A Handbook Of Derivatives For Mass Spectrometry
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A Handbook Of Derivatives For Mass Spectrometry
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Author : Vladimir Zaikin
language : en
Publisher: IM Publications
Release Date : 2009
A Handbook Of Derivatives For Mass Spectrometry written by Vladimir Zaikin and has been published by IM Publications this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with Derivatization categories.
Chemical derivatisation of functional groups has proved popular since the beginning of organic mass spectrometry as a means to enhance the stability and volatility of the analytes as well as facilitating structure elucidation. This book provides comprehensive information on the wide range of derivatisation methods. Each chapter looks at a particular area of derivatisation and includes extensive references to the literature for further research where necessary. There are nearly 1800 references, which, as well as full bibliographic information, include chapter/paper titles where appropriate and Digital Object Identifiers (DOIs) to allow easy retrieval of the online version of the referenced publication. The emergence of atmospheric pressure ionisation and other soft ionisation techniques has not diminished the interest in such chemical techniques, as witnessed by the many chemical tags used in quantitative proteomics (Chapter 9). The last two chapters, a substantial part of the book, deal with derivatisation for use with soft ionisation of both small and large molecules. Chapters Silylation Acylation Alkylation (Arylation) Cyclic derivatives Monofunctional compounds Polyfunctional compounds On-line derivatisation/degradation Soft ionisation—small molecules Soft ionisation—large molecules
Mass Spectrometry Handbook
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Author : Mike S. Lee
language : en
Publisher: John Wiley & Sons
Release Date : 2012-04-16
Mass Spectrometry Handbook written by Mike S. Lee and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-04-16 with Science categories.
Due to its enormous sensitivity and ease of use, mass spectrometry has grown into the analytical tool of choice in most industries and areas of research. This unique reference provides an extensive library of methods used in mass spectrometry, covering applications of mass spectrometry in fields as diverse as drug discovery, environmental science, forensic science, clinical analysis, polymers, oil composition, doping, cellular research, semiconductor, ceramics, metals and alloys, and homeland security. The book provides the reader with a protocol for the technique described (including sampling methods) and explains why to use a particular method and not others. Essential for MS specialists working in industrial, environmental, and clinical fields.
Metabolomics Metabonomics And Metabolite Profiling
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Author : William J. Griffiths
language : en
Publisher: Royal Society of Chemistry
Release Date : 2008
Metabolomics Metabonomics And Metabolite Profiling written by William J. Griffiths and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with Medical categories.
In this comprehensive resource the Editor draws together experts from the field and provides an insightful introduction into the technology and methodology.
Mass Spectrometry
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Author : Jürgen H Gross
language : en
Publisher: Springer
Release Date : 2011-01-19
Mass Spectrometry written by Jürgen H Gross and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-01-19 with Science categories.
This book offers a balanced mixture of practice-oriented information and theoretical background as well as numerous references, clear illustrations, and useful data tables. Problems and solutions are accessible via a special website. This new edition has been completely revised and extended; it now includes three new chapters on tandem mass spectrometry, interfaces for sampling at atmospheric pressure, and inorganic mass spectrometry.
Handbook Of Gc Ms
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Author : Hans-Joachim Hubschmann
language : en
Publisher: John Wiley & Sons
Release Date : 2025-03-06
Handbook Of Gc Ms written by Hans-Joachim Hubschmann and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-03-06 with Science categories.
Essential handbook for all analytical scientists and laboratories using GC-MS, covering both the fundamental and practical aspects of this analytical technique From essentials to applications, Handbook of GC-MS:Fundamentals and Applications is a comprehensive reference and training compendium on the popular and evolving technique of GC-MS (gas chromatography/mass spectrometry), guiding readers through the most used sample preparation methods for GC-MS and method development, with many practical indications supporting the design of optimized analyses, and providing practical approaches to data processing, compound identification, and quantification. The text details both a solid background and principles of operation, as well as a broad range of current real-life examples taken from laboratories in environmental, food, pharmaceutical, and forensic analysis. It also features a glossary of more than 300 terms, and a comprehensive substance index that facilitates finding a specific application. This timely Fourth Edition covers the latest developments in automated sample preparation techniques and instrumentation, also with the focus on Green Analytical Chemistry. This comprehensive handbook presents GC-MS applications in various fields, with coverage of the well-known QuEChERS pesticide extraction, solid phase extraction and solid phase microextraction, static and dynamic headspace analysis, liquid/liquid extraction, outgassing, and thermal desorption, including pyrolysis. Single and triple quadrupole, Orbitrap, time-of-flight, magnetic sector, ion mobility and isotope ratio MS are discussed with their advantages and limitations. Sample topics covered in Handbook of GC-MS: Fundamentals and Applications include: Sample inlet systems for hot needle, liquid band injection with large volume and LC-GC application, carrier gas saving, choice of columns, septa and injection port liners Optimization of the GC method with carrier gas flow, effect of oven temperature ramp rates, fast GC, and multi-dimensional gas chromatography Ionization processes, electron and chemical ionization, resolution power in mass spectrometry, reading and interpreting mass spectra Extraction of mass spectra, manual spectrum subtraction, deconvolution of mass spectra, retention index, and library search of mass spectra Typical mass spectra of common analyte groups like pesticides, persistent organic pollutants, drugs; explosives; and of frequently occurring impurities Quantification using external and internal standards and standard addition methods. Determination of the limits of detection and quantitation. Applications covering food, water, flavor and fragrance, metabolomics, forensic and material analysis The Handbook of GC-MS: Fundamentals and Applications is an essential reference for the daily GC-MS practice and application of new methods. It serves as an excellent introduction for newcomers as well as an educational resource about this analytical technique. Analytical chemists, chromatographers, environmental chemists, food chemists, and pharmaceutical chemists will find it of high practical use.
Handbook Of Lc Ms Bioanalysis
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Author : Wenkui Li
language : en
Publisher: John Wiley & Sons
Release Date : 2013-09-03
Handbook Of Lc Ms Bioanalysis written by Wenkui Li and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-09-03 with Science categories.
Consolidates the information LC-MS bioanalytical scientists need to analyze small molecules and macromolecules The field of bioanalysis has advanced rapidly, propelled by new approaches for developing bioanalytical methods, new liquid chromatographic (LC) techniques, and new mass spectrometric (MS) instruments. Moreover, there are a host of guidelines and regulations designed to ensure the quality of bioanalytical results. Presenting the best practices, experimental protocols, and the latest understanding of regulations, this book offers a comprehensive review of LC-MS bioanalysis of small molecules and macromolecules. It not only addresses the needs of bioanalytical scientists working on routine projects, but also explores advanced and emerging technologies such as high-resolution mass spectrometry and dried blood spot microsampling. Handbook of LC-MS Bioanalysis features contributions from an international team of leading bioanalytical scientists. Their contributions reflect a review of the latest findings, practices, and regulations as well as their own firsthand analytical laboratory experience. The book thoroughly examines: Fundamentals of LC-MS bioanalysis in drug discovery, drug development, and therapeutic drug monitoring The current understanding of regulations governing LC-MS bioanalysis Best practices and detailed technical instructions for LC-MS bioanalysis method development, validation, and stability assessment of analyte(s) of interest Experimental guidelines and protocols for quantitative LC-MS bioanalysis of challenging molecules, including pro-drugs, acyl glucuronides, N-oxides, reactive compounds, and photosensitive and autooxidative compounds With its focus on current bioanalytical practice, Handbook of LC-MS Bioanalysis enables bioanalytical scientists to develop and validate robust LC-MS assay methods, all in compliance with current regulations and standards.
Mass Spectrometry
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Author : A. M. Lawson
language : en
Publisher: Walter de Gruyter GmbH & Co KG
Release Date : 2021-03-22
Mass Spectrometry written by A. M. Lawson and has been published by Walter de Gruyter GmbH & Co KG this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-22 with Science categories.
No detailed description available for "Mass Spectrometry".
Liquid Chromatography
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Author : Salvatore Fanali
language : en
Publisher: Elsevier
Release Date : 2017-06-23
Liquid Chromatography written by Salvatore Fanali and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-06-23 with Science categories.
Liquid Chromatography: Applications, Second Edition,is a single source of authoritative information on all aspects of the practice of modern liquid chromatography. It gives those working in both academia and industry the opportunity to learn, refresh, and deepen their knowledge of the wide variety of applications in the field. In the years since the first edition was published, thousands of papers have been released on new achievements in liquid chromatography, including the development of new stationary phases, improvement of instrumentation, development of theory, and new applications in biomedicine, metabolomics, proteomics, foodomics, pharmaceuticals, and more. This second edition addresses these new developments with updated chapters from the most expert researchers in the field. - Emphasizes the integration of chromatographic methods and sample preparation - Explains how liquid chromatography is used in different industrial sectors - Covers the most interesting and valuable applications in different fields, e.g., proteomic, metabolomics, foodomics, pollutants and contaminants, and drug analysis (forensic, toxicological, pharmaceutical, biomedical) - Includes references and tables with commonly used data to facilitate research, practical work, comparison of results, and decision-making
Introduction To Mass Spectrometry
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Author : J. Throck Watson
language : en
Publisher: John Wiley & Sons
Release Date : 2007-11-12
Introduction To Mass Spectrometry written by J. Throck Watson and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-11-12 with Science categories.
Completely revised and updated, this text provides an easy-to-read guide to the concept of mass spectrometry and demonstrates its potential and limitations. Written by internationally recognised experts and utilising "real life" examples of analyses and applications, the book presents real cases of qualitative and quantitative applications of mass spectrometry. Unlike other mass spectrometry texts, this comprehensive reference provides systematic descriptions of the various types of mass analysers and ionisation, along with corresponding strategies for interpretation of data. The book concludes with a comprehensive 3000 references. This multi-disciplined text covers the fundamentals as well as recent advance in this topic, providing need-to-know information for researchers in many disciplines including pharmaceutical, environmental and biomedical analysis who are utilizing mass spectrometry
Encyclopedia Of Chromatography
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Author : Jack Cazes
language : en
Publisher: CRC Press
Release Date : 2005
Encyclopedia Of Chromatography written by Jack Cazes and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with Science categories.
A convenient source of information for workers in analytical chemistry, experimental biology, physics, and engineering, this Second Edition stands as a quick reference source and clear guide to specific chromatographic techniques and principles-providing a basic introduction to the science and technology of the method, as well as additional references on the theory and methodology for analysis of specific chemicals and applications in a range of industries.