A Manual For Biomaterials Scaffold Fabrication Technology

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A Manual For Biomaterials Scaffold Fabrication Technology

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Author : Gilson Khang
language : en
Publisher: World Scientific Publishing Company
Release Date : 2007-07-03

A Manual For Biomaterials Scaffold Fabrication Technology written by Gilson Khang and has been published by World Scientific Publishing Company this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-07-03 with Science categories.

Tissue engineering has been recognized as offering an alternative technique to whole-organ and tissue transplantation for diseased, failed, or malfunctioned organs. To reconstruct a new tissue via tissue engineering, the following triad components are needed: (1) cells which are harvested and dissociated from the donor tissue; (2) biomaterials as scaffold substrates in which cells are attached and cultured, resulting in implantation at the desired site of the functioning tissue; and (3) growth factors which promote and/or prevent cell adhesion, proliferation, migration, and differentiation. Of these three key components, scaffolds play a critical role in tissue engineering. This timely book focuses on the preparation and characterization of scaffold biomaterials for the application of tissue-engineered scaffolds. More importantly, it serves as an experimental guidebook on the standardization of the fabrication process and characterization of scaffolding technology.

Handbook Of Intelligent Scaffolds For Tissue Engineering And Regenerative Medicine

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Author : Gilson Khang
language : en
Publisher: CRC Press
Release Date : 2017-06-26

Handbook Of Intelligent Scaffolds For Tissue Engineering And Regenerative Medicine written by Gilson Khang and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-06-26 with Medical categories.

Millions of patients suffer from end-stage organ failure or tissue loss annually, and the only solution might be organ and/or tissue transplantation. To avoid poor biocompatibility–related problems and donor organ shortage, however, around 20 years ago a new, hybridized method combining cells and biomaterials was introduced as an alternative to whole-organ and tissue transplantation for diseased, failing, or malfunctioning organs—regenerative medicine and tissue engineering. This handbook focuses on all aspects of intelligent scaffolds, from basic science to industry to clinical applications. Its 10 parts, illustrated throughout with excellent figures, cover stem cell engineering research, drug delivery systems, nanomaterials and nanodevices, and novel and natural biomaterials. The book can be used by advanced undergraduate- and graduate-level students of stem cell and tissue engineering and researchers in macromolecular science, ceramics, metals for biomaterials, nanotechnology, chemistry, biology, and medicine, especially those interested in tissue engineering, stem cell engineering, and regenerative medicine.

Introduction To Biomaterials

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Author : Donglu Shi
language : en
Publisher: World Scientific Publishing Company Incorporated
Release Date : 2006

Introduction To Biomaterials written by Donglu Shi and has been published by World Scientific Publishing Company Incorporated this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with Technology & Engineering categories.

1. Introduction to bioceramics. 1.1. Bioactive materials. 1.2. References -- 2. Bioactive ceramics : structure, synthesis, and mechanical properties. 2.1. Structure of hydroxyapatite. 2.2. Synthesis of hydroxyapatite powder. 2.3. Mechanical properties of hydroxyapatite. 2.4. Other bioceramics. 2.5. References. 2.6. Problems -- 3. Bioceramic processing. 3.1. Fabrication and mechanical properties of porous bioceramics. 3.2. Coating of bioceramic thick films on bio-inert porous subs. 3.3. Coating on dense substrates. 3.4. Hydroxyapatite coatings for non-hard tissue applications. 3.5. Composites. 3.6. Summary. 3.7. References. 3.8. Problems -- 4. Coating of hydroxyapatite onto inner pore surfaces of the reticulated alumina. 4.1. Hydroxyapatite coating methods and characterization. 4.2. Adhesion of hydroxyapatite film on alumina substrate. 4.3. References. 4.4. Problems -- 5. Properties and characterization of biomaterials. 5.1. Characterization of ceramics. 5.2. Bioactive properties and hard tissue prosthetics. 5.3. Measurements of growth and dissolution of hydroxyapatite ceramics. 5.4. In vitro test conducted in this reasearch. 5.5. Mechanical properties. 5.6. References. 5.7. Problems -- 6. Bioactivity of hydroxyapatite. 6.1. General aspects. 6.2. In vitro testing materials and preparation. 6.3. Characterization of immersion solution. 6.4. Morphology of the reacted surfaces. 6.5. References. 6.6. Problems -- 7. Hydroxyapatite deposition mechanisms. 7.1. Material synthesis and hydroxyapatite coating. 7.2. Mechanisms of bioactivity. 7.3. References. 7.4. Problems -- 8. Biomedical metallic materials. 8.1. Microstructures and processing. 8.2. Corrosion resistance of metals. 8.3. Biological tolerance of metal. 8.4. Stainless steel. 8.5. Cobalt-based alloys. 8.6. Titanium and its alloys. 8.7. TiNi shape memory alloy. 8.8. Summary. 8.9. References. 8.10. Problems -- 9. Polymer basics. 9.1. Classification of polymers. 9.2. Characteristics of polymer. 9.3. Synthesis of polymers. 9.4. References. 9.5. Problems -- 10. Naturally occurring polymer biomaterials. 10.1. General introduction to proteins. 10.2. Collagen. 10.3. Alginate. 10.4. Chitin and chitosan. 10.5. References. 10.6. Problems -- 11. Synthetic non-biodegradable polymers. 11.1. Polyethylene. 11.2. Poly (methyl methacrylate). 11.3. Polyester. 11.4. Polycarbonate. 11.5. Polyamides. 11.6. Polyurethane. 11.7. Pofysulfones. 11.8. Poly (ether ether ketone). 11.9. References. 11.10. Problems -- 12. Synthetic biodegradable polymers. 12.1. Aliphatic polyester. 12.2. Poly (propylene fumarate). 12.3. Polyamino acid. 12.4. References. 12.5. Problems -- 13. Polymer matrix composite biomaterials. 13.1. Fiber reinforced composites. 13.2. Filler reinforced composites. 13.3. Methods to improve the interfacial bonding between phases in composites. 13.4. References. 13.5. Problems -- 14. Biomaterials for tissue engineering. 14.1. General aspects of biomaterials used for tissue engineering. 14.2. Representative biomaterials used for tissue engineering. 14.3. Biomaterial constructs for tissue engineering : scaffolds. 14.4. References. 14.5. Problems -- 15. Cells and biomolecules for tissue engineering. 15.1. Cells for tissue engineering. 15.2. Growth factor delivery in tissue engineering. 15.3. Regulatory matrix proteins. 15.4. References. 15.5. Problems -- 16. Transport and vascularization in tissue engineering. 16.1. Transport in engineered tissue. 16.2. Vascularization. 16.3. References. 16.4. Problems -- 17. Host response to tissue engineered grafts. 17.1. The foreign body response to synthetic components. 17.2. Response to biological components. 17.3. References. 17.4. Problems -- 18. Other important issues and future challenges in tissue engineering. 18.1. Organ replacement and regeneration. 18.2. Organotypic and histiotypic models. 18.3. Mechanotransduction. 18.4. Future challenges. 18.5. References. 18.6. Problems

A Manual For Primary Human Cell Culture

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Author : Kee Woei Ng
language : en
Publisher: World Scientific
Release Date : 2010

A Manual For Primary Human Cell Culture written by Kee Woei Ng and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010 with Medical categories.

This manual is designed to serve as a practical guide to primary human cell culture, which is integral in both academic and industrial biotechnology research. As in the first edition, the content of the manual is not exhaustive, but rather contains selected protocols for specific cell types from major tissue groupings in the body. This improved second edition also includes a new section on stem cells and additional material on transfection. It should serve as a foundation for individual researchers to experiment, explore, and establish niche protocols for their specific needs. With its compact physical format that makes it portable and flexible for usage in a laboratory setting, the manual will be a useful guide for all beginners in primary human cell culture work.

Biomaterials Fabrication And Processing Handbook

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Author : Paul K. Chu
language : en
Publisher: CRC Press
Release Date : 2008-03-27

Biomaterials Fabrication And Processing Handbook written by Paul K. Chu and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-03-27 with Medical categories.

This volume focuses on a variety of production and processing aspects of the latest biomaterials. It discusses how scaffolds are used in tissue engineering and describes common implant materials, such as hard tissue, blood contacting, and soft tissue. The book also examines the important role nanotechnology plays in the preparation of drugs, protein delivery, tissue engineering, cardiovascular biomaterials, hard tissue replacements, biosensors, and bio-MEMS. With contributions from renowned international experts and extensive reference lists in each chapter, this book provides detailed, practical information to produce biomaterials and employ them in biomedicine.

A Manual For Differentiation Of Bone Marrow Derived Stem Cells To Specific Cell Types

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Author : Kee Woei Ng
language : en
Publisher: World Scientific Publishing Company
Release Date : 2014-02-11

A Manual For Differentiation Of Bone Marrow Derived Stem Cells To Specific Cell Types written by Kee Woei Ng and has been published by World Scientific Publishing Company this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-02-11 with Technology & Engineering categories.

This is the first experimental protocol book that covers the differentiation of bone marrow-derived stem cells (BMSCs) into specific cell types, targeted at the undergraduate and graduate student level. The 19 chapters deal with the differentiation methods using small molecules, cytokines and polymeric scaffolds.BMSCs are pluripotential in that they not only act as myelo-regenerative and supportive cells, but can also differentiate into almost any kind of cells in our body. In addition, when implanted in vivo, they could help repair multiple tissues such as blood vessels, heart, liver and so on.For the differentiation of BMSCs, many methods have been introduced to adjust their microenvironment (chemical and physical cues), including chemical induction methods using large or small molecules and pellet culture; mechanical stimulation induction methods using cyclic mechano-transduction or ultrasonication; cytokine-released method using scaffolds; and so on.

A Manual For Laboratory Animal Management

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Author : Jonathan David Ward
language : en
Publisher: World Scientific
Release Date : 2008

A Manual For Laboratory Animal Management written by Jonathan David Ward and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with Science categories.

Laboratory animal research remains a very important part of basic research and drug development. This book rectifies the problem by providing animal researchers and technicians with the essentials for conducting their work in the laboratory, offering detailed protocols and information that can be referred to on a daily basis.

Biomedical Engineering Frontier Research And Converging Technologies

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Author : Hanjoong Jo
language : en
Publisher: Springer
Release Date : 2015-07-23

Biomedical Engineering Frontier Research And Converging Technologies written by Hanjoong Jo and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-07-23 with Technology & Engineering categories.

This book provides readers with an integrative overview of the latest research and developments in the broad field of biomedical engineering. Each of the chapters offers a timely review written by leading biomedical engineers and aims at showing how the convergence of scientific and engineering fields with medicine has created a new basis for practically solving problems concerning human health, wellbeing and disease. While some of the latest frontiers of biomedicine, such as neuroscience and regenerative medicine, are becoming increasingly dependent on new ideas and tools from other disciplines, the paradigm shift caused by technological innovations in the fields of information science, nanotechnology, and robotics is opening new opportunities in healthcare, besides dramatically changing the ways we actually practice science. At the same time, a new generation of engineers, fluent in many different scientific “languages,” is creating entirely new fields of research that approach the “old” questions from a new and holistic angle. The book reports on the scientific revolutions in the field of biomedicine by describing the latest technologies and findings developed at the interface between science and engineering. It addresses students, fellows, and faculty and industry investigators searching for new challenges in the broad biomedical engineering fields.

Handbook Of Intelligent Scaffold For Tissue Engineering And Regenerative Medicine

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Author :
language : en
Publisher: CRC Press
Release Date : 2012-02-17

Handbook Of Intelligent Scaffold For Tissue Engineering And Regenerative Medicine written by and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-02-17 with Medical categories.

Providing detailed knowledge about fullerene nanowhiskers and the related low-dimensional fullerene nanomaterials, this book introduces tubular nanofibers made of fullerenes, "fullerene nanotubes," as well as the single crystalline thin film made of C60, called "fullerene nanosheet." It is the first publication featuring the fullerene nanowhiskers made of C60, C70, and C60 derivatives and so forth. It demonstrates the synthetic method (liquid–liquid interfacial precipitation method) and the physical and chemical properties such as electrical, mechanical, optical, magnetic, thermodynamic, and surface properties for the fullerene nanowhiskers, including their electronic device application.

Cartilage From Biology To Biofabrication

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Author : Mohamadreza Baghaban Eslaminejad
language : en
Publisher: Springer Nature
Release Date : 2023-07-11

Cartilage From Biology To Biofabrication written by Mohamadreza Baghaban Eslaminejad and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-07-11 with Science categories.

This book provides a comprehensive overview of cartilage structure, functions, and approaches for the regeneration of cartilage tissue. It reviews multiple signaling pathways that are involved in the growth and repair of cartilage tissue. The initial chapter of the book examines the etiology, diagnosis, and pathological features of various cartilage diseases. Subsequently, the book presents recent advances in biomaterial sciences, regenerative medicine, and fabrication technology for cartilage regeneration. It discusses hydrogels as a promising scaffold for cartilage tissue engineering, focusing on recapitulating microenvironments present during development or in adult tissue to induce the formation of cartilaginous constructs with biochemical and mechanical properties of native tissue. Lastly, it covers the applications of 3 D printing techniques for the fabrication of scaffolds for cartilage tissue regeneration for the production of biological implants capable of treating a range of conditions.