A Mutation Selection Model With Recombination For General Genotypes
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A Mutation Selection Model With Recombination For General Genotypes
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Author : Steven Neil Evans
language : en
Publisher: American Mathematical Soc.
Release Date : 2013-02-26
A Mutation Selection Model With Recombination For General Genotypes written by Steven Neil Evans and has been published by American Mathematical Soc. this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-02-26 with Mathematics categories.
The authors investigate a continuous time, probability measure-valued dynamical system that describes the process of mutation-selection balance in a context where the population is infinite, there may be infinitely many loci, and there are weak assumptions on selective costs. Their model arises when they incorporate very general recombination mechanisms into an earlier model of mutation and selection presented by Steinsaltz, Evans and Wachter in 2005 and take the relative strength of mutation and selection to be sufficiently small. The resulting dynamical system is a flow of measures on the space of loci. Each such measure is the intensity measure of a Poisson random measure on the space of loci: the points of a realization of the random measure record the set of loci at which the genotype of a uniformly chosen individual differs from a reference wild type due to an accumulation of ancestral mutations. The authors' motivation for working in such a general setting is to provide a basis for understanding mutation-driven changes in age-specific demographic schedules that arise from the complex interaction of many genes, and hence to develop a framework for understanding the evolution of aging.
A Mutation Selection Model With Recombination For General Genotypes
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Author : Steven Neil Evans
language : en
Publisher:
Release Date : 2013
A Mutation Selection Model With Recombination For General Genotypes written by Steven Neil Evans and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013 with Evolutionary genetics categories.
We investigate a continuous time, probability measure-valued dynamical system that describes the process of mutation-selection balance in a context where the population is infinite, there may be infinitely many loci, and there are weak assumptions on selective costs. Our model arises when we incorporate very general recombination mechanisms into an earlier model of mutation and selection presented by Steinsaltz, Evans and Wachter in 2005 and take the relative strength of mutation and selection to be sufficiently small. The resulting dynamical system is dynamical system a flow of measures on the space of loci. Each such measure is the intensity measure of a Poisson random measure on the space of loci: intensity measure the points of a realization of the random measure record the set of loci at which the genotype of a uniformly chosen individual differs from a reference wild type due to an accumulation of ancestral mutations. Our motivation for working in such a general setting is to provide a basis for understanding mutation-driven changes in age-specific demographic schedules that arise from the complex interaction of many genes, and hence to develop a framework for understanding the evolution of aging. We establish the existence and uniqueness of the dynamical system, provide conditions for the existence and stability of equilibrium states, and prove that our continuous-time dynamical system is the limit of a sequence of discrete-time infinite population mutation-selection-recombination models in the standard asymptotic regime where selection and mutation are weak relative to recombination and both scale at the same infinitesimal rate in the limit.
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Author :
language : en
Publisher: World Scientific
Release Date :
written by and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.
Kuznetsov S Trace Formula And The Hecke Eigenvalues Of Maass Forms
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Author : Andrew Knightly
language : en
Publisher: American Mathematical Soc.
Release Date : 2013-06-28
Kuznetsov S Trace Formula And The Hecke Eigenvalues Of Maass Forms written by Andrew Knightly and has been published by American Mathematical Soc. this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-28 with Mathematics categories.
The authors give an adelic treatment of the Kuznetsov trace formula as a relative trace formula on $\operatorname{GL}(2)$ over $\mathbf{Q}$. The result is a variant which incorporates a Hecke eigenvalue in addition to two Fourier coefficients on the spectral side. The authors include a proof of a Weil bound for the generalized twisted Kloosterman sums which arise on the geometric side. As an application, they show that the Hecke eigenvalues of Maass forms at a fixed prime, when weighted as in the Kuznetsov formula, become equidistributed relative to the Sato-Tate measure in the limit as the level goes to infinity.
On Some Aspects Of Oscillation Theory And Geometry
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Author : Bruno Bianchini
language : en
Publisher: American Mathematical Soc.
Release Date : 2013-08-23
On Some Aspects Of Oscillation Theory And Geometry written by Bruno Bianchini and has been published by American Mathematical Soc. this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-08-23 with Mathematics categories.
The aim of this paper is to analyze some of the relationships between oscillation theory for linear ordinary differential equations on the real line (shortly, ODE) and the geometry of complete Riemannian manifolds. With this motivation the authors prove some new results in both directions, ranging from oscillation and nonoscillation conditions for ODE's that improve on classical criteria, to estimates in the spectral theory of some geometric differential operator on Riemannian manifolds with related topological and geometric applications. To keep their investigation basically self-contained, the authors also collect some, more or less known, material which often appears in the literature in various forms and for which they give, in some instances, new proofs according to their specific point of view.
A Complete Classification Of The Isolated Singularities For Nonlinear Elliptic Equations With Inverse Square Potentials
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Author : Florica C. Cîrstea
language : en
Publisher: American Mathematical Soc.
Release Date : 2014-01-08
A Complete Classification Of The Isolated Singularities For Nonlinear Elliptic Equations With Inverse Square Potentials written by Florica C. Cîrstea and has been published by American Mathematical Soc. this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-01-08 with Mathematics categories.
In particular, for b = 1 and λ = 0, we find a sharp condition on h such that the origin is a removable singularity for all non-negative solutions of [[eqref]]one, thus addressing an open question of Vázquez and Véron.
Gromov Cauchy And Causal Boundaries For Riemannian Finslerian And Lorentzian Manifolds
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Author : Jose Luis Flores
language : en
Publisher: American Mathematical Soc.
Release Date : 2013-10-23
Gromov Cauchy And Causal Boundaries For Riemannian Finslerian And Lorentzian Manifolds written by Jose Luis Flores and has been published by American Mathematical Soc. this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-23 with Mathematics categories.
Recently, the old notion of causal boundary for a spacetime V has been redefined consistently. The computation of this boundary ∂V on any standard conformally stationary spacetime V=R×M, suggests a natural compactification MB associated to any Riemannian metric on M or, more generally, to any Finslerian one. The corresponding boundary ∂BM is constructed in terms of Busemann-type functions. Roughly, ∂BM represents the set of all the directions in M including both, asymptotic and "finite" (or "incomplete") directions. This Busemann boundary ∂BM is related to two classical boundaries: the Cauchy boundary ∂CM and the Gromov boundary ∂GM. The authors' aims are: (1) to study the subtleties of both, the Cauchy boundary for any generalized (possibly non-symmetric) distance and the Gromov compactification for any (possibly incomplete) Finsler manifold, (2) to introduce the new Busemann compactification MB, relating it with the previous two completions, and (3) to give a full description of the causal boundary ∂V of any standard conformally stationary spacetime. J. L. Flores and J. Herrera, University of Malaga, Spain, and M. Sánchez, University of Granada, Spain. Publisher's note.
Non Cooperative Equilibria Of Fermi Systems With Long Range Interactions
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Author : Jean-Bernard Bru
language : en
Publisher: American Mathematical Soc.
Release Date : 2013-06-28
Non Cooperative Equilibria Of Fermi Systems With Long Range Interactions written by Jean-Bernard Bru and has been published by American Mathematical Soc. this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-28 with Mathematics categories.
The authors define a Banach space $\mathcal{M}_{1}$ of models for fermions or quantum spins in the lattice with long range interactions and make explicit the structure of (generalized) equilibrium states for any $\mathfrak{m}\in \mathcal{M}_{1}$. In particular, the authors give a first answer to an old open problem in mathematical physics--first addressed by Ginibre in 1968 within a different context--about the validity of the so-called Bogoliubov approximation on the level of states. Depending on the model $\mathfrak{m}\in \mathcal{M}_{1}$, the authors' method provides a systematic way to study all its correlation functions at equilibrium and can thus be used to analyze the physics of long range interactions. Furthermore, the authors show that the thermodynamics of long range models $\mathfrak{m}\in \mathcal{M}_{1}$ is governed by the non-cooperative equilibria of a zero-sum game, called here thermodynamic game.
Operator Valued Measures Dilations And The Theory Of Frames
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Author : Deguang Han
language : en
Publisher: American Mathematical Soc.
Release Date : 2014-04-07
Operator Valued Measures Dilations And The Theory Of Frames written by Deguang Han and has been published by American Mathematical Soc. this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-04-07 with Mathematics categories.
The authors develop elements of a general dilation theory for operator-valued measures. Hilbert space operator-valued measures are closely related to bounded linear maps on abelian von Neumann algebras, and some of their results include new dilation results for bounded linear maps that are not necessarily completely bounded, and from domain algebras that are not necessarily abelian. In the non-cb case the dilation space often needs to be a Banach space. They give applications to both the discrete and the continuous frame theory. There are natural associations between the theory of frames (including continuous frames and framings), the theory of operator-valued measures on sigma-algebras of sets, and the theory of continuous linear maps between -algebras. In this connection frame theory itself is identified with the special case in which the domain algebra for the maps is an abelian von Neumann algebra and the map is normal (i.e. ultraweakly, or weakly, or w*) continuous.
On The Regularity Of The Composition Of Diffeomorphisms
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Author : H. Inci
language : en
Publisher: American Mathematical Soc.
Release Date : 2013-10-23
On The Regularity Of The Composition Of Diffeomorphisms written by H. Inci and has been published by American Mathematical Soc. this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-23 with Mathematics categories.
For M a closed manifold or the Euclidean space Rn we present a detailed proof of regularity properties of the composition of Hs-regular diffeomorphisms of M for s > 12dimM+1.