A Roadmap For Curing Cancer Alzheimer S And Cardiovascular Disease
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A Roadmap For Curing Cancer Alzheimer S And Cardiovascular Disease
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Author : Paul J. Marangos
language : en
Publisher: Academic Press
Release Date : 2017-04-25
A Roadmap For Curing Cancer Alzheimer S And Cardiovascular Disease written by Paul J. Marangos and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-04-25 with Science categories.
Cancer, dementia, and cardiovascular disease are responsible for almost two million deaths each year in the United States alone and represent the largest immediate threat to humanity. Over the last century, we have made spectacular advances that have transformed our society – splitting the atom, space travel, telecommunications, and the Internet – but with medical research focused mostly on science for the sake of science, it has yielded precious few cures. A Roadmap for Curing Cancer, Alzheimer’s, and Cardiovascular Disease represents a "first of its kind" effort to address both the reasons for this and to posit solutions to fix our broken system, in an effort to finally end this cure crisis. Dr. Marangos draws on 45 years of experience in every aspect of the biomedical R&D field, from basic drug discovery research at the NIH to the co-founding of five drug companies. He has published 252 research papers and edited four books on drug discovery, is co-inventor on 14 patents, and founded "The Journal of Molecular Neuroscience". He argues that from a development perspective, the regulatory, patent, and legal hurdles that force industry to pursue so-called "me-too" drugs rather than cures for terminal diseases must be re-thought. Leadership accountability, strategy, focus, and urgency need to be re-evaluated, and major reforms to the NIH, FDA, and patent codes are proposed.to remedy these impediments to cures. Written for anyone frustrated with the seemingly endless threat of terminal disease, this book seeks to inform, energize, and provide the rationale for the public and industry stakeholders, as well as clinicians and researchers, to resurrect the physician-patient relationship and demand that we get serious about ridding society of this scourge on humanity. - This work contains the views and opinions of the author and are in no way intended to harm the reputation of any person, agency, organization, or commercial entity discussed herein. - First comprehensive analysis of the failures in curing cancer, Alzheimer’s, and cardiovascular disease with solutions proposed Defines deficiencies in academic life science research, including conflicting incentives, QA/QC issues, and how to fix them Provides a rationale for FDA reform especially as it relates to terminal disease drugs Details how a reformed NIH, regulators, and industry can partner to form a NASA-type effort to speed cures of terminal diseases Provides the first detailed roadmap for life science researchers to conquer terminal disease
Metabolism And Medicine
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Author : Brian Fertig
language : en
Publisher: CRC Press
Release Date : 2022-01-26
Metabolism And Medicine written by Brian Fertig and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-26 with Science categories.
Chronic disease states of aging should be viewed through the prism of metabolism and biophysical processes at all levels of physiological organization present in the human body. This book describes the building blocks of understanding from a reasonable but not high-level technical language viewpoint, employing the perspective of a clinical physician. It brings together concepts from five specific branches of physics relevant to biology and medicine, namely, biophysics, classical electromagnetism, thermodynamics, systems biology and quantum mechanics. Key Features: Broad and up-to-date overview of the field of metabolism, especially connecting the spectrum of topics that range from modern physical underpinnings with cell biology to clinical practice. Provides a deeper basic science and interdisciplinary understanding of biological systems that broaden the perspectives and therapeutic problem solving. Introduces the concept of the Physiological Fitness Landscape, which is inspired by the physics of phase transitions This first volume in a two-volume set, primarily targets an audience of clinical and science students, biomedical researchers and physicians who would benefit from understanding each other’s language.
The Roadmap To 100
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Author : Walter M. Bortz, II, MD
language : en
Publisher: Palgrave MacMillan
Release Date : 2010-04-13
The Roadmap To 100 written by Walter M. Bortz, II, MD and has been published by Palgrave MacMillan this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-04-13 with Health & Fitness categories.
With a baby boomer turning sixty every ten seconds, we are rapidly becoming an aging society. But cutting edge research on the connection between age and disease shows us that many of the preconceptions we had about how to grow old need a second look. This groundbreaking book is full of take-away prescriptive advice which the nearly seventy-five million boomers in this nation will value. Top gerontologist and Stanford medical school professor Dr. Walter Bortz and co-author Randall Stickrod draw on new science and a thirty-year longitudinal study of centenarians to show that: • Genetics plays a smaller role in aging than previously thought • Senility, dementia, and other diseases of the elderly, are largely preventable and not an inevitable consequence of aging • Engagement, through sexual relationships, social interaction, and professional activity, is a key factor in long, healthy lives • Physical fitness can recover at least 30 years of aging Filled with in-depth insight and practical advice, The Roadmap to 100 gives you the power to control your own destiny and live well beyond 100.
Departments Of Labor Health And Human Services Education And Related Agencies Appropriations For 2006 National Institutes Of Health
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Author : United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies
language : en
Publisher:
Release Date : 2005
Departments Of Labor Health And Human Services Education And Related Agencies Appropriations For 2006 National Institutes Of Health written by United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with Government publications categories.
Departments Of Labor Health And Human Services Education And Related Agencies Appropriations For 2006
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Author : United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies
language : en
Publisher:
Release Date : 2005
Departments Of Labor Health And Human Services Education And Related Agencies Appropriations For 2006 written by United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with United States categories.
The Law Of Biologic Medicine
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Author : United States. Congress. Senate. Committee on the Judiciary
language : en
Publisher:
Release Date : 2004
The Law Of Biologic Medicine written by United States. Congress. Senate. Committee on the Judiciary and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Law categories.
Va Research On Alzheimer S Disease Parkinson S Disease And Diabetes
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Author : United States. Congress. House. Committee on Veterans' Affairs. Subcommittee on Oversight and Investigations
language : en
Publisher:
Release Date : 2005
Va Research On Alzheimer S Disease Parkinson S Disease And Diabetes written by United States. Congress. House. Committee on Veterans' Affairs. Subcommittee on Oversight and Investigations and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with Medical categories.
Departments Of Labor Health And Human Services Education And Related Agencies Appropriations For 2007
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Author : United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies
language : en
Publisher:
Release Date : 2006
Departments Of Labor Health And Human Services Education And Related Agencies Appropriations For 2007 written by United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with United States categories.
Departments Of Labor And Health And Human Services Education And Related Agencies Appropriations
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Author : United States. Congress. Senate. Committee on Appropriations
language : en
Publisher:
Release Date : 2007
Departments Of Labor And Health And Human Services Education And Related Agencies Appropriations written by United States. Congress. Senate. Committee on Appropriations and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with categories.
Metabolic And Bioenergetic Drivers Of Neurodegenerative Disease Treating Neurodegenerative Diseases As Metabolic Diseases
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Author :
language : en
Publisher: Academic Press
Release Date : 2020-08-25
Metabolic And Bioenergetic Drivers Of Neurodegenerative Disease Treating Neurodegenerative Diseases As Metabolic Diseases written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-25 with Medical categories.
Metabolic Drivers and Bioenergetic Components of Neurodegenerative Disease reviews how the different aspects of metabolic dysfunction and consequent pathology associated with neurodegenerative diseases, including Alzheimer’s and Parkinson’s, can be targeted by novel treatment approaches. Topics covered include Cellular Senescence in Aging and Age-Related Disorders: Implications for Neurodegenerative Diseases; Repurposing GLP1 agonists for Neurodegenerative Diseases; Ketotherapeutics for Neurodegenerative Diseases; Enhancing Mitophagy as a Therapeutic Approach for Neurodegenerative Diseases; Harnessing Neurogenesis in the Adult Brain – A Role in Type 2 Diabetes Mellitus and Alzheimer’s disease; and much more. Summarizes the impact of the metabolic hypothesis on underlying mechanisms of neurodegenerative diseases Presents novel, potential treatment strategies based on the metabolic hypothesis for neurodegenerative diseases