data of serine in more detail and discusses several low energy vibrational modes that have been assigned and for the first time, shows how the presence of water molecules changes the dynamic behaviour of librational and torsional modes differently. The combination of these studies allows a clearer picture of how water in biology interacts with biomolecules and of the importance of water to our existence.
Water And Biological Macromolecules
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Author : Westhof
language : en
Publisher: CRC Press
Release Date : 1993-08-16
Water And Biological Macromolecules written by Westhof and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993-08-16 with Science categories.
Water and Biological Macromolecules presents an excellent description of the structural aspects of water molecules around biological macromolecules. Topics discussed include the properties of water in solid and liquid states; proteins, nucleic acids, polysaccharides, and lipids; and theoretical approaches for understanding the macroscopic observations and integrating microscopic descriptions. The nature and roles of hydration forces in macromolecular complexation and cell-cell interactions are explained, in addition to phenomena such as entropy-enthalpy compensation and the thermodynamic treatment of water bridging. Water and Biological Macromolecules will be a valuable reference for biophysicists, biochemists, and macromolecular biologists.
Determination Of Liquid Water Structure
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Author : E. Clementi
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Determination Of Liquid Water Structure written by E. Clementi and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
One should distinguish between coordination numbers and hydration numbers. Following Bockris
Biological Water
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Author : Gertz I. Likhtenshtein
language : en
Publisher: Springer Nature
Release Date : 2021-10-21
Biological Water written by Gertz I. Likhtenshtein and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-10-21 with Science categories.
This book embraces all physiochemical aspects of the structure and molecular dynamics of water, focusing on its role in biological objects, e.g. living cells and tissue, and in the formation of functionally active structures of biological molecules and their ensembles. Water is the single most abundant chemical found in all living things. It offers a detailed look into the latest modern physical methods for studying the molecular structure and dynamics of the water and provides a critical analysis of the existing literature data on the properties of water in biological objects. Water as a chemical reagent and as a medium for the formation of conditions for enzymatic catalysis is a core focus of this book. Although well suited for active researchers, the book as a whole, as well as each chapter on its own, can be used as fundamental reference material for graduate and undergraduate students throughout chemistry, physics, biophysics and biomedicine.
Molecular Dynamics Studies Of Water And Biomolecules
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Author : Pekka Mark
language : en
Publisher:
Release Date : 2002
Molecular Dynamics Studies Of Water And Biomolecules written by Pekka Mark and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with categories.
Water And Life
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Author : Ruth M. Lynden-Bell
language : en
Publisher: CRC Press
Release Date : 2010-05-21
Water And Life written by Ruth M. Lynden-Bell and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-05-21 with Medical categories.
Reflecting a rich technical and interdisciplinary exchange of ideas, Water and Life: The Unique Properties of H20 focuses on the properties of water and its interaction with life. The book develops a variety of approaches that help to illuminate ways in which to address deeper questions with respect to the nature of the universe and our place withi
Biomolecules
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Author : S.R. Mishra
language : en
Publisher: Discovery Publishing House
Release Date : 2003
Biomolecules written by S.R. Mishra and has been published by Discovery Publishing House this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003 with Science categories.
Contents: Biomolecules, Atoms and Molecules, Water, The Magic of Carbon, The Cell, The Catalysts of Life, Bionergetics, Carbohydrates, Protein Structure and Function, Amino Acid, Individual Amino Acid Metabolism, Lipids.
Determination Of Liquid Water Structure Coordination Numbers For Ions And Solvation For Biological Molecules
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Author : Enrico Clementi
language : en
Publisher: Springer
Release Date : 1976
Determination Of Liquid Water Structure Coordination Numbers For Ions And Solvation For Biological Molecules written by Enrico Clementi and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 1976 with Biomolecules categories.